Personal information

Drug Discovery and Development, Medicinal Chemistry, Biochemistry, Organic Chemistry, Computational Chemistry, Pharmaceutical Sciences, Glycosaminoglycans and Peptidomimetics, Enzyme Inhibitors and Enzyme Kinetics, Cardiovascular Diseases, Infectious Diseases, Autonomic Nervous System, Endocrinology and GIT Disorders
United States

Activities

Employment (4)

Xavier University of Louisiana: New Orleans, Louisiana, US

2024-04 to present | Professor (Pharmaceutical Sciences)
Employment
Source: Self-asserted source
Rami Al-Horani

Xavier University of Louisiana: New Orleans, LA, US

2020 to 2024-03 | Associate Professor (Division of Pharmaceutical Sciences)
Employment
Source: Self-asserted source
Rami Al-Horani

Xavier University of Louisiana: New Orleans, LA, US

2016 to 2020 | Assistant Professor (Division of Pharmaceutical Sciences)
Employment
Source: Self-asserted source
Rami Al-Horani

Virginia Commonwealth University: Richmond, VA, US

2012 to 2016 | Senior Research Scientist and Postdoctoral Fellow (Department of Medicinal Chemistry & Institute for Structural Biology, Drug Discovery and Development)
Employment
Source: Self-asserted source
Rami Al-Horani

Education and qualifications (4)

Texas A&M University: College Station, Texas, US

2023-03 to 2023-04 | Advanced Certificate in Biopharmaceutical Manufacturing (National Center for Therapeutic Manufacturing)
Education
Source: Self-asserted source
Rami Al-Horani

Virginia Commonwealth University: Richmond, VA, US

2007 to 2012 | Ph.D. (Medicinal Chemistry)
Education
Source: Self-asserted source
Rami Al-Horani

University of Jordan: Amman, JO

2000 to 2003 | M.Sc. (Pharmaceutical Sciences)
Education
Source: Self-asserted source
Rami Al-Horani

University of Jordan: Amman, JO

1995 to 2000 | B. Pharm. (Pharmacy)
Education
Source: Self-asserted source
Rami Al-Horani

Funding (3)

Inhibitors of Human Factor XIIIa as New Anticoagulants

2023-04 to 2027-03 | Grant
National Institute of General Medical Sciences (Bethesda, Maryland, US)
GRANT_NUMBER:

R16GM149412

Source: Self-asserted source
Rami Al-Horani

Inhibitors of the Intrinsic Pathway of Coagulation as New Anticoagulants

2019-04-01 to 2023-03-31 | Grant
National Institute of General Medical Sciences (Bethesda, US)
GRANT_NUMBER: SC3GM131986
Source: Self-asserted source
Rami Al-Horani via DimensionsWizard

Non-Heparin, Sulfated, Readily Synthesized, Allosteric Direct Factor XIa Inhibitors as Potentially Safe Anticoagulants

2012-07-01 to 2014-06-30 | Grant
American Heart Association (Dallas, US)
GRANT_NUMBER:

12POST10930004

Source: Self-asserted source
Rami Al-Horani via DimensionsWizard

Works (50 of 74)

Items per page:
Page 1 of 2

Discovery of a new lead molecule to develop a novel class of human factor XIIa inhibitors

Journal of Thrombosis and Thrombolysis
2024-11-01 | Journal article
Contributors: Anthony Dumas; Navneet Goyal; Madhusoodanan Mottamal; Daniel K. Afosah; Rami A. Al-Horani
Source: check_circle
Crossref

Future is Brighter: New Potential Paradigm-Shifting Medications and Regimens for Diabetes and Obesity

Current Diabetes Reviews
2024-10 | Journal article
Contributors: Rami A. Al-Horani; Kholoud F. Aliter; Hashem F. Aliter
Source: check_circle
Crossref

Discovery of Heparin Mimetic, Potent, and Selective Inhibitors of Human Clotting Factor XIIIa

ACS Omega
2024-07-16 | Journal article
Contributors: Kayla T. Vu; Srabani Kar; Navneet Goyal; Madhusoodanan Mottamal; Daniel K. Afosah; Rami A. Al-Horani
Source: check_circle
Crossref

Sulfopropanoic acid derivatives for treating neurodegenerative disorders: a patent spotlight

Pharmaceutical Patent Analyst
2024-06-20 | Journal article
Contributors: Rami A Al-Horani
Source: check_circle
Crossref

Triple Action of Lignosulfonic Acid Sodium: Anti-protease, Antioxidant, and Anti-inflammatory Effects of a Polymeric Heparin Mimetic

Medicinal Chemistry
2024-05 | Journal article
Contributors: Rami A. Al-Horani; Kholoud F. Aliter
Source: check_circle
Crossref

Educating the public about toxic chemicals that we unknowingly consume: A potential important role for the practicing pharmacists

Journal of the American Pharmacists Association
2024-03 | Journal article
Contributors: Rami A. Al-Horani; Ahlam Ayyad
Source: check_circle
Crossref

Revisiting the effect of cholesteryl sulfate on clotting and fibrinolysis: Inhibition of human thrombin and other human blood proteases

Heliyon
2024-03 | Journal article
Contributors: Rami A. Al-Horani
Source: check_circle
Crossref

New Triazole-Based Potent Inhibitors of Human Factor XIIa as Anticoagulants

ACS Omega
2024-03-05 | Journal article
Contributors: Ma’Lik D. Woodland; Anthony Thompson; Amanda Lipford; Navneet Goyal; John C. Schexnaildre; Madhusoodanan Mottamal; Daniel K. Afosah; Rami A. Al-Horani
Source: check_circle
Crossref

3-(1H-Imidazol-2-Yl)-2,3,8,8a-Tetrahydroindolizin-5(1H)-One Derivatives are Useful as Factor Xia Inhibitors and Their Preparation

Cardiovascular & Hematological Agents in Medicinal Chemistry
2023-11 | Journal article
Contributors: Rami A. Al-Horani
Source: check_circle
Crossref

6-(Arylaminomethyl) Isoquinolines as Enzyme Inhibitors and Their Preparation: A Patent Highlight of Factor XIIa Inhibitors

Cardiovascular & Hematological Agents in Medicinal Chemistry
2023-11 | Journal article
Part of ISSN: 1871-5257
Contributors: Rami A. Al-Horani
Source: Self-asserted source
Rami Al-Horani

Steroid Sulfatase Inhibitors and Sulfated C19 Steroids for Proteotoxicity-Related Diseases: A Patent Spotlight

Pharmaceutical Patent Analyst
2023-09 | Journal article
Contributors: Rami A Al-Horani
Source: check_circle
Crossref

Terlipressin for the Prevention and Treatment of Renal Decline in Hepatorenal Syndrome: A Drug Profile

Gastroenterology Insights
2023-09-28 | Journal article
Contributors: Ahlam Ayyad; Rami A. Al-Horani
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Venous Thromboembolism Prophylaxis in Major Orthopedic Surgeries and Factor XIa Inhibitors

Medical Sciences
2023-08-11 | Journal article
Contributors: Aaryana Jones; Rami A. Al-Horani
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Investigation of the anticoagulant activity of cyclic sulfated glycosaminoglycan mimetics

Carbohydrate Research
2023-07 | Journal article
Contributors: Raquel Chiles; Daniel K. Afosah; Rami A. Al-Horani
Source: check_circle
Crossref

New Era: Mavacamten for Obstructive Hypertrophic Cardiomyopathy

Cardiovascular & Hematological Agents in Medicinal Chemistry
2023-07 | Journal article
Contributors: Rami A. Al-Horani; Ma’Lik Woodland
Source: check_circle
Crossref

Tirzepatide: A New Generation Therapeutic for Diabetes Type 2

Endocrine, Metabolic & Immune Disorders - Drug Targets
2023-07 | Journal article
Part of ISSN: 1871-5303
Contributors: Rami A. Al-Horani; Milad Chedid
Source: Self-asserted source
Rami Al-Horani

Triazol-1-yl Benzamides Promote Anticoagulant Activity via Inhibition of Factor XIIa

Cardiovascular & Hematological Agents in Medicinal Chemistry
2023-07 | Journal article
Part of ISSN: 1871-5257
Contributors: Rami A. Al-Horani; Daniel K. Afosah; Madhusoodanan Mottamal
Source: Self-asserted source
Rami Al-Horani

Homogeneous, Synthetic, Non-Saccharide Glycosaminoglycan Mimetics as Potent Inhibitors of Human Cathepsin G

Biomolecules
2023-04-27 | Journal article
Part of ISSN: 2218-273X
Contributors: Daniel Afosah; Rawan M. Fayyad; Valerie Puliafico; Spencer Merrell; Eltice Langmia; Sophie Diagne; Rami A. Al-Horani; Umesh Desai
Source: Self-asserted source
Rami Al-Horani
grade
Preferred source (of 2)‎

Riluzole and Its Prodrugs for the Treatment of Alzheimer’s Disease

Pharmaceutical Patent Analyst
2023-03 | Journal article
Contributors: Rami A Al-Horani
Source: check_circle
Crossref

4-(Imidazo[1,2-a]pyridin-3-yl): Pyrimidine Derivatives As Anticancer Agents

Pharmaceutical Patent Analyst
2023-01 | Journal article
Contributors: Rami A Al-Horani
Source: check_circle
Crossref

Sulphated penta-galloyl glucopyranoside (SPGG) is glycosaminoglycan mimetic allosteric inhibitor of cathepsin G

RPS Pharmacy and Pharmacology Reports
2023-01-01 | Journal article
Contributors: Rami A Al-Horani; Daniel K Afosah; Srabani Kar; Kholoud F Aliter; Madhusoodanan Mottamal
Source: check_circle
Crossref

Ethacrynic acid is an inhibitor of human factor XIIIa

BMC Pharmacology and Toxicology
2022-12 | Journal article
Part of ISSN: 2050-6511
Source: Self-asserted source
Rami Al-Horani

Vericiguat: A New Hope for Heart Failure Patients

Cardiovascular Therapeutics
2022-12-17 | Journal article
Contributors: Raquel Chiles; Rami A. Al-Horani; Brian Tomlinson
Source: check_circle
Crossref

Sulfonated non‐saccharide molecules and human factor XIa: Enzyme inhibition and computational studies

Chemical Biology & Drug Design
2022-07 | Journal article
Part of ISSN: 1747-0277
Part of ISSN: 1747-0285
Source: Self-asserted source
Rami Al-Horani

First Therapeutic Approval for Eosinophilic Esophagitis

Gastroenterology Insights
2022-07-30 | Journal article
Contributors: Rami A. Al-Horani; Raquel Chiles
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Factor IX(a) inhibitors: an updated patent review (2003-present)

Expert Opinion on Therapeutic Patents
2022-04-03 | Journal article
Contributors: Daniel K. Afosah; Edward Ofori; Madhusoodanan Mottamal; Rami A. Al-Horani
Source: check_circle
Crossref

The market for ulcerative colitis

Nature Reviews Drug Discovery
2022-01 | Journal article
Part of ISSN: 1474-1776
Part of ISSN: 1474-1784
Contributors: Rami Al-Horani; Eleonora Spanudakis; Bashar Hamad
Source: Self-asserted source
Rami Al-Horani

Lignosulfonic Acid Sodium Is a Noncompetitive Inhibitor of Human Factor XIa

Pharmaceuticals
2021-08-31 | Journal article
Contributors: Srabani Kar; Page Bankston; Daniel K. Afosah; Rami A. Al-Horani
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Ethacrynic Acid Is an Inhibitor of Human Factor XIIIa

2021-08-23 | Other
Contributors: Srabani Kar; Kayla Vu; Madhusoodanan Mottamal; Rami A. Al-Horani
Source: check_circle
Crossref

Sulfonated Nonsaccharide Heparin Mimetics Are Potent and Noncompetitive Inhibitors of Human Neutrophil Elastase

ACS Omega
2021-05-18 | Journal article
Contributors: Rami A. Al-Horani; Kholoud F. Aliter; Srabani Kar; Madhusoodanan Mottamal
Source: check_circle
Crossref

Thrombin Inhibition by Argatroban: Potential Therapeutic Benefits in COVID-19

Cardiovascular Drugs and Therapy
2021-04 | Journal article
Contributors: Kholoud F. Aliter; Rami A. Al-Horani
Source: check_circle
Crossref

Potential Therapeutic Benefits of Dipyridamole in COVID-19 Patients

Current Pharmaceutical Design
2021-03-15 | Journal article
Contributors: Kholoud F. Aliter; Rami A. Al-Horani
Source: check_circle
Crossref

Sulfated Non-Saccharide Glycosaminoglycan Mimetics as Novel Drug Discovery Platform for Various Pathologies

Current Medicinal Chemistry
2020 | Journal article
Contributors: Afosah, Daniel K.; Al-Horani, Rami A.
Source: check_circle
Web of Science Researcher Profile Sync

Potential Therapeutic Roles for Direct Factor Xa Inhibitors in Coronavirus Infections

American Journal of Cardiovascular Drugs
2020-12-12 | Journal article
Contributors: Rami A. Al-Horani
Source: check_circle
Crossref

Discovery of Benzyl Tetraphosphonate Derivative as Inhibitor of Human Factor Xia

ChemistryOpen
2020-11 | Journal article
Contributors: Srabani Kar; Madhusoodanan Mottamal; Rami A. Al‐Horani
Source: check_circle
Crossref

Potential Anti-SARS-CoV-2 Therapeutics That Target the Post-Entry Stages of the Viral Life Cycle: A Comprehensive Review

Viruses
2020-09-26 | Journal article
Contributors: Rami A. Al-Horani; Srabani Kar
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Factor XIIIa inhibitors as potential novel drugs for venous thromboembolism

European Journal of Medicinal Chemistry
2020-08 | Journal article
Part of ISSN: 0223-5234
Source: Self-asserted source
Rami Al-Horani

Potential Anti-COVID-19 Therapeutics that Block the Early Stage of the Viral Life Cycle: Structures, Mechanisms, and Clinical Trials

International Journal of Molecular Sciences
2020-07-23 | Journal article
Contributors: Rami A. Al-Horani; Srabani Kar; Kholoud F. Aliter
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Targeting Factor XI(a) for Anticoagulation Therapy: a Patent Landscape

Pharmaceutical Patent Analyst
2020-01 | Journal article
Contributors: Rami A Al-Horani
Source: check_circle
Crossref

Factor XI(a) inhibitors for thrombosis: an updated patent review (2016-present)

Expert Opinion on Therapeutic Patents
2020-01-02 | Journal article
Contributors: Rami A. Al-Horani
Source: check_circle
Crossref

A Synthetic Heparin Mimetic That Allosterically Inhibits Factor XI a and Reduces Thrombosis In Vivo Without Enhanced Risk of Bleeding

Journal of Thrombosis and Haemostasis
2019-08-09 | Journal article
Part of ISSN: 1538-7933
Part of ISSN: 1538-7836
Source: Self-asserted source
Rami Al-Horani
grade
Preferred source (of 2)‎

New Small Molecule Drugs for Thrombocytopenia: Chemical, Pharmacological, and Therapeutic Use Considerations

International Journal of Molecular Sciences
2019-06-20 | Journal article
Contributors: Page Clemons Bankston; Rami A. Al-Horani
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

The In Vitro Effects of Pentamidine Isethionate on Coagulation and Fibrinolysis

Molecules
2019-06-06 | Journal article
Contributors: Rami A. Al-Horani; Daytriona Clemons; Madhusoodanan Mottamal
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Recent advances in the discovery and development of factor XI/XIa inhibitors

Medicinal Research Reviews
2018-09 | Journal article
Contributors: Rami A. Al‐Horani; Daniel K. Afosah
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Inhibition of Herpes Simplex Virus-1 Entry into Human Cells by Nonsaccharide Glycosaminoglycan Mimetics

ACS Medicinal Chemistry Letters
2018-07 | Journal article
Part of ISSN: 1948-5875
Contributors: Rahaman Navaz Gangji; Nehru Viji Sankaranarayanan; James Elste; Rami A. Al-Horani; Daniel K. Afosah; Rachel Joshi; Vaibhav Tiwari; Umesh R. Desai
Source: Self-asserted source
Rami Al-Horani via Crossref Metadata Search
grade
Preferred source (of 2)‎

A small group of sulfated benzofurans induces steady-state submaximal inhibition of thrombin

Bioorganic & Medicinal Chemistry Letters
2018-02-03 | Journal article
Source: Self-asserted source
Rami Al-Horani
grade
Preferred source (of 2)‎

Sulfated Inositol-Based Glycosaminoglycan Mimetics are Homogeneous, Potent, Selective, and Allosteric Inhibitors of Factor XIa

Circulation
2017 | Journal article
Source: check_circle
Web of Science Researcher Profile Sync

Sulfated Inositol-Based Glycosaminoglycan Mimetics are Homogeneous, Potent, Selective, and Allosteric Inhibitors of Factor XIa

Circulation
2017-11-14 | Conference abstract
Source: Self-asserted source
Rami Al-Horani
grade
Preferred source (of 2)‎

Discovery of Chromen-7-yl Furan-2-Carboxylate as a Potent and Selective Factor XIa Inhibitor

Cardiovascular & Hematological Agents in Medicinal Chemistry
2017-11-08 | Journal article
Part of ISSN: 1871-5257
Contributors: Ahmad J. Obaidullah; Rami A. Al-Horani
Source: Self-asserted source
Rami Al-Horani via Crossref Metadata Search
grade
Preferred source (of 2)‎

Potent, Selective, Allosteric Inhibition of Human Plasmin by Sulfated Non-Saccharide Glycosaminoglycan Mimetics

Journal of Medicinal Chemistry
2017-01-05 | Journal article
Part of ISSN: 0022-2623
Contributors: Daniel K. Afosah; Rami A. Al-Horani; Nehru Viji Sankaranarayanan; Umesh R. Desai
Source: Self-asserted source
Rami Al-Horani via Crossref Metadata Search
grade
Preferred source (of 2)‎
Items per page:
Page 1 of 2

Peer review (133 reviews for 33 publications/grants)

Review activity for ACS medicinal chemistry letters. (2)
Review activity for Analytical methods. (1)
Review activity for Antioxidants. (4)
Review activity for Applied sciences. (3)
Review activity for Arabian journal of chemistry. (1)
Review activity for Asian journal of organic chemistry (4)
Review activity for Bioengineering. (1)
Review activity for Biomedicines. (1)
Review activity for Cardiovascular & hematological agents in medicinal chemistry. (10)
Review activity for Catalysts. (1)
Review activity for Chemistry & biodiversity. (5)
Review activity for ChemistrySelect (5)
Review activity for ChemMedChem. (5)
Review activity for Clinical pharmacokinetics (2)
Review activity for Dentistry journal. (2)
Review activity for Expert opinion on drug discovery (2)
Review activity for Expert opinion on emerging drugs (1)
Review activity for Frontiers in pharmacology. (1)
Review activity for International journal of molecular sciences. (9)
Review activity for Journal of chromatographic science. (15)
Review activity for Journal of clinical medicine. (2)
Review activity for Journal of medicinal chemistry. (13)
Review activity for Journal of pharmacy and pharmacology. (3)
Review activity for Marine drugs. (2)
Review activity for Medicina. (2)
Review activity for Medicines. (1)
Review activity for Molecules. (24)
Review activity for Pharmaceuticals. (2)
Review activity for Pharmaceutics. (1)
Review activity for Process biochemistry. (1)
Review activity for Proteomes. (1)
Review activity for Scientific reports. (4)
Review activity for Thrombosis and haemostasis. (2)