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Employment (1)

Northwestern University - Chicago: Chicago, IL, US

1988-04-01 to present | Professor (Microbiology-Immunology)
Employment
Source: Self-asserted source
H Seifert

Education and qualifications (2)

Pennsylvania State University University Park: University Park, PA, US

1979-09-01 to 1984-01-13 | PhD (Microbiology)
Education
Source: Self-asserted source
H Seifert

Beloit College: Beloit, WI, US

1973-09-01 to 1977-06-10 | BS (Chemistry)
Education
Source: Self-asserted source
H Seifert

Works (20)

Natural compounds target the M23B zinc metallopeptidase Mpg to modulate Neisseria gonorrhoeae Type IV pilus expression

mBio
2025-02-25 | Journal article
DOI: 10.1128/mbio.04027-24
Contributors: Kathleen R. Nicholson; Shaohui Yin; Jennifer L. Edwards; Chi-Hao Luan; H Steven Seifert; Sheryl Justice
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Crossref

Torsional Twist of the SARS-CoV and SARS-CoV-2 SUD-N and SUD-M domains

2024-08-14 | Preprint
DOI: 10.1101/2024.08.13.607777
Contributors: Monica Rosas-Lemus; George Minasov; Joseph S. Brunzelle; Taha Y. Taha; Sofia Lemak; Shaohui Yin; Ludmilla Shuvalova; Julia Rosecrans; Kanika Khanna; H Steven Seifert et al.
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Crossref

Development and implementation of a Type I-C CRISPR-based programmable repression system for Neisseria gonorrhoeae

mBio
2024-02-14 | Journal article
DOI: 10.1128/mbio.03025-23
Contributors: Wendy E. Geslewitz; Amaris Cardenas; Xufei Zhou; Yan Zhang; Alison K. Criss; H Steven Seifert; Steven J. Norris
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Crossref

The Neisseria gonorrhoeae type IV pilus promotes resistance to hydrogen peroxide- and LL-37-mediated killing by modulating the availability of intracellular, labile iron

PLOS Pathogens
2022-06-17 | Journal article
DOI: 10.1371/journal.ppat.1010561
Contributors: Linda I. Hu; Mathieu Coureuil; Elizabeth A. Stohl; H Steven Seifert
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Crossref

Challenges and Controversies Concerning Neisseria gonorrhoeae-Neutrophil Interactions in Pathogenesis

mBio
2021-06-29 | Journal article
DOI: 10.1128/mBio.00721-21
Contributors: Alison K. Criss; Caroline A. Genco; Scott D. Gray-Owen; Ann E. Jerse; H Steven Seifert; Nancy E. Freitag
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Crossref

Discovery of a New Neisseria gonorrhoeae Type IV Pilus Assembly Factor, TfpC

mBio
2020-10-27 | Journal article
DOI: 10.1128/mBio.02528-20
Contributors: Linda I. Hu; Shaohui Yin; Egon A. Ozer; Lee Sewell; Saima Rehman; James A. Garnett; H Steven Seifert; Sheryl Justice
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Crossref

Discovery of a new Neisseria gonorrhoeae Type IV pilus assembly factor, TfpC

2020-09-26 | Other
DOI: 10.1101/2020.09.26.314724
Contributors: Linda I. Hu; Shaohui Yin; Egon A. Ozer; Lee Sewell; Saima Rehman; James A Garnett; H Steven Seifert
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Crossref

Altering the Neisseria gonorrhoeae pilE Guanine Quadruplex Loop Bases Affects Pilin Antigenic Variation

Biochemistry
2020-03-17 | Journal article
DOI: 10.1021/acs.biochem.9b01038
Contributors: Lauren L. Prister; Shaohui Yin; Laty A. Cahoon; H Steven Seifert
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Crossref

Transcriptional initiation of a small RNA, not R‐loop stability, dictates the frequency of pilin antigenic variation in Neisseria gonorrhoeae

Molecular Microbiology
2019-10 | Journal article
DOI: 10.1111/mmi.14356
Contributors: Lauren L. Prister; Egon A. Ozer; Laty A. Cahoon; Hank S. Seifert
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Crossref

PacBio Amplicon Sequencing Method To Measure Pilin Antigenic Variation Frequencies of Neisseria gonorrhoeae

mSphere
2019-10-30 | Journal article
DOI: 10.1128/mSphere.00562-19
Contributors: Egon A. Ozer; Lauren L. Prister; Shaohui Yin; Billy H. Ward; Stanimir Ivanov; H Steven Seifert; Vincent B. Young
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Crossref

A Double-Strand Break Does Not Promote Neisseria gonorrhoeae Pilin Antigenic Variation

Journal of Bacteriology
2019-07-15 | Journal article
DOI: 10.1128/JB.00256-19
Contributors: Lauren L. Prister; Jing Xu; H Steven Seifert; Michael J. Federle
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Crossref

Anti-psychotic drugs block meningococcal virulence

Nature Microbiology
2019-05-22 | Journal article
DOI: 10.1038/s41564-019-0467-9
Contributors: H Steven Seifert
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Crossref

R-loops modulate Trypanosome antigenic variation

PLOS Genetics
2018-12-13 | Journal article
DOI: 10.1371/journal.pgen.1007809
Contributors: Lauren L. Prister; Nancy Maizels; H. Steven Seifert
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Crossref

Analysis of Pilin Antigenic Variation in Neisseria meningitidis by Next-Generation Sequencing

Journal of Bacteriology
2018-11-15 | Journal article
DOI: 10.1128/JB.00465-18
Contributors: Jing Xu; H Steven Seifert; Victor J. DiRita
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Crossref

Neisseria gonorrhoeae Exposed to Sublethal Levels of Hydrogen Peroxide Mounts a Complex Transcriptional Response

mSystems
2018-10-30 | Journal article
DOI: 10.1128/msystems.00156-18
Contributors: Sarah J. Quillin; Adam J. Hockenberry; Michael C. Jewett; H Steven Seifert; Katrine L. Whiteson
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Crossref

The low‐molecular‐mass, penicillin‐binding proteins DacB and DacC combine to modify peptidoglycan cross‐linking and allow stable Type IV pilus expression in Neisseria gonorrhoeae

Molecular Microbiology
2018-07 | Journal article
DOI: 10.1111/mmi.13955
Contributors: Kyle P. Obergfell; Ryan E. Schaub; Lauren L. Priniski; Joseph P. Dillard; H Steven Seifert
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Crossref

Analyzing Neisseria gonorrhoeae Pilin Antigenic Variation Using 454 Sequencing Technology

Journal of Bacteriology
2016-09-15 | Journal article
DOI: 10.1128/JB.00330-16
Contributors: Ella Rotman; David M. Webber; H. Steven Seifert; V. J. DiRita
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Crossref

Seminal Plasma Promotes Neisseria gonorrhoeae Aggregation and Biofilm Formation

Journal of Bacteriology
2016-08-15 | Journal article
DOI: 10.1128/JB.00165-16
Contributors: Mark T. Anderson; Luke Byerly; Michael A. Apicella; H. Steven Seifert; A. Becker
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Crossref

The Pilin N-terminal Domain Maintains Neisseria gonorrhoeae Transformation Competence during Pilus Phase Variation

PLOS Genetics
2016-05-23 | Journal article
DOI: 10.1371/journal.pgen.1006069
Contributors: Kyle P. Obergfell; Lotte Søgaard-Andersen; H. Steven Seifert
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Crossref

The Gonococcal NlpD Protein Facilitates Cell Separation by Activating Peptidoglycan Cleavage by AmiC

Journal of Bacteriology
2016-02-15 | Journal article
DOI: 10.1128/JB.00540-15
Contributors: Elizabeth A. Stohl; Jonathan D. Lenz; Joseph P. Dillard; H. Steven Seifert; V. J. DiRita
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Crossref

Peer review (2 reviews for 2 publications/grants)

Review activity for ACS applied materials & interfaces. (1)
Review activity for Nature microbiology. (1)
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