Personal information

depression; Nrf2 transcription factor; (R,S)-Sulforaphane; inflammatory; oxidative stress
Poland

Activities

Employment (1)

Institute of Medical Sciences, Medical College of Rzeszow University: Rzeszów, PL

(Department of Human Physiology )
Employment
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

Education and qualifications (3)

Maj Institute of Pharmacology, Polish Academy of Sciences : Krakow, PL

2015-10 to 2019-10 | Doctor of medical and health sciences (dyscypline - medical sciences)
Education
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

Institute of Applied Biotechnology and Basic Sciences, University of Rzeszow: Rzeszow, PL

2014-02 to 2015-07 | Master’s degree study (Molecular Biotechnology)
Education
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

Institute of Applied Biotechnology and Basic Sciences, University of Rzeszow: Rzeszow, PL

2010-10 to 2014-01 | engineer degree (Analytical biotechnology)
Education
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

Professional activities (4)

Polish Neuroscience Society: Warszawa, PL

2021-08 to present | regular membership
Membership
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

International Brain Research Organization: Paris, FR

2021-08 to present | member
Membership
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

Federation of European Neuroscience Societies: Brussels, BE

2021-08 to present | member
Membership
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

Polish Copernicus Society of Naturalists: Krakow, PL

2020-08 to present | member
Membership
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

Funding (1)

The role of (R,S)-Sulforaphane-induced activation of Nrf2 transcription factor in the regulation of depressive-like behavior in the olfactory bulbectomy model in mice.

Grant
National Research Centre (Krakow, PL)
GRANT_NUMBER:

2016/23/N/NZ4/01337

Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

Works (40)

Association of α-Klotho with regulation of Keap1/Nrf2/interleukin-1 pathway and AMPA receptor trafficking in the brain of suicide victims

Journal of Physiology and Pharmacology
2024 | Journal article
Contributors: Patrycja Pańczyszyn-Trzewik; Paulina Misztak ; Gabriel Nowak ; Magdalena Sowa-Kućma
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

Exploring the Pharmacological and Clinical Features of Lumateperone: A Promising Novel Antipsychotic

International Journal of Molecular Sciences
2024-12-11 | Journal article
Contributors: Magdalena Sowa-Kućma; Patrycja Pańczyszyn-Trzewik; Rafał R. Jaeschke
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Time-dependent dual mode of action of COX-2 inhibition on mouse serum corticosterone levels

Steroids
2024-07 | Journal article
Part of ISSN: 0039-128X
Contributors: Patrycja Pańczyszyn-Trzewik; Magdalena Sowa-Kućma; Paulina Misztak; Anna Tabecka-Lonczynska; Katarzyna Stachowicz
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

Repeated Sulforaphane Treatment Reverses Depressive-like Behavior and Exerts Antioxidant Effects in the Olfactory Bulbectomy Model in Mice

Pharmaceuticals
2024-06-11 | Journal article
Contributors: Patrycja Pańczyszyn-Trzewik; Katarzyna Stachowicz; Paulina Misztak; Gabriel Nowak; Magdalena Sowa-Kućma
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Cyclooxygenase-2 inhibition affects the ratio of GluN2A/GluN2B receptor subunits through interaction with mGluR5 in the mouse brain

Neuropeptides
2024-04 | Journal article
Part of ISSN: 0143-4179
Contributors: Katarzyna Stachowicz; Patrycja Pańczyszyn-Trzewik; Paulina Misztak; Szymon Rzeźniczek; Magdalena Sowa-Kućma
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

New Light on Prions: Putative Role of PrPc in Pathophysiology of Mood Disorders

International Journal of Molecular Sciences
2024-03-04 | Journal article
Contributors: Adrian Andrzej Chrobak; Patrycja Pańczyszyn-Trzewik; Patrycja Król; Magdalena Pawelec-Bąk; Dominika Dudek; Marcin Siwek
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

The Importance of α-Klotho in Depression and Cognitive Impairment and Its Connection to Glutamate Neurotransmission—An Up-to-Date Review

International Journal of Molecular Sciences
2023-10-17 | Journal article
Contributors: Patrycja Pańczyszyn-Trzewik; Ewelina Czechowska; Katarzyna Stachowicz; Magdalena Sowa-Kućma
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Changes in working memory induced by lipopolysaccharide administration in mice are associated with metabotropic glutamate receptors 5 and contrast with changes induced by cyclooxygenase-2: Involvement of postsynaptic density protein 95 and down syndrome cell adhesion molecule

Neuropeptides
2023-08 | Journal article
Part of ISSN: 0143-4179
Contributors: Katarzyna Stachowicz; Patrycja Pańczyszyn-Trzewik; Magdalena Sowa-Kućma; Paulina Misztak
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

Oxidative stress responses and their alterations in the Nrf2-NMDA receptor pathway in the brain of suicide victims.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society
2023-06-01 | Journal article
Contributors: Panczyszyn-Trzewik P; Misztak P; Opoka W; Nowak G; Sowa-Kucma M
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

Cyclooxygenase-2 inhibition affects the expression of down syndrome cell adhesion molecule via interaction with metabotropic glutamate receptor 5

Journal of Physiology and Pharmacology
2022 | Journal article
Contributors: Stachowicz K; Pańczyszyn-Trzewik P; Rzeźnikczek S; Sowa-Kućma M
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

Postsynaptic Proteins at Excitatory Synapses in the Brain—Relationship with Depressive Disorders

International Journal of Molecular Sciences
2022-09 | Journal article | Author
Contributors: Sylwia Samojedny; Ewelina Czechowska; Patrycja Pańczyszyn-Trzewik; Magdalena Sowa-Kucma
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Optogenetyka jako narzędzie w badaniach nad chorobą Alzheimera

Postępy biologii komórki, 2021/1; tom 48 (27-40)
2021 | Journal article
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

Antidepressant-like Effects of Combined Fluoxetine and Zinc Treatment in Mice Exposed to Chronic Restraint Stress Are Related to Modulation of Histone Deacetylase.

Molecules (Basel, Switzerland)
2021-12-21 | Journal article
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik
grade
Preferred source (of 3)‎

Upregulation of the mGlu5 receptor and COX-2 protein in the mouse brain after imipramine and NS398, searching for mechanisms of regulation

Neurochemistry International
2021-09 | Journal article
Part of ISSN: 0197-0186
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

OB-induced oxidative stress and inflammation in the frontal cortex and hippocampus of rats are associated with changes in NMDA and AMPA receptors trafficking

Virtual FENS Regional Meeting 2021
2021-08-25 | Conference abstract
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

Zinc deficiency-incudec depression-like behavior in rats is associated with changes in the synaptic distribution of AMPA/NMDA complexes in frontal cortex

Virtual FENS Regional Meeting 2021
2021-08-25 | Conference abstract
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

CZYNNIK TRANSKRYPCYJNY MeCP2 – KRYTYCZNY REGULATOR EPIGENETYCZNY W MÓZGU

Postępy Biologii Komórki
2020 | Journal article
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

ROLA CZYNNIKA Nrf2 I JEGO AKTYWATORÓW W PATOGENEZIE WYBRANYCH CHORÓB ZWIĄZANYCH Z DYSFUNKCJĄ UKŁADU NERWOWEGO

Postępy Biologii Komórki
2020 | Journal article
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

Behavioral consequences of co-administration of MTEP and the COX-2 inhibitor NS398 in mice. Part 2.

Neuroscience letters
2020-11-07 | Journal article
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

Epigenetic marks and their relationship with BDNF in the brain of suicide victims.

PloS one
2020-09-24 | Journal article
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

European Journal of Clinical and Experimental Medicine

Applicability of Cardiopulmonary Exercise Test
2019-12 | Journal article
Part of ISSN: 2544-2406
Part of ISSN: 2544-1361
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

A mind-brain-body dataset of MRI, EEG, cognition, emotion, and peripheral physiology in young and old adults.

Scientific data
2019-02-12 | Journal article
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

Alterations of Nrf2 nuclear factor are associated with inflammation and oxidative stress in chronic mild stress animal model of depression

European Neuropsychopharmacology
2017-10 | Conference abstract
Part of ISSN: 0924-977X
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

Chronic co-administration of mGluR5 antagonist (MTEP) with COX-2 inhibitor (NS398) affects DSCAM expression in prefrontal cortex and hippocampus in C57Bl/6J mice

European Neuropsychopharmacology
2017-10 | Conference abstract
Part of ISSN: 0924-977X
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

NS-398 potentiates the antidepressant-like effect of MTEP in mice: involvement of pro-inflammatory cytokine pathways in the brain

European Neuropsychopharmacology
2017-10 | Conference abstract
Part of ISSN: 0924-977X
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

The effects of co-administration MTEP antagonist and NS-398 on synaptic plasticity in the frontal cortex and hippocampus of mice

European Neuropsychopharmacology
2017-10 | Conference abstract
Part of ISSN: 0924-977X
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

Histone deacetylases (HDACs) as therapeutic target for depressive disorders.

Pharmacological reports : PR
2017-08-12 | Journal article
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

Co-administration of COX-2 inhibitor NS-398 enhances antidepressant effect of mGluR5 antagonist MTEP in mice

European Neuropsychopharmacology
2017-03 | Conference abstract
Part of ISSN: 0924-977X
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

Repeated co-treatment with antidepressants and risperidone increases BDNF mRNA and protein levels in rats.

Pharmacological reports : PR
2017-03-04 | Journal article
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

Vortioxetine: A review of the pharmacology and clinical profile of the novel antidepressant.

Pharmacological reports : PR
2017-02-01 | Journal article
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

Chronic mild stress-induced alterations in ΔFosB protein and histone H3 acetylation in the frontal cortex of rats

European Neuropsychopharmacology
2016-10 | Conference abstract
Part of ISSN: 0924-977X
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

Epigenetic dysregulation in the frontal cortex of suicide victims

European Neuropsychopharmacology
2016-10 | Conference paper
Part of ISSN: 0924-977X
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

Oxidative stress in the brain of suicide victims is associated with alterations in AMPA receptor subunits

European Neuropsychopharmacology
2016-10 | Conference abstract
Part of ISSN: 0924-977X
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

Lurasidone: The 2016 update on the pharmacology, efficacy and safety profile.

Pharmacological reports : PR
2016-04-22 | Journal article
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

P.1.011 Changes in miR-212/132 expression in the hippocampus of rats subjected to olfactory bulbectomy

European Neuropsychopharmacology
2016-03 | Conference abstract
Part of ISSN: 0924-977X
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

Alterations in Nrf2 Protein Level in The Frontal Cortex of Suicide Victims and Depressed Subjects are Associated with Nf κB(P65) Changes - Evidence From Post Mortem Brain Study

12th Neuronus 2022 Neuroscience Forum
Conference paper
Contributors: Patrycja Pańczyszyn-Trzewik ; Ewelina Sujkowska; Sylwia Samojedny ; Magdalena Sowa-Kućma
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

Antidepressant-like effect of (R,S)- sulforaphane (an activator of Nrf2) in the olfactory bulbectomy model in mice

European Neuropsychopharmacology
Conference abstract
Part of ISSN: 0924-977X
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

Chronic co-treatment of NS398 (COX-2 inhibitor) with MTEP changes strategy of mice in Barnes Maze, through membrane resistance variation

European Neuropsychopharmacology
Conference abstract
Part of ISSN: 0924-977X
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

effect of co-administration of zinc and fluoxetine in the chronic restraint stress model of depression in mice

European Neuropsychopharmacology
Conference abstract
Part of ISSN: 0924-977X
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik

Increased oxidative stress in the frontal cortex of suicide victims is associated with changes in NMDA receptor, AMPK activity and magnesium level

European Neuropsychopharmacology
Conference abstract
Part of ISSN: 0924-977X
Source: Self-asserted source
Patrycja Pańczyszyn-Trzewik