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Activities

Employment (5)

Sloan Kettering Institute: New York, NY, US

2024-11-04 to present | Associate Lab Director, Core Facilities (Gene trf core facility)
Employment
Source: check_circle
Memorial Sloan Kettering Cancer Center

Pfizer: Pearl River, NY, US

2021-07 to 2024-02 | Associate Director (Vaccine Research and Development)
Employment
Source: Self-asserted source
Carles Martínez-Romero

Icahn School of Medicine at Mount Sinai: New York, NY, US

2017-01-01 to 2021-07 | Assistant Professor (Microbiology)
Employment
Source: Self-asserted source
Carles Martínez-Romero

Icahn School of Medicine at Mount Sinai: New York, NY, US

2013-09-01 to 2016-12-31 | Instructor (Microbiology)
Employment
Source: Self-asserted source
Carles Martínez-Romero

Icahn School of Medicine at Mount Sinai: New York, NY, US

2011-01-01 to 2013-08-31 | Postdoctoral Researcher (Microbiology)
Employment
Source: Self-asserted source
Carles Martínez-Romero

Education and qualifications (2)

Universitat Pompeu Fabra: Barcelona, Catalunya, ES

2005-09-01 to 2009-09-01 | PhD in Health and Life Sciences (Cancer Research Program)
Education
Source: Self-asserted source
Carles Martínez-Romero

Universitat Pompeu Fabra: Barcelona, Catalunya, ES

2005-09-01 to 2007-09-01 | MSc (Cancer Research Program)
Education
Source: Self-asserted source
Carles Martínez-Romero

Professional activities (1)

Icahn School of Medicine at Mount Sinai: New York, NY, US

2016-01-01 to 2021-07 | Board Member (Institutional Animal Care And Use Committee (IACUC))
Invited position
Source: Self-asserted source
Carles Martínez-Romero

Works (32)

Characterization of SARS-CoV-2 Spike mutations important for infection of mice and escape from human immune sera

Nature Communications
2022 | Journal article
EID:

2-s2.0-85133648482

Part of ISSN: 20411723
Contributors: Rathnasinghe, R.; Jangra, S.; Ye, C.; Cupic, A.; Singh, G.; Martínez-Romero, C.; Mulder, L.C.F.; Kehrer, T.; Yildiz, S.; Choi, A. et al.
Source: Self-asserted source
Carles Martínez-Romero via Scopus - Elsevier
grade
Preferred source (of 2)‎

Modeling SARS-CoV-2: Comparative Pathology in Rhesus Macaque and Golden Syrian Hamster Models

Toxicologic Pathology
2022 | Journal article
EID:

2-s2.0-85124340607

Part of ISSN: 15331601 01926233
Contributors: Choudhary, S.; Kanevsky, I.; Yildiz, S.; Sellers, R.S.; Swanson, K.A.; Franks, T.; Rathnasinghe, R.; Munoz-Moreno, R.; Jangra, S.; Gonzalez, O. et al.
Source: Self-asserted source
Carles Martínez-Romero via Scopus - Elsevier

Proteomic Identification of Potential Target Proteins of Cathepsin W for Its Development as a Drug Target for Influenza

Microbiology Spectrum
2022 | Journal article
EID:

2-s2.0-85137136403

Part of ISSN: 21650497
Contributors: Günther, S.C.; Martínez-Romero, C.; Borau, M.S.; Pham, C.T.N.; García-Sastre, A.; Stertz, S.
Source: Self-asserted source
Carles Martínez-Romero via Scopus - Elsevier

Analysis of the evolution of pandemic influenza a(H1N1) virus neuraminidase reveals entanglement of different phenotypic characteristics

mBio
2021 | Journal article
EID:

2-s2.0-85105660692

Part of ISSN: 21507511 21612129
Contributors: Dai, M.; Du, W.; Martínez-Romero, C.; Leenders, T.; Wennekes, T.; Rimmelzwaan, G.F.; van Kuppeveld, F.J.M.; Fouchier, R.A.M.; Garcia-Sastre, A.; de Vries, E. et al.
Source: Self-asserted source
Carles Martínez-Romero via Scopus - Elsevier

IFITM3 incorporation sensitizes influenza A virus to antibody-mediated neutralization

Journal of Experimental Medicine
2021 | Journal article
EID:

2-s2.0-85104841825

Part of ISSN: 15409538 00221007
Contributors: Lanz, C.; Schotsaert, M.; Magnus, C.; Karakus, U.; Hunziker, A.; Borau, M.S.; Martínez-Romero, C.; Spieler, E.E.; Günther, S.C.; Moritz, E. et al.
Source: Self-asserted source
Carles Martínez-Romero via Scopus - Elsevier
grade
Preferred source (of 2)‎

Induction and evasion of type-i interferon responses during influenza a virus infection

Cold Spring Harbor Perspectives in Medicine
2021 | Journal article
EID:

2-s2.0-85117102241

Part of ISSN: 21571422
Contributors: Muñoz-Moreno, R.; Martínez-Romero, C.; García-Sastre, A.
Source: Self-asserted source
Carles Martínez-Romero via Scopus - Elsevier
grade
Preferred source (of 2)‎

Plitidepsin has potent preclinical efficacy against SARS-CoV-2 by targeting the host protein eEF1A

Science
2021 | Journal article
EID:

2-s2.0-85100932017

Part of ISSN: 10959203 00368075
Contributors: White, K.M.; Rosales, R.; Yildiz, S.; Kehrer, T.; Miorin, L.; Moreno, E.; Jangra, S.; Uccellini, M.B.; Rathnasinghe, R.; Coughlan, L. et al.
Source: Self-asserted source
Carles Martínez-Romero via Scopus - Elsevier

The N501Y mutation in SARS-CoV-2 spike leads to morbidity in obese and aged mice and is neutralized by convalescent and post-vaccination human sera

medRxiv
2021 | Other
EID:

2-s2.0-85101209673

Contributors: Rathnasinghe, R.; Jangra, S.; Cupic, A.; Martínez-Romero, C.; Mulder, L.C.F.; Kehrer, T.; Yildiz, S.; Choi, A.; Mena, I.; de Vrieze, J. et al.
Source: Self-asserted source
Carles Martínez-Romero via Scopus - Elsevier

Virus-induced senescence is a driver and therapeutic target in COVID-19

Nature
2021 | Journal article
EID:

2-s2.0-85114771612

Part of ISSN: 14764687 00280836
Contributors: Lee, S.; Yu, Y.; Trimpert, J.; Benthani, F.; Mairhofer, M.; Richter-Pechanska, P.; Wyler, E.; Belenki, D.; Kaltenbrunner, S.; Pammer, M. et al.
Source: Self-asserted source
Carles Martínez-Romero via Scopus - Elsevier

Hybrid Gene Origination Creates Human-Virus Chimeric Proteins during Infection

Cell
2020 | Journal article
EID:

2-s2.0-85086715075

Part of ISSN: 10974172 00928674
Contributors: Ho, J.S.Y.; Angel, M.; Ma, Y.; Sloan, E.; Wang, G.; Martinez-Romero, C.; Alenquer, M.; Roudko, V.; Chung, L.; Zheng, S. et al.
Source: Self-asserted source
Carles Martínez-Romero via Scopus - Elsevier
grade
Preferred source (of 2)‎

Viral Fitness Landscapes in Diverse Host Species Reveal Multiple Evolutionary Lines for the NS1 Gene of Influenza A Viruses

SSRN
2019 | Other
EID:

2-s2.0-85111737916

Part of ISSN: 15565068
Contributors: Muñoz-Moreno, R.; Martínez-Romero, C.; Blanco-Melo, D.; Forst, C.V.; Nachbagauer, R.; Benitez, A.A.; Mena, I.; Aslam, S.; Balasubramaniam, V.; Lee, I. et al.
Source: Self-asserted source
Carles Martínez-Romero via Scopus - Elsevier

Viral Fitness Landscapes in Diverse Host Species Reveal Multiple Evolutionary Lines for the NS1 Gene of Influenza A Viruses

Cell Reports
2019-12-17 | Journal article
Part of ISSN: 2211-1247
Source: Self-asserted source
Carles Martínez-Romero
grade
Preferred source (of 2)‎

Innate Immune Response to Influenza Virus at Single-Cell Resolution in Human Epithelial Cells Revealed Paracrine Induction of Interferon Lambda 1

Journal of Virology
2019-08-02 | Journal article
Part of ISSN: 0022-538X
Part of ISSN: 1098-5514
Source: Self-asserted source
Carles Martínez-Romero
grade
Preferred source (of 2)‎

N-Glycolylneuraminic Acid as a Receptor for Influenza A Viruses

Cell Reports
2019-06 | Journal article
Part of ISSN: 2211-1247
Source: Self-asserted source
Carles Martínez-Romero
grade
Preferred source (of 2)‎

Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry

Cell Discovery
2018-12 | Journal article
Part of ISSN: 2056-5968
Source: Self-asserted source
Carles Martínez-Romero
grade
Preferred source (of 2)‎

Computer-Aided Discovery and Characterization of Novel Ebola Virus Inhibitors

Journal of Medicinal Chemistry
2018-04-26 | Journal article
Part of ISSN: 0022-2623
Part of ISSN: 1520-4804
Source: Self-asserted source
Carles Martínez-Romero
grade
Preferred source (of 2)‎

Specific Mutations in the PB2 Protein of Influenza A Virus Compensate for the Lack of Efficient Interferon Antagonism of the NS1 Protein of Bat Influenza A-Like Viruses

Journal of Virology
2018-01-10 | Journal article
Part of ISSN: 0022-538X
Part of ISSN: 1098-5514
Source: Self-asserted source
Carles Martínez-Romero
grade
Preferred source (of 2)‎

Pandemic H1N1 influenza A viruses suppress immunogenic RIPK3-driven dendritic cell death

Nature Communications
2017-12 | Journal article
Part of ISSN: 2041-1723
Source: Self-asserted source
Carles Martínez-Romero
grade
Preferred source (of 3)‎

Synergistic drug combination effectively blocks Ebola virus infection

Antiviral Research
2017-01 | Journal article
Part of ISSN: 0166-3542
Source: Self-asserted source
Carles Martínez-Romero
grade
Preferred source (of 2)‎

Correction for Eduardo-Correia et al., ISG15 Is Counteracted by Vaccinia Virus E3 Protein and Controls the Proinflammatory Response against Viral Infection

Journal of Virology
2016-12-15 | Journal article
Part of ISSN: 0022-538X
Part of ISSN: 1098-5514
Source: Self-asserted source
Carles Martínez-Romero
grade
Preferred source (of 2)‎

Antiviral Role of IFITM Proteins in African Swine Fever Virus Infection

PLOS ONE
2016-04-26 | Journal article
Part of ISSN: 1932-6203
Source: Self-asserted source
Carles Martínez-Romero
grade
Preferred source (of 2)‎

Characterization of HIV-1 entry inhibitors with broad activity against R5 and X4 viral strains

Journal of Translational Medicine
2015-12 | Journal article
Part of ISSN: 1479-5876
Source: Self-asserted source
Carles Martínez-Romero
grade
Preferred source (of 2)‎

Against the clock towards new Ebola virus therapies

Virus Research
2015-11 | Journal article
Part of ISSN: 0168-1702
Source: Self-asserted source
Carles Martínez-Romero
grade
Preferred source (of 2)‎

The interferon signaling antagonist function of yellow fever virus NS5 protein is activated by type i interferon

Cell Host and Microbe
2014 | Journal article
EID:

2-s2.0-84907700872

Part of ISSN: 19346069 19313128
Contributors: Laurent-Rolle, M.; Morrison, J.; Rajsbaum, R.; Macleod, J.M.L.; Pisanelli, G.; Pham, A.; Ayllon, J.; Miorin, L.; Martínez-Romero, C.; Tenoever, B.R. et al.
Source: Self-asserted source
Carles Martínez-Romero via Scopus - Elsevier

Unanchored K48-Linked Polyubiquitin Synthesized by the E3-Ubiquitin Ligase TRIM6 Stimulates the Interferon-IKKε Kinase-Mediated Antiviral Response

Immunity
2014-06 | Journal article
Part of ISSN: 1074-7613
Source: Self-asserted source
Carles Martínez-Romero
grade
Preferred source (of 2)‎

The Polycomb group protein RING1B is overexpressed in ductal breast carcinoma and is required to sustain FAK steady state levels in breast cancer epithelial cells

Oncotarget
2014-04-30 | Journal article
Part of ISSN: 1949-2553
Source: Self-asserted source
Carles Martínez-Romero

ISG15 Is Counteracted by Vaccinia Virus E3 Protein and Controls the Proinflammatory Response against Viral Infection

Journal of Virology
2014-02-15 | Journal article
Part of ISSN: 0022-538X
Source: Self-asserted source
Carles Martínez-Romero
grade
Preferred source (of 2)‎

Identification of 53 compounds that block Ebola virus-like particle entry via a repurposing screen of approved drugs

Emerging Microbes & Infections
2014-01 | Journal article
Part of ISSN: 2222-1751
Source: Self-asserted source
Carles Martínez-Romero
grade
Preferred source (of 2)‎

Evolution of the Hemagglutinin Protein of the New Pandemic H1N1 Influenza Virus: Maintaining Optimal Receptor Binding by Compensatory Substitutions

Journal of Virology
2013-12-15 | Journal article
Part of ISSN: 0022-538X
Source: Self-asserted source
Carles Martínez-Romero
grade
Preferred source (of 2)‎

Substitutions T200A and E227A in the Hemagglutinin of Pandemic 2009 Influenza A Virus Increase Lethality but Decrease Transmission

Journal of Virology
2013-06-01 | Journal article
Part of ISSN: 0022-538X
Source: Self-asserted source
Carles Martínez-Romero
grade
Preferred source (of 2)‎

Mouse Dendritic Cell (DC) Influenza Virus Infectivity Is Much Lower than That for Human DCs and Is Hemagglutinin Subtype Dependent

Journal of Virology
2013-02-01 | Journal article
Part of ISSN: 0022-538X
Part of ISSN: 1098-5514
Source: Self-asserted source
Carles Martínez-Romero
grade
Preferred source (of 2)‎

The epigenetic regulators Bmi1 and Ring1B are differentially regulated in pancreatitis and pancreatic ductal adenocarcinoma

The Journal of Pathology
2009-10 | Journal article
Part of ISSN: 0022-3417
Part of ISSN: 1096-9896
Source: Self-asserted source
Carles Martínez-Romero