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Works (49)

Pulmonary and Systemic Immune Profiles Following Lung Volume Reduction Surgery and Allogeneic Mesenchymal Stromal Cell Treatment in Emphysema

Cells
2024-09-30 | Journal article
Contributors: Li Jia; Na Li; Vincent van Unen; Jaap-Jan Zwaginga; Jerry Braun; Pieter Hiemstra; Frits Koning; P. Khedoe; Jan Stolk
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A human autoimmune organoid model reveals IL-7 function in coeliac disease

Nature
2024-08-08 | Journal article
Contributors: António J. M. Santos; Vincent van Unen; Zhongqi Lin; Steven M. Chirieleison; Nhi Ha; Arpit Batish; Joshua E. Chan; Jose Cedano; Elisa T. Zhang; Qinghui Mu et al.
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DRA involvement in linaclotide-stimulated bicarbonate secretion during loss of CFTR function

JCI Insight
2024-07-22 | Journal article
Contributors: Jessica B. Sarthi; Annie M. Trumbull; Shayda M. Abazari; Vincent van Unen; Joshua E. Chan; Yanfen Jiang; Jesse Gammons; Marc O. Anderson; Onur Cil; Calvin J. Kuo et al.
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Critical role of down-regulated in adenoma bicarbonate transporter in linaclotide stimulated intestinal bicarbonate secretion

bioRxiv
2023 | Other
EID:

2-s2.0-85163102605

Part of ISSN: 26928205
Contributors: Sarthi, J.B.; Trumbull, A.M.; Abazari, S.M.; van Unen, V.; Chan, J.E.; Joo, N.S.; Jiang, Y.; Kuo, C.J.; Sellers, Z.M.
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Vincent van Unen via Scopus - Elsevier

Impaired distal colonic pH in adults with cystic fibrosis

Journal of Cystic Fibrosis
2023 | Journal article
EID:

2-s2.0-85147015670

Part of ISSN: 18735010 15691993
Contributors: Patel, D.; Mathews, S.; van Unen, V.; Chan, J.E.; Al-Hammadi, N.; Borowitz, D.; Gelfond, D.; Sellers, Z.M.
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Vincent van Unen via Scopus - Elsevier

Mass cytometric analysis unveils a disease-specific immune cell network in the bone marrow in acquired aplastic anemia

Frontiers in Immunology
2023 | Journal article
EID:

2-s2.0-85179316246

Part of ISSN: 16643224
Contributors: Pool, E.S.; Kooy-Winkelaar, Y.; van Unen, V.; Falkenburg, J.H.F.; Koning, F.; Heemskerk, M.H.M.; Tjon, J.M.L.
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Vincent van Unen via Scopus - Elsevier

Therapeutic blood-brain barrier modulation and stroke treatment by a bioengineered FZD4-selective WNT surrogate in mice

Nature Communications
2023-06-02 | Journal article
Contributors: Jie Ding; Sung-Jin Lee; Lukas Vlahos; Kanako Yuki; Cara C. Rada; Vincent van Unen; Meghah Vuppalapaty; Hui Chen; Asmiti Sura; Aaron K. McCormick et al.
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Organoid modeling of lung-resident immune responses to SARS-CoV-2 infection

2023-05-05 | Preprint
Contributors: Calvin Kuo; Shannon Choi; Vincent van Unen; Huimin Zhang; Arjun Rustagi; Samira Alwahabi; António Santos; Joshua Chan; Brandon Lam; Daniel Solis et al.
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Data from The Anatomical Location Shapes the Immune Infiltrate in Tumors of Same Etiology and Affects Survival

2023-03-31 | Preprint
Contributors: Saskia J. Santegoets; Vanessa J. van Ham; Ilina Ehsan; Pornpimol Charoentong; Chantal L. Duurland; Vincent van Unen; Thomas Höllt; Lilly-Ann van der Velden; Sylvia L. van Egmond; Kim E. Kortekaas et al.
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Data from The Anatomical Location Shapes the Immune Infiltrate in Tumors of Same Etiology and Affects Survival

2023-03-31 | Preprint
Contributors: Saskia J. Santegoets; Vanessa J. van Ham; Ilina Ehsan; Pornpimol Charoentong; Chantal L. Duurland; Vincent van Unen; Thomas Höllt; Lilly-Ann van der Velden; Sylvia L. van Egmond; Kim E. Kortekaas et al.
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Figure S1 to S5 from The Anatomical Location Shapes the Immune Infiltrate in Tumors of Same Etiology and Affects Survival

2023-03-31 | Preprint
Contributors: Saskia J. Santegoets; Vanessa J. van Ham; Ilina Ehsan; Pornpimol Charoentong; Chantal L. Duurland; Vincent van Unen; Thomas Höllt; Lilly-Ann van der Velden; Sylvia L. van Egmond; Kim E. Kortekaas et al.
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Figure S1 to S5 from The Anatomical Location Shapes the Immune Infiltrate in Tumors of Same Etiology and Affects Survival

2023-03-31 | Preprint
Contributors: Saskia J. Santegoets; Vanessa J. van Ham; Ilina Ehsan; Pornpimol Charoentong; Chantal L. Duurland; Vincent van Unen; Thomas Höllt; Lilly-Ann van der Velden; Sylvia L. van Egmond; Kim E. Kortekaas et al.
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Table S1 to S3 from The Anatomical Location Shapes the Immune Infiltrate in Tumors of Same Etiology and Affects Survival

2023-03-31 | Preprint
Contributors: Saskia J. Santegoets; Vanessa J. van Ham; Ilina Ehsan; Pornpimol Charoentong; Chantal L. Duurland; Vincent van Unen; Thomas Höllt; Lilly-Ann van der Velden; Sylvia L. van Egmond; Kim E. Kortekaas et al.
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Table S1 to S3 from The Anatomical Location Shapes the Immune Infiltrate in Tumors of Same Etiology and Affects Survival

2023-03-31 | Preprint
Contributors: Saskia J. Santegoets; Vanessa J. van Ham; Ilina Ehsan; Pornpimol Charoentong; Chantal L. Duurland; Vincent van Unen; Thomas Höllt; Lilly-Ann van der Velden; Sylvia L. van Egmond; Kim E. Kortekaas et al.
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Immune subset-committed proliferating cells populate the human foetal intestine throughout the second trimester of gestation

Nature Communications
2023-03-10 | Journal article
Contributors: Nannan Guo; Na Li; Li Jia; Qinyue Jiang; Mette Schreurs; Vincent van Unen; Susana M. Chuva de Sousa Lopes; Alexandra A. Vloemans; Jeroen Eggermont; Boudewijn Lelieveldt et al.
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Identification of a Disease-Associated Network of Intestinal Immune Cells in Treatment-Naive Inflammatory Bowel Disease

Frontiers in Immunology
2022 | Journal article
EID:

2-s2.0-85134033332

Part of ISSN: 16643224
Contributors: van Unen, V.; Ouboter, L.F.; Li, N.; Schreurs, M.; Abdelaal, T.; Kooy-Winkelaar, Y.; Beyrend, G.; Höllt, T.; Maljaars, P.W.J.; Mearin, M.L. et al.
Source: Self-asserted source
Vincent van Unen via Scopus - Elsevier

Therapeutic modulation of the blood-brain barrier and ischemic stroke by a bioengineered FZD4-selective WNT surrogate

bioRxiv
2022 | Other
EID:

2-s2.0-85143577267

Part of ISSN: 26928205
Contributors: Ding, J.; Lee, S.-J.; Vlahos, L.; Yuki, K.; Rada, C.C.; van Unen, V.; Vuppalapaty, M.; Chen, H.; Sura, A.; McCormick, A.K. et al.
Source: Self-asserted source
Vincent van Unen via Scopus - Elsevier

KIR + CD8 + T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19

Science
2022-04-15 | Journal article
Contributors: Jing Li; Maxim Zaslavsky; Yapeng Su; Jing Guo; Michael J. Sikora; Vincent van Unen; Asbjørn Christophersen; Shin-Heng Chiou; Liang Chen; Jiefu Li et al.
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ImaCytE: Visual Exploration of Cellular Micro-Environments for Imaging Mass Cytometry Data

IEEE Transactions on Visualization and Computer Graphics
2021 | Journal article
EID:

2-s2.0-85096884386

Part of ISSN: 19410506 10772626
Contributors: Somarakis, A.; Van Unen, V.; Koning, F.; Lelieveldt, B.; Hollt, T.
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Vincent van Unen via Scopus - Elsevier

Immunoprofiling of early, untreated rheumatoid arthritis using mass cytometry reveals an activated basophil subset inversely linked to ACPA status

Arthritis Research and Therapy
2021 | Journal article
EID:

2-s2.0-85118268784

Part of ISSN: 14786362 14786354
Contributors: Koppejan, H.; Hameetman, M.; Beyrend, G.; van Unen, V.; Kwekkeboom, J.C.; van der Helm-van Mil, A.H.; Toes, R.E.M.; van Gaalen, F.A.
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Vincent van Unen via Scopus - Elsevier

Human KIR+CD8+ T cells target pathogenic T cells in Celiac disease and are active in autoimmune diseases and COVID-19

2021-12-25 | Preprint
Contributors: Jing Li; Maxim Zaslavsky; Yapeng Su; Michael J. Sikora; Vincent van Unen; Asbjørn Christophersen; Shin-Heng Chiou; Liang Chen; Jiefu Li; Xuhuai Ji et al.
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Systems analysis and controlled malaria infection in Europeans and Africans elucidate naturally acquired immunity

Nature Immunology
2021-05 | Journal article
Contributors: Sanne E. de Jong; Vincent van Unen; Mikhael D. Manurung; Koen A. Stam; Jelle J. Goeman; Simon P. Jochems; Thomas Höllt; Nicola Pezzotti; Yoanne D. Mouwenda; Madeleine Eunice Betouke Ongwe et al.
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A 34-Marker Panel for Imaging Mass Cytometric Analysis of Human Snap-Frozen Tissue

Frontiers in Immunology
2020 | Journal article
EID:

2-s2.0-85088839593

Part of ISSN: 16643224
Contributors: Guo, N.; van Unen, V.; Ijsselsteijn, M.E.; Ouboter, L.F.; van der Meulen, A.E.; Chuva de Sousa Lopes, S.M.; de Miranda, N.F.C.C.; Koning, F.; Li, N.
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Vincent van Unen via Scopus - Elsevier

Helminth infections drive heterogeneity in human type 2 and regulatory cells

Science Translational Medicine
2020 | Journal article
EID:

2-s2.0-85077358375

Part of ISSN: 19466242 19466234
Contributors: de Ruiter, K.; Jochems, S.P.; Tahapary, D.L.; Stam, K.A.; König, M.; van Unen, V.; Laban, S.; Höllt, T.; Mbow, M.; Lelieveldt, B.P.F. et al.
Source: Self-asserted source
Vincent van Unen via Scopus - Elsevier

High-dimensional cytometric analysis of colorectal cancer reveals novel mediators of antitumour immunity

Gut
2020 | Journal article
EID:

2-s2.0-85068611003

Part of ISSN: 14683288 00175749
Contributors: De Vries, N.L.; Van Unen, V.; Ijsselsteijn, M.E.; Abdelaal, T.; Van Der Breggen, R.; Farina Sarasqueta, A.; Mahfouz, A.; Peeters, K.C.M.J.; Höllt, T.; Lelieveldt, B.P.F. et al.
Source: Self-asserted source
Vincent van Unen via Scopus - Elsevier

Multidimensional analyses of proinsulin peptide-specific regulatory T cells induced by tolerogenic dendritic cells

Journal of Autoimmunity
2020 | Journal article
EID:

2-s2.0-85075834151

Part of ISSN: 10959157 08968411
Contributors: Suwandi, J.S.; Laban, S.; Vass, K.; Joosten, A.; van Unen, V.; Lelieveldt, B.P.F.; Höllt, T.; Zwaginga, J.J.; Nikolic, T.; Roep, B.O.
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Vincent van Unen via Scopus - Elsevier

Progenitor identification and SARS-CoV-2 infection in long-term human distal lung organoid cultures

bioRxiv
2020 | Other
EID:

2-s2.0-85102909459

Part of ISSN: 26928205
Contributors: Salahudeen, A.A.; Choi, S.S.; Rustagi, A.; Zhu, J.; de Lao, S.M.; Flynn, R.A.; Margalef-Català, M.; Santos, A.J.M.; Ju, J.; Batish, A. et al.
Source: Self-asserted source
Vincent van Unen via Scopus - Elsevier

Visualizing Dynamic Changes at the Maternal-Fetal Interface Throughout Human Pregnancy by Mass Cytometry

Frontiers in Immunology
2020 | Journal article
EID:

2-s2.0-85095699995

Part of ISSN: 16643224
Contributors: van der Zwan, A.; van Unen, V.; Beyrend, G.; Laban, S.; van der Keur, C.; Kapsenberg, H.J.M.; Höllt, T.; Chuva de Sousa Lopes, S.M.; van der Hoorn, M.-L.P.; Koning, F. et al.
Source: Self-asserted source
Vincent van Unen via Scopus - Elsevier

Progenitor identification and SARS-CoV-2 infection in human distal lung organoids

Nature
2020-12-24 | Journal article
Contributors: Ameen A. Salahudeen; Shannon S. Choi; Arjun Rustagi; Junjie Zhu; Vincent van Unen; Sean M. de la O; Ryan A. Flynn; Mar Margalef-Català; António J. M. Santos; Jihang Ju et al.
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Chronic Inflammation Permanently Reshapes Tissue-Resident Immunity in Celiac Disease

Cell
2019 | Journal article
EID:

2-s2.0-85061788990

Part of ISSN: 10974172 00928674
Contributors: Mayassi, T.; Ladell, K.; Gudjonson, H.; McLaren, J.E.; Shaw, D.G.; Tran, M.T.; Rokicka, J.J.; Lawrence, I.; Grenier, J.-C.; van Unen, V. et al.
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Vincent van Unen via Scopus - Elsevier

CyTOFmerge: Integrating mass cytometry data across multiple panels

Bioinformatics
2019 | Journal article
EID:

2-s2.0-85073179136

Part of ISSN: 14602059 13674803
Contributors: Abdelaal, T.; Höllt, T.; Van Unen, V.; Lelieveldt, B.P.F.; Koning, F.; Reinders, M.J.T.; Mahfouz, A.
Source: Self-asserted source
Vincent van Unen via Scopus - Elsevier

Early-life compartmentalization of immune cells in human fetal tissues revealed by high-dimensional mass cytometry

Frontiers in Immunology
2019 | Journal article
EID:

2-s2.0-85071740535

Part of ISSN: 16643224
Contributors: Li, N.; van Unen, V.; Guo, N.; Abdelaal, T.; Somarakis, A.; Eggermont, J.; Mahfouz, A.; Chuva de Sousa Lopes, S.M.; Lelieveldt, B.P.F.; Koning, F.
Source: Self-asserted source
Vincent van Unen via Scopus - Elsevier

Maturing human CD127+ CCR7+ PDL1+ dendritic cells express AIRE in the absence of tissue restricted antigens

Frontiers in Immunology
2019 | Journal article
EID:

2-s2.0-85060649521

Part of ISSN: 16643224
Contributors: Fergusson, J.R.; Morgan, M.D.; Bruchard, M.; Huitema, L.; Heesters, B.A.; van Unen, V.; van Hamburg, J.P.; van der Wel, N.N.; Picavet, D.; Koning, F. et al.
Source: Self-asserted source
Vincent van Unen via Scopus - Elsevier

PD-L1 blockade engages tumor-infiltrating lymphocytes to co-express targetable activating and inhibitory receptors

Journal for ImmunoTherapy of Cancer
2019 | Journal article
EID:

2-s2.0-85070958680

Part of ISSN: 20511426
Contributors: Beyrend, G.; Van Der Gracht, E.; Yilmaz, A.; Van Duikeren, S.; Camps, M.; Höllt, T.; Vilanova, A.; Van Unen, V.; Koning, F.; De Miranda, N.F.C.C. et al.
Source: Self-asserted source
Vincent van Unen via Scopus - Elsevier

Predicting Cell Populations in Single Cell Mass Cytometry Data

Cytometry Part A
2019 | Journal article
EID:

2-s2.0-85062964563

Part of ISSN: 15524930 15524922
Contributors: Abdelaal, T.; van Unen, V.; Höllt, T.; Koning, F.; Reinders, M.J.T.; Mahfouz, A.
Source: Self-asserted source
Vincent van Unen via Scopus - Elsevier

High-resolution imaging and single-cell analysis via laser ablation-inductively coupled plasma-mass spectrometry for the determination of membranous receptor expression levels in breast cancer cell lines using receptor-specific hybrid tracers

Analytica Chimica Acta
2019-10 | Journal article
Contributors: Thibaut Van Acker; Tessa Buckle; Stijn J.M. Van Malderen; Danny M. van Willigen; Vincent van Unen; Fijs W.B. van Leeuwen; Frank Vanhaecke
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Memory CD4+ T cells are generated in the human fetal intestine

Nature Immunology
2019-03-21 | Journal article
Contributors: Na Li; Vincent van Unen; Tamim Abdelaal; Nannan Guo; Sofya A. Kasatskaya; Kristin Ladell; James E. McLaren; Evgeny S. Egorov; Mark Izraelson; Susana M. Chuva de Sousa Lopes et al.
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The Anatomical Location Shapes the Immune Infiltrate in Tumors of Same Etiology and Affects Survival

Clinical Cancer Research
2019-01-01 | Journal article
Contributors: Saskia J. Santegoets; Vanessa J. van Ham; Ilina Ehsan; Pornpimol Charoentong; Chantal L. Duurland; Vincent van Unen; Thomas Höllt; Lilly-Ann van der Velden; Sylvia L. van Egmond; Kim E. Kortekaas et al.
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CyteGuide: Visual Guidance for Hierarchical Single-Cell Analysis

IEEE Transactions on Visualization and Computer Graphics
2018 | Journal article
EID:

2-s2.0-85028725635

Part of ISSN: 10772626
Contributors: Hollt, T.; Pezzotti, N.; Van Unen, V.; Koning, F.; Lelieveldt, B.P.F.; Vilanova, A.
Source: Self-asserted source
Vincent van Unen via Scopus - Elsevier

Intratumoral HPV16-specific T cells constitute a type I–oriented tumor microenvironment to improve survival in HPV16-driven oropharyngeal cancer

Clinical Cancer Research
2018 | Journal article
EID:

2-s2.0-85041623527

Part of ISSN: 15573265 10780432
Contributors: Welters, M.J.P.; Ma, W.; Santegoets, S.J.A.M.; Goedemans, R.; Ehsan, I.; Jordanova, E.S.; Van Ham, V.J.; Van Unen, V.; Koning, F.; Van Egmond, S.I. et al.
Source: Self-asserted source
Vincent van Unen via Scopus - Elsevier

Predicting cell types in single cell mass cytometry data

bioRxiv
2018 | Other
EID:

2-s2.0-85095521772

Part of ISSN: 26928205
Contributors: Abdelaal, T.; van Unen, V.; Höllt, T.; Koning, F.; Reinders, M.J.T.; Mahfouz, A.
Source: Self-asserted source
Vincent van Unen via Scopus - Elsevier

The contribution of cytomegalovirus infection to immune senescence is set by the infectious dose

Frontiers in Immunology
2018 | Journal article
EID:

2-s2.0-85040511317

Part of ISSN: 16643224
Contributors: Redeker, A.; Remmerswaal, E.B.M.; van der Gracht, E.T.I.; Welten, S.P.M.; Höllt, T.; Koning, F.; Cicin-Sain, L.; Nikolich-Žugich, J.; ten Berge, I.J.M.; van Lier, R.A.W. et al.
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Vincent van Unen via Scopus - Elsevier

Heterogeneity of circulating CD8 T-cells specific to islet, neo-antigen and virus in patients with type 1 diabetes mellitus

PLOS ONE
2018-08-08 | Journal article
Contributors: Sandra Laban; Francesco Dieli; Jessica S. Suwandi; Vincent van Unen; Jos Pool; Joris Wesselius; Thomas Höllt; Nicola Pezzotti; Anna Vilanova; Boudewijn P. F. Lelieveldt et al.
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Mass cytometry reveals innate lymphoid cell differentiation pathways in the human fetal intestine

Journal of Experimental Medicine
2018-05-07 | Journal article
Contributors: Na Li; Vincent van Unen; Thomas Höllt; Allan Thompson; Jeroen van Bergen; Nicola Pezzotti; Elmar Eisemann; Anna Vilanova; Susana M. Chuva de Sousa Lopes; Boudewijn P.F. Lelieveldt et al.
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Interactive Visual Analysis of Mass Cytometry Data by Hierarchical Stochastic Neighbor Embedding Reveals Rare Cell Types

bioRxiv
2017 | Other
EID:

2-s2.0-85095639737

Part of ISSN: 26928205
Contributors: van Unen, V.; Höllt, T.; Pezzotti, N.; Li, N.; Reinders, M.J.T.; Eisemann, E.; Koning, F.; Vilanova, A.; Lelieveldt, B.P.F.
Source: Self-asserted source
Vincent van Unen via Scopus - Elsevier

Visual analysis of mass cytometry data by hierarchical stochastic neighbour embedding reveals rare cell types

Nature Communications
2017-11-23 | Journal article
Contributors: Vincent van Unen; Thomas Höllt; Nicola Pezzotti; Na Li; Marcel J. T. Reinders; Elmar Eisemann; Frits Koning; Anna Vilanova; Boudewijn P. F. Lelieveldt
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Cytosplore: Interactive Immune Cell Phenotyping for Large Single-Cell Datasets

Computer Graphics Forum
2016 | Journal article
EID:

2-s2.0-84979021976

Part of ISSN: 14678659 01677055
Contributors: Höllt, T.; Pezzotti, N.; van Unen, V.; Koning, F.; Eisemann, E.; Lelieveldt, B.; Vilanova, A.
Source: Self-asserted source
Vincent van Unen via Scopus - Elsevier

Mass Cytometry of the Human Mucosal Immune System Identifies Tissue- and Disease-Associated Immune Subsets

Immunity
2016 | Journal article
EID:

2-s2.0-84967144030

Part of ISSN: 10974180 10747613
Contributors: van Unen, V.; Li, N.; Molendijk, I.; Temurhan, M.; Höllt, T.; van der Meulen-de Jong, A.E.; Verspaget, H.W.; Mearin, M.L.; Mulder, C.J.; van Bergen, J. et al.
Source: Self-asserted source
Vincent van Unen via Scopus - Elsevier

Tertiary lymphoid structures are confined to patients presenting with unifocal Langerhans Cell Histiocytosis

OncoImmunology
2016 | Journal article
EID:

2-s2.0-84980037521

Part of ISSN: 2162402X 21624011
Contributors: Quispel, W.T.; Steenwijk, E.C.; van Unen, V.; Santos, S.J.; Koens, L.; Mebius, R.; Egeler, R.M.; van Halteren, A.G.S.
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Vincent van Unen via Scopus - Elsevier

Peer review (3 reviews for 2 publications/grants)

Review activity for iScience. (2)
Review activity for Nature communications (1)