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Works (49)

Analysis of AI foundation model features decodes the histopathologic landscape of HPV-positive head and neck squamous cell carcinomas

Oral Oncology
2025-04 | Journal article
Contributors: Hanna M. Hieromnimon; Anna Trzcinska; Frank T. Wen; Frederick M. Howard; James M. Dolezal; Emma Dyer; Sara Kochanny; Jefree J Schulte; Cindy Wang; Heather Chen et al.
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Generative adversarial networks accurately reconstruct pan-cancer histology from pathologic, genomic, and radiographic latent features

Science Advances
2024-11-15 | Journal article
Contributors: Frederick M. Howard; Hanna M. Hieromnimon; Siddhi Ramesh; James Dolezal; Sara Kochanny; Qianchen Zhang; Brad Feiger; Joseph Peterson; Cheng Fan; Charles M. Perou et al.
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Data from Reversal of lactate and PD-1-mediated macrophage immunosuppression controls growth of PTEN/p53-deficient prostate cancer

2024-09-16 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Rimpi Khurana; Brian Labadie; Taghreed Hirz; Shenglin Mei; Raisa Hasan; Jordan Shafran; Anne Kelley; Eva Apostolov et al.
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Data from Reversal of lactate and PD-1-mediated macrophage immunosuppression controls growth of PTEN/p53-deficient prostate cancer

2024-09-16 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Rimpi Khurana; Brian Labadie; Taghreed Hirz; Shenglin Mei; Raisa Hasan; Jordan Shafran; Anne Kelley; Eva Apostolov et al.
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Crossref

Supplementary Figures S1-S17 from Reversal of lactate and PD-1-mediated macrophage immunosuppression controls growth of PTEN/p53-deficient prostate cancer

2024-09-16 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Rimpi Khurana; Brian Labadie; Taghreed Hirz; Shenglin Mei; Raisa Hasan; Jordan Shafran; Anne Kelley; Eva Apostolov et al.
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Crossref

Supplementary Figures S1-S17 from Reversal of lactate and PD-1-mediated macrophage immunosuppression controls growth of PTEN/p53-deficient prostate cancer

2024-09-16 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Rimpi Khurana; Brian Labadie; Taghreed Hirz; Shenglin Mei; Raisa Hasan; Jordan Shafran; Anne Kelley; Eva Apostolov et al.
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Crossref

Supplementary Table S1 from Reversal of lactate and PD-1-mediated macrophage immunosuppression controls growth of PTEN/p53-deficient prostate cancer

2024-09-16 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Rimpi Khurana; Brian Labadie; Taghreed Hirz; Shenglin Mei; Raisa Hasan; Jordan Shafran; Anne Kelley; Eva Apostolov et al.
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Crossref

Supplementary Table S1 from Reversal of lactate and PD-1-mediated macrophage immunosuppression controls growth of PTEN/p53-deficient prostate cancer

2024-09-16 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Rimpi Khurana; Brian Labadie; Taghreed Hirz; Shenglin Mei; Raisa Hasan; Jordan Shafran; Anne Kelley; Eva Apostolov et al.
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Crossref

Data from Suppression of Tumor Cell Lactate-generating Signaling Pathways Eradicates Murine PTEN/p53-deficient Aggressive-variant Prostate Cancer via Macrophage Phagocytosis

2023-12-01 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Anne Kelley; Brian Labadie; Jordan Shafran; Srikrishnan Rameshbabu; Catherine Drovetsky; Kaela Bynoe; Ani Solanki; Erica Markiewicz et al.
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Crossref

Data from Suppression of Tumor Cell Lactate-generating Signaling Pathways Eradicates Murine PTEN/p53-deficient Aggressive-variant Prostate Cancer via Macrophage Phagocytosis

2023-12-01 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Anne Kelley; Brian Labadie; Jordan Shafran; Srikrishnan Rameshbabu; Catherine Drovetsky; Kaela Bynoe; Ani Solanki; Erica Markiewicz et al.
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Supplementary Figure 1 from Suppression of Tumor Cell Lactate-generating Signaling Pathways Eradicates Murine PTEN/p53-deficient Aggressive-variant Prostate Cancer via Macrophage Phagocytosis

2023-12-01 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Anne Kelley; Brian Labadie; Jordan Shafran; Srikrishnan Rameshbabu; Catherine Drovetsky; Kaela Bynoe; Ani Solanki; Erica Markiewicz et al.
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Supplementary Figure 1 from Suppression of Tumor Cell Lactate-generating Signaling Pathways Eradicates Murine PTEN/p53-deficient Aggressive-variant Prostate Cancer via Macrophage Phagocytosis

2023-12-01 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Anne Kelley; Brian Labadie; Jordan Shafran; Srikrishnan Rameshbabu; Catherine Drovetsky; Kaela Bynoe; Ani Solanki; Erica Markiewicz et al.
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Supplementary Figure 10 from Suppression of Tumor Cell Lactate-generating Signaling Pathways Eradicates Murine PTEN/p53-deficient Aggressive-variant Prostate Cancer via Macrophage Phagocytosis

2023-12-01 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Anne Kelley; Brian Labadie; Jordan Shafran; Srikrishnan Rameshbabu; Catherine Drovetsky; Kaela Bynoe; Ani Solanki; Erica Markiewicz et al.
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Supplementary Figure 10 from Suppression of Tumor Cell Lactate-generating Signaling Pathways Eradicates Murine PTEN/p53-deficient Aggressive-variant Prostate Cancer via Macrophage Phagocytosis

2023-12-01 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Anne Kelley; Brian Labadie; Jordan Shafran; Srikrishnan Rameshbabu; Catherine Drovetsky; Kaela Bynoe; Ani Solanki; Erica Markiewicz et al.
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Supplementary Figure 11 from Suppression of Tumor Cell Lactate-generating Signaling Pathways Eradicates Murine PTEN/p53-deficient Aggressive-variant Prostate Cancer via Macrophage Phagocytosis

2023-12-01 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Anne Kelley; Brian Labadie; Jordan Shafran; Srikrishnan Rameshbabu; Catherine Drovetsky; Kaela Bynoe; Ani Solanki; Erica Markiewicz et al.
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Supplementary Figure 11 from Suppression of Tumor Cell Lactate-generating Signaling Pathways Eradicates Murine PTEN/p53-deficient Aggressive-variant Prostate Cancer via Macrophage Phagocytosis

2023-12-01 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Anne Kelley; Brian Labadie; Jordan Shafran; Srikrishnan Rameshbabu; Catherine Drovetsky; Kaela Bynoe; Ani Solanki; Erica Markiewicz et al.
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Supplementary Figure 12 from Suppression of Tumor Cell Lactate-generating Signaling Pathways Eradicates Murine PTEN/p53-deficient Aggressive-variant Prostate Cancer via Macrophage Phagocytosis

2023-12-01 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Anne Kelley; Brian Labadie; Jordan Shafran; Srikrishnan Rameshbabu; Catherine Drovetsky; Kaela Bynoe; Ani Solanki; Erica Markiewicz et al.
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Supplementary Figure 12 from Suppression of Tumor Cell Lactate-generating Signaling Pathways Eradicates Murine PTEN/p53-deficient Aggressive-variant Prostate Cancer via Macrophage Phagocytosis

2023-12-01 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Anne Kelley; Brian Labadie; Jordan Shafran; Srikrishnan Rameshbabu; Catherine Drovetsky; Kaela Bynoe; Ani Solanki; Erica Markiewicz et al.
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Supplementary Figure 2 from Suppression of Tumor Cell Lactate-generating Signaling Pathways Eradicates Murine PTEN/p53-deficient Aggressive-variant Prostate Cancer via Macrophage Phagocytosis

2023-12-01 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Anne Kelley; Brian Labadie; Jordan Shafran; Srikrishnan Rameshbabu; Catherine Drovetsky; Kaela Bynoe; Ani Solanki; Erica Markiewicz et al.
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Supplementary Figure 2 from Suppression of Tumor Cell Lactate-generating Signaling Pathways Eradicates Murine PTEN/p53-deficient Aggressive-variant Prostate Cancer via Macrophage Phagocytosis

2023-12-01 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Anne Kelley; Brian Labadie; Jordan Shafran; Srikrishnan Rameshbabu; Catherine Drovetsky; Kaela Bynoe; Ani Solanki; Erica Markiewicz et al.
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Supplementary Figure 3 from Suppression of Tumor Cell Lactate-generating Signaling Pathways Eradicates Murine PTEN/p53-deficient Aggressive-variant Prostate Cancer via Macrophage Phagocytosis

2023-12-01 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Anne Kelley; Brian Labadie; Jordan Shafran; Srikrishnan Rameshbabu; Catherine Drovetsky; Kaela Bynoe; Ani Solanki; Erica Markiewicz et al.
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Supplementary Figure 3 from Suppression of Tumor Cell Lactate-generating Signaling Pathways Eradicates Murine PTEN/p53-deficient Aggressive-variant Prostate Cancer via Macrophage Phagocytosis

2023-12-01 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Anne Kelley; Brian Labadie; Jordan Shafran; Srikrishnan Rameshbabu; Catherine Drovetsky; Kaela Bynoe; Ani Solanki; Erica Markiewicz et al.
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Supplementary Figure 4 from Suppression of Tumor Cell Lactate-generating Signaling Pathways Eradicates Murine PTEN/p53-deficient Aggressive-variant Prostate Cancer via Macrophage Phagocytosis

2023-12-01 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Anne Kelley; Brian Labadie; Jordan Shafran; Srikrishnan Rameshbabu; Catherine Drovetsky; Kaela Bynoe; Ani Solanki; Erica Markiewicz et al.
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Supplementary Figure 4 from Suppression of Tumor Cell Lactate-generating Signaling Pathways Eradicates Murine PTEN/p53-deficient Aggressive-variant Prostate Cancer via Macrophage Phagocytosis

2023-12-01 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Anne Kelley; Brian Labadie; Jordan Shafran; Srikrishnan Rameshbabu; Catherine Drovetsky; Kaela Bynoe; Ani Solanki; Erica Markiewicz et al.
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Supplementary Figure 5 from Suppression of Tumor Cell Lactate-generating Signaling Pathways Eradicates Murine PTEN/p53-deficient Aggressive-variant Prostate Cancer via Macrophage Phagocytosis

2023-12-01 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Anne Kelley; Brian Labadie; Jordan Shafran; Srikrishnan Rameshbabu; Catherine Drovetsky; Kaela Bynoe; Ani Solanki; Erica Markiewicz et al.
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Supplementary Figure 5 from Suppression of Tumor Cell Lactate-generating Signaling Pathways Eradicates Murine PTEN/p53-deficient Aggressive-variant Prostate Cancer via Macrophage Phagocytosis

2023-12-01 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Anne Kelley; Brian Labadie; Jordan Shafran; Srikrishnan Rameshbabu; Catherine Drovetsky; Kaela Bynoe; Ani Solanki; Erica Markiewicz et al.
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Supplementary Figure 6 from Suppression of Tumor Cell Lactate-generating Signaling Pathways Eradicates Murine PTEN/p53-deficient Aggressive-variant Prostate Cancer via Macrophage Phagocytosis

2023-12-01 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Anne Kelley; Brian Labadie; Jordan Shafran; Srikrishnan Rameshbabu; Catherine Drovetsky; Kaela Bynoe; Ani Solanki; Erica Markiewicz et al.
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Supplementary Figure 6 from Suppression of Tumor Cell Lactate-generating Signaling Pathways Eradicates Murine PTEN/p53-deficient Aggressive-variant Prostate Cancer via Macrophage Phagocytosis

2023-12-01 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Anne Kelley; Brian Labadie; Jordan Shafran; Srikrishnan Rameshbabu; Catherine Drovetsky; Kaela Bynoe; Ani Solanki; Erica Markiewicz et al.
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Supplementary Figure 7 from Suppression of Tumor Cell Lactate-generating Signaling Pathways Eradicates Murine PTEN/p53-deficient Aggressive-variant Prostate Cancer via Macrophage Phagocytosis

2023-12-01 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Anne Kelley; Brian Labadie; Jordan Shafran; Srikrishnan Rameshbabu; Catherine Drovetsky; Kaela Bynoe; Ani Solanki; Erica Markiewicz et al.
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Supplementary Figure 7 from Suppression of Tumor Cell Lactate-generating Signaling Pathways Eradicates Murine PTEN/p53-deficient Aggressive-variant Prostate Cancer via Macrophage Phagocytosis

2023-12-01 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Anne Kelley; Brian Labadie; Jordan Shafran; Srikrishnan Rameshbabu; Catherine Drovetsky; Kaela Bynoe; Ani Solanki; Erica Markiewicz et al.
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Supplementary Figure 8 from Suppression of Tumor Cell Lactate-generating Signaling Pathways Eradicates Murine PTEN/p53-deficient Aggressive-variant Prostate Cancer via Macrophage Phagocytosis

2023-12-01 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Anne Kelley; Brian Labadie; Jordan Shafran; Srikrishnan Rameshbabu; Catherine Drovetsky; Kaela Bynoe; Ani Solanki; Erica Markiewicz et al.
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Supplementary Figure 8 from Suppression of Tumor Cell Lactate-generating Signaling Pathways Eradicates Murine PTEN/p53-deficient Aggressive-variant Prostate Cancer via Macrophage Phagocytosis

2023-12-01 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Anne Kelley; Brian Labadie; Jordan Shafran; Srikrishnan Rameshbabu; Catherine Drovetsky; Kaela Bynoe; Ani Solanki; Erica Markiewicz et al.
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Supplementary Figure 9 from Suppression of Tumor Cell Lactate-generating Signaling Pathways Eradicates Murine PTEN/p53-deficient Aggressive-variant Prostate Cancer via Macrophage Phagocytosis

2023-12-01 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Anne Kelley; Brian Labadie; Jordan Shafran; Srikrishnan Rameshbabu; Catherine Drovetsky; Kaela Bynoe; Ani Solanki; Erica Markiewicz et al.
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Supplementary Figure 9 from Suppression of Tumor Cell Lactate-generating Signaling Pathways Eradicates Murine PTEN/p53-deficient Aggressive-variant Prostate Cancer via Macrophage Phagocytosis

2023-12-01 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Anne Kelley; Brian Labadie; Jordan Shafran; Srikrishnan Rameshbabu; Catherine Drovetsky; Kaela Bynoe; Ani Solanki; Erica Markiewicz et al.
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Supplementary Table 1 from Suppression of Tumor Cell Lactate-generating Signaling Pathways Eradicates Murine PTEN/p53-deficient Aggressive-variant Prostate Cancer via Macrophage Phagocytosis

2023-12-01 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Anne Kelley; Brian Labadie; Jordan Shafran; Srikrishnan Rameshbabu; Catherine Drovetsky; Kaela Bynoe; Ani Solanki; Erica Markiewicz et al.
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Crossref

Supplementary Table 1 from Suppression of Tumor Cell Lactate-generating Signaling Pathways Eradicates Murine PTEN/p53-deficient Aggressive-variant Prostate Cancer via Macrophage Phagocytosis

2023-12-01 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Anne Kelley; Brian Labadie; Jordan Shafran; Srikrishnan Rameshbabu; Catherine Drovetsky; Kaela Bynoe; Ani Solanki; Erica Markiewicz et al.
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Suppression of Tumor Cell Lactate-generating Signaling Pathways Eradicates Murine PTEN/p53-deficient Aggressive-variant Prostate Cancer via Macrophage Phagocytosis

Clinical Cancer Research
2023-12-01 | Journal article
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Anne Kelley; Brian Labadie; Jordan Shafran; Srikrishnan Rameshbabu; Catherine Drovetsky; Kaela Bynoe; Ani Solanki; Erica Markiewicz et al.
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Crossref

Data from Reversal of Lactate and PD-1–mediated Macrophage Immunosuppression Controls Growth of PTEN/p53-deficient Prostate Cancer

2023-05-15 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Rimpi Khurana; Brian Labadie; Taghreed Hirz; Shenglin Mei; Raisa Hasan; Jordan Shafran; Anne Kelley; Eva Apostolov et al.
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Crossref

Reversal of Lactate and PD-1–mediated Macrophage Immunosuppression Controls Growth of PTEN/p53-deficient Prostate Cancer

Clinical Cancer Research
2023-05-15 | Journal article
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Rimpi Khurana; Brian Labadie; Taghreed Hirz; Shenglin Mei; Raisa Hasan; Jordan Shafran; Anne Kelley; Eva Apostolov et al.
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Crossref

Supplementary Figures S1-S17 from Reversal of Lactate and PD-1–mediated Macrophage Immunosuppression Controls Growth of PTEN/p53-deficient Prostate Cancer

2023-05-15 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Rimpi Khurana; Brian Labadie; Taghreed Hirz; Shenglin Mei; Raisa Hasan; Jordan Shafran; Anne Kelley; Eva Apostolov et al.
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Crossref

Supplementary Figures S1-S17 from Reversal of Lactate and PD-1–mediated Macrophage Immunosuppression Controls Growth of PTEN/p53-deficient Prostate Cancer

2023-05-15 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Rimpi Khurana; Brian Labadie; Taghreed Hirz; Shenglin Mei; Raisa Hasan; Jordan Shafran; Anne Kelley; Eva Apostolov et al.
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Crossref

Supplementary Table S1 from Reversal of Lactate and PD-1–mediated Macrophage Immunosuppression Controls Growth of PTEN/p53-deficient Prostate Cancer

2023-05-15 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Rimpi Khurana; Brian Labadie; Taghreed Hirz; Shenglin Mei; Raisa Hasan; Jordan Shafran; Anne Kelley; Eva Apostolov et al.
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Crossref

Supplementary Table S1 from Reversal of Lactate and PD-1–mediated Macrophage Immunosuppression Controls Growth of PTEN/p53-deficient Prostate Cancer

2023-05-15 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Rimpi Khurana; Brian Labadie; Taghreed Hirz; Shenglin Mei; Raisa Hasan; Jordan Shafran; Anne Kelley; Eva Apostolov et al.
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Crossref

Data from Reversal of Lactate and PD-1–mediated Macrophage Immunosuppression Controls Growth of PTEN/p53-deficient Prostate Cancer

2023-04-04 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Rimpi Khurana; Brian Labadie; Taghreed Hirz; Shenglin Mei; Raisa Hasan; Jordan Shafran; Anne Kelley; Eva Apostolov et al.
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Crossref

Supplementary Figures S1-S17 from Reversal of Lactate and PD-1–mediated Macrophage Immunosuppression Controls Growth of PTEN/p53-deficient Prostate Cancer

2023-04-04 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Rimpi Khurana; Brian Labadie; Taghreed Hirz; Shenglin Mei; Raisa Hasan; Jordan Shafran; Anne Kelley; Eva Apostolov et al.
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Crossref

Supplementary Figures S1-S17 from Reversal of Lactate and PD-1–mediated Macrophage Immunosuppression Controls Growth of PTEN/p53-deficient Prostate Cancer

2023-04-04 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Rimpi Khurana; Brian Labadie; Taghreed Hirz; Shenglin Mei; Raisa Hasan; Jordan Shafran; Anne Kelley; Eva Apostolov et al.
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Crossref

Supplementary Table S1 from Reversal of Lactate and PD-1–mediated Macrophage Immunosuppression Controls Growth of PTEN/p53-deficient Prostate Cancer

2023-04-04 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Rimpi Khurana; Brian Labadie; Taghreed Hirz; Shenglin Mei; Raisa Hasan; Jordan Shafran; Anne Kelley; Eva Apostolov et al.
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Crossref

Supplementary Table S1 from Reversal of Lactate and PD-1–mediated Macrophage Immunosuppression Controls Growth of PTEN/p53-deficient Prostate Cancer

2023-04-04 | Preprint
Contributors: Kiranj Chaudagar; Hanna M. Hieromnimon; Rimpi Khurana; Brian Labadie; Taghreed Hirz; Shenglin Mei; Raisa Hasan; Jordan Shafran; Anne Kelley; Eva Apostolov et al.
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Latent transcriptional programs reveal histology-encoded tumor features spanning tissue origins

2023-03-24 | Preprint
Contributors: Hanna M. Hieromnimon; James Dolezal; Kristina Doytcheva; Frederick M. Howard; Sara Kochanny; Zhenyu Zhang; Robert L. Grossman; Kevin Tanager; Cindy Wang; Jakob Nikolas Kather et al.
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