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Employment (4)

FibroGen (United States): San Francisco, California, US

2021-07-12 to present | Chief Scientific Officer (Drug Research and Development)
Employment
Source: Self-asserted source
John Hunter

Keyhole Therapeutics, Inc.: San Francisco, CA, US

2020-02 to present | CEO & CSO
Employment
Source: Self-asserted source
John Hunter

Compugen: Tel Aviv, IL

2018-04 to 2020-01 | CSO
Employment
Source: Self-asserted source
John Hunter

Compugen USA Inc: South San Francisco, CA, US

2012-04 to 2018-04 | Vice President and Site Head (Antibody R&D)
Employment
Source: Self-asserted source
John Hunter

Education and qualifications (1)

University of California San Francisco: San Francisco, CA, US

PhD (Microbiology and Immunology)
Education
Source: Self-asserted source
John Hunter

Works (21)

Therapeutic Targeting of Checkpoint Receptors within the DNAM1 Axis

Cancer Discovery
2021-05-01 | Journal article
DOI: 10.1158/2159-8290.cd-20-1248
Part of ISSN: 2159-8274
Part of ISSN: 2159-8290
Source: Self-asserted source
John Hunter
grade
Preferred source (of 2)‎

PVRIG is a novel NK cell immune checkpoint receptor in acute myeloid leukemia.

Haematologica
2020-11-05 | Journal article
DOI: 10.3324/haematol.2020.258574
PMID: 33147937
Source: Self-asserted source
John Hunter

Characterization of BAY 1905254, an Immune Checkpoint Inhibitor Targeting the Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2).

Cancer immunology research
2020-04-20 | Journal article
DOI: 10.1158/2326-6066.cir-19-0321
PMID: 32312711
Source: Self-asserted source
John Hunter

A phase I study evaluating COM701 monotherapy and in combination with nivolumab in patients with advanced solid malignancies.

Journal of Clinical Oncology
2020-02-10 | Journal article
DOI: 10.1200/jco.2020.38.5_suppl.tps23
Part of ISSN: 0732-183X
Contributors: Ryan J. Sullivan; Emerson A. Lim; Manish Sharma; Dale Randall Shepard; Amita Patnaik; Erika Paige Hamilton; Gini F. Fleming; Kyriakos P. Papadopoulos; Adam ElNaggar; Adeboye H. Adewoye et al.
Source: Self-asserted source
John Hunter via Crossref Metadata Search

Abstract 581: Discovery and development of COM701, a therapeutic antibody targeting the novel immune checkpoint PVRIG

Immunology
2017-07-02 | Other
DOI: 10.1158/1538-7445.am2017-581
Contributors: Ofer Levy; Chris Chan; Gady Cojocaru; Spencer Liang; Eran Ophir; Sudipto Ganguly; Maya Kotturi; Tal Friedman; Benjamin Murter; Liat Dassa et al.
Source: Self-asserted source
John Hunter via Crossref Metadata Search

Monoclonal antibodies targeting IL-1 beta reduce biomarkers of atherosclerosis in vitro and inhibit atherosclerotic plaque formation in Apolipoprotein E-deficient mice.

Atherosclerosis
2011-02-24 | Journal article
DOI: 10.1016/j.atherosclerosis.2011.02.026
PMID: 21411094
Source: Self-asserted source
John Hunter

Kinetic approach to pathway attenuation using XOMA 052, a regulatory therapeutic antibody that modulates interleukin-1beta activity.

The Journal of biological chemistry
2010-04-21 | Journal article
DOI: 10.1074/jbc.m110.115790
PMID: 20410301
PMC: PMC2898365
Source: Self-asserted source
John Hunter

Localization of human TACC3 to mitotic spindles is mediated by phosphorylation on Ser558 by Aurora A: a novel pharmacodynamic method for measuring Aurora A activity.

Cancer research
2007-06-01 | Journal article
DOI: 10.1158/0008-5472.can-07-0122
PMID: 17545617
Source: Self-asserted source
John Hunter

Noninvasive Bioluminescence Imaging of Normal and Spontaneously Transformed Prostate Tissue in Mice

Cancer Research
2006-05-01 | Journal article
DOI: 10.1158/0008-5472.can-05-3598
Part of ISSN: 0008-5472
Part of ISSN: 1538-7445
Contributors: John Hunter; Scott K. Lyons; Ed Lim; Anne O. Clermont; Joan Dusich; Lingyun Zhu; Kenneth D. Campbell; Richard J. Coffee; David S. Grass; John Hunter et al.
Source: Self-asserted source
John Hunter

Detection of Activity Centers in Cellular Pathways Using Transcript Profiling

Journal of Biopharmaceutical Statistics
2004-12-29 | Journal article
DOI: 10.1081/bip-200025678
Part of ISSN: 1054-3406
Part of ISSN: 1520-5711
Contributors: John Hunter; Joel Pradines; Laura Rudolph-Owen; John Hunter; Patrick Leroy; Michael Cary; Robert Coopersmith; Vlado Dancik; Yelena Eltsefon; Victor Farutin et al.
Source: Self-asserted source
John Hunter

Human melastatin 1 (TRPM1) is regulated by MITF and produces multiple polypeptide isoforms in melanocytes and melanoma.

Melanoma research
2004-12-01 | Journal article
DOI: 10.1097/00008390-200412000-00011
PMID: 15577322
Source: Self-asserted source
John Hunter

Chromosomal localization and genomic characterization of the mouse melastatin gene (Mlsn1).

Genomics
1998-11-01 | Journal article
DOI: 10.1006/geno.1998.5549
PMID: 9806836
Source: Self-asserted source
John Hunter

Characterization of the nuclear export signal of human T-cell lymphotropic virus type 1 Rex reveals that nuclear export is mediated by position-variable hydrophobic interactions.

Molecular and cellular biology
1996-09-01 | Journal article
DOI: 10.1128/mcb.16.9.5147
PMID: 8756672
PMC: PMC231515
Source: Self-asserted source
John Hunter

Evidence for alpha-helical conformation of an essential N-terminal region in the human Bcl2 protein.

The Journal of biological chemistry
1996-09-01 | Journal article
DOI: 10.1074/jbc.271.38.23284
PMID: 8798527
Source: Self-asserted source
John Hunter

A peptide sequence from Bax that converts Bcl-2 into an activator of apoptosis.

The Journal of biological chemistry
1996-04-01 | Journal article
DOI: 10.1074/jbc.271.15.8521
PMID: 8621473
Source: Self-asserted source
John Hunter

Functional dissection of the human Bcl2 protein: sequence requirements for inhibition of apoptosis.

Molecular and cellular biology
1996-03-01 | Journal article
DOI: 10.1128/mcb.16.3.877
PMID: 8622689
PMC: PMC231068
Source: Self-asserted source
John Hunter

cDNA cloning of mouse NKR-P1 and genetic linkage with LY-49. Identification of a natural killer cell gene complex on mouse chromosome 6.

Journal of immunology (Baltimore, Md. : 1950)
1991-11-01 | Journal article
PMID: 1680927
Source: Self-asserted source
John Hunter

Role of abortive retroviral infection of neurons in spongiform CNS degeneration.

Nature
1990-07-01 | Journal article
DOI: 10.1038/346181a0
PMID: 2195355
Source: Self-asserted source
John Hunter

Maternal transmission of retroviral disease and strategies for preventing infection of the neonate.

Journal of virology
1989-03-01 | Journal article
DOI: 10.1128/jvi.63.3.1049-1053.1989
PMID: 2915376
PMC: PMC247797
Source: Self-asserted source
John Hunter

Maternal transmission of retroviral disease: transgenic mice as a rapid test system for evaluating perinatal and transplacental antiretroviral therapy.

Proceedings of the National Academy of Sciences of the United States of America
1988-12-01 | Journal article
DOI: 10.1073/pnas.85.24.9792
PMID: 2849117
PMC: PMC282867
Source: Self-asserted source
John Hunter

COM902, a novel therapeutic antibody targeting TIGIT augments anti-tumor T cell function in combination with PVRIG or PD-1 pathway blockade

Cancer Immunology Immunotherapy
Journal article
DOI: 10.1007/s00262-021-02921-8
Source: Self-asserted source
John Hunter
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