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Scopus Author ID: 7004125753

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Employment (7)

RPACT: Sereetz, DE

2017 to present | Founder
Employment
Source: Self-asserted source
Gernot Wassmer

Independent Statistical Consultant: Cologne, DE

2014 to present
Employment
Source: Self-asserted source
Gernot Wassmer

Medical University of Vienna: Vienna, AT

2016-10 to 2017-09 | Guest professor
Employment
Source: Self-asserted source
Gernot Wassmer

Aptiv Solutions: Cologne, DE

2010 to 2014 | SVP (Innovation Center)
Employment
Source: Self-asserted source
Gernot Wassmer

University of Cologne: Cologne, DE

1995 to 2010 | Professor for Medical Statistics (Institute for Medical Statistics, Informatics, and Epidemiology, Cologne )
Employment
Source: Self-asserted source
Gernot Wassmer

GSF: Neuherberg, DE

1993 to 1995 (Institute for Epidemiology)
Employment
Source: Self-asserted source
Gernot Wassmer

Ludwig Maximilian University: Munich, DE

1987 to 1993 (Institute for Statistics)
Employment
Source: Self-asserted source
Gernot Wassmer

Works (50 of 102)

Items per page:
Page 1 of 3

rpact: Confirmatory Adaptive Clinical Trial Design and Analysis

https://cran.r-project.org/package=rpact. R package version 3.3
2022 | Software
Contributors: Wassmer, G.; Pahlke, F.
Source: Self-asserted source
Gernot Wassmer

Adaptive Designs

Handbook of Statistical Methods for Randomized Controlled Trials
2021 | Book chapter
DOI: 10.1201/9781315119694
Contributors: Wassmer, Gernot; König, Franz; Posch, Martin; Kim, K; Bretz, F.; Cheung, Y. K.; Hampson, L.
Source: Self-asserted source
Gernot Wassmer

Group Sequential Designs: A Tutorial

2021 | Journal article
DOI: 10.31234/osf.io/x4azm
Contributors: Lakens, Daniel; Pahlke, Friedrich; Wassmer, Gernot
Source: Self-asserted source
Gernot Wassmer

Efficient Adaptive Designs for Clinical Trials of Interventions for COVID-19

Statistics in biopharmaceutical research
2020 | Journal article
DOI: 10.1080/19466315.2020.1790415
Part of ISSN: 1946-6315
Contributors: Stallard, Nigel; Hampson, Lisa; Benda, Norbert; Brannath, Werner; Burnett, Thomas; Friede, Tim; Kimani, Peter K; Koenig, Franz; Krisam, Johannes; Mozgunov, Pavel et al.
Source: Self-asserted source
Gernot Wassmer

Nested combination tests with a time-to-event endpoint using a short-term endpoint for design adaptations

Pharmaceutical statistics
2019 | Journal article
DOI: 10.1002/pst.1926
Part of ISSN: 1539-1604
Contributors: Jörgens, Silke; Wassmer, Gernot; König, Franz; Posch, Martin
Source: Self-asserted source
Gernot Wassmer

Robustness of testing procedures for confirmatory subpopulation analyses based on a continuous biomarker

Statistical methods in medical research
2019 | Journal article
DOI: 10.1177/0962280218777538
Part of ISSN: 0962-2802
Contributors: Graf, Alex; Wassmer, Gernot; Friede, Tim; Gera, Rol; Gerard; Posch, Martin
Source: Self-asserted source
Gernot Wassmer

Recent advances in methodology for clinical trials in small populations: the InSPiRe project

Orphanet Journal of Rare Diseases
2018-12 | Journal article
DOI: 10.1186/s13023-018-0919-y
Part of ISSN: 1750-1172
Contributors: Tim Friede; Martin Posch; Sarah Zohar; Corinne Alberti; Norbert Benda; Emmanuelle Comets; Simon Day; Alex Dmitrienko; Alexandra Graf; Burak Kürsad Günhan et al.
Source: Self-asserted source
Gernot Wassmer
grade
Preferred source (of 2)‎

Authors' response to comments

Statistics in Medicine
2016 | Journal article
DOI: 10.1002/sim.6823
Part of ISSN: 0277-6715
Contributors: Peter Bauer; Frank Bretz; Vladimir Dragalin; Franz König; Gernot Wassmer
Source: Self-asserted source
Gernot Wassmer
grade
Preferred source (of 2)‎

Group Sequential and Confirmatory Adaptive Designs in Clinical Trials

Springer International Publishing
2016 | Book
DOI: 10.1007/978-3-319-32562-0
ISBN: 9783319325606
ISBN: 9783319325620
Part of ISSN: 2366-8695
Part of ISSN: 2366-8709
Contributors: Gernot Wassmer; Werner Brannath
Source: Self-asserted source
Gernot Wassmer

Twenty-five years of confirmatory adaptive designs: opportunities and pitfalls

Statistics in medicine
2016 | Journal article
DOI: 10.1002/sim.6472
Part of ISSN: 0277-6715
Contributors: Bauer, Peter; Bretz, Frank; Dragalin, Vladimir; König, Franz; Wassmer, Gernot
Source: Self-asserted source
Gernot Wassmer

Adaptive two-stage bioequivalence trials with early stopping and sample size re-estimation

Trials
2015 | Journal article
Part of ISSN: 1745-6215
Contributors: Koenig, Franz; Wolfsegger, Martin; Jaki, Thomas; Schütz, Helmut; Wassmer, Gernot
Source: Self-asserted source
Gernot Wassmer

Designing Issues in Confirmatory Adaptive Population Enrichment Trials

Journal of biopharmaceutical statistics
2015 | Journal article
DOI: 10.1080/10543406.2014.920869
Part of ISSN: 1054-3406
Contributors: Wassmer, Gernot; Dragalin, Vlad
Source: Self-asserted source
Gernot Wassmer

Continuous infusion of clonidine in ventilated newborns and infants: a randomized controlled trial

Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
2014 | Journal article
DOI: 10.1097/pcc.0000000000000151
Part of ISSN: 1529-7535
Contributors: Hünseler, Christoph; Balling, Gunter; Röhlig, Christoph; Blickheuser, Rainer; Trieschmann, Uwe; Lieser, Ulla; Dohna-Schwake, Christian; Gebauer, Corinna; Möller, Oliver; Hering, Fritz et al.
Source: Self-asserted source
Gernot Wassmer

Comparison of three forms of teaching - a prospective randomized pilot trial for the enhancement of adherence

International journal of dental hygiene
2012 | Journal article
DOI: 10.1111/j.1601-5037.2011.00543.x
Part of ISSN: 1601-5029
Contributors: Reinhardt, CH; Noack, MJ; Wassmer, G; Dumit, J; Rolfs, A; Klein, K
Source: Self-asserted source
Gernot Wassmer

Efficacy and safety of moxifloxacin as antibacterial prophylaxis for patients receiving autologous haematopoietic stem cell transplantation: a randomised trial

International journal of antimicrobial agents
2012 | Journal article
DOI: 10.1016/j.ijantimicag.2011.10.009
Part of ISSN: 0924-8579
Contributors: Vehreschild, J Janne; Moritz, Gregor; Vehreschild, Maria J G T; Arenz, Dorothee; Mahne, Martina; Bredenfeld, Henning; Chemnitz, Jens; Klein, Florian; Cremer, Birgit; Böll, Boris et al.
Source: Self-asserted source
Gernot Wassmer

Multiple sclerosis and extract of cannabis: results of the MUSEC trial

Journal of neurology, neurosurgery, and psychiatry
2012 | Journal article
DOI: 10.1136/jnnp-2012-302468
Part of ISSN: 0022-3050
Contributors: Zajicek, John Peter; Hobart, Jeremy C; Slade, Anita; Barnes, David; Mattison, Paul G; MUSEC Research Group
Source: Self-asserted source
Gernot Wassmer

Preoperative statin therapy for patients undergoing cardiac surgery

The Cochrane database of systematic reviews
2012 | Journal article
DOI: 10.1002/14651858.cd008493.pub2
Part of ISSN: 1469-493X
Contributors: Liakopoulos, Oliver J; Kuhn, Elmar W; Slottosch, Ingo; Wassmer, Gernot; Wahlers, Thorsten
Source: Self-asserted source
Gernot Wassmer

ADDPLAN: Adaptive Designs -- Plans and Analyses

2011 | Manual
Contributors: Wassmer, G.
Source: Self-asserted source
Gernot Wassmer

On sample size determination in multi-armed confirmatory adaptive designs

Journal of biopharmaceutical statistics
2011 | Journal article
DOI: 10.1080/10543406.2011.551336
Part of ISSN: 1054-3406
Contributors: Wassmer, Gernot
Source: Self-asserted source
Gernot Wassmer

Voriconazole serum concentrations in prophylactically treated acute myelogenous leukaemia patients

Mycoses
2011 | Journal article
DOI: 10.1111/j.1439-0507.2009.01803.x
Part of ISSN: 0933-7407
Contributors: Rüping, Maria J G T; Müller, Carsten; Vehreschild, Jörg J; Böhme, Angelika; Mousset, Sabine; Harnischmacher, Urs; Frommolt, Peter; Wassmer, Gernot; Drzisga, Ivonne; Hallek, Michael et al.
Source: Self-asserted source
Gernot Wassmer

A strategy for encouraging young adults' adoption of a preferred oral hygiene technique

Oral health & preventive dentistry
2010 | Journal article
Part of ISSN: 1602-1622
Contributors: Reinhardt, Claus H; Noack, Michael J; Wassmer, Gernot; Hurrelmann, Klaus; Klein, Klaus
Source: Self-asserted source
Gernot Wassmer

Adaptive Interim Analyses in Clinical Trials

Handbook of Adaptive Designs in Pharmaceutical and Clinical Development
2010 | Book chapter
DOI: 10.1201/b10279
Contributors: Wassmer, G.; Pong, A.; Pong, S.-C.
Source: Self-asserted source
Gernot Wassmer

Comments on the draft guidance on "adaptive design clinical trials for drugs and biologics" of the U.S. Food and Drug Administration

Journal of biopharmaceutical statistics
2010 | Journal article
DOI: 10.1080/10543406.2010.514453
Part of ISSN: 1054-3406
Contributors: Brannath, Werner; Burger, Hans Ulrich; Glimm, Ekkehard; Stallard, Nigel; V; emeulebroecke, Marc; Wassmer, Gernot
Source: Self-asserted source
Gernot Wassmer

Myocardial protection in cardiac surgery patients requiring prolonged aortic cross-clamp times: a single-center evaluation of clinical outcomes comparing two blood cardioplegic strategies

The Journal of cardiovascular surgery
2010 | Journal article
Part of ISSN: 0021-9509
Contributors: Liakopoulos, OJ; Kuhn, EW; Choi, YH; Chang, W; Wittwer, T; Madershahian, N; Wassmer, G; Wahlers, T
Source: Self-asserted source
Gernot Wassmer

Dental caries experience of schoolchildren of two different oral health care delivery systems

International dental journal
2009 | Journal article
Part of ISSN: 0020-6539
Contributors: Sagheri, Darius; Wassmer, Gernot; Hahn, Petra; McLoughlin, Jacinta
Source: Self-asserted source
Gernot Wassmer

Group Sequential Designs

Encyclopedia of Clinical Trials
2009 | Book chapter
DOI: 10.1002/9780471462422.eoct024
Contributors: Wassmer, G.; D'Agostino, R. B.; Sullivan, L. M.; Massaro, J. M.
Source: Self-asserted source
Gernot Wassmer

Human fetal adiponectin and retinol-binding protein (RBP)-4 levels in relation to birth weight and maternal obesity

Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association
2009 | Journal article
DOI: 10.1055/s-0028-1100379
Part of ISSN: 0947-7349
Contributors: Laudes, M; Oberhauser, F; Bilkovski, R; Schubert, M; Udelhoven, M; Wassmer, G; Roth, B; Krone, W
Source: Self-asserted source
Gernot Wassmer

Interventional therapy of bifurcation lesions: a TIMI flow-guided concept to treat side branches in bifurcation lesions--a prospective randomized clinical study (Thueringer bifurcation study, THUEBIS study as pilot trial)

Circulation. Cardiovascular interventions
2009 | Journal article
DOI: 10.1161/circinterventions.108.833046
Part of ISSN: 1941-7640
Contributors: Korn, Hubertus V; Yu, Jiangtao; Ohlow, Marc A; Huegl, Burkhard; Schulte, Walter; Wagner, Andreas; Wassmer, Gernot; Gruene, Stefan; Petek, Oliver; Lauer, Bernward
Source: Self-asserted source
Gernot Wassmer

Statins for prevention of atrial fibrillation after cardiac surgery: a systematic literature review

The Journal of thoracic and cardiovascular surgery
2009 | Journal article
DOI: 10.1016/j.jtcvs.2009.03.054
Part of ISSN: 0022-5223
Contributors: Liakopoulos, Oliver J; Choi, Yeong-Hoon; Kuhn, Elmar W; Wittwer, Thorsten; Borys, Michal; Madershahian, Navid; Wassmer, Gernot; Wahlers, Thorsten
Source: Self-asserted source
Gernot Wassmer

A Note on Repeated P--Values for Group Sequential Designs

Biometrika
2008 | Journal article
DOI: 10.1093/biomet/asm080
Contributors: Posch, M.; Wassmer, G.; Brannath, W.
Source: Self-asserted source
Gernot Wassmer

Impact of preoperative statin therapy on adverse postoperative outcomes in patients undergoing cardiac surgery: a meta-analysis of over 30,000 patients

European heart journal
2008 | Journal article
DOI: 10.1093/eurheartj/ehn198
Part of ISSN: 0195-668X
Contributors: Liakopoulos, Oliver J; Choi, Yeong-Hoon; Haldenwang, Peter L; Strauch, Justus; Wittwer, Thorsten; Dörge, Hilmar; Stamm, Christof; Wassmer, Gernot; Wahlers, Thorsten
Source: Self-asserted source
Gernot Wassmer

Inefficacy of different strategies to improve guideline awareness - 5-year follow-up of the hypertension evaluation project (HEP)

Trials
2008 | Journal article
DOI: 10.1186/1745-6215-9-39
Part of ISSN: 1745-6215
Contributors: Hagemeister, Jens; Schneider, Christian A; Diedrichs, Holger; Mebus, Diana; Pfaff, Holger; Wassmer, Gernot; Höpp, Hans W
Source: Self-asserted source
Gernot Wassmer

[Prophylaxis of contrast-induced nephropathy with N-acetylcysteine]

Zentralblatt fur Chirurgie
2007 | Journal article
DOI: 10.1055/s-2007-960756
Part of ISSN: 0044-409X
Contributors: Gawenda, M; Möller, A; Wassmer, G; Brunkwall, J
Source: Self-asserted source
Gernot Wassmer

A double-blind trial on prophylactic voriconazole (VRC) or placebo during induction chemotherapy for acute myelogenous leukaemia (AML)

The Journal of infection
2007 | Journal article
DOI: 10.1016/j.jinf.2007.07.003
Part of ISSN: 0163-4453
Contributors: Vehreschild, Jörg J; Böhme, Angelika; Buchheidt, Dieter; Arenz, Dorothee; Harnischmacher, Urs; Heussel, Claus P; Ullmann, Andrew J; Mousset, Sabine; Hummel, Margit; Frommolt, Peter et al.
Source: Self-asserted source
Gernot Wassmer

A brief review on software developments for group sequential and adaptive designs

Biometrical journal. Biometrische Zeitschrift
2006 | Journal article
DOI: 10.1002/bimj.200510233
Part of ISSN: 0323-3847
Contributors: Wassmer, Gernot; V; emeulebroecke, Marc
Source: Self-asserted source
Gernot Wassmer

Discussion of ``Executive Summary of the PhRMA Working Group on Adaptive Designs in Clinical Drug Development''

Journal of Biopharmaceutical Statistics
2006 | Journal article
DOI: 10.1080/10543400600609692
Contributors: Wassmer, Gernot
Source: Self-asserted source
Gernot Wassmer

Improved lipid profiles and maintenance of virologic control in heavily pretreated HIV-infected patients who switched from stavudine to tenofovir treatment

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
2006 | Journal article
DOI: 10.1086/498516
Part of ISSN: 1058-4838
Contributors: Schewe, Carl Knud; Maserati, Renato; Wassmer, Gernot; Adam, Axel; Weitner, Lutwin
Source: Self-asserted source
Gernot Wassmer

Planning and analyzing adaptive group sequential survival trials

Biometrical journal. Biometrische Zeitschrift
2006 | Journal article
DOI: 10.1002/bimj.200510190
Part of ISSN: 0323-3847
Contributors: Wassmer, Gernot
Source: Self-asserted source
Gernot Wassmer

What is the value of available risk-scores in predicting postoperative complications after aorto-iliac surgery? A prospective non randomized study

The Journal of cardiovascular surgery
2006 | Journal article
Part of ISSN: 0021-9509
Contributors: Wolters, U; Mannheim, S; Wassmer, G; Brunkwall, J
Source: Self-asserted source
Gernot Wassmer

Comparison of magnetic resonance imaging and computed tomography of 8 aortic stent-graft models

Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists
2004 | Journal article
DOI: 10.1583/03-1130mr.1
Part of ISSN: 1526-6028
Contributors: Gawenda, Michael; Gossmann, Axel; Krüger, Karsten; Zaehringer, Markus; Hahn, Moritz; Wassmer, Gernot; Brunkwall, Jan
Source: Self-asserted source
Gernot Wassmer

Endotension is influenced by wall compliance in a latex aneurysm model

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery
2004 | Journal article
DOI: 10.1016/j.ejvs.2003.10.013
Part of ISSN: 1078-5884
Contributors: Gawenda, M; Knez, P; Winter, St; Jaschke, G; Wassmer, G; Schmitz-Rixen, Th; Brunkwall, J
Source: Self-asserted source
Gernot Wassmer

Minimization of sample size when comparing two small probabilities in a non-inferiority safety trial

Statistics in medicine
2004 | Journal article
DOI: 10.1002/sim.1953
Part of ISSN: 0277-6715
Contributors: Röhmel, Joachim; Wassmer, Gernot
Source: Self-asserted source
Gernot Wassmer

Multistage adaptive designs for clinical trials

Drug discovery today
2004 | Journal article
DOI: 10.1016/s1359-6446(04)03090-9
Part of ISSN: 1359-6446
Contributors: Wassmer, Gernot
Source: Self-asserted source
Gernot Wassmer

Perioperative granulocyte colony-stimulating factor does not prevent severe infections in patients undergoing esophagectomy for esophageal cancer: a randomized placebo-controlled clinical trial

Annals of surgery
2004 | Journal article
DOI: 10.1097/01.sla.0000129705.00210.24
Part of ISSN: 0003-4932
Contributors: Schaefer, Hartmut; Engert, Andreas; Grass, Guido; Mansmann, Georg; Wassmer, Gernot; Hubel, Kai; Loehlein, Dietrich; Ulrich, Bernward C; Lippert, Hans; Knoefel, Wolfram T et al.
Source: Self-asserted source
Gernot Wassmer

Accelerating Clinical Trials by Flexible Designs

Good Clinical Practice Journal
2003 | Journal article
Part of ISSN: 1350-0961
Contributors: Ziegler, A.; Dahmen, G.; König, I. R.; Wassmer, G.; Hildebr; Birth, M.
Source: Self-asserted source
Gernot Wassmer

Analyzing randomized dose finding studies with a primary and a secondary endpoint

Journal of biopharmaceutical statistics
2003 | Journal article
DOI: 10.1081/bip-120019273
Part of ISSN: 1054-3406
Contributors: Hothorn, Ludwig A; Wassmer, Gernot
Source: Self-asserted source
Gernot Wassmer

Association of the vitamin D receptor genotype with bone metastases in breast cancer patients

Oncology
2003 | Journal article
DOI: 10.1159/000067767
Part of ISSN: 0030-2414
Contributors: Schöndorf, Thomas; Eisberg, Carsten; Wassmer, Gernot; Warm, Mathias; Becker, Martina; Rein, Daniel T; Göhring, Uwe-Jochen
Source: Self-asserted source
Gernot Wassmer

Data-driven analysis strategies for proportion studies in adaptive group sequential test designs

Journal of biopharmaceutical statistics
2003 | Journal article
DOI: 10.1081/bip-120024196
Part of ISSN: 1054-3406
Contributors: Wassmer, Gernot
Source: Self-asserted source
Gernot Wassmer

Efficacy of extract of Pelargonium sidoides in children with acute non-group A beta-hemolytic streptococcus tonsillopharyngitis: a randomized, double-blind, placebo-controlled trial

Alternative therapies in health and medicine
2003 | Journal article
Part of ISSN: 1078-6791
Contributors: Bereznoy, Viatcheslav V; Riley, David S; Wassmer, Gernot; Heger, Marianne
Source: Self-asserted source
Gernot Wassmer

Endotension as a result of pressure transmission through the graft following endovascular aneurysm repair--an in vitro study

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery
2003 | Journal article
DOI: 10.1016/s1078-5884(03)00378-2
Part of ISSN: 1078-5884
Contributors: Gawenda, M; Jaschke, G; Winter, St; Wassmer, G; Brunkwall, J
Source: Self-asserted source
Gernot Wassmer
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