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Works (14)

Epithelial TNF controls cell differentiation and CFTR activity to maintain intestinal mucin homeostasis

Journal of Clinical Investigation
2023-10-16 | Journal article
DOI: 10.1172/JCI163591
Contributors: Efren A. Reyes; David Castillo-Azofeifa; Jérémie Rispal; Tomas Wald; Rachel K. Zwick; Brisa Palikuqi; Angela Mujukian; Shervin Rabizadeh; Alexander R. Gupta; James M. Gardner et al.
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A DLG1-ARHGAP31-CDC42 axis is essential for the intestinal stem cell response to fluctuating niche Wnt signaling

Cell Stem Cell
2023-02 | Journal article
DOI: 10.1016/j.stem.2022.12.008
Contributors: David Castillo-Azofeifa; Tomas Wald; Efren A. Reyes; Aaron Gallagher; Julia Schanin; Stephanie Vlachos; Nathalie Lamarche-Vane; Carolyn Bomidi; Sarah Blutt; Mary K. Estes et al.
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Cellular shape reinforces niche to stem cell signaling in the small intestine

Science Advances
2022-10-14 | Journal article
DOI: 10.1126/sciadv.abm1847
Contributors: Nalle Pentinmikko; Rodrigo Lozano; Sandra Scharaw; Simon Andersson; Johanna I. Englund; David Castillo-Azofeifa; Aaron Gallagher; Martin Broberg; Ki-Young Song; Agustín Sola Carvajal et al.
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Tools and Concepts for Interrogating and Defining Cellular Identity

Cell Stem Cell
2020 | Journal article
DOI: 10.1016/J.STEM.2020.03.015
WOSUID: WOS:000531103800009
Contributors: McKinley, Kara L.; Castillo-Azofeifa, David; Klein, Ophir D.
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Lgr5+ telocytes are a signaling source at the intestinal villus tip

Nature Communications
2020-04-22 | Journal article
DOI: 10.1038/s41467-020-15714-x
Contributors: Keren Bahar Halpern; Hassan Massalha; Rachel K. Zwick; Andreas E. Moor; David Castillo-Azofeifa; Milena Rozenberg; Lydia Farack; Adi Egozi; Dan R. Miller; Inna Averbukh et al.
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A large pool of actively cycling progenitors orchestrates self-renewal and injury repair of an ectodermal appendage

Nature Cell Biology
2019 | Journal article
DOI: 10.1038/S41556-019-0378-2
WOSUID: WOS:000484363700009
Contributors: Sharir, Amnon; Marangoni, Pauline; Zilionis, Rapolas; Wan, Mian; Wald, Tomas; Hu, Jimmy K.; Kawaguchi, Kyogo; Castillo-Azofeifa, David; Epstein, Leo; Harrington, Kyle et al.
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Atoh1 + secretory progenitors possess renewal capacity independent of Lgr5 + cells during colonic regeneration

The EMBO Journal
2019-02-15 | Journal article
DOI: 10.15252/embj.201899984
Contributors: David Castillo‐Azofeifa; Elena N Fazio; Roy Nattiv; Hayley J Good; Tomas Wald; Michael A Pest; Frederic J de Sauvage; Ophir D Klein; Samuel Asfaha
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Cellular aspect ratio and cell division mechanics underlie the patterning of cell progeny in diverse mammalian epithelia

eLife
2018 | Journal article
DOI: 10.7554/ELIFE.36739
WOSUID: WOS:000458153500001
Contributors: McKinley, Kara L.; Stuurman, Nico; Royer, Loic A.; Schartner, Christoph; Castillo-Azofeifa, David; Delling, Markus; Klein, Ophir D.; Vale, Ronald D.
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Contribution of the two dsRBM motifs to the double-stranded RNA binding and protein interactions of PACT

Journal of Cellular Biochemistry
2018 | Journal article
DOI: 10.1002/JCB.26561
WOSUID: WOS:000426187500056
Contributors: Chukwurah, Evelyn; Willingham, Victoria; Singh, Madhurima; Castillo-Azofeifa, David; Patel, Rekha C.
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Epithelial WNT Ligands Are Essential Drivers of Intestinal Stem Cell Activation

Cell Reports
2018 | Journal article
DOI: 10.1016/J.CELREP.2017.12.093
WOSUID: WOS:000423450900015
Contributors: Zou, Winnie Y.; Blutt, Sarah E.; Zeng, Xi-Lei; Chen, Min-Shan; Lo, Yuan-Hung; Castillo-Azofeifa, David; Klein, Ophir D.; Shroyer, Noah F.; Donowitz, Mark; Estes, Mary K.
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SOX2 regulation by hedgehog signaling controls adult lingual epithelium homeostasis

Development
2018 | Journal article
DOI: 10.1242/DEV.164889
WOSUID: WOS:000440421300017
Contributors: Castillo-Azofeifa, David; Seidel, Kerstin; Gross, Lauren; Golden, Erin J.; Jacquez, Belkis; Klein, Ophir D.; Barlow, Linda A.
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Sonic hedgehog from both nerves and epithelium is a key trophic factor for taste bud maintenance

Development
2017 | Journal article
DOI: 10.1242/DEV.150342
WOSUID: WOS:000408568500006
Contributors: Castillo-Azofeifa, David; Losacco, Justin T.; Salcedo, Ernesto; Golden, Erin J.; Finger, Thomas E.; Barlow, Linda A.
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Induction of ectopic taste buds by SHH reveals the competency and plasticity of adult lingual epithelium

Development
2014 | Journal article
DOI: 10.1242/DEV.107631
WOSUID: WOS:000341304600010
Contributors: Castillo, David; Seidel, Kerstin; Salcedo, Ernesto; Ahn, Christina; de Sauvage, Frederic J.; Klein, Ophir D.; Barlow, Linda A.
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Stress-Induced Phosphorylation of PACT Reduces Its Interaction with TRBP and Leads to PKR Activation

Biochemistry
2011 | Journal article
DOI: 10.1021/BI200104H
WOSUID: WOS:000290837400016
Contributors: Singh, Madhurima; Castillo, David; Patel, Chandrashekhar V.; Patel, Rekha C.
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Peer review (1 review for 1 publication/grant)

Review activity for EMBO reports. (1)
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