Personal information

Activities

Employment (4)

Universitätsmedizin Göttingen: Göttingen, DE

2022-04-01 to present | Postdoc (Institute for Auditory Neuroscience)
Employment
Source: Self-asserted source
Alexey Alekseev

Moscow Institute of Physics and Technology: Dolgoprudnyy, RU

2021-01-01 to 2022-03-31 | Postdoc, Deputy head of laboratory for theoretical and computer studies of biological macromolecules and genomes (Research Center for Molecular Mechanisms of Aging and Age-related Diseases)
Employment
Source: Self-asserted source
Alexey Alekseev

Moscow Institute of Physics and Technology: Dolgoprudnyy, RU

2019-02-01 to 2020-12-31 | PhD student (Research Center for Molecular Mechanisms of Aging and Age-related Diseases)
Employment
Source: Self-asserted source
Alexey Alekseev

Forschungszentrum Jülich: Jülich, DE

2016-02-01 to 2019-01-31 | PhD student (ICS-6)
Employment
Source: Self-asserted source
Alexey Alekseev

Education and qualifications (3)

RWTH Aachen University: Aachen, Nordrhein-Westfalen, DE

2016-11-01 to 2020-12-07 | Dr. rer. nat (Doktor der Naturwissenschafter, PhD) (Faculty of Georesources and Materials Engineering)
Education
Source: Self-asserted source
Alexey Alekseev

Moscow Institute of Physics and Technology: Dolgoprudnyy, RU

2015-09-01 to 2016-07-15 | Master of Science (Department of General and Applied Physics)
Education
Source: Self-asserted source
Alexey Alekseev

Moscow Institute of Physics and Technology: Dolgoprudnyy, RU

2010-09-01 to 2014-07-15 | Bachelor of Science (Department of General and Applied Physics)
Education
Source: Self-asserted source
Alexey Alekseev

Works (37)

A subgroup of light-driven sodium pumps with an additional Schiff base counterion

Nature Communications
2024 | Journal article
EID:

2-s2.0-85189989726

Part of ISSN: 20411723
Contributors: Podoliak, E.; Lamm, G.H.U.; Marin, E.; Schellbach, A.V.; Fedotov, D.A.; Stetsenko, A.; Asido, M.; Maliar, N.; Bourenkov, G.; Balandin, T. et al.
Source: Self-asserted source
Alexey Alekseev via Scopus - Elsevier

Channelrhodopsin-2 Oligomerization in Cell Membrane Revealed by Photo-Activated Localization Microscopy

Angewandte Chemie - International Edition
2024 | Journal article
EID:

2-s2.0-85184228532

Part of ISSN: 15213773 14337851
Contributors: Bestsennaia, E.; Maslov, I.; Balandin, T.; Alekseev, A.; Yudenko, A.; Abu Shamseye, A.; Zabelskii, D.; Baumann, A.; Catapano, C.; Karathanasis, C. et al.
Source: Self-asserted source
Alexey Alekseev via Scopus - Elsevier

CryoRhodopsins: a comprehensive characterization of a new clade of microbial rhodopsins from cold environments

bioRxiv
2024 | Other
EID:

2-s2.0-85184317272

Part of ISSN: 26928205
Contributors: Lamm, G.H.U.; Marin, E.; Schellbach, A.V.; Stetsenko, A.; Alekseev, A.; Bourenkov, G.; Borshchevskiy, V.; Asido, M.; Agthe, M.; Engilberge, S. et al.
Source: Self-asserted source
Alexey Alekseev via Scopus - Elsevier

Hijacking of internal calcium dynamics by intracellularly residing viral rhodopsins

Nature Communications
2024 | Journal article
EID:

2-s2.0-85181236200

Part of ISSN: 20411723
Contributors: Eria-Oliveira, A.-S.; Folacci, M.; Chassot, A.A.; Fedou, S.; Thézé, N.; Zabelskii, D.; Alekseev, A.; Bamberg, E.; Gordeliy, V.; Sandoz, G. et al.
Source: Self-asserted source
Alexey Alekseev via Scopus - Elsevier

A novel subgroup of light-driven sodium pumps with an additional Schiff base counterion

bioRxiv
2023 | Other
EID:

2-s2.0-85177824001

Part of ISSN: 26928205
Contributors: Podoliak, E.; Lamm, G.H.U.; Alekseev, A.; Marin, E.; Schellbach, A.V.; Fedotov, D.A.; Stetsenko, A.; Maliar, N.; Bourenkov, G.; Balandin, T. et al.
Source: Self-asserted source
Alexey Alekseev via Scopus - Elsevier

Efficient and sustained optogenetic control of nervous and cardiac systems

bioRxiv
2023 | Other
EID:

2-s2.0-85180400245

Part of ISSN: 26928205
Contributors: Zerche, M.; Hunniford, V.; Alekseev, A.; May, F.E.; Vavakou, A.; Siegenthaler, D.; Hüser, M.A.; Kiehn, S.M.; Garrido-Charles, A.; Alvanos, T. et al.
Source: Self-asserted source
Alexey Alekseev via Scopus - Elsevier

Flotillin-associated rhodopsin (FArhodopsin), a widespread paralog of proteorhodopsin in aquatic bacteria with streamlined genomes

mSystems
2023 | Journal article
EID:

2-s2.0-85164232684

Part of ISSN: 23795077
Contributors: Haro-Moreno, J.M.; López-Pérez, M.; Alekseev, A.; Podoliak, E.; Kovalev, K.; Gordeliy, V.; Stepanauskas, R.; Rodriguez-Valera, F.
Source: Self-asserted source
Alexey Alekseev via Scopus - Elsevier

Flotillin-Associated rhodopsin (FArhodopsin), a widespread paralog of proteorhodopsin in aquatic bacteria with streamlined genomes

bioRxiv
2023 | Other
EID:

2-s2.0-85151319428

Part of ISSN: 26928205
Contributors: Haro-Moreno, J.M.; López-Pérez, M.; Alekseev, A.; Podoliak, E.; Kovalev, K.; Gordeliy, V.; Stepanauskas, R.; Rodriguez-Valera, F.
Source: Self-asserted source
Alexey Alekseev via Scopus - Elsevier

Hijacking of internal calcium dynamics by intracellularly residing rhodopsins

bioRxiv
2023 | Other
EID:

2-s2.0-85162039814

Part of ISSN: 26928205
Contributors: Eria-Oliveira, A.-S.; Folacci, M.; Chassot, A.A.; Fedou, S.; Thézé, N.; Zabelskii, D.; Alekseev, A.; Bamberg, E.; Gordeliy, V.; Sandoz, G. et al.
Source: Self-asserted source
Alexey Alekseev via Scopus - Elsevier

Light-Driven Sodium Pump as a Potential Tool for the Control of Seizures in Epilepsy

Molecular Neurobiology
2023 | Journal article
EID:

2-s2.0-85180256254

Part of ISSN: 15591182 08937648
Contributors: Trofimova, A.M.; Amakhin, D.V.; Postnikova, T.Y.; Tiselko, V.S.; Alekseev, A.; Podoliak, E.; Gordeliy, V.I.; Chizhov, A.V.; Zaitsev, A.V.
Source: Self-asserted source
Alexey Alekseev via Scopus - Elsevier

Mechanisms of inward transmembrane proton translocation

Nature Structural and Molecular Biology
2023 | Journal article
EID:

2-s2.0-85163776707

Part of ISSN: 15459985 15459993
Contributors: Kovalev, K.; Tsybrov, F.; Alekseev, A.; Shevchenko, V.; Soloviov, D.; Siletsky, S.; Bourenkov, G.; Agthe, M.; Nikolova, M.; von Stetten, D. et al.
Source: Self-asserted source
Alexey Alekseev via Scopus - Elsevier

Mirror proteorhodopsins

Communications Chemistry
2023 | Journal article
EID:

2-s2.0-85159941986

Part of ISSN: 23993669
Contributors: Okhrimenko, I.S.; Kovalev, K.; Petrovskaya, L.E.; Ilyinsky, N.S.; Alekseev, A.A.; Marin, E.; Rokitskaya, T.I.; Antonenko, Y.N.; Siletsky, S.A.; Popov, P.A. et al.
Source: Self-asserted source
Alexey Alekseev via Scopus - Elsevier

Optogenetic control of lysosome function

bioRxiv
2023 | Other
EID:

2-s2.0-85180008686

Part of ISSN: 26928205
Contributors: Ilyinsky, N.S.; Bukhalovich, S.M.; Bagaeva, D.F.; Alekseev, A.A.; Nesterov, S.V.; Tsybrov, F.M.; Bogorodskiy, A.O.; Nazarova, S.F.; Alekhin, V.A.; Moiseeva, O.V. et al.
Source: Self-asserted source
Alexey Alekseev via Scopus - Elsevier

Retinal-Based Anion Pump from the Cyanobacterium Tolypothrix campylonemoides

Biochemistry (Moscow)
2023 | Journal article
EID:

2-s2.0-85174821957

Part of ISSN: 16083040 00062979
Contributors: Rokitskaya, T.I.; Alekseev, A.A.; Tsybrov, F.M.; Bukhalovich, S.M.; Antonenko, Y.N.; Gordeliy, V.I.
Source: Self-asserted source
Alexey Alekseev via Scopus - Elsevier

Revealing the Oligomerization of Channelrhodopsin-2 in the Cell Membrane using Photo-Activated Localization Microscopy

bioRxiv
2023 | Other
EID:

2-s2.0-85162706698

Part of ISSN: 26928205
Contributors: Bestsennaia, E.; Maslov, I.; Balandin, T.; Alekseev, A.; Yudenko, A.; Shamseye, A.A.; Zabelskii, D.; Baumann, A.; Catapano, C.; Karathanasis, C. et al.
Source: Self-asserted source
Alexey Alekseev via Scopus - Elsevier

E. coli Expression and Purification of Microbial and Viral Rhodopsins

Methods in Molecular Biology
2022 | Book chapter
EID:

2-s2.0-85134854808

Part of ISSN: 19406029 10643745
Contributors: Balandin, T.; Volkov, D.; Alekseev, A.; Kovalev, K.; Bratanov, D.; Gordeliy, V.
Source: Self-asserted source
Alexey Alekseev via Scopus - Elsevier

Microbial Rhodopsins

Methods in Molecular Biology
2022 | Book chapter
EID:

2-s2.0-85134854696

Part of ISSN: 19406029 10643745
Contributors: Gordeliy, V.; Kovalev, K.; Bamberg, E.; Rodriguez-Valera, F.; Zinovev, E.; Zabelskii, D.; Alekseev, A.; Rosselli, R.; Gushchin, I.; Okhrimenko, I.
Source: Self-asserted source
Alexey Alekseev via Scopus - Elsevier

Rhodopsin-Based Optogenetics: Basics and Applications

Methods in Molecular Biology
2022 | Book chapter
EID:

2-s2.0-85134854417

Part of ISSN: 19406029 10643745
Contributors: Alekseev, A.; Gordeliy, V.; Bamberg, E.
Source: Self-asserted source
Alexey Alekseev via Scopus - Elsevier

Structural insights into light-driven anion pumping in cyanobacteria

Nature Communications
2022 | Journal article
EID:

2-s2.0-85140961122

Part of ISSN: 20411723
Contributors: Astashkin, R.; Kovalev, K.; Bukhdruker, S.; Vaganova, S.; Kuzmin, A.; Alekseev, A.; Balandin, T.; Zabelskii, D.; Gushchin, I.; Royant, A. et al.
Source: Self-asserted source
Alexey Alekseev via Scopus - Elsevier

True-atomic-resolution insights into the structure and functional role of linear chains and low-barrier hydrogen bonds in proteins

Nature Structural and Molecular Biology
2022 | Journal article
EID:

2-s2.0-85128921044

Part of ISSN: 15459985 15459993
Contributors: Borshchevskiy, V.; Kovalev, K.; Round, E.; Efremov, R.; Astashkin, R.; Bourenkov, G.; Bratanov, D.; Balandin, T.; Chizhov, I.; Baeken, C. et al.
Source: Self-asserted source
Alexey Alekseev via Scopus - Elsevier

Erratum to: Novel pH-Sensitive Microbial Rhodopsin from Sphingomonas paucimobilis (Doklady Biochemistry and Biophysics, (2020), 495, 1, (342-346), 10.1134/S1607672920060162)

Doklady Biochemistry and Biophysics
2021 | Journal article
EID:

2-s2.0-85104896456

Part of ISSN: 16083091 16076729
Contributors: Maliar, N.; Okhrimenko, I.S.; Petrovskaya, L.E.; Alekseev, A.A.; Kovalev, K.V.; Soloviov, D.V.; Popov, P.A.; Rokitskaya, T.I.; Antonenko, Y.N.; Zabelskii, D.V. et al.
Source: Self-asserted source
Alexey Alekseev via Scopus - Elsevier

Structure-based insights into evolution of rhodopsins

Communications Biology
2021 | Journal article
EID:

2-s2.0-85109149183

Part of ISSN: 23993642
Contributors: Zabelskii, D.; Dmitrieva, N.; Volkov, O.; Shevchenko, V.; Kovalev, K.; Balandin, T.; Soloviov, D.; Astashkin, R.; Zinovev, E.; Alekseev, A. et al.
Source: Self-asserted source
Alexey Alekseev via Scopus - Elsevier

The Voltage Dependent Sidedness of the Reprotonation of the Retinal Schiff Base Determines the Unique Inward Pumping of Xenorhodopsin

Angewandte Chemie - International Edition
2021 | Journal article
EID:

2-s2.0-85114886589

Part of ISSN: 15213773 14337851
Contributors: Weissbecker, J.; Boumrifak, C.; Breyer, M.; Wießalla, T.; Shevchenko, V.; Mager, T.; Slavov, C.; Alekseev, A.; Kovalev, K.; Gordeliy, V. et al.
Source: Self-asserted source
Alexey Alekseev via Scopus - Elsevier

Crystal structure of the N112A mutant of the light-driven sodium pump KR2

Crystals
2020 | Journal article
EID:

2-s2.0-85086268457

Part of ISSN: 20734352
Contributors: Maliar, N.; Kovalev, K.; Baeken, C.; Balandin, T.; Astashkin, R.; Rulev, M.; Alekseev, A.; Ilyinsky, N.; Rogachev, A.; Chupin, V. et al.
Source: Self-asserted source
Alexey Alekseev via Scopus - Elsevier

Erratum: High-resolution structural insights into the heliorhodopsin family (Proceedings of the National Academy of Sciences of the United States of America (2020) 117 (4131-4141) DOI: 10.1073/pnas.1915888117)

Proceedings of the National Academy of Sciences of the United States of America
2020 | Journal article
EID:

2-s2.0-85081995516

Part of ISSN: 10916490 00278424
Contributors: Kovalev, K.; Volkov, D.; Astashkin, R.; Alekseev, A.; Gushchin, I.; Haro-Moreno, J.M.; Chizhov, I.; Siletsky, S.; Mamedov, M.; Rogachev, A. et al.
Source: Self-asserted source
Alexey Alekseev via Scopus - Elsevier

High-resolution structural insights into the heliorhodopsin family

Proceedings of the National Academy of Sciences of the United States of America
2020 | Journal article
EID:

2-s2.0-85080044650

Part of ISSN: 10916490 00278424
Contributors: Kovalev, K.; Volkov, D.; Astashkin, R.; Alekseev, A.; Gushchin, I.; Haro-Moreno, J.M.; Chizhov, I.; Siletsky, S.; Mamedov, M.; Rogachev, A. et al.
Source: Self-asserted source
Alexey Alekseev via Scopus - Elsevier

Molecular mechanism of light-driven sodium pumping

bioRxiv
2020 | Other
EID:

2-s2.0-85095658894

Part of ISSN: 26928205
Contributors: Kovalev, K.; Astashkin, R.; Gushchin, I.; Orekhov, P.; Volkov, D.; Zinovev, E.; Marin, E.; Rulev, M.; Alekseev, A.; Royant, A. et al.
Source: Self-asserted source
Alexey Alekseev via Scopus - Elsevier

Molecular mechanism of light-driven sodium pumping

Nature Communications
2020 | Journal article
EID:

2-s2.0-85084135915

Part of ISSN: 20411723
Contributors: Kovalev, K.; Astashkin, R.; Gushchin, I.; Orekhov, P.; Volkov, D.; Zinovev, E.; Marin, E.; Rulev, M.; Alekseev, A.; Royant, A. et al.
Source: Self-asserted source
Alexey Alekseev via Scopus - Elsevier

Novel pH-Sensitive Microbial Rhodopsin from Sphingomonas paucimobilis

Doklady Biochemistry and Biophysics
2020 | Journal article
EID:

2-s2.0-85098054610

Part of ISSN: 16083091 16076729
Contributors: Maliar, N.; Okhrimenko, I.S.; Petrovskaya, L.E.; Alekseev, A.A.; Kovalev, K.V.; Soloviov, D.V.; Popov, P.A.; Rokitskaya, T.I.; Antonenko, Y.N.; Zabelskii, D.V. et al.
Source: Self-asserted source
Alexey Alekseev via Scopus - Elsevier

Viral channelrhodopsins: Calcium-dependent Na<sup>+</sup>/K<sup>+</sup> selective light-gated channels

bioRxiv
2020 | Other
EID:

2-s2.0-85102724519

Part of ISSN: 26928205
Contributors: Zabelskii, D.; Alekseev, A.; Kovalev, K.; Oliviera, A.-S.; Balandin, T.; Soloviov, D.; Bratanov, D.; Volkov, D.; Vaganova, S.; Astashkin, R. et al.
Source: Self-asserted source
Alexey Alekseev via Scopus - Elsevier

Viral rhodopsins 1 are an unique family of light-gated cation channels

Nature Communications
2020 | Journal article
EID:

2-s2.0-85095845214

Part of ISSN: 20411723
Contributors: Zabelskii, D.; Alekseev, A.; Kovalev, K.; Rankovic, V.; Balandin, T.; Soloviov, D.; Bratanov, D.; Savelyeva, E.; Podolyak, E.; Volkov, D. et al.
Source: Self-asserted source
Alexey Alekseev via Scopus - Elsevier

High resolution structural insights into heliorhodopsin family

bioRxiv
2019 | Other
EID:

2-s2.0-85095655591

Part of ISSN: 26928205
Contributors: Kovalev, K.; Volkov, D.; Astashkin, R.; Alekseev, A.; Gushchin, I.; Haro-Moreno, J.M.; Rogachev, A.; Balandin, T.; Borshchevskiy, V.; Popov, A. et al.
Source: Self-asserted source
Alexey Alekseev via Scopus - Elsevier

Structure and mechanisms of sodium-pumping KR2 rhodopsin

Science Advances
2019 | Journal article
EID:

2-s2.0-85064834050

Part of ISSN: 23752548
Contributors: Kovalev, K.; Polovinkin, V.; Gushchin, I.; Alekseev, A.; Shevchenko, V.; Borshchevskiy, V.; Astashkin, R.; Balandin, T.; Bratanov, D.; Vaganova, S. et al.
Source: Self-asserted source
Alexey Alekseev via Scopus - Elsevier

Unique structure and function of viral rhodopsins

Nature Communications
2019 | Journal article
EID:

2-s2.0-85074299472

Part of ISSN: 20411723
Contributors: Bratanov, D.; Kovalev, K.; Machtens, J.-P.; Astashkin, R.; Chizhov, I.; Soloviov, D.; Volkov, D.; Polovinkin, V.; Zabelskii, D.; Mager, T. et al.
Source: Self-asserted source
Alexey Alekseev via Scopus - Elsevier

Fast iodide-SAD phasing for high-throughput membrane protein structure determination

Science Advances
2017 | Journal article
EID:

2-s2.0-85020572002

Part of ISSN: 23752548
Contributors: Melnikov, I.; Polovinkin, V.; Kovalev, K.; Gushchin, I.; Shevtsov, M.; Shevchenko, V.; Mishin, A.; Alekseev, A.; Rodriguez-Valera, F.; Borshchevskiy, V. et al.
Source: Self-asserted source
Alexey Alekseev via Scopus - Elsevier

Inward H<sup>+</sup> pump xenorhodopsin: Mechanism and alternative optogenetic approach

Science Advances
2017 | Journal article
EID:

2-s2.0-85041702845

Part of ISSN: 23752548
Contributors: Shevchenko, V.; Mager, T.; Kovalev, K.; Polovinkin, V.; Alekseev, A.; Juettner, J.; Chizhov, I.; Bamann, C.; Vavourakis, C.; Ghai, R. et al.
Source: Self-asserted source
Alexey Alekseev via Scopus - Elsevier

Crystal structure of a light-driven sodium pump

Nature Structural and Molecular Biology
2015 | Journal article
EID:

2-s2.0-84929173717

Part of ISSN: 15459985 15459993
Contributors: Gushchin, I.; Shevchenko, V.; Polovinkin, V.; Kovalev, K.; Alekseev, A.; Round, E.; Borshchevskiy, V.; Balandin, T.; Popov, A.; Gensch, T. et al.
Source: Self-asserted source
Alexey Alekseev via Scopus - Elsevier