Personal information

Other IDs

SciProfiles: 1604520

Activities

Collapse all

Employment (4)

Superior Medical Experts: St. Paul, Minnesota, US

2021-06-15 to present | Director of Research
Employment
Source: Self-asserted source
Erin Sheffels

Superior Medical Experts: Minneapolis, MN, US

2020-12-01 to 2021-06-15 | Medical Writer
Employment
Source: Self-asserted source
Erin Sheffels

Henry M. Jackson Foundation: Bethesda, Maryland, US

2020-05-05 to 2021-04-01 | Research Associate (USUHS, Department of Pharmacology and Molecular Therapeutics)
Employment
Source: Self-asserted source
Erin Sheffels

Reed College: Portland, OR, US

2012-06 to 2014-05 | Reactor Operator (Reed Research Reactor)
Employment
Source: Self-asserted source
Erin Sheffels

Education and qualifications (2)

Uniformed Services University of the Health Sciences: Bethesda, MD, US

2015-08 to 2020-05-15 | PhD, Molecular and Cell Biology (Department of Pharmacology and Molecular Therapeutics)
Education
Source: Self-asserted source
Erin Sheffels

Reed College: Portland, OR, US

2010-08 to 2014-05 | BA, Biochemistry and Molecular Biology
Education
Source: Self-asserted source
Erin Sheffels

Works (34)

Data from SOS1 Inhibition Enhances the Efficacy of KRAS<sup>G12C</sup> Inhibitors and Delays Resistance in Lung Adenocarcinoma

2025-01-02 | Preprint
DOI: 10.1158/0008-5472.c.7606522
Contributors: Brianna R. Daley; Nancy E. Sealover; Bridget A. Finniff; Jacob M. Hughes; Erin Sheffels; Daniel Gerlach; Marco H. Hofmann; Kaja Kostyrko; Joseph P. LaMorte; Amanda J. Linke et al.
Source: check_circle
Crossref

Figure S1 from SOS1 Inhibition Enhances the Efficacy of KRAS<sup>G12C</sup> Inhibitors and Delays Resistance in Lung Adenocarcinoma

2025-01-02 | Preprint
DOI: 10.1158/0008-5472.28122781
Contributors: Brianna R. Daley; Nancy E. Sealover; Bridget A. Finniff; Jacob M. Hughes; Erin Sheffels; Daniel Gerlach; Marco H. Hofmann; Kaja Kostyrko; Joseph P. LaMorte; Amanda J. Linke et al.
Source: check_circle
Crossref

Figure S10 from SOS1 Inhibition Enhances the Efficacy of KRAS<sup>G12C</sup> Inhibitors and Delays Resistance in Lung Adenocarcinoma

2025-01-02 | Preprint
DOI: 10.1158/0008-5472.28122778
Contributors: Brianna R. Daley; Nancy E. Sealover; Bridget A. Finniff; Jacob M. Hughes; Erin Sheffels; Daniel Gerlach; Marco H. Hofmann; Kaja Kostyrko; Joseph P. LaMorte; Amanda J. Linke et al.
Source: check_circle
Crossref

Figure S11 from SOS1 Inhibition Enhances the Efficacy of KRAS<sup>G12C</sup> Inhibitors and Delays Resistance in Lung Adenocarcinoma

2025-01-02 | Preprint
DOI: 10.1158/0008-5472.28122775
Contributors: Brianna R. Daley; Nancy E. Sealover; Bridget A. Finniff; Jacob M. Hughes; Erin Sheffels; Daniel Gerlach; Marco H. Hofmann; Kaja Kostyrko; Joseph P. LaMorte; Amanda J. Linke et al.
Source: check_circle
Crossref

Figure S12 from SOS1 Inhibition Enhances the Efficacy of KRAS<sup>G12C</sup> Inhibitors and Delays Resistance in Lung Adenocarcinoma

2025-01-02 | Preprint
DOI: 10.1158/0008-5472.28122772
Contributors: Brianna R. Daley; Nancy E. Sealover; Bridget A. Finniff; Jacob M. Hughes; Erin Sheffels; Daniel Gerlach; Marco H. Hofmann; Kaja Kostyrko; Joseph P. LaMorte; Amanda J. Linke et al.
Source: check_circle
Crossref

Figure S13 from SOS1 Inhibition Enhances the Efficacy of KRAS<sup>G12C</sup> Inhibitors and Delays Resistance in Lung Adenocarcinoma

2025-01-02 | Preprint
DOI: 10.1158/0008-5472.28122769
Contributors: Brianna R. Daley; Nancy E. Sealover; Bridget A. Finniff; Jacob M. Hughes; Erin Sheffels; Daniel Gerlach; Marco H. Hofmann; Kaja Kostyrko; Joseph P. LaMorte; Amanda J. Linke et al.
Source: check_circle
Crossref

Figure S14 from SOS1 Inhibition Enhances the Efficacy of KRAS<sup>G12C</sup> Inhibitors and Delays Resistance in Lung Adenocarcinoma

2025-01-02 | Preprint
DOI: 10.1158/0008-5472.28122766
Contributors: Brianna R. Daley; Nancy E. Sealover; Bridget A. Finniff; Jacob M. Hughes; Erin Sheffels; Daniel Gerlach; Marco H. Hofmann; Kaja Kostyrko; Joseph P. LaMorte; Amanda J. Linke et al.
Source: check_circle
Crossref

Figure S15 from SOS1 Inhibition Enhances the Efficacy of KRAS<sup>G12C</sup> Inhibitors and Delays Resistance in Lung Adenocarcinoma

2025-01-02 | Preprint
DOI: 10.1158/0008-5472.28122763
Contributors: Brianna R. Daley; Nancy E. Sealover; Bridget A. Finniff; Jacob M. Hughes; Erin Sheffels; Daniel Gerlach; Marco H. Hofmann; Kaja Kostyrko; Joseph P. LaMorte; Amanda J. Linke et al.
Source: check_circle
Crossref

Figure S16 from SOS1 Inhibition Enhances the Efficacy of KRAS<sup>G12C</sup> Inhibitors and Delays Resistance in Lung Adenocarcinoma

2025-01-02 | Preprint
DOI: 10.1158/0008-5472.28122760
Contributors: Brianna R. Daley; Nancy E. Sealover; Bridget A. Finniff; Jacob M. Hughes; Erin Sheffels; Daniel Gerlach; Marco H. Hofmann; Kaja Kostyrko; Joseph P. LaMorte; Amanda J. Linke et al.
Source: check_circle
Crossref

Figure S17 from SOS1 Inhibition Enhances the Efficacy of KRAS<sup>G12C</sup> Inhibitors and Delays Resistance in Lung Adenocarcinoma

2025-01-02 | Preprint
DOI: 10.1158/0008-5472.28122757
Contributors: Brianna R. Daley; Nancy E. Sealover; Bridget A. Finniff; Jacob M. Hughes; Erin Sheffels; Daniel Gerlach; Marco H. Hofmann; Kaja Kostyrko; Joseph P. LaMorte; Amanda J. Linke et al.
Source: check_circle
Crossref

Figure S18 from SOS1 Inhibition Enhances the Efficacy of KRAS<sup>G12C</sup> Inhibitors and Delays Resistance in Lung Adenocarcinoma

2025-01-02 | Preprint
DOI: 10.1158/0008-5472.28122754
Contributors: Brianna R. Daley; Nancy E. Sealover; Bridget A. Finniff; Jacob M. Hughes; Erin Sheffels; Daniel Gerlach; Marco H. Hofmann; Kaja Kostyrko; Joseph P. LaMorte; Amanda J. Linke et al.
Source: check_circle
Crossref

Figure S19 from SOS1 Inhibition Enhances the Efficacy of KRAS<sup>G12C</sup> Inhibitors and Delays Resistance in Lung Adenocarcinoma

2025-01-02 | Preprint
DOI: 10.1158/0008-5472.28122751
Contributors: Brianna R. Daley; Nancy E. Sealover; Bridget A. Finniff; Jacob M. Hughes; Erin Sheffels; Daniel Gerlach; Marco H. Hofmann; Kaja Kostyrko; Joseph P. LaMorte; Amanda J. Linke et al.
Source: check_circle
Crossref

Figure S2 from SOS1 Inhibition Enhances the Efficacy of KRAS<sup>G12C</sup> Inhibitors and Delays Resistance in Lung Adenocarcinoma

2025-01-02 | Preprint
DOI: 10.1158/0008-5472.28122748
Contributors: Brianna R. Daley; Nancy E. Sealover; Bridget A. Finniff; Jacob M. Hughes; Erin Sheffels; Daniel Gerlach; Marco H. Hofmann; Kaja Kostyrko; Joseph P. LaMorte; Amanda J. Linke et al.
Source: check_circle
Crossref

Figure S20 from SOS1 Inhibition Enhances the Efficacy of KRAS<sup>G12C</sup> Inhibitors and Delays Resistance in Lung Adenocarcinoma

2025-01-02 | Preprint
DOI: 10.1158/0008-5472.28122745
Contributors: Brianna R. Daley; Nancy E. Sealover; Bridget A. Finniff; Jacob M. Hughes; Erin Sheffels; Daniel Gerlach; Marco H. Hofmann; Kaja Kostyrko; Joseph P. LaMorte; Amanda J. Linke et al.
Source: check_circle
Crossref

Figure S21 from SOS1 Inhibition Enhances the Efficacy of KRAS<sup>G12C</sup> Inhibitors and Delays Resistance in Lung Adenocarcinoma

2025-01-02 | Preprint
DOI: 10.1158/0008-5472.28122742
Contributors: Brianna R. Daley; Nancy E. Sealover; Bridget A. Finniff; Jacob M. Hughes; Erin Sheffels; Daniel Gerlach; Marco H. Hofmann; Kaja Kostyrko; Joseph P. LaMorte; Amanda J. Linke et al.
Source: check_circle
Crossref

Figure S3 from SOS1 Inhibition Enhances the Efficacy of KRAS<sup>G12C</sup> Inhibitors and Delays Resistance in Lung Adenocarcinoma

2025-01-02 | Preprint
DOI: 10.1158/0008-5472.28122736
Contributors: Brianna R. Daley; Nancy E. Sealover; Bridget A. Finniff; Jacob M. Hughes; Erin Sheffels; Daniel Gerlach; Marco H. Hofmann; Kaja Kostyrko; Joseph P. LaMorte; Amanda J. Linke et al.
Source: check_circle
Crossref

Figure S4 from SOS1 Inhibition Enhances the Efficacy of KRAS<sup>G12C</sup> Inhibitors and Delays Resistance in Lung Adenocarcinoma

2025-01-02 | Preprint
DOI: 10.1158/0008-5472.28122733
Contributors: Brianna R. Daley; Nancy E. Sealover; Bridget A. Finniff; Jacob M. Hughes; Erin Sheffels; Daniel Gerlach; Marco H. Hofmann; Kaja Kostyrko; Joseph P. LaMorte; Amanda J. Linke et al.
Source: check_circle
Crossref

Figure S5 from SOS1 Inhibition Enhances the Efficacy of KRAS<sup>G12C</sup> Inhibitors and Delays Resistance in Lung Adenocarcinoma

2025-01-02 | Preprint
DOI: 10.1158/0008-5472.28122730
Contributors: Brianna R. Daley; Nancy E. Sealover; Bridget A. Finniff; Jacob M. Hughes; Erin Sheffels; Daniel Gerlach; Marco H. Hofmann; Kaja Kostyrko; Joseph P. LaMorte; Amanda J. Linke et al.
Source: check_circle
Crossref

Figure S6 from SOS1 Inhibition Enhances the Efficacy of KRAS<sup>G12C</sup> Inhibitors and Delays Resistance in Lung Adenocarcinoma

2025-01-02 | Preprint
DOI: 10.1158/0008-5472.28122727
Contributors: Brianna R. Daley; Nancy E. Sealover; Bridget A. Finniff; Jacob M. Hughes; Erin Sheffels; Daniel Gerlach; Marco H. Hofmann; Kaja Kostyrko; Joseph P. LaMorte; Amanda J. Linke et al.
Source: check_circle
Crossref

Figure S7 from SOS1 Inhibition Enhances the Efficacy of KRAS<sup>G12C</sup> Inhibitors and Delays Resistance in Lung Adenocarcinoma

2025-01-02 | Preprint
DOI: 10.1158/0008-5472.28122724
Contributors: Brianna R. Daley; Nancy E. Sealover; Bridget A. Finniff; Jacob M. Hughes; Erin Sheffels; Daniel Gerlach; Marco H. Hofmann; Kaja Kostyrko; Joseph P. LaMorte; Amanda J. Linke et al.
Source: check_circle
Crossref

Figure S8 from SOS1 Inhibition Enhances the Efficacy of KRAS<sup>G12C</sup> Inhibitors and Delays Resistance in Lung Adenocarcinoma

2025-01-02 | Preprint
DOI: 10.1158/0008-5472.28122721
Contributors: Brianna R. Daley; Nancy E. Sealover; Bridget A. Finniff; Jacob M. Hughes; Erin Sheffels; Daniel Gerlach; Marco H. Hofmann; Kaja Kostyrko; Joseph P. LaMorte; Amanda J. Linke et al.
Source: check_circle
Crossref

Figure S9 from SOS1 Inhibition Enhances the Efficacy of KRAS<sup>G12C</sup> Inhibitors and Delays Resistance in Lung Adenocarcinoma

2025-01-02 | Preprint
DOI: 10.1158/0008-5472.28122718
Contributors: Brianna R. Daley; Nancy E. Sealover; Bridget A. Finniff; Jacob M. Hughes; Erin Sheffels; Daniel Gerlach; Marco H. Hofmann; Kaja Kostyrko; Joseph P. LaMorte; Amanda J. Linke et al.
Source: check_circle
Crossref

SOS1 Inhibition Enhances the Efficacy of KRASG12C Inhibitors and Delays Resistance in Lung Adenocarcinoma

Cancer Research
2025-01-02 | Journal article
DOI: 10.1158/0008-5472.CAN-23-3256
Contributors: Brianna R. Daley; Nancy E. Sealover; Bridget A. Finniff; Jacob M. Hughes; Erin Sheffels; Daniel Gerlach; Marco H. Hofmann; Kaja Kostyrko; Joseph P. LaMorte; Amanda J. Linke et al.
Source: check_circle
Crossref

Comparison of Balloon Guide Catheters and Standard Guide Catheters for Acute Ischemic Stroke: An Updated Systematic Review and Meta-analysis

World Neurosurgery
2024-05 | Journal article
DOI: 10.1016/j.wneu.2024.01.110
Contributors: John M. Pederson; Nicole Hardy; Hannah Lyons; Erin Sheffels; Jillienne C. Touchette; Waleed Brinjikji; David F. Kallmes; Kevin M. Kallmes
Source: check_circle
Crossref

Evaluation of Post-Operative Outcomes of Femoral Neck Fracture Interventions: A Systematic Review

Geriatric Orthopaedic Surgery & Rehabilitation
2024-01 | Journal article
DOI: 10.1177/21514593241273326
Contributors: Erin Sheffels; Mariam Khalil; Kristen Hutchison; Nicole J. Hardy; Ranita Tarchand; John M. Pederson; Anjani Parikh; Michael Blauth
Source: check_circle
Crossref

The efficacy of prophylactic vertebroplasty for preventing proximal junctional complications after spinal fusion: a systematic review

The Spine Journal
2022-12 | Journal article
DOI: 10.1016/j.spinee.2022.07.104
Contributors: Roman Rahmani; Milo Sanda; Erin Sheffels; Amy Singleton; Samuel D. Stegelmann; Bernadette Kane; Thomas G. Andreshak
Source: check_circle
Crossref

Peripheral Nerve Blocks Outperform General Anesthesia for Pain Control in Arthroscopic Rotator Cuff Repair: A Systematic Review and Meta-analysis

Arthroscopy: The Journal of Arthroscopic & Related Surgery
2022-05 | Journal article
DOI: 10.1016/j.arthro.2021.11.054
Contributors: Andrew Kalthoff; Milo Sanda; Patrick Tate; Kirk Evanson; John M. Pederson; Geeta S. Paranjape; Puja D. Patel; Erin Sheffels; Richard Miller; Anil Gupta
Source: check_circle
Crossref

Patient outcomes after treatment of brain aneurysm in small diameter vessels with the silk vista baby flow diverter: A systematic review.

Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences
2022-04-07 | Journal article
DOI: 10.1177/15910199221091645
PMID: 35392703
Source: Self-asserted source
Erin Sheffels

The effect of instrumentation staging on patient outcomes in pyogenic vertebral osteomyelitis: A systematic review

North American Spine Society Journal (NASSJ)
2021-12 | Journal article
DOI: 10.1016/j.xnsj.2021.100083
Contributors: Milo Sanda; Amy Singleton; Jae Yim; Roman Rahmani; Erin Sheffels; Thomas Andreshak
Source: check_circle
Crossref

The Role of Wild-Type RAS in Oncogenic RAS Transformation

Genes
2021-04-28 | Journal article
DOI: 10.3390/genes12050662
Contributors: Erin Sheffels; Robert L. Kortum
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Anchorage-independent growth conditions reveal a differential SOS2 dependence for transformation and survival in RAS-mutant cancer cells

Small GTPases
2021-01-02 | Journal article
DOI: 10.1080/21541248.2019.1611168
Contributors: Erin Sheffels; Nancy E. Sealover; Patricia L. Theard; Robert L. Kortum
Source: check_circle
Crossref

Marked Synergy by Vertical Inhibition of EGFR signaling in NSCLC Spheroids: SOS1 as a therapeutic target in EGFR-mutated cancer

2020-04-30 | Preprint
DOI: 10.1101/2020.04.28.066241
Contributors: Patricia L. Theard; Erin Sheffels; Nancy E. Sealover; Amanda J. Linke; David J. Pratico; Robert L. Kortum
Source: check_circle
Crossref

Distinct Binding Preferences between Ras and Raf Family Members and the Impact on Oncogenic Ras Signaling.

Molecular cell
2019-10-09 | Journal article
DOI: 10.1016/j.molcel.2019.09.004
PMID: 31606273
PMC: PMC7001861
Source: Self-asserted source
Erin Sheffels

Oncogenic RAS isoforms show a hierarchical requirement for the guanine nucleotide exchange factor SOS2 to mediate cell transformation

Science Signaling
2018-09-04 | Journal article
DOI: 10.1126/scisignal.aar8371
Part of ISSN: 1945-0877
Contributors: Erin Sheffels; Nancy E. Sealover; Chenyue Wang; Do Hyung Kim; Isabella A. Vazirani; Elizabeth Lee; Elizabeth M. Terrell; Deborah K. Morrison; Ji Luo; Robert L. Kortum
Source: Self-asserted source
Erin Sheffels via Crossref Metadata Search
grade
Preferred source (of 2)‎
How many people are using ORCID?