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Scopus Author ID: 9733747600
SciProfiles: 2391919

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Employment (1)

Evotec International GmbH: Gottingen, Niedersachsen, DE

2022-08-01 to present | Senior Research Scientist (Cell Therapies & Genome Engineering)
Employment
Source: Self-asserted source
Philip Hublitz

Education and qualifications (1)

University of Oxford: Oxford, Oxfordshire, GB

2014-09-01 to 2022-06-30 | Dr. (WIMM, Genome Engineering)
Education
Source: Self-asserted source
Philip Hublitz

Professional activities (2)

MDPI AG: Basel, BS, CH

Editor (Methods and Protocols)
Invited position
Source: Self-asserted source
Philip Hublitz

ISTT: Oxford, GB

2015 to present
Membership
Source: Self-asserted source
Philip Hublitz

Works (32)

Methods and Protocols—Aims and Scope Update

Methods and Protocols
2023-11-17 | Journal article
DOI: 10.3390/mps6060111
Contributors: Fernando Albericio; Philip Hublitz
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SARS-CoV-2 mutations affect antigen processing by the proteasome to alter CD8+ T cell responses

Heliyon
2023-10 | Journal article
DOI: 10.1016/j.heliyon.2023.e20076
Contributors: Dannielle Wellington; Zixi Yin; Zhanru Yu; Raphael Heilig; Simon Davis; Roman Fischer; Suet Ling Felce; Elie Antoun; Philip Hublitz; Ryan Beveridge et al.
Source: check_circle
Crossref

An immunodominant NP<sub>105–113</sub>-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease

Nature Immunology
2022 | Journal article
DOI: 10.1038/s41590-021-01084-z
EID:

2-s2.0-85120634509

Part of ISSN: 15292916 15292908
Contributors: Peng, Y.; Felce, S.L.; Dong, D.; Penkava, F.; Mentzer, A.J.; Yao, X.; Liu, G.; Yin, Z.; Chen, J.-L.; Lu, Y. et al.
Source: Self-asserted source
Philip Hublitz via Scopus - Elsevier

Diffusion and interaction dynamics of the cytosolic peroxisomal import receptor PEX5

Biophysical Reports
2022 | Journal article
DOI: 10.1016/j.bpr.2022.100055
EID:

2-s2.0-85133698766

Part of ISSN: 26670747
Contributors: Galiani, S.; Reglinski, K.; Carravilla, P.; Barbotin, A.; Urbančič, I.; Ott, J.; Sehr, J.; Sezgin, E.; Schneider, F.; Waithe, D. et al.
Source: Self-asserted source
Philip Hublitz via Scopus - Elsevier

SARS-CoV-2 mutations affect proteasome processing to alter CD8<sup>+</sup> T cell responses

bioRxiv
2022 | Other
DOI: 10.1101/2022.04.08.487623
EID:

2-s2.0-85131190469

Part of ISSN: 26928205
Contributors: Wellington, D.; Yin, Z.; Yu, Z.; Heilig, R.; Davis, S.; Fischer, R.; Felce, S.L.; Hublitz, P.; Beveridge, R.; Dong, D. et al.
Source: Self-asserted source
Philip Hublitz via Scopus - Elsevier

Dual RNA sequencing reveals dendritic cell reprogramming in response to typhoidal Salmonella invasion

Communications Biology
2022-02-04 | Journal article
DOI: 10.1038/s42003-022-03038-z
Contributors: Anna Aulicino; Agne Antanaviciute; Joe Frost; Ana Sousa Geros; Esther Mellado; Moustafa Attar; Marta Jagielowicz; Philip Hublitz; Julia Sinz; Lorena Preciado-Llanes et al.
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A FOXN1 mutation competitively displaces wild-type FOXN1 from higher order nuclear condensates to cause immunodeficiency

bioRxiv
2021 | Other
DOI: 10.1101/2021.03.28.437237
EID:

2-s2.0-85105676709

Part of ISSN: 26928205
Contributors: Rota, I.A.; Handel, A.E.; Klein, F.; Maio, S.; Dhalla, F.; Deadman, M.E.; Cheuk, S.; Newman, J.A.; Michaels, Y.S.; Zuklys, S. et al.
Source: Self-asserted source
Philip Hublitz via Scopus - Elsevier

Diffusion and interaction dynamics of the cytosolic peroxisomal import receptor PEX5

bioRxiv
2021 | Other
DOI: 10.1101/2021.05.25.445571
EID:

2-s2.0-85108396857

Part of ISSN: 26928205
Contributors: Galiani, S.; Reglinski, K.; Carravilla, P.; Barbotin, A.; Urbančič, I.; Ott, J.; Sehr, J.; Sezgin, E.; Schneider, F.; Waithe, D. et al.
Source: Self-asserted source
Philip Hublitz via Scopus - Elsevier

FOXN1 forms higher-order nuclear condensates displaced by mutations causing immunodeficiency

Science Advances
2021 | Journal article
DOI: 10.1126/sciadv.abj9247
EID:

2-s2.0-85120704294

Part of ISSN: 23752548
Contributors: Rota, I.A.; Handel, A.E.; Maio, S.; Klein, F.; Dhalla, F.; Deadman, M.E.; Cheuk, S.; Newman, J.A.; Michaels, Y.S.; Zuklys, S. et al.
Source: Self-asserted source
Philip Hublitz via Scopus - Elsevier

Immunodominant NP105-113-B*0702 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease

ResearchSquare
2021 | Other
DOI: 10.21203/rs.3.rs-734011
EID:

2-s2.0-85132382147
Contributors: Dong, T.; Ogg, G.; Peng, Y.-C.; Felce, S.; Dong, D.; Penkava, F.; Mentzer, A.; Lao, X.; Liu, G.; Yin, Z. et al.
Source: Self-asserted source
Philip Hublitz via Scopus - Elsevier

Rapid emergence of chronic lymphocytic leukemia during JAK2 inhibitor therapy in a patient with myelofibrosis

HemaSphere
2020 | Journal article
DOI: 10.1097/HS9.0000000000000356
EID:

2-s2.0-85093965070

Part of ISSN: 25729241
Contributors: Sousos, N.; Buck, G.; Rodriguez-Meira, A.; Norfo, R.; Hamblin, A.; Pezzella, F.; Davies, J.; Hublitz, P.; Psaila, B.; Mead, A.J.
Source: Self-asserted source
Philip Hublitz via Scopus - Elsevier

Unexpectedly High Levels of Inverted Re-Insertions Using Paired sgRNAs for Genomic Deletions

Methods and Protocols
2020-07-29 | Journal article
DOI: 10.3390/mps3030053
Contributors: Joseph Blayney; Evangeline Foster; Marta Jagielowicz; Mira Kreuzer; Matteo Morotti; Katharina Reglinski; Julie Xiao; Philip Hublitz
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RIG-I Plays a Dominant Role in the Induction of Transcriptional Changes in Zika Virus-Infected Cells, which Protect from Virus-Induced Cell Death

Cells
2020-06-16 | Journal article
DOI: 10.3390/cells9061476
Contributors: Mirjam Schilling; Anne Bridgeman; Nicki Gray; Jonny Hertzog; Philip Hublitz; Alain Kohl; Jan Rehwinkel
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An integrated platform to systematically identify causal variants and genes for polygenic human traits

bioRxiv
2019 | Other
DOI: 10.1101/813618
EID:

2-s2.0-85095477227

Part of ISSN: 26928205
Contributors: Downes, D.J.; Schwessinger, R.; Hill, S.J.; Nussbaum, L.; Scott, C.; Gosden, M.E.; Hirschfeld, P.P.; Telenius, J.M.; Eijsbouts, C.Q.; McGowan, S.J. et al.
Source: Self-asserted source
Philip Hublitz via Scopus - Elsevier

Colonic epithelial cell diversity in health and inflammatory bowel disease

Nature
2019 | Journal article
DOI: 10.1038/s41586-019-0992-y
EID:

2-s2.0-85062586978

Part of ISSN: 14764687 00280836
Contributors: Parikh, K.; Antanaviciute, A.; Fawkner-Corbett, D.; Jagielowicz, M.; Aulicino, A.; Lagerholm, C.; Davis, S.; Kinchen, J.; Chen, H.H.; Alham, N.K. et al.
Source: Self-asserted source
Philip Hublitz via Scopus - Elsevier

Microhomologies are prevalent at Cas9-induced larger deletions

Nucleic Acids Research
2019 | Journal article
DOI: 10.1093/nar/gkz459
EID:

2-s2.0-85071708334

Part of ISSN: 13624962 03051048
Contributors: Owens, D.D.G.; Caulder, A.; Frontera, V.; Harman, J.R.; Allan, A.J.; Bucakci, A.; Greder, L.; Codner, G.F.; Hublitz, P.; McHugh, P.J. et al.
Source: Self-asserted source
Philip Hublitz via Scopus - Elsevier

Mouse model of the human serotonin transporter-linked polymorphic region

Mammalian Genome
2019 | Journal article
DOI: 10.1007/s00335-019-09815-2
EID:

2-s2.0-85074665384

Part of ISSN: 14321777 09388990
Contributors: Piszczek, L.; Memoli, S.; Raggioli, A.; Viosca, J.; Rientjes, J.; Hublitz, P.; Czaban, W.; Wyrzykowska, A.; Gross, C.
Source: Self-asserted source
Philip Hublitz via Scopus - Elsevier

Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence

Molecular Cell
2019 | Journal article
DOI: 10.1016/j.molcel.2019.08.005
EID:

2-s2.0-85072198754

Part of ISSN: 10974164 10972765
Contributors: Zhang, H.; Alsaleh, G.; Feltham, J.; Sun, Y.; Napolitano, G.; Riffelmacher, T.; Charles, P.; Frau, L.; Hublitz, P.; Yu, Z. et al.
Source: Self-asserted source
Philip Hublitz via Scopus - Elsevier

Infection with a Brazilian isolate of Zika virus generates RIG-I stimulatory RNA and the viral NS5 protein blocks type I IFN induction and signaling

European Journal of Immunology
2018 | Journal article
DOI: 10.1002/eji.201847483
EID:

2-s2.0-85044844141

Part of ISSN: 15214141 00142980
Contributors: Hertzog, J.; Dias Junior, A.G.; Rigby, R.E.; Donald, C.L.; Mayer, A.; Sezgin, E.; Song, C.; Jin, B.; Hublitz, P.; Eggeling, C. et al.
Source: Self-asserted source
Philip Hublitz via Scopus - Elsevier

Lack of Truncated IFITM3 Transcripts in Cells Homozygous for the rs12252-C Variant That is Associated with Severe Influenza Infection

Journal of Infectious Diseases
2018 | Journal article
DOI: 10.1093/infdis/jix512
EID:

2-s2.0-85040590942

Part of ISSN: 15376613 00221899
Contributors: Makvandi-Nejad, S.; Laurenson-Schafer, H.; Wang, L.; Wellington, D.; Zhao, Y.; Jin, B.; Qin, L.; Kite, K.; Moghadam, H.K.; Song, C. et al.
Source: Self-asserted source
Philip Hublitz via Scopus - Elsevier

SCL/TAL1 cooperates with Polycomb RYBP-PRC1 to suppress alternative lineages in blood-fated cells

Nature Communications
2018-12-18 | Journal article
DOI: 10.1038/s41467-018-07787-6
Contributors: Hedia Chagraoui; Maiken S. Kristiansen; Juan Pablo Ruiz; Ana Serra-Barros; Johanna Richter; Elisa Hall-Ponselé; Nicki Gray; Dominic Waithe; Kevin Clark; Philip Hublitz et al.
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Genetic abrogation of immune checkpoints in antigen-specific cytotoxic T-lymphocyte as a potential alternative to blockade immunotherapy

Scientific Reports
2018-04-03 | Journal article
DOI: 10.1038/s41598-018-23803-7
Contributors: Chi Zhang; Yanchun Peng; Philip Hublitz; Haokang Zhang; Tao Dong
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Autophagy-Dependent Generation of Free Fatty Acids Is Critical for Normal Neutrophil Differentiation

Immunity
2017 | Journal article
DOI: 10.1016/j.immuni.2017.08.005
EID:

2-s2.0-85029187945

Part of ISSN: 10974180 10747613
Contributors: Riffelmacher, T.; Clarke, A.; Richter, F.C.; Stranks, A.; Pandey, S.; Danielli, S.; Hublitz, P.; Yu, Z.; Johnson, E.; Schwerd, T. et al.
Source: Self-asserted source
Philip Hublitz via Scopus - Elsevier

Editing an α-globin enhancer in primary human hematopoietic stem cells as a treatment for β-Thalassemia

Nature Communications
2017 | Journal article
DOI: 10.1038/s41467-017-00479-7
EID:

2-s2.0-85028745539

Part of ISSN: 20411723
Contributors: Mettananda, S.; Fisher, C.A.; Hay, D.; Badat, M.; Quek, L.; Clark, K.; Hublitz, P.; Downes, D.; Kerry, J.; Gosden, M. et al.
Source: Self-asserted source
Philip Hublitz via Scopus - Elsevier

The K<sup>+</sup> channel GIRK2 is both necessary and sufficient for peripheral opioid-mediated analgesia

EMBO Molecular Medicine
2013 | Journal article
DOI: 10.1002/emmm.201201980
EID:

2-s2.0-84881535160

Part of ISSN: 17574676 17574684
Contributors: Nockemann, D.; Rouault, M.; Labuz, D.; Hublitz, P.; Mcknelly, K.; Reis, F.C.; Stein, C.; Heppenstall, P.A.
Source: Self-asserted source
Philip Hublitz via Scopus - Elsevier

Tubulin acetyltransferase α TAT1 destabilizes microtubules independently of its acetylation activity

Molecular and Cellular Biology
2013 | Journal article
DOI: 10.1128/MCB.01044-12
EID:

2-s2.0-84874709998

Part of ISSN: 02707306 10985549
Contributors: Kalebic, N.; Martinez, C.; Perlas, E.; Hublitz, P.; Bilbao-Cortes, D.; Fiedorczuk, K.; Andolfo, A.; Heppenstall, P.A.
Source: Self-asserted source
Philip Hublitz via Scopus - Elsevier

Generation and characterization of an Advillin-Cre driver mouse line

Molecular Pain
2011 | Journal article
DOI: 10.1186/1744-8069-7-66
EID:

2-s2.0-80052573470

Part of ISSN: 17448069
Contributors: Zurborg, S.; Piszczek, A.; Martínez, C.; Hublitz, P.; Al Banchaabouchi, M.; Moreira, P.; Perlas, E.; Heppenstall, P.A.
Source: Self-asserted source
Philip Hublitz via Scopus - Elsevier

Mechanisms of transcriptional repression by histone lysine methylation

International Journal of Developmental Biology
2009 | Journal article
DOI: 10.1387/ijdb.082717ph
EID:

2-s2.0-70349335528

Part of ISSN: 02146282
Contributors: Hublitz, P.; Albert, M.; Peters, A.H.F.M.
Source: Self-asserted source
Philip Hublitz via Scopus - Elsevier

NIR is a novel INHAT repressor that modulates the transcriptional activity of p53

Genes and Development
2005 | Journal article
DOI: 10.1101/gad.351205
EID:

2-s2.0-28444474846

Part of ISSN: 08909369 15495477
Contributors: Hublitz, P.; Kunowska, N.; Mayer, U.P.; Müller, J.M.; Heyne, K.; Yin, N.; Fritzsche, C.; Poli, C.; Miguet, L.; Schupp, I.W. et al.
Source: Self-asserted source
Philip Hublitz via Scopus - Elsevier

Molecular cloning of the Matrix Gla Protein gene from Xenopus laevis: Functional analysis of the promoter identifies a calcium sensitive region required for basal activity

European Journal of Biochemistry
2002 | Journal article
DOI: 10.1046/j.1432-1033.2002.02846.x
EID:

2-s2.0-85047699749

Part of ISSN: 00142956
Contributors: ConceiçãO, N.; Henriques, N.M.; Ohresser, M.C.P.; Hublitz, P.; SchüLe, R.; Cancela, M.L.
Source: Self-asserted source
Philip Hublitz via Scopus - Elsevier

The LIM-only coactivator FHL2 modulates WT1 transcriptional activity during gonadal differentiation

Biochimica et Biophysica Acta - Gene Structure and Expression
2002 | Journal article
DOI: 10.1016/S0167-4781(02)00414-1
EID:

2-s2.0-0037136244

Part of ISSN: 01674781
Contributors: Du, X.; Hublitz, P.; Günther, T.; Wilhelm, D.; Englert, C.; Schüle, R.
Source: Self-asserted source
Philip Hublitz via Scopus - Elsevier

Characterization of the DNA-binding and dimerization properties of the nuclear orphan receptor germ cell nuclear factor

Molecular and Cellular Biology
1999 | Journal article
DOI: 10.1128/MCB.19.1.690
EID:

2-s2.0-0032908351

Part of ISSN: 02707306
Contributors: Greschik, H.; Wurtz, J.-M.; Hublitz, P.; Köhler, F.; Moras, D.; Schüle, R.
Source: Self-asserted source
Philip Hublitz via Scopus - Elsevier

Peer review (5 reviews for 5 publications/grants)

Review activity for Communications biology. (1)
Review activity for Current issues in molecular biology. (1)
Review activity for European journal of human genetics (1)
Review activity for International journal of molecular sciences. (1)
Review activity for Microorganisms. (1)
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