Personal information

Keywords

Epigenetics, Chromatin, Cancer, Stem cells, DNA methylation

Countries

Canada

Activities

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Employment (2)

The Hospital for Sick Children: Toronto, ON, CA

2018-08-01 to 2021-06-30 | Research Associate (Brain Tumour Research Centre)
Employment
Source: Self-asserted source
Paul Guilhamon

University Health Network: Toronto, ON, CA

2015-01-05 to 2018-07-31 | Postdoctoral Research Fellow (Princess Margaret Cancer Centre)
Employment
Source: Self-asserted source
Paul Guilhamon

Education and qualifications (2)

University College London: London, London, GB

2010-09-15 to 2014-11-15 | PhD (Cancer Institute)
Education
Source: Self-asserted source
Paul Guilhamon

University of Oxford: Oxford, Oxfordshire, GB

2006-10-01 to 2010-06-01 | MBiochem (Biochemistry)
Education
Source: Self-asserted source
Paul Guilhamon

Funding (2)

Integrated Genomic and Epigenomic Analysis of Regulatory Elements in Glioblastoma

2015-08-01 to 2018-07-31 | Grant
Canadian Institutes of Health Research (Ottawa, CA)
URL: https://grants.uberresearch.com/501100000024/5ccd4abe40892f50483ee0aab7a00d2f/Integrated-Genomic-and-Epigenomic-Analysis-of-Regulatory-Elements-in-Glioblastoma
GRANT_NUMBER:

grant.5ccd4abe40892f50483ee0aab7a00d2f
Source: Self-asserted source
Paul Guilhamon via DimensionsWizard

Integrated genomic and epigenomic analysis of osteosarcomas

2010-09 to 2014-10 | Award
Research Councils UK (London, London, GB)
GRANT_NUMBER:

G100041
Source: Self-asserted source
Paul Guilhamon

Works (19)

Single-cell chromatin accessibility profiling of glioblastoma identifies an invasive cancer stem cell population associated with lower survival

eLife
2021-01-11 | Journal article
DOI: 10.7554/eLife.64090
Contributors: Paul Guilhamon; Charles Chesnelong; Michelle M Kushida; Ana Nikolic; Divya Singhal; Graham MacLeod; Seyed Ali Madani Tonekaboni; Florence MG Cavalli; Christopher Arlidge; Nishani Rajakulendran et al.
Source: check_circle
Crossref

High-resolution structural genomics reveals new therapeutic vulnerabilities in glioblastoma

Genome Research
2019-08 | Journal article
DOI: 10.1101/gr.246520.118
Part of ISSN: 1088-9051
Part of ISSN: 1549-5469
Source: Self-asserted source
Paul Guilhamon

A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor

Cancer Cell
2019-07 | Journal article
DOI: 10.1016/j.ccell.2019.06.002
Part of ISSN: 1535-6108
Source: Self-asserted source
Paul Guilhamon

Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas

Cancer Cell
2019-05 | Journal article
DOI: 10.1016/j.ccell.2019.04.004
Part of ISSN: 1535-6108
Source: Self-asserted source
Paul Guilhamon

C3D: a tool to predict 3D genomic interactions between cis-regulatory elements

Bioinformatics
2019-03-01 | Journal article
DOI: 10.1093/bioinformatics/bty717
DOI: 10.1101/197301
Part of ISSN: 1367-4803
Part of ISSN: 1460-2059
Source: Self-asserted source
Paul Guilhamon
grade
Preferred source (of 2)‎

SMuRF: a novel tool to identify regulatory elements enriched for somatic point mutations

BMC Bioinformatics
2018-12 | Journal article
DOI: 10.1101/271957
DOI: 10.1186/s12859-018-2501-y
ISSN: 1471-2105
Source: Self-asserted source
Paul Guilhamon
grade
Preferred source (of 2)‎

Single-cell chromatin accessibility in glioblastoma delineates cancer stem cell heterogeneity predictive of survival

2018-07-17 | Other
DOI: 10.1101/370726
Contributors: P. Guilhamon; M.M. Kushida; A. Nikolic; D. Singhal; G. MacLeod; S.A. Madani Tonekaboni; F.M.G. Cavalli; C. Arlidge; N. Rajakulendran; N. Rastegar et al.
Source: check_circle
Crossref

Convergence of BMI1 and CHD7 on ERK Signaling in Medulloblastoma.

Cell reports
2017-12 | Journal article
DOI: 10.1016/j.celrep.2017.11.021
PMID: 29212025
PMC: PMC5732319
Contributors: Badodi S; Dubuc A; Zhang X; Rosser G; Da Cunha Jaeger M; Kameda-Smith MM; Morrissy AS; Guilhamon P; Suetterlin P; Li XN et al.
Source: Self-asserted source
Paul Guilhamon via Europe PubMed Central

ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells.

Cell stem cell
2017-09 | Journal article
DOI: 10.1016/j.stem.2017.08.008
PMID: 28886368
Contributors: Park NI; Guilhamon P; Desai K; McAdam RF; Langille E; O'Connor M; Lan X; Whetstone H; Coutinho FJ; Vanner RJ et al.
Source: Self-asserted source
Paul Guilhamon via Europe PubMed Central

Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy.

Nature
2017-09 | Journal article
DOI: 10.1038/nature23666
PMID: 28854171
Contributors: Lan X; Jörg DJ; Cavalli FMG; Richards LM; Nguyen LV; Vanner RJ; Guilhamon P; Lee L; Kushida MM; Pellacani D et al.
Source: Self-asserted source
Paul Guilhamon via Europe PubMed Central

ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells.

Cell stem cell
2017-08 | Journal article
DOI: 10.1016/j.stem.2017.06.004
PMID: 28712938
Contributors: Park NI; Guilhamon P; Desai K; McAdam RF; Langille E; O'Connor M; Lan X; Whetstone H; Coutinho FJ; Vanner RJ et al.
Source: Self-asserted source
Paul Guilhamon via Europe PubMed Central

Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors.

Cancer cell
2016-12 | Journal article
DOI: 10.1016/j.ccell.2016.11.003
PMID: 27960086
PMC: PMC5500911
Contributors: Torchia J; Golbourn B; Feng S; Ho KC; Sin-Chan P; Vasiljevic A; Norman JD; Guilhamon P; Garzia L; Agamez NR et al.
Source: Self-asserted source
Paul Guilhamon via Europe PubMed Central

Comparative methylome analysis identifies new tumour subtypes and biomarkers for transformation of nephrogenic rests into Wilms tumour.

Genome medicine
2015 | Journal article
DOI: 10.1186/s13073-015-0136-4
PMID: 25763109
PMC: PMC4354990
Contributors: Charlton J; Williams RD; Sebire NJ; Popov S; Vujanic G; Chagtai T; Alcaide-German M; Morris T; Butcher LM; Guilhamon P et al.
Source: Self-asserted source
Paul Guilhamon via Europe PubMed Central

oxBS-450K: a method for analysing hydroxymethylation using 450K BeadChips.

Methods (San Diego, Calif.)
2015-01 | Journal article
DOI: 10.1016/j.ymeth.2014.08.009
PMID: 25175075
PMC: PMC4304834
Contributors: Stewart SK; Morris TJ; Guilhamon P; Bulstrode H; Bachman M; Balasubramanian S; Beck S
Source: Self-asserted source
Paul Guilhamon via Europe PubMed Central

Assessment of patient-derived tumour xenografts (PDXs) as a discovery tool for cancer epigenomics.

Genome medicine
2014 | Journal article
DOI: 10.1186/s13073-014-0116-0
PMID: 25587359
PMC: PMC4292812
Contributors: Guilhamon P; Butcher LM; Presneau N; Wilson GA; Feber A; Paul DS; Schütte M; Haybaeck J; Keilholz U; Hoffman J et al.
Source: Self-asserted source
Paul Guilhamon via Europe PubMed Central

Mucosal transcriptomics implicates under expression of BRINP3 in the pathogenesis of ulcerative colitis.

Inflammatory bowel diseases
2014-10 | Journal article
DOI: 10.1097/mib.0000000000000169
PMID: 25171508
PMC: PMC4531309
Contributors: Smith PJ; Levine AP; Dunne J; Guilhamon P; Turmaine M; Sewell GW; OʼShea NR; Vega R; Paterson JC; Oukrif D et al.
Source: Self-asserted source
Paul Guilhamon via Europe PubMed Central

Assessment of RainDrop BS-seq as a method for large-scale, targeted bisulfite sequencing.

Epigenetics
2014-05 | Journal article
DOI: 10.4161/epi.28041
PMID: 24518816
PMC: PMC4063826
Contributors: Paul DS; Guilhamon P; Karpathakis A; Butcher LM; Thirlwell C; Feber A; Beck S
Source: Self-asserted source
Paul Guilhamon via Europe PubMed Central

Using high-density DNA methylation arrays to profile copy number alterations.

Genome biology
2014-02 | Journal article
DOI: 10.1186/gb-2014-15-2-r30
PMID: 24490765
PMC: PMC4054098
Contributors: Feber A; Guilhamon P; Lechner M; Fenton T; Wilson GA; Thirlwell C; Morris TJ; Flanagan AM; Teschendorff AE; Kelly JD et al.
Source: Self-asserted source
Paul Guilhamon via Europe PubMed Central

Meta-analysis of IDH-mutant cancers identifies EBF1 as an interaction partner for TET2.

Nature communications
2013 | Journal article
DOI: 10.1038/ncomms3166
PMID: 23863747
PMC: PMC3759038
Contributors: Guilhamon P; Eskandarpour M; Halai D; Wilson GA; Feber A; Teschendorff AE; Gomez V; Hergovich A; Tirabosco R; Fernanda Amary M et al.
Source: Self-asserted source
Paul Guilhamon via Europe PubMed Central
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