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Employment (6)

EMBL Heidelberg Genome Biology: Heidelberg, Baden-Württemberg, DE

2014-10-01 to present | Staff Scientist / Bioinformatician (SCB unit)
Employment
Source: Self-asserted source
Christian Arnold

Leipzig University: Leipzig, Sachsen, DE

2008-10-01 to 2014-02-28 | Research Associate and Doctoral Candidate (Bioinformatics)
Employment
Source: Self-asserted source
Christian Arnold

Fraunhofer-Institut für Zelltherapie und Immunologie IZI: Leipzig, Sachsen, DE

2011-11 to 2014-02 | Guest Researcher (RNomics group)
Employment
Source: Self-asserted source
Christian Arnold

Harvard University: Cambridge, MA, US

2009-08 to 2013-08 | Research Associate
Employment
Source: Self-asserted source
Christian Arnold

Harvard University: Cambridge, MA, US

2008-08-01 to 2009-07-31 | Lab manager / Research Fellow (Human Evolution)
Employment
Source: Self-asserted source
Christian Arnold

Max Planck Institute for Evolutionary Anthropology: Leipzig, DE

2007-05 to 2008-06 | Research Associate and Graduate Student (Primatology)
Employment
Source: Self-asserted source
Christian Arnold

Education and qualifications (2)

Universität Leipzig: Leipzig, DE

2009-10 to 2014-02 | Dr. rer. nat. (Interdisciplinary Centre for Bioinformatics (IZBI) and the Professur für Bioinformatik)
Education
Source: Self-asserted source
Christian Arnold

Universität Leipzig: Leipzig, DE

2003-10 to 2008-06 | Diploma
Education
Source: Self-asserted source
Christian Arnold

Works (24)

Cytotoxic CD8+ Temra cells show loss of chromatin accessibility at genes associated with T cell activation

Frontiers in Immunology
2024-02-02 | Journal article
DOI: 10.3389/fimmu.2024.1285798
Part of ISSN: 1664-3224
Contributors: Lehte Türk; Igor Filippov; Christian Arnold; Judith Zaugg; Liina Tserel; Kai Kisand; Pärt Peterson
Source: Self-asserted source
Christian Arnold

GRaNIE and GRaNPA: inference and evaluation of enhancer‐mediated gene regulatory networks

Molecular Systems Biology
2023-06-12 | Journal article
DOI: 10.15252/msb.202311627
Part of ISSN: 1744-4292
Part of ISSN: 1744-4292
Contributors: Christian Arnold; Aryan Kamal; Annique Claringbould; Rim Moussa; Nila Hendrika Servaas; Maksim Kholmatov; Neha Daga; Daria Nogina; Sophia Mueller‐Dott; Armando Reyes-Palomares et al.
Source: Self-asserted source
Christian Arnold

MYT1L haploinsufficiency in human neurons and mice causes autism-associated phenotypes that can be reversed by genetic and pharmacologic intervention

Molecular Psychiatry
2023-05 | Journal article
DOI: 10.1038/s41380-023-01959-7
Part of ISSN: 1359-4184
Part of ISSN: 1476-5578
Contributors: Bettina Weigel; Jana Franziska Tegethoff; Sarah Grieder; Bryce Lim; Bhuvaneswari Nagarajan; Yu-Chao Liu; Jule Truberg; Dimitris Papageorgiou; Juan M. Adrian-Segarra; Laura Katharina Schmidt et al.
Source: Self-asserted source
Christian Arnold

Identifying a novel role for the master regulator Tal1 in the Endothelial to Hematopoietic Transition

Scientific Reports
2022-10-10 | Journal article
DOI: 10.1038/s41598-022-20906-0
Part of ISSN: 2045-2322
Contributors: Yasmin Natalia Serina Secanechia; Isabelle Bergiers; Matt Rogon; Christian Arnold; Nicolas Descostes; Stephanie Le; Natalia López-Anguita; Kerstin Ganter; Chrysi Kapsali; Lea Bouilleau et al.
Source: Self-asserted source
Christian Arnold

CDK7/12/13 inhibition targets an oscillating leukemia stem cell network and synergizes with venetoclax in acute myeloid leukemia

EMBO Molecular Medicine
2022-04-07 | Journal article
DOI: 10.15252/emmm.202114990
Part of ISSN: 1757-4676
Part of ISSN: 1757-4684
Contributors: Lixiazi He; Christian Arnold; Judith Thoma; Christian Rohde; Maksim Kholmatov; Swati Garg; Cheng‐Chih Hsiao; Linda Viol; Kaiqing Zhang; Rui Sun et al.
Source: Self-asserted source
Christian Arnold

GRaNIE and GRaNPA: Inference and evaluation of enhancer-mediated gene regulatory networks applied to study macrophages

[]
2021-12-21 | Preprint
DOI: 10.1101/2021.12.18.473290
Contributors: Aryan Kamal; Christian Arnold; Annique Claringbould; Rim Moussa; Nila H. Servaas; Maksim Kholmatov; Neha Daga; Daria Nogina; Sophia Mueller-Dott; Armando Reyes-Palomares et al.
Source: Self-asserted source
Christian Arnold

Identifying a novel role for the master regulator Tal1 in the Endothelial to Hematopoietic Transition

2021-10-03 | Other
DOI: 10.1101/2021.10.03.462906
Contributors: Yasmin Natalia Serina Secanechia; Isabelle Bergiers; Matt Rogon; Christian Arnold; Nicolas Descostes; Stephanie Le; Natalia Lopez Anguita; Kerstin Ganter; Chrysi Kapsali; Lea Bouilleau et al.
Source: check_circle
Crossref

Enhancer-priming in ageing human bone marrow mesenchymal stromal cells contributes to immune traits

[]
2021-09-05 | Preprint
DOI: 10.1101/2021.09.03.458728
Contributors: Mang Ching Lai; Mariana Ruiz-Velasco; Christian Arnold; Olga Sigalova; Daria Bunina; Ivan Berest; Ximing Ding; Marco L. Hennrich; Laura Poisa-Beiro; Annique Claringbould et al.
Source: Self-asserted source
Christian Arnold

Pathological LSD1 mutations repress enhancer-mediated gene regulatory networks in early differentiation

[]
2021-08-11 | Preprint
DOI: 10.1101/2021.08.11.455900
Contributors: Daria Bunina; Pierre-Luc Germain; Alejandro Lopez Tobon; Nadine Fernandez-Novel Marx; Christian Arnold; Andrew Ahern; Annique Claringbould; Mang Ching Lai; Sampath Rangasamy; Vinodh Narayanan et al.
Source: Self-asserted source
Christian Arnold

Hotspot DNMT3A mutations in clonal hematopoiesis and acute myeloid leukemia sensitize cells to azacytidine via viral mimicry response

Nature Cancer
2021-05-25 | Journal article
DOI: 10.1038/s43018-021-00213-9
Part of ISSN: 2662-1347
Contributors: Marina Scheller; Anne Kathrin Ludwig; Stefanie Göllner; Christian Rohde; Stephen Krämer; Sina Stäble; Maike Janssen; James-Arne Müller; Lixiazi He; Nicole Bäumer et al.
Source: Self-asserted source
Christian Arnold

Remodeling of active endothelial enhancers is associated with aberrant gene-regulatory networks in pulmonary arterial hypertension

Nature Communications
2020-12 | Journal article
DOI: 10.1038/s41467-020-15463-x
Part of ISSN: 2041-1723
Source: Self-asserted source
Christian Arnold
grade
Preferred source (of 2)‎

Alzheimer-related genes show accelerated evolution

Molecular Psychiatry
2020-03-13 | Journal article
DOI: 10.1038/s41380-020-0680-1
Part of ISSN: 1359-4184
Part of ISSN: 1476-5578
Source: Self-asserted source
Christian Arnold

Quantification of Differential Transcription Factor Activity and Multiomics-Based Classification into Activators and Repressors: diffTF

Cell Reports
2019-12 | Journal article
DOI: 10.1016/j.celrep.2019.10.106
Part of ISSN: 2211-1247
Source: Self-asserted source
Christian Arnold

SNPhood: investigate, quantify and visualise the epigenomic neighbourhood of SNPs using NGS data.

2016-08 | Journal article
DOI: 10.1093/bioinformatics/btw127
PMID: 27153574
PMC: PMC4965630
Contributors: Arnold C; Bhat P; Zaugg JB
Source: Self-asserted source
Christian Arnold via Europe PubMed Central

Genomic and epigenomic co-evolution in follicular lymphomas.

2015-02 | Journal article
DOI: 10.1038/leu.2014.209
PMID: 25027518
Contributors: Loeffler M; Kreuz M; Haake A; Hasenclever D; Trautmann H; Arnold C; Winter K; Koch K; Klapper W; Scholtysik R et al.
Source: Self-asserted source
Christian Arnold via Europe PubMed Central

CEM-Designer: Design of custom expression microarrays in the post-ENCODE Era

Journal of Biotechnology
2014-11 | Journal article
DOI: 10.1016/j.jbiotec.2014.09.012
Part of ISSN: 0168-1656
Contributors: Christian Arnold; Fabian Externbrink; Jörg Hackermüller; Kristin Reiche
Source: Self-asserted source
Christian Arnold

Chromatin computation: epigenetic inheritance as a pattern reconstruction problem.

2013-11 | Journal article
DOI: 10.1016/j.jtbi.2013.07.012
PMID: 23880640
Contributors: Arnold C; Stadler PF; Prohaska SJ
Source: Self-asserted source
Christian Arnold via Europe PubMed Central

MUTUALISM OR PARASITISM? USING A PHYLOGENETIC APPROACH TO CHARACTERIZE THE OXPECKER‐UNGULATE RELATIONSHIP

Evolution
2011-05 | Journal article
DOI: 10.1111/j.1558-5646.2010.01212.x
Part of ISSN: 0014-3820
Part of ISSN: 1558-5646
Contributors: Charles L. Nunn; Vanessa O. Ezenwa; Christian Arnold; Walter D. Koenig
Source: Self-asserted source
Christian Arnold

Primate extinction risk and historical patterns of speciation and extinction in relation to body mass.

2011-04 | Journal article
DOI: 10.1098/rspb.2010.1489
PMID: 20943699
PMC: PMC3049067
Contributors: Matthews LJ; Arnold C; Machanda Z; Nunn CL
Source: Self-asserted source
Christian Arnold via Europe PubMed Central

Polynomial algorithms for the Maximal Pairing Problem: efficient phylogenetic targeting on arbitrary trees.

2010 | Journal article
DOI: 10.1186/1748-7188-5-25
PMID: 20525185
PMC: PMC2902485
Contributors: Arnold C; Stadler PF
Source: Self-asserted source
Christian Arnold via Europe PubMed Central

Simulating trait evolution for cross-cultural comparison.

2010-12 | Journal article
DOI: 10.1098/rstb.2010.0009
PMID: 21041206
PMC: PMC2981906
Contributors: Nunn CL; Arnold C; Matthews L; Borgerhoff Mulder M
Source: Self-asserted source
Christian Arnold via Europe PubMed Central

Phylogenetic targeting of research effort in evolutionary biology.

2010-11 | Journal article
DOI: 10.1086/656490
PMID: 20887190
Contributors: Arnold C; Nunn CL
Source: Self-asserted source
Christian Arnold via Europe PubMed Central

The 10kTrees website: A new online resource for primate phylogeny

Evolutionary Anthropology: Issues, News, and Reviews
2010-06-23 | Journal article
DOI: 10.1002/evan.20251
Part of ISSN: 1060-1538
Part of ISSN: 1520-6505
Source: Self-asserted source
Christian Arnold

Comparative chewing efficiency in mammalian herbivores

Oikos
2009-11 | Journal article
DOI: 10.1111/j.1600-0706.2009.17807.x
Part of ISSN: 0030-1299
Part of ISSN: 1600-0706
Contributors: Julia Fritz; Jürgen Hummel; Ellen Kienzle; Christian Arnold; Charles Nunn; Marcus Clauss
Source: Self-asserted source
Christian Arnold
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