Personal information

electron microscopy, platelet, megakaryocytes, 3D imaging

Activities

Employment (1)

UMR_S1255, Etablissement du Sang du Sang GEST: 10 rue Spielmann 67065 Strasbourg, FR

Researcher EFS
Employment
Source: Self-asserted source
Anita Eckly

Education and qualifications (1)

Université de Strasbourg: Strasbourg, Alsace, FR

PhD, HDR
Education
Source: Self-asserted source
Anita Eckly

Funding (2)

2017-CE14-MEGAPLATPROD

Contract
Agence Nationale de la Recherche (INSERM Grand ESt, FR)
Source: Self-asserted source
Anita Eckly

2022-CE14- MegaPod

Contract
Agence Nationale de la Recherche (Paris, FR)
Source: Self-asserted source
Anita Eckly

Works (50 of 69)

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Page 1 of 2

GPIbα–filamin A interaction regulates megakaryocyte localization and budding during platelet biogenesis

Blood
2024-01-25 | Journal article
Contributors: Marc L. Ellis; Antoine Terreaux; Imala Alwis; Rhyll Smythe; Jose Perdomo; Anita Eckly; Susan L. Cranmer; Freda H. Passam; Jessica Maclean; Simone M. Schoenwaelder et al.
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Crossref

Human platelets do not possess the FcεRI and FcεRII receptors for IgE

Allergy
2023-12 | Journal article
Contributors: Charles Tacquard; Florian Tupin; Stéphanie Magnenat; Nathalie Brouard; Anita Eckly; Fabienne Proamer; Carine Metz‐Favre; Rodolphe Stenger; Anays Piotin; Frédéric De Blay et al.
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Crossref

The fate of mitochondria during platelet activation

Blood Advances
2023-10-24 | Journal article
Contributors: Alexei Grichine; Shancy Jacob; Anita Eckly; Joran Villaret; Clotilde Joubert; Florence Appaix; Mylène Pezet; Anne-Sophie Ribba; Eric Denarier; Jacques Mazzega et al.
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Crossref

Matrix stiffness controls megakaryocyte adhesion, fibronectin fibrillogenesis, and proplatelet formation through Itgβ3

Blood Advances
2023-08-08 | Journal article
Contributors: Ines Guinard; Thao Nguyen; Noémie Brassard-Jollive; Josiane Weber; Laurie Ruch; Laura Reininger; Nathalie Brouard; Anita Eckly; Dominique Collin; François Lanza et al.
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Crossref

Loss of α4A- and β1-tubulins leads to severe platelet spherocytosis and strongly impairs hemostasis in mice

Blood
2022-11-24 | Journal article
Contributors: Quentin Kimmerlin; Sylvie Moog; Alexandra Yakusheva; Catherine Ziessel; Anita Eckly; Monique Freund; Gábor Závodszky; Yannick Knapp; Pierre Mangin; François Lanza
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Crossref

A gain-of-function variant in the Wiskott-Aldrich syndrome gene is associated with a MYH9-related disease-like syndrome

Blood Advances
2022-09-27 | Journal article
Contributors: David Marx; Arnaud Dupuis; Anita Eckly; Anne Molitor; Jérôme Olagne; Guy Touchard; Sihem Kaaki; Cécile Ory; Anne-Laure Faller; Bénédicte Gérard et al.
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Crossref

Traumatic vessel injuries initiating hemostasis generate high shear conditions

Blood Advances
2022-08-23 | Journal article
Contributors: Alexandra A. Yakusheva; Kirill R. Butov; Georgii A. Bykov; Gábor Závodszky; Anita Eckly; Fazly I. Ataullakhanov; Christian Gachet; Mikhail A. Panteleev; Pierre H. Mangin
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Crossref

Blood platelet formation at a glance

Journal of Cell Science
2020-10-15 | Journal article
Contributors: Julie Boscher; Ines Guinard; Anita Eckly; François Lanza; Catherine Léon
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Crossref

Use of electron microscopy to study megakaryocytes

Platelets
2020-07-03 | Journal article
Contributors: Cyril Scandola; Mathieu Erhardt; Jean-Yves Rinckel; Fabienne Proamer; Christian Gachet; Anita Eckly
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Crossref

An essential role for α4A-tubulin in platelet biogenesis.

Life science alliance
2019-02-13 | Journal article
Source: Self-asserted source
Anita Eckly

Clot Contraction Drives the Translocation of Procoagulant Platelets to Thrombus Surface.

Arteriosclerosis, thrombosis, and vascular biology
2019-01-01 | Journal article
Source: Self-asserted source
Anita Eckly

The PI 3-kinase PI3KC2α regulates mouse platelet membrane structure and function independently of membrane lipid composition.

FEBS letters
2018-11-24 | Journal article
Source: Self-asserted source
Anita Eckly

Microtubule plus-end tracking Adenopolyposis Coli negatively regulates proplatelet formation.

Scientific reports
2018-10-25 | Journal article
Source: Self-asserted source
Anita Eckly

High-Resolution 3D Imaging of Megakaryocytes Using Focused Ion Beam-Scanning Electron Microscopy.

Methods in molecular biology (Clifton, N.J.)
2018-01-01 | Journal article
Source: Self-asserted source
Anita Eckly

Macrothrombocytopenia and dense granule deficiency associated with FLI1 variants: ultrastructural and pathogenic features.

Haematologica
2017-03-02 | Journal article
Source: Self-asserted source
Anita Eckly

Respective contributions of single and compound granule fusion to secretion by activated platelets.

Blood
2016-09-13 | Journal article
Source: Self-asserted source
Anita Eckly

Importance of environmental stiffness for megakaryocyte differentiation and proplatelet formation.

Blood
2016-08-08 | Journal article
Source: Self-asserted source
Anita Eckly

Coagulation factors bound to procoagulant platelets concentrate in cap structures to promote clotting.

Blood
2016-07-18 | Journal article
Source: Self-asserted source
Anita Eckly

Lentiviral gene rescue of a Bernard-Soulier mouse model to study platelet glycoprotein Ibβ function.

Journal of thrombosis and haemostasis : JTH
2016-07-14 | Journal article
Source: Self-asserted source
Anita Eckly

Cdc42-dependent F-actin dynamics drive structuration of the demarcation membrane system in megakaryocytes.

Journal of thrombosis and haemostasis : JTH
2016-04-21 | Journal article
Source: Self-asserted source
Anita Eckly

Aryl hydrocarbon receptor-dependent enrichment of a megakaryocytic precursor with a high potential to produce proplatelets.

Blood
2016-03-10 | Journal article
Source: Self-asserted source
Anita Eckly

Time-Dependent Decay of mRNA and Ribosomal RNA during Platelet Aging and Its Correlation with Translation Activity.

PloS one
2016-01-25 | Journal article
Source: Self-asserted source
Anita Eckly

Dehydration of blood platelets by zeodration: in vitro characterization and hemostatic properties in vivo.

Transfusion
2015-04-09 | Journal article
Source: Self-asserted source
Anita Eckly

Distinct localizations and roles of non-muscle myosin II during proplatelet formation and platelet release.

Journal of thrombosis and haemostasis : JTH
2015-04-01 | Journal article
Source: Self-asserted source
Anita Eckly

The class II PI 3-kinase, PI3KC2α, links platelet internal membrane structure to shear-dependent adhesive function.

Nature communications
2015-03-17 | Journal article
Source: Self-asserted source
Anita Eckly

Broader expression of the mouse platelet factor 4-cre transgene beyond the megakaryocyte lineage.

Journal of thrombosis and haemostasis : JTH
2014-12-17 | Journal article
Source: Self-asserted source
Anita Eckly

FLow-induced PRotrusions (FLIPRs): a platelet-derived platform for the retrieval of microparticles by monocytes and neutrophils.

Circulation research
2014-01-09 | Journal article
Source: Self-asserted source
Anita Eckly

Myosin IIA is critical for organelle distribution and F-actin organization in megakaryocytes and platelets.

Blood
2013-11-15 | Journal article
Source: Self-asserted source
Anita Eckly

Biogenesis of the demarcation membrane system (DMS) in megakaryocytes.

Blood
2013-10-23 | Journal article
Source: Self-asserted source
Anita Eckly

Defective tubulin organization and proplatelet formation in murine megakaryocytes lacking Rac1 and Cdc42.

Blood
2013-07-16 | Journal article
Source: Self-asserted source
Anita Eckly

Integrin α6β1 is the main receptor for vascular laminins and plays a role in platelet adhesion, activation, and arterial thrombosis.

Circulation
2013-07-01 | Journal article
Source: Self-asserted source
Anita Eckly

Birbeck granule-like "organized smooth endoplasmic reticulum" resulting from the expression of a cytoplasmic YFP-tagged langerin.

PloS one
2013-04-05 | Journal article
Source: Self-asserted source
Anita Eckly

Targeting platelet GPIbβ reduces platelet adhesion, GPIb signaling and thrombin generation and prevents arterial thrombosis.

Arteriosclerosis, thrombosis, and vascular biology
2013-04-04 | Journal article
Source: Self-asserted source
Anita Eckly

Preserved functional and biochemical characteristics of platelet components prepared with amotosalen and ultraviolet A for pathogen inactivation.

Transfusion
2012-10-15 | Journal article
Source: Self-asserted source
Anita Eckly

Romiplostim administration shows reduced megakaryocyte response-capacity and increased myelofibrosis in a mouse model of MYH9-RD.

Blood
2012-01-10 | Journal article
Source: Self-asserted source
Anita Eckly

Characterization of megakaryocyte development in the native bone marrow environment.

Methods in molecular biology (Clifton, N.J.)
2012-01-01 | Journal article
Source: Self-asserted source
Anita Eckly

Hirudin and heparin enable efficient megakaryocyte differentiation of mouse bone marrow progenitors.

Experimental cell research
2011-10-08 | Journal article
Source: Self-asserted source
Anita Eckly

Mechanisms underlying FeCl3-induced arterial thrombosis.

Journal of thrombosis and haemostasis : JTH
2011-04-01 | Journal article
Source: Self-asserted source
Anita Eckly

Immature myeloid dendritic cells capture and remove activated platelets from preformed aggregates.

Journal of thrombosis and haemostasis : JTH
2010-10-01 | Journal article
Source: Self-asserted source
Anita Eckly

Proplatelet formation deficit and megakaryocyte death contribute to thrombocytopenia in Myh9 knockout mice.

Journal of thrombosis and haemostasis : JTH
2010-10-01 | Journal article
Source: Self-asserted source
Anita Eckly

ADF/n-cofilin-dependent actin turnover determines platelet formation and sizing.

Blood
2010-06-07 | Journal article
Source: Self-asserted source
Anita Eckly

Multiple alterations of platelet functions dominated by increased secretion in mice lacking Cdc42 in platelets.

Blood
2010-02-04 | Journal article
Source: Self-asserted source
Anita Eckly

Arterial thrombosis: relevance of a model with two levels of severity assessed by histologic, ultrastructural and functional characterization.

Journal of thrombosis and haemostasis : JTH
2009-10-24 | Journal article
Source: Self-asserted source
Anita Eckly

The platelet glycoprotein GPIbbeta intracellular domain participates in von Willebrand factor induced-filopodia formation independently of the Ser 166 phosphorylation site.

Journal of thrombosis and haemostasis : JTH
2009-08-19 | Journal article
Source: Self-asserted source
Anita Eckly

Intrinsic impaired proplatelet formation and microtubule coil assembly of megakaryocytes in a mouse model of Bernard-Soulier syndrome.

Haematologica
2009-04-18 | Journal article
Source: Self-asserted source
Anita Eckly

Abnormal megakaryocyte morphology and proplatelet formation in mice with megakaryocyte-restricted MYH9 inactivation.

Blood
2008-11-04 | Journal article
Source: Self-asserted source
Anita Eckly

Megakaryocyte-restricted MYH9 inactivation dramatically affects hemostasis while preserving platelet aggregation and secretion.

Blood
2007-07-30 | Journal article
Source: Self-asserted source
Anita Eckly

Inhibition of adhesive and signaling functions of the platelet GPIb-V-IX complex by a cell penetrating GPIbalpha peptide.

Journal of thrombosis and haemostasis : JTH
2006-12-01 | Journal article
Source: Self-asserted source
Anita Eckly

Decreased thrombotic tendency in mouse models of the Bernard-Soulier syndrome.

Arteriosclerosis, thrombosis, and vascular biology
2006-11-09 | Journal article
Source: Self-asserted source
Anita Eckly

Synthesis of GPIb beta with novel transmembrane and cytoplasmic sequences in a Bernard-Soulier patient resulting in GPIb-defective signaling in CHO cells.

Journal of thrombosis and haemostasis : JTH
2006-01-01 | Journal article
Source: Self-asserted source
Anita Eckly
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