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Biography

My research aims to gain a better understanding of structure-dynamic-function relationships that underlie cell signaling by human membrane receptors and their molecular partners. To this end, I leverage a combination of NMR with other structural, biophysical and biochemical approaches. My current research interest focuses on signal transduction by immune cell CLRs and GPCRs.

Activities

Employment (4)

Université Toulouse III - Paul Sabatier: Toulouse, FR

2022-09-01 to present | Associate Professor (Maître de Conférences)
Employment
Source: Self-asserted source
Guillaume Ferré

Institute of Pharmacology and Structural Biology: Toulouse, FR

2022-09-01 to present | Associate Professor (Maître de Conférences)
Employment
Source: Self-asserted source
Guillaume Ferré

University of Florida: Gainesville, US

2020-02-24 to 2022-08-29 | Postdoctoral Research Associate (NIH)
Employment
Source: Self-asserted source
Guillaume Ferré

Université Toulouse III - Paul Sabatier: Toulouse, FR

2015-10-01 to 2019-10-31 | PhD student (DCCE, MESR, ANR)
Employment
Source: Self-asserted source
Guillaume Ferré

Education and qualifications (3)

Université Toulouse III - Paul Sabatier: Toulouse, FR

2015 to 2019 | PhD - Biologie Structurale et Fonctionnelle
Education
Source: Self-asserted source
Guillaume Ferré

Université Toulouse III - Paul Sabatier: Toulouse, FR

2013 to 2015 | Master - Biologie Structurale et Fonctionnelle
Education
Source: Self-asserted source
Guillaume Ferré

Université Toulouse III - Paul Sabatier: Toulouse, FR

2010 to 2013 | Licence - Biochimie et Biologie Moléculaire
Education
Source: Self-asserted source
Guillaume Ferré

Works (10)

Development of an In Situ G Protein-Coupled Receptor Fragment Molecule Screening Approach with High-Resolution Magic Angle Spinning Nuclear Magnetic Resonance

ACS Chemical Biology
2025-01-21 | Journal article
Part of ISSN: 1554-8929
Part of ISSN: 1554-8937
Contributors: Enzo Petracco; Guillaume Ferré; Ivo Kabelka; Flavio Ballante; Jens Carlsson; Emma Mulry; Arka P. Ray; James Collins; Florent Allais; Matthew Eddy et al.
Source: Self-asserted source
Guillaume Ferré

Interaction networks within disease-associated GαS variants characterized by an integrative biophysical approach

Journal of Biological Chemistry
2024-08 | Journal article
Contributors: Kara Anazia; Lucien Koenekoop; Guillaume Ferré; Enzo Petracco; Hugo Gutiérrez-de-Terán; Matthew T. Eddy
Source: check_circle
Crossref

Sodium is a negative allosteric regulator of the ghrelin receptor

Cell Reports
2023-04 | Journal article
Part of ISSN: 2211-1247
Contributors: Guillaume Ferré; Antoniel A.S. Gomes; Maxime Louet; Marjorie Damian; Paulo M. Bisch; Olivier Saurel; Nicolas Floquet; Alain Milon; jean-louis Banères
Source: Self-asserted source
Guillaume Ferré

Conserved Protein–Polymer Interactions across Structurally Diverse Polymers Underlie Alterations to Protein Thermal Unfolding

ACS Central Science
2023-03-14 | Journal article
Part of ISSN: 2374-7943
Part of ISSN: 2374-7951
Contributors: Amanda Pritzlaff; Guillaume Ferré; Elia Dargassies; Crystal O. Williams; Daniel D. Gonzalez; Matthew Eddy
Source: Self-asserted source
Guillaume Ferré

Global insights into the fine tuning of human A2AAR conformational dynamics in a ternary complex with an engineered G protein viewed by NMR

Cell Reports
2022-12 | Journal article
Part of ISSN: 2211-1247
Contributors: Guillaume Ferré; Kara Anazia; Larissa O. Silva; Naveen Thakur; Arka P. Ray; Matthew Eddy
Source: Self-asserted source
Guillaume Ferré

Atomic‐Scale View of Protein‐PEG Interactions that Redirect the Thermal Unfolding Pathway of PEGylated Human Galectin‐3

Angewandte Chemie International Edition
2022-10-04 | Journal article
Contributors: Amanda Pritzlaff; Guillaume Ferré; Emma Mulry; Ling Lin; Niloofar Gopal Pour; Daniel A. Savin; Michael E. Harris; Matthew T. Eddy
Source: check_circle
Crossref
grade
Preferred source (of 3)‎

Structural biology of human GPCR drugs and endogenous ligands - insights from NMR spectroscopy

Methods
2020-08 | Journal article
Part of ISSN: 1046-2023
Contributors: Guillaume Ferré; Matthew T. Eddy
Source: Self-asserted source
Guillaume Ferré

Structure and dynamics of dynorphin peptide and its receptor

Opioid Hormones
2019 | Book chapter
Part of ISSN: 0083-6729
Contributors: Guillaume Ferré; Georges Czaplicki; Pascal Demange; Alain Milon
Source: Self-asserted source
Guillaume Ferré

The conical shape of DIM lipids promotes Mycobacterium tuberculosis infection of macrophages

Proceedings of the National Academy of Sciences
2019-12-17 | Journal article
Part of ISSN: 0027-8424
Part of ISSN: 1091-6490
Contributors: Jacques Augenstreich; Evert Haanappel; Guillaume Ferré; Georges Czaplicki; Franck Jolibois; Nicolas Destainville; Christophe Guilhot; Alain MILON; Catherine Astarie-Dequeker; Matthieu Chavent
Source: Self-asserted source
Guillaume Ferré

Structure and dynamics of G protein-coupled receptor–bound ghrelin reveal the critical role of the octanoyl chain

Proceedings of the National Academy of Sciences
2019-08-27 | Journal article
Part of ISSN: 0027-8424
Part of ISSN: 1091-6490
Contributors: Guillaume Ferré; Maxime Louet; Oliver Saurel; Bartholomé Delort; Georges Czaplicki; Céline M’Kadmi; Marjorie Damian; Pedro Renault; Sonia Cantel; Laurent Gavara et al.
Source: Self-asserted source
Guillaume Ferré

Peer review (1 review for 1 publication/grant)

Review activity for Communications biology. (1)