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Loop profile: 1289081

Keywords

obesity-cancer axis, leptin signaling, breast cancer, patient-derived xenograft

Countries

United States

Biography

I'm an MD/PhD Candidate in Dr. Matthew Burow and Dr. Bridgette Collins-Burow's laboratory at Tulane University School of Medicine. My research examines the obesity-cancer axis in the context of triple negative breast cancer, with a focus on leptin signaling's role in promoting tumor growth and metastasis.

Activities

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Employment (1)

University of Texas MD Anderson Cancer Center: Houston, TX, US

2015-11 to 2018-05 | Research Assistant (Genetics)
Employment
Source: Self-asserted source
Courtney B. Lagarde

Education and qualifications (2)

Tulane University School of Medicine: New Orleans, LA, US

2018-06 to present | MD/PhD Candidate (Physician-Scientist Program)
Education
Source: Self-asserted source
Courtney B. Lagarde

St Edward's University: Austin, TX, US

2011 to 2015 | BS Biology
Education
Source: Self-asserted source
Courtney B. Lagarde

Professional activities (2)

Tulane University School of Medicine: New Orleans, LA, US

2023-04 | Graduate Student Employee of the Year
Distinction
Source: Self-asserted source
Courtney B. Lagarde

Southern Society for Clinical Investigation: New Orleans, US

2022-02 | Student Travel Award
Distinction
Source: Self-asserted source
Courtney B. Lagarde

Funding (1)

Title: Leptin Signaling in the Obese Tumor Microenvironment in Triple Negative Breast Cancer

Grant
UAB Center for Clinical and Translational Science, NIH Ruth L. Kirschstein National Research Service Award (NRSA) (Birmingham, Alabama , US)
GRANT_NUMBER:

TL1TR003106

Source: Self-asserted source
Courtney B. Lagarde

Works (8)

Obesity and leptin in breast cancer angiogenesis

Frontiers in Endocrinology
2024-10-08 | Journal article
DOI: 10.3389/fendo.2024.1465727
Part of ISSN: 1664-2392
Contributors: Courtney B. Lagarde; Kapil Thapa; Nicole M. Cullen; Mackenzie L. Hawes; Khudeja Salim; Megan C. Benz; Sophie R. Dietrich; Brandon E. Burow; Bruce A. Bunnell; Elizabeth C. Martin et al.
Source: Self-asserted source
Courtney B. Lagarde

Obesity-associated epigenetic alterations and the obesity-breast cancer axis

Oncogene
2024-02-03 | Journal article | Author
DOI: 10.1038/s41388-024-02954-0
Part of ISSN: 0950-9232
Part of ISSN: 1476-5594
Contributors: Courtney B. Lagarde; Joachim Kavalakatt; Megan C. Benz; Mackenzie L. Hawes; Carter A. Arbogast; Nicole M. Cullen; Emily C. McConnell; Caroline Rinderle; Katherine L. Hebert; Maninder Khosla et al.
Source: Self-asserted source
Courtney B. Lagarde
grade
Preferred source (of 2)‎

The effect of obesity on adipose-derived stromal cells and adipose tissue and their impact on cancer.

Cancer Metastasis Reviews
2022-08-24 | Journal article
DOI: 10.1007/s10555-022-10063-1
PMID: 35999486
Contributors: Bruce Bunnell; Martin EC; Matossian MD; Brock CK; Nguyen K; Collins-Burow B; Burow ME
Source: Self-asserted source
Courtney B. Lagarde

Expression of Novel Kinase MAP3K19 in Various Cancers and Survival Correlations.

Frontiers in Bioscience (Landmark edition)
2022-06-01 | Journal article
DOI: 10.31083/j.fbl2706196
PMID: 35748272
Contributors: Nguyen K; Yousefi H; Cheng T; Magrath J; Hartono AB; Alzoubi M; Hebert K; Brock CK; Wright MK; Byrne CE et al.
Source: Self-asserted source
Courtney B. Lagarde

Multifunctional profiling of triple-negative breast cancer patient-derived tumoroids for disease modeling.

SLAS Discovery : Advancing Life Sciences R & D
2022-02-04 | Journal article
DOI: 10.1016/j.slasd.2022.01.006
PMID: 35124274
Contributors: Cromwell EF; Sirenko O; Nikolov E; Hammer M; Brock CK; Matossian MD; Alzoubi MS; Collins-Burow BM; Burow ME
Source: Self-asserted source
Courtney B. Lagarde

A Role for Adipocytes and Adipose Stem Cells in the Breast Tumor Microenvironment and Regenerative Medicine.

Frontiers in Physiology
2021-11-29 | Journal article
DOI: 10.3389/fphys.2021.751239
PMID: 34912237
PMC: PMC8667576
Contributors: Brock CK; Hebert KL; Artiles M; Wright MK; Cheng T; Gabrielle Windsor; Nguyen K; Alzoubi MS; Collins-Burow BM; Martin EC et al.
Source: Self-asserted source
Courtney B. Lagarde

Constitutive activation of MEK5 promotes a mesenchymal and migratory cell phenotype in triple negative breast cancer.

Oncoscience
2021-05-18 | Journal article
DOI: 10.18632/oncoscience.535
PMID: 34026925
PMC: PMC8131078
Source: Self-asserted source
Courtney B. Lagarde

Stem cell proliferation is induced by apoptotic bodies from dying cells during epithelial tissue maintenance.

Nature Communications
2019-03-05 | Journal article
DOI: 10.1038/s41467-019-09010-6
PMID: 30837472
PMC: PMC6400930
Source: Self-asserted source
Courtney B. Lagarde
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