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Works (4)

The carboxyl-terminal sequence of PUMA binds to both anti-apoptotic proteins and membranes

eLife
2023-04-20 | Journal article
DOI: 10.7554/eLife.88329
Contributors: James M Pemberton; Dang Nguyen; Elizabeth J Osterlund; Wiebke Schormann; Justin P Pogmore; Nehad Hirmiz; Brian Leber; David W Andrews
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Efficacy and specificity of inhibitors of BCL-2 family protein interactions assessed by affinity measurements in live cells

Science Advances
2022-04-22 | Journal article
DOI: 10.1126/sciadv.abm7375
Contributors: Elizabeth J. Osterlund; Nehad Hirmiz; James M. Pemberton; Adrien Nougarède; Qian Liu; Brian Leber; Qiyin Fang; David W. Andrews
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Rapid 3D phenotypic analysis of neurons and organoids using data-driven cell segmentation-free machine learning

PLOS Computational Biology
2021-02-22 | Journal article
DOI: 10.1371/journal.pcbi.1008630
Contributors: Philipp Mergenthaler; Jeffrey J. Saucerman; Santosh Hariharan; James M. Pemberton; Corey Lourenco; Linda Z. Penn; David W. Andrews
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The carboxyl-terminal sequence of bim enables bax activation and killing of unprimed cells

eLife
2020-01-24 | Journal article
DOI: 10.7554/eLife.44525
Contributors: Xiaoke Chi; Dang Nguyen; James M Pemberton; Elizabeth J Osterlund; Qian Liu; Hetal Brahmbhatt; Zhi Zhang; Jialing Lin; Brian Leber; David W Andrews
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