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Persomed life sciences
Vrije Universiteit Brussel profile page

Other IDs

Loop profile: 2192862

Keywords

RNA, Neoantigens, nucleic acids, immunotherapy, vaccines

Countries

Belgium

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Employment (1)

Vrije Universiteit Brussel: Brussels, BE

Employment
Source: check_circle
Vrije Universiteit Brussel

Education and qualifications (3)

KU Leuven: Leuven, BE

2010-12 to 2016-02 | PhD (Chemistry)
Education
Source: Self-asserted source
Franceschini L.

Oxford University: Oxford, Oxfordshire, GB

2009-09 to 2010-10 | Master Thesis (Chemistry Research Laboratory)
Education
Source: Self-asserted source
Franceschini L.

Sapienza Università di Roma: Rome, IT

2002-09 to 2010-10 | Master Degree (Pharmacy)
Education
Source: Self-asserted source
Franceschini L.

Works (17)

Alpha-galactosylceramide improves the potency of mRNA LNP vaccines against cancer and intracellular bacteria

Journal of Controlled Release
2024-06 | Journal article | Author
DOI: 10.1016/j.jconrel.2024.04.052
SOURCE-WORK-ID:

ffbf2c8b-9cc5-4a3c-a3eb-676878f96686

PMID: 38697317
EID:

2-s2.0-85191978488

WOSUID:

001238661000001
Contributors: Sofie Meulewaeter; Ilke Aernout; Joke Deprez; Yanou Engelen; Margo De Velder; Franceschini L.; Karine Breckpot; Serge Van Calenbergh; Caroline Asselman; Katie Boucher et al.
Source: check_circle
Vrije Universiteit Brussel

Author Correction: Modulating the immune response to SARS-CoV-2 by different nanocarriers delivering an mRNA expressing trimeric RBD of the spike protein: COVARNA Consortium

npj Vaccines
2024-05-18 | Journal article
DOI: 10.1038/s41541-024-00882-4
Contributors: Laura Marcos-Villar; Beatriz Perdiguero; Shubaash Anthiya; Mireya L. Borrajo; Gustavo Lou; Lorenzo Franceschini; Ignasi Esteban; Pedro J. Sánchez-Cordón; Carmen Zamora; Carlos Óscar S. Sorzano et al.
Source: check_circle
Crossref

Modulating the immune response to SARS-CoV-2 by different nanocarriers delivering an mRNA expressing trimeric RBD of the spike protein: COVARNA Consortium

NPJ vaccines
2024-03 | Journal article | Author
DOI: https://doi.org/10.1038/s41541-024-00838-8
SOURCE-WORK-ID:

8b504835-0869-4372-89cb-5936e1748675

EID:

2-s2.0-85187177522

WOSUID:

001179741400001
Contributors: Franceschini L.
Source: check_circle
Vrije Universiteit Brussel
grade
Preferred source (of 2)‎

Assessment of Human SARS CoV-2-Specific T-Cell Responses Elicited In Vitro by New Computationally Designed mRNA Immunogens

Vaccines
2023-12-22 | Journal article | Author
DOI: 10.3390/vaccines12010015
SOURCE-WORK-ID:

b0f241e3-0865-4825-a7c0-d931b5f46d6e

PMID: 38250827
EID:

2-s2.0-85183643077

WOSUID:

001151282200001
Contributors: Ignasi Esteban; Carmen Pastor-Quinones; Lorena Usero; Elena Aurrecoechea; Franceschini L.; Arthur Esprit; Josep Lluis Gelpi; Francisco Martinez-Jimenez; Nuria Lopez-Biga; Karine Breckpot et al.
Source: check_circle
Vrije Universiteit Brussel

An mRNA mix redirects dendritic cells towards an antiviral program, inducing anticancer cytotoxic stem cell and central memory CD8+ T cells

Frontiers in Immunology
2023-03-04 | Journal article | Author
DOI: 10.3389/fimmu.2023.1111523
SOURCE-WORK-ID:

af75dc76-95ca-4f2d-bd3d-7d3a19f7764d

PMID: 36860873
EID:

2-s2.0-85149427206

WOSUID:

000939455200001
Contributors: Wout De Mey; HANNE LOCY; Kirsten De Ridder; Phaedra De Schrijver; Dorien Autaers; Asma Lakdimi; Arthur Esprit; Franceschini L.; Kris Thielemans; Magali Verdonck et al.
Source: check_circle
Vrije Universiteit Brussel

RNA in Cancer Immunotherapy: Unlocking the Potential of the Immune System

Clinical Cancer Research
2022-09-15 | Journal article
DOI: 10.1158/1078-0432.CCR-21-3304
Contributors: Wout De Mey; Arthur Esprit; Kris Thielemans; Karine Breckpot; Lorenzo Franceschini
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

A synthetic DNA template for fast manufacturing of versatile single epitope mRNA

Molecular Therapy Nucleic Acids
2022-09-13 | Journal article | Author
DOI: 10.1016/j.omtn.2022.08.021
SOURCE-WORK-ID:

1c0eb052-c48c-47ad-abf5-333251186c60

PMID: 36159589
EID:

2-s2.0-85137726176

WOSUID:

000858753100006
Contributors: Wout De Mey; Phaedra De Schrijver; Dorien Autaers; Lena Pfitzer; Bruno Fant; HANNE LOCY; Arthur Esprit; Lien Lybaert; Cedric Bogaert; Magali Verdonck et al.
Source: check_circle
Vrije Universiteit Brussel

Unraveling the Effects of a Talimogene Laherparepvec (T-VEC)-Induced Tumor Oncolysate on Myeloid Dendritic Cells

Frontiers in Immunology
2021-10-28 | Journal article | Author
DOI: 10.3389/fimmu.2021.733506
SOURCE-WORK-ID:

71b74bec-a1b2-4ad1-b2e6-945c80214f67

PMID: 34777344
EID:

2-s2.0-85119048005

WOSUID:

000717736900001
Contributors: JENS TIJTGAT; Jolien De Munck; Inès Dufait; Julia Katharina Schwarze; Ivan Van Riet; Franceschini L.; Karine Breckpot; JL Aerts, JLE Aerts; Bart Neyns; Sandra Tuyaerts
Source: check_circle
Vrije Universiteit Brussel

SYNTHETIC DNA TEMPLATE FOR IN VITRO MRNA TRANSCRIPTION

2021-09-23 | Patent | Conceptualization, Methodology, Investigation
Contributors: Franceschini L.
Source: Self-asserted source
Franceschini L.

Neo-Antigen mRNA Vaccines

Vaccines
2020-12-18 | Journal article
DOI: 10.3390/vaccines8040776
Contributors: Arthur Esprit; Wout de Mey; Rajendra Bahadur Shahi; Kris Thielemans; Lorenzo Franceschini; Karine Breckpot
Source: check_circle
Crossref
grade
Preferred source (of 3)‎

mRNA Therapeutics – Generating an optimal drug format

Virtual 8th mRNA Health Conference, 9/11/20
2020-11-09 | Conference abstract | Author
SOURCE-WORK-ID:

34a0c8bc-8b15-42a4-948a-5dd2e19b45a5
Contributors: Wout De Mey; Quentin Lecocq; Dorien Autaers; Karine Breckpot; Kris Thielemans; Franceschini L.
Source: check_circle
Vrije Universiteit Brussel

Gain of 20q11.21 in Human Pluripotent Stem Cells Impairs TGF-β-Dependent Neuroectodermal Commitment.

Stem Cell Reports
2019-07-09 | Journal article | Author
DOI: 10.1016/j.stemcr.2019.05.005
SOURCE-WORK-ID:

7260bc08-241b-4257-bfc9-566d09f17027

EID:

2-s2.0-85068141677

PMID: 31178415
WOSUID:

000474644900013
Contributors: Christina Markouli; Edouard Couvreu De Deckersberg; Marius Regin; Ha Nguyen Thi; Filippo Zambelli; Alexander Scott Keller; Dominika Dziedzicka; Joery De Kock; Laurentijn Tilleman; Filip Van Nieuwerburgh et al.
Source: check_circle
Vrije Universiteit Brussel

MODIFIED NANOPORES, COMPOSITIONS COMPRISING THE SAME, AND USES THEREOF

2017-06-15 | Patent | Conceptualization, Investigation, Methodology, Validation
Contributors: Franceschini L.
Source: Self-asserted source
Franceschini L.

DNA Translocation through Nanopores at Physiological Ionic Strengths Requires Precise Nanoscale Engineering

ACS Nano
2016-09-27 | Journal article
DOI: 10.1021/acsnano.6b03159
Part of ISSN: 1936-0851
Part of ISSN: 1936-086X
Source: Self-asserted source
Franceschini L.
grade
Preferred source (of 2)‎

DNA stretching and optimization of nucleobase recognition in enzymatic nanopore sequencing

Nanotechnology
2015-02-27 | Journal article
DOI: 10.1088/0957-4484/26/8/084002
Part of ISSN: 0957-4484
Part of ISSN: 1361-6528
Source: Self-asserted source
Franceschini L.
grade
Preferred source (of 2)‎

A nanopore machine promotes the vectorial transport of DNA across membranes

Nature Communications
2013-12 | Journal article
DOI: 10.1038/ncomms3415
Part of ISSN: 2041-1723
Source: Self-asserted source
Franceschini L.
grade
Preferred source (of 2)‎

Nucleobase recognition at alkaline pH and apparent pK<sub>a</sub>of single DNA bases immobilised within a biological nanopore

Chem. Commun.
2012 | Journal article
DOI: 10.1039/c1cc16124e
Part of ISSN: 1359-7345
Part of ISSN: 1364-548X
Source: Self-asserted source
Franceschini L.
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