Personal information

Biography

Pr APARICIO Thomas (MD-PHD)
Birth date : 25/10/67

Service de Gastroentérologie et Oncologie Digestive
Hôpital Saint Louis
1, avenue Claude Vellefaux, 75010 Paris
France

Tel : 33 1 42 49 95 97, Fax : 33 1 42 49 91 68
e-mail : thomas.aparicio@aphp.fr
N° ordre des médecins : 75/85850

Professional position
2016-.....: Professor in Gastroenterology (Saint Louis Hospital, Paris)
2016-....: Member of the research unit U1160, team "Intestinale immunity in inflammation and cancers" (Saint Louis)
2009- 2016 : Professor in Gastroenterology (Avicenne Hospital, Bobigny).
2003-2009 : Hepato-Gastroenterology and Digestive Oncology Department (Bichat Hospital, Paris). Manager of the Digestive Oncology unit.
2001-2003 : Laboratory Research in INSERM Unité U410 (Faculté, Xavier Bichat, Paris). Purpose : Leptin and colon carcinogenesis
1998-2001 : Senior Resident in Hepato-Gastroenterology (Bichat Hospital, Paris)
1997-1998 : Junior Resident in Institut Gustave Roussy (Villejuif)
1996-1997 : Laboratory Research in INSERM Unité 10 (Faculté, Xavier Bichat, Paris) Purpose : metalloprotease and colon carcinogenesis
1992-1996 : Medical Felloship, of medecin in Paris.
1985-1991 : Medical study, U.F.R. Broussais - Hôtel Dieu - PARIS VI.

Academic Qualifications
2006 : Habilitation to research leading, Paris VII
2005 : Doctorat ès Sciences, Paris VII
1998 : Cancerology qualification
1997 : Hepato-Gastroenterology qualification
1997 : Medical Doctorat

RELEVANT EXPERIENCE
Secretary of the Scientific Council of the Fédération Francophone de Cancérologie Digestive (FFCD) 2006-2011. General secretary of the FFCD since 2011.

Activities

Works (22)

Results of complete cytoreductive strategy in patients with peritoneal metastases of colorectal origin with or without extraperitoneal metastases: A bicentric analysis

European Journal of Surgical Oncology
2025-01 | Journal article
Contributors: Isabelle Sourrouille; Clément Pastier; Maximilliano Gelli; Léonor Benhaïm; Pierre Cattan; Michel Ducreux; Thomas Aparicio; Diane Goéré
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Crossref

Trifluridine/tipiracil + oxaliplatin ± nivolumab vs FOLFOX ± nivolumab in HER2 negative advanced oesogastric adenocarcinoma: The PRODIGE73-UCGI40-LOGICAN trial

Digestive and Liver Disease
2024-08 | Journal article
Contributors: Damien Botsen; Sylvie Chabaud; Hervé Perrier; Hanifa Ammarguellat; Véronique Jestin-Le-Tallec; Jonathan Olesinski; Clémence Toullec; Thomas Aparicio; Meher Ben Abdelghani; Christophe Borg et al.
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Crossref

Genomic profiling of small bowel adenocarcinoma: a pooled analysis from 3 databases

British Journal of Cancer
2024-07-27 | Journal article
Contributors: Thomas Aparicio; Julie Henriques; Magali Svrcek; Aziz Zaanan; Sylvain Manfredi; Andrea Casadei-Gardini; David Tougeron; Jean-Marc Gornet; Marine Jary; Eric Terrebonne et al.
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Crossref

How to Balance Prognostic Factors in Controlled Phase II Trials: Stratified Permuted Block Randomization or Minimization? An Analysis of Clinical Trials in Digestive Oncology

Current Oncology
2024-06 | Journal article | Author
Contributors: Elodie Martin; Karine Le Malicot; Catherine GUERIN-CHARBONNEL; François Bocquet; Olivier BOUCHE; Anthony Turpin; Thomas APARICIO; Jean-Louis Legoux; Laetitia Dahan; Julien Taieb et al.
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Multidisciplinary Digital Publishing Institute
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Preferred source (of 2)‎

First-Line LV5FU2 with or without Aflibercept in Patients with Non-Resectable Metastatic Colorectal Cancer: A Randomized Phase II Trial (PRODIGE 25-FFCD-FOLFA)

Cancers
2024-04-16 | Journal article
Contributors: Jean-Louis Legoux; Roger Faroux; Nicolas Barrière; Karine Le Malicot; David Tougeron; Véronique Lorgis; Véronique Guerin-Meyer; Vincent Bourgeois; David Malka; Thomas Aparicio et al.
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Crossref
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Preferred source (of 2)‎

Management of esogastric cancer in older patients

Therapeutic Advances in Medical Oncology
2024-01 | Journal article
Contributors: Thomas Aparicio; Anna Carteaux-Taieb; Amélie Arégui; Janina Estrada; Geoffroy Beraud-Chaulet; Virginie Fossey-Diaz; Pascal Hammel; Pierre Cattan
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Crossref

Molecular profiling of anal Paget’s disease and underlying anal adenocarcinoma highlights their common origin

EJC Skin Cancer
2023 | Journal article
Contributors: Yaëlle Bellahsen-Harrar; Marie Boisson; Baptiste Louveau; Barouyr Baroudjian; Thomas Aparicio; Valentine Ferré; Yann Parc; Aurélie Sadoux; Fanélie Jouenne; Maxime Battistella et al.
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Crossref

Time to recurrence and its relation to survival after recurrence in patients resected for stage III colon cancer

European Journal of Cancer
2023-11 | Journal article
Contributors: Cosimo Rasola; Pierre Laurent-Puig; Thierry André; Antoine Falcoz; Come Lepage; Thomas Aparicio; Olivier Bouché; Astrid Lievre; Laurent Mineur; Jaafar Bennouna et al.
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Crossref

Safety of FOLFIRI + Durvalumab +/− Tremelimumab in Second Line of Patients with Advanced Gastric Cancer: A Safety Run-In from the Randomized Phase II Study DURIGAST PRODIGE 59

Biomedicines
2022-05-23 | Journal article
Contributors: Camille Evrard; Thomas Aparicio; Emilie Soularue; Karine Le Malicot; Jérôme Desramé; Damien Botsen; Farid El Hajbi; Daniel Gonzalez; Come Lepage; Olivier Bouché et al.
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Crossref
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Preferred source (of 2)‎

Epidemiology, Risk Factors and Diagnosis of Small Bowel Adenocarcinoma

Cancers
2022-05-02 | Journal article
Contributors: Thomas Aparicio; Atanas Pachev; Pierre Laurent-Puig; Magali Svrcek
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Crossref
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Preferred source (of 2)‎

Heterogeneity of Mismatch Repair Status and Microsatellite Instability between Primary Tumour and Metastasis and Its Implications for Immunotherapy in Colorectal Cancers

International Journal of Molecular Sciences
2022-04-17 | Journal article
Contributors: Camille Evrard; Stéphane Messina; David Sefrioui; Éric Frouin; Marie-Luce Auriault; Romain Chautard; Aziz Zaanan; Marion Jaffrelot; Christelle De La Fouchardière; Thomas Aparicio et al.
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Crossref
grade
Preferred source (of 2)‎

Overall Survival and Prognostic Factors among Older Patients with Metastatic Pancreatic Cancer: A Retrospective Analysis Using a Hospital Database

Cancers
2022-02-22 | Journal article
Contributors: Catherine Conti; Frédéric Pamoukdjian; Thomas Aparicio; Soraya Mebarki; Johanne Poisson; Gilles Manceau; Julien Taieb; Bastien Rance; Sandrine Katsahian; Anaïs Charles-Nelson et al.
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Crossref
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Preferred source (of 2)‎

The Pre-Operative GRADE Score Is Associated with 5-Year Survival among Older Patients with Cancer Undergoing Surgery

Cancers
2021-12-27 | Journal article
Contributors: Philippe Wind; Zoe ap Thomas; Marie Laurent; Thomas Aparicio; Matthieu Siebert; Etienne Audureau; Elena Paillaud; Guilhem Bousquet; Frédéric Pamoukdjian
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Crossref
grade
Preferred source (of 2)‎

Predictive factors of severe early treatment-related toxicity in patients receiving first-line treatment for metastatic colorectal cancer: Pooled analysis of 2190 patients enrolled in Fédération Francophone de Cancérologie Digestive (FFCD) trials

European Journal of Cancer
2021-08 | Journal article
Contributors: Clémence Breton; Thomas Aparicio; Karine Le Malicot; Michel Ducreux; Thierry Lecomte; Jean-Baptiste Bachet; Julien Taieb; Jean-Louis Legoux; Aimery De Gramont; Jaafar Bennouna et al.
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Crossref

Bevacizumab as maintenance therapy in patients with metastatic colorectal cancer: A meta-analysis of individual patients’ data from 3 phase III studies

Cancer Treatment Reviews
2021-06 | Journal article
Contributors: Lisa Salvatore; Emilio Bria; Isabella Sperduti; Axel Hinke; Susanna Hegewisch-Becker; Thomas Aparicio; Karine Le Malicot; Valérie Boige; Dieter Koeberle; Daniela Baertschi et al.
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Crossref

The Activity of Crizotinib in Chemo-Refractory MET-Amplified Esophageal and Gastric Adenocarcinomas: Results from the AcSé-Crizotinib Program

Targeted Oncology
2021-05 | Journal article
Contributors: Thomas Aparicio; Nathalie Cozic; Christelle de la Fouchardière; Emeline Meriaux; Jérome Plaza; Laurent Mineur; Rosine Guimbaud; Emmanuelle Samalin; Florence Mary; Thierry Lecomte et al.
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Crossref

Panel gene profiling of small bowel adenocarcinoma: Results from the NADEGE prospective cohort

International Journal of Cancer
2021-04 | Journal article
Contributors: Thomas Aparicio; Magali Svrcek; Julie Henriques; Pauline Afchain; Astrid Lièvre; David Tougeron; Johan Gagniere; Eric Terrebonne; Guillaume Piessen; Jean‐Louis Legoux et al.
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Crossref

MRI-Based Radiomics Input for Prediction of 2-Year Disease Recurrence in Anal Squamous Cell Carcinoma

Cancers
2021-01 | Journal article | Author
Contributors: Nicolas Giraud; Olivier Saut; Thomas APARICIO; Philippe Ronchin; Louis-Arnaud Bazire; Emilie Barbier; Claire Lemanski; Xavier Mirabel; Pierre-Luc Etienne; Astrid Lièvre et al.
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Multidisciplinary Digital Publishing Institute
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Preferred source (of 2)‎

Small bowel adenocarcinoma: Results from a nationwide prospective ARCAD‐NADEGE cohort study of 347 patients

International Journal of Cancer
2020-08-15 | Journal article
Contributors: Thomas Aparicio; Julie Henriques; Sylvain Manfredi; David Tougeron; Olivier Bouché; Denis Pezet; Guillaume Piessen; Romain Coriat; Aziz Zaanan; Jean‐Louis Legoux et al.
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Crossref

Prognosis and chemosensitivity of deficient MMR phenotype in patients with metastatic colorectal cancer: An AGEO retrospective multicenter study

International Journal of Cancer
2020-07 | Journal article
Contributors: David Tougeron; Benjamin Sueur; Aziz Zaanan; Christelle de la Fouchardiére; David Sefrioui; Thierry Lecomte; Thomas Aparicio; Gaetan Des Guetz; Pascal Artru; Vincent Hautefeuille et al.
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Crossref

Baseline Splenic Volume as a Prognostic Biomarker of FOLFIRI Efficacy and a Surrogate Marker of MDSC Accumulation in Metastatic Colorectal Carcinoma

Cancers
2020-05 | Journal article | Author
Contributors: Julie Niogret; Emeric Limagne; Marion Thibaudin; Julie Blanc; Aurelie Bertaut; Karine Le Malicot; Yves Rinaldi; François-Xavier Caroli-Bosc; Franck Audemar; Suzanne Nguyen et al.
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Multidisciplinary Digital Publishing Institute

Carcinoembryonic Antigen Levels and Survival in Stage III Colon Cancer: Post hoc Analysis of the MOSAIC and PETACC-8 Trials

Cancer Epidemiology, Biomarkers & Prevention
2019-07-01 | Journal article
Contributors: Edouard Auclin; Julien Taieb; Come Lepage; Thomas Aparicio; Roger Faroux; Enrico Mini; Gunnar Folprecht; Ramon Salazar; Magdalena Benetkiewicz; Maria Banzi et al.
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Crossref

Peer review (21 reviews for 13 publications/grants)

Review activity for BMC cancer (1)
Review activity for British journal of cancer. (2)
Review activity for Cancer treatment reviews. (1)
Review activity for Clinical surgical oncology. (1)
Review activity for Clinics and research in hepatology and gastroenterology. (2)
Review activity for Digestive and Liver Disease. (1)
Review activity for Drugs & aging (2)
Review activity for European journal of cancer. (2)
Review activity for Genomics. (2)
Review activity for Journal of geriatric oncology. (3)
Review activity for Journal of the National Cancer Center. (1)
Review activity for Nature communications (1)
Review activity for Targeted oncology. (2)