Personal information

United States

Activities

Employment (7)

Argo Biopharma: Shanghai, CN

2024-02-01 to present
Employment
Source: Self-asserted source
Mingjian Lu

BeiGene Guangzhou Innovation Technology Co Ltd: Guangzhou, Guangdong, CN

2023-01-04 to 2024-01 | Executive Director, Head of Discovery Biology
Employment
Source: Self-asserted source
Mingjian Lu

BioFronttherapeutics: Beijing, CN

2021-07-01 to 2022-12 | VP, Head of Biology
Employment
Source: Self-asserted source
Mingjian Lu

Pfizer Worldwide Research, Development, and Medical: Cambridge, MA, US

2016-08-01 to 2021-06-30 | Senior Principal Scientist (Internal Medicine Research Unit)
Employment
Source: Self-asserted source
Mingjian Lu

Eli Lilly and Company: Indianapolis, IN, US

2012 to 2016
Employment
Source: Self-asserted source
Mingjian Lu

University of Pennsylvania: Philadelphia, PA, US

2005 to 2012
Employment
Source: Self-asserted source
Mingjian Lu

University of Virginia: Charlottesville, VA, US

2000 to 2005
Employment
Source: Self-asserted source
Mingjian Lu

Education and qualifications (1)

University of Virginia: Charlottesville, VA, US

2000 to 2004 | Ph. D
Education
Source: Self-asserted source
Mingjian Lu

Works (20)

CHAC1 inactivation is effective to preserve muscle glutathione but is insufficient to protect against muscle wasting in cachexia

PLOS ONE
2023-04-04 | Journal article
Contributors: Junjie Li; Zhenquan Jia; Mingjian Lu; Youngwook Ahn; Kevin Cao; Cynthia A. Pinkus; John C. Stansfield; Zhidan Wu; Bei B. Zhang
Source: check_circle
Crossref

Response to Kunos et al. and Lotersztajn and Mallat

Journal of Clinical Investigation
2022-01-04 | Journal article
Contributors: Simeng Wang; Qingzhang Zhu; Guosheng Liang; Tania Franks; Magalie Boucher; Kendra K. Bence; Mingjian Lu; Carlos M. Castorena; Shangang Zhao; Joel K. Elmquist et al.
Source: check_circle
Crossref

Cannabinoid receptor 1 signaling in hepatocytes and stellate cells does not contribute to NAFLD

Journal of Clinical Investigation
2021-11-15 | Journal article
Contributors: Simeng Wang; Qingzhang Zhu; Guosheng Liang; Tania Franks; Magalie Boucher; Kendra K. Bence; Mingjian Lu; Carlos M. Castorena; Shangang Zhao; Joel K. Elmquist et al.
Source: check_circle
Crossref

A thermoplastic microfluidic microphysiological system to recapitulate hepatic function and multicellular interactions.

Biotechnology and bioengineering
2019-10-15 | Journal article
Source: Self-asserted source
Mingjian Lu

A high-throughput microfluidic microphysiological system (PREDICT-96) to recapitulate hepatocyte function in dynamic, re-circulating flow conditions.

Lab on a chip
2019-04-01 | Journal article
Source: Self-asserted source
Mingjian Lu

Comprehensive comparison of MetAP2 tissue and cellular expression pattern in lean and obese rodents.

Diabetes, metabolic syndrome and obesity : targets and therapy
2018-09-28 | Journal article
Source: Self-asserted source
Mingjian Lu

Direct Hepatocyte Insulin Signaling Is Required for Lipogenesis but Is Dispensable for the Suppression of Glucose Production.

Cell metabolism
2016-05-26 | Journal article
Source: Self-asserted source
Mingjian Lu

Akt-mediated foxo1 inhibition is required for liver regeneration.

Hepatology (Baltimore, Md.)
2015-12-18 | Journal article
Source: Self-asserted source
Mingjian Lu

Insulin Is Required to Maintain Albumin Expression by Inhibiting Forkhead Box O1 Protein.

The Journal of biological chemistry
2015-12-14 | Journal article
Source: Self-asserted source
Mingjian Lu

A noncanonical, GSK3-independent pathway controls postprandial hepatic glycogen deposition.

Cell metabolism
2013-07-01 | Journal article
Source: Self-asserted source
Mingjian Lu

A link between the cytoplasmic engulfment protein Elmo1 and the Mediator complex subunit Med31.

Current biology : CB
2012-12-27 | Journal article
Source: Self-asserted source
Mingjian Lu

Insulin regulates liver metabolism in vivo in the absence of hepatic Akt and Foxo1.

Nature medicine
2012-02-19 | Journal article
Source: Self-asserted source
Mingjian Lu

BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module.

Nature
2007-11-01 | Journal article
Source: Self-asserted source
Mingjian Lu

Dock180-ELMO cooperation in Rac activation.

Methods in enzymology
2006-01-01 | Journal article
Source: Self-asserted source
Mingjian Lu

Characterization of a novel interaction between ELMO1 and ERM proteins.

The Journal of biological chemistry
2005-12-23 | Journal article
Source: Self-asserted source
Mingjian Lu

A Steric-inhibition model for regulation of nucleotide exchange via the Dock180 family of GEFs.

Current biology : CB
2005-02-01 | Journal article
Source: Self-asserted source
Mingjian Lu

Phagocytosis of apoptotic cells is regulated by a UNC-73/TRIO-MIG-2/RhoG signaling module and armadillo repeats of CED-12/ELMO.

Current biology : CB
2004-12-01 | Journal article
Source: Self-asserted source
Mingjian Lu

PH domain of ELMO functions in trans to regulate Rac activation via Dock180.

Nature structural & molecular biology
2004-07-11 | Journal article
Source: Self-asserted source
Mingjian Lu

Dock180 and ELMO1 proteins cooperate to promote evolutionarily conserved Rac-dependent cell migration.

The Journal of biological chemistry
2003-11-24 | Journal article
Source: Self-asserted source
Mingjian Lu

Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex.

Nature cell biology
2002-08-01 | Journal article
Source: Self-asserted source
Mingjian Lu