Personal information

Other IDs

Scopus Author ID: 57226842922

Keywords

Biological engineering, Expansion microscopy

Countries

United States, Japan

Biography

Special Postdoctoral Researcher (2022-) at RIKEN, Japan
PI: Dr. Atsushi Miyawaki
Development of cell-internal recorders of biological signals

PhD (2014-2020) at MIT
PI: Dr. Edward S. Boyden
Major: Biological Engineering
Development of expansion microscopy

Undergraduate (2010-2014) at University of Pennsylvania
PI: Dr. Christopher Fang-Yen
Major: Bioengineering
Development of C. elegans multi-well imaging

See full list of publications at https://scholar.google.com/citations?hl=en&user=hi94SIgAAAAJ

Activities

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Education and qualifications (2)

Massachusetts Institute of Technology: Cambridge, MA, US

2014-09-01 to present | Doctor of Philosophy (PHD) (Biological Engineering)
Education
Source: Self-asserted source
Chih-Chieh (Jay) Yu

University of Pennsylvania: Philadelphia, PA, US

2010-09-01 to 2014-05-19 | Bachelor in Science and Engineering (BSE) (Bioengineering)
Education
Source: Self-asserted source
Chih-Chieh (Jay) Yu

Works (13)

Improved immunostaining of nanostructures and cells in human brain specimens through expansion-mediated protein decrowding

Science Translational Medicine
2024-01-31 | Journal article
DOI: 10.1126/scitranslmed.abo0049
Contributors: Pablo A. Valdes; Chih-Chieh (Jay) Yu; Jenna Aronson; Debarati Ghosh; Yongxin Zhao; Bobae An; Joshua D. Bernstock; Deepak Bhere; Michelle M. Felicella; Mariano S. Viapiano et al.
Source: check_circle
Crossref

A highly homogeneous polymer composed of tetrahedron-like monomers for high-isotropy expansion microscopy

Nature Nanotechnology
2021 | Journal article
DOI: 10.1038/s41565-021-00875-7
EID:

2-s2.0-85103424891

Part of ISSN: 17483395 17483387
Contributors: Gao, R.; Yu, C.-C.J.; Gao, L.; Piatkevich, K.D.; Neve, R.L.; Munro, J.B.; Upadhyayula, S.; Boyden, E.S.
Source: Self-asserted source
Chih-Chieh (Jay) Yu via Scopus - Elsevier

Expansion sequencing: Spatially precise in situ transcriptomics in intact biological systems

Science
2021 | Journal article
DOI: 10.1126/science.aax2656
EID:

2-s2.0-85100446979

Part of ISSN: 10959203 00368075
Contributors: Alon, S.; Goodwin, D.R.; Sinha, A.; Wassie, A.T.; Chen, F.; Daugharthy, E.R.; Bando, Y.; Kajita, A.; Xue, A.G.; Marrett, K. et al.
Source: Self-asserted source
Chih-Chieh (Jay) Yu via Scopus - Elsevier

Tetra-gel enables superior accuracy in combined super-resolution imaging and expansion microscopy

Scientific Reports
2021 | Journal article
DOI: 10.1038/s41598-021-96258-y
EID:

2-s2.0-85113212166

Part of ISSN: 20452322
Contributors: Lee, H.; Yu, C.-C.; Boyden, E.S.; Zhuang, X.; Kosuri, P.
Source: Self-asserted source
Chih-Chieh (Jay) Yu via Scopus - Elsevier

Precision Calcium Imaging of Dense Neural Populations via a Cell-Body-Targeted Calcium Indicator

Neuron
2020 | Journal article
DOI: 10.1016/j.neuron.2020.05.029
EID:

2-s2.0-85087664780

Part of ISSN: 10974199 08966273
Contributors: Shemesh, O.A.; Linghu, C.; Piatkevich, K.D.; Goodwin, D.; Celiker, O.T.; Gritton, H.J.; Romano, M.F.; Gao, R.; Yu, C.-C.J.; Tseng, H.-A. et al.
Source: Self-asserted source
Chih-Chieh (Jay) Yu via Scopus - Elsevier

Spatial Multiplexing of Fluorescent Reporters for Imaging Signaling Network Dynamics

Cell
2020 | Journal article
DOI: 10.1016/j.cell.2020.10.035
EID:

2-s2.0-85097457090

Part of ISSN: 10974172 00928674
Contributors: Linghu, C.; Johnson, S.L.; Valdes, P.A.; Shemesh, O.A.; Park, W.M.; Park, D.; Piatkevich, K.D.; Wassie, A.T.; Liu, Y.; An, B. et al.
Source: Self-asserted source
Chih-Chieh (Jay) Yu via Scopus - Elsevier

Expansion microscopy of C. elegans

eLife
2020-05-01 | Journal article
DOI: 10.7554/eLife.46249
Contributors: Chih-Chieh (Jay) Yu; Nicholas C Barry; Asmamaw T Wassie; Anubhav Sinha; Abhishek Bhattacharya; Shoh Asano; Chi Zhang; Fei Chen; Oliver Hobert; Miriam B Goodman et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

A highly homogeneous expansion microscopy polymer composed of tetrahedron-like monomers

2019-10-22 | Other
DOI: 10.1101/814111
Contributors: Ruixuan Gao; Chih-Chieh (Jay) Yu; Linyi Gao; Kiryl D Piatkevich; Rachael L Neve; Srigokul Upadhyayula; Edward S Boyden
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Longitudinal imaging of caenorhabditis elegans in a microfabricated device reveals variation in behavioral decline during aging

eLife
2017 | Journal article
DOI: 10.7554/eLife.26652
EID:

2-s2.0-85021426355

Part of ISSN: 2050084X
Contributors: Churgin, M.A.; Jung, S.-K.; Yu, C.-C.; Chen, X.; Raizen, D.M.; Fang-Yen, C.
Source: Self-asserted source
Chih-Chieh (Jay) Yu via Scopus - Elsevier

Protein-retention expansion microscopy of cells and tissues labeled using standard fluorescent proteins and antibodies

Nature Biotechnology
2016 | Journal article
DOI: 10.1038/nbt.3625
EID:

2-s2.0-84986593225

Part of ISSN: 15461696 10870156
Contributors: Tillberg, P.W.; Chen, F.; Piatkevich, K.D.; Zhao, Y.; Yu, C.-C.; English, B.P.; Gao, L.; Martorell, A.; Suk, H.-J.; Yoshida, F. et al.
Source: Self-asserted source
Chih-Chieh (Jay) Yu via Scopus - Elsevier

Multi-well imaging of development and behavior in Caenorhabditis elegans

Journal of Neuroscience Methods
2014 | Journal article
DOI: 10.1016/j.jneumeth.2013.11.026
EID:

2-s2.0-84890831575

Part of ISSN: 1872678X 01650270
Contributors: Yu, C.C.J.; Raizen, D.M.; Fang-Yen, C.
Source: Self-asserted source
Chih-Chieh (Jay) Yu via Scopus - Elsevier

Change in blood gelsolin concentration in response to physical exercise

Biology of Sport
2013 | Journal article
DOI: 10.5604/20831862.1059812
EID:

2-s2.0-84886913750

Part of ISSN: 0860021X 20831862
Contributors: Yu, C.-C.; Piotrowska, Z.-M.; Charmas, M.; Długolȩcka, B.; Baranowski, M.; Górski, J.; Bucki, R.
Source: Self-asserted source
Chih-Chieh (Jay) Yu via Scopus - Elsevier

The neuropeptide NLP-22 regulates a sleep-like state in Caenorhabditis elegans

Nature Communications
2013 | Journal article
DOI: 10.1038/ncomms3846
EID:

2-s2.0-84890159417

Part of ISSN: 20411723
Contributors: Nelson, M.D.; Trojanowski, N.F.; George-Raizen, J.B.; Smith, C.J.; Yu, C.-C.; Fang-Yen, C.; Raizen, D.M.
Source: Self-asserted source
Chih-Chieh (Jay) Yu via Scopus - Elsevier
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