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ResearcherID: J-5826-2012
Loop profile: 181817
Scopus Author ID: 56527228000
Scopus Author ID: 57172965000
Scopus Author ID: 57219824840

Keywords

Biomedical Optics, Medical Imaging

Countries

India, United States

Activities

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Employment (2)

Shell: Bengaluru, Karnataka, IN

2023-01-09 to present | Research Geophysicst (Inversion and Imaging)
Employment
Source: Self-asserted source
Rakesh Manjappa

Stanford University: Stanford, CA, US

2019-02-14 to 2023-12-02 | Postdoctoral Scholar (Radiation Oncology)
Employment
Source: Self-asserted source
Rakesh Manjappa

Education and qualifications (2)

Indian Institute of Science: Bangalore, KA, IN

2011-08-01 to present | PhD (Physics)
Education
Source: Self-asserted source
Rakesh Manjappa

Indian Institute of Technology Delhi: New Delhi, DL, IN

2007-08-01 to 2011-07-31 | Bachelor of Technology in Engineering Physics (Physics)
Education
Source: Self-asserted source
Rakesh Manjappa

Professional activities (4)

SPIE: Bellingham, WA, US

Membership
Source: Self-asserted source
Rakesh Manjappa

Optical Society of America: Washington, DC, US

Membership
Source: Self-asserted source
Rakesh Manjappa

IEEE: New York, NY, US

Membership
Source: Self-asserted source
Rakesh Manjappa

European SocieTy for Radiotherapy and Oncology: Brussels, BE

Membership
Source: Self-asserted source
Rakesh Manjappa

Funding (2)

SPIE Chapter Officer Travel Grant

2015-08 to 2015-08 | Grant
SPIE (WA, WA, US)
Source: Self-asserted source
Rakesh Manjappa

Senior Research Fellow

2013-07 to 2016-07 | Salary award
Indian Institute of Science (Bangalore, IN)
Source: Self-asserted source
Rakesh Manjappa

Works (37)

A multi-institutional study to investigate the sparing effect after whole brain electron FLASH in mice: Reproducibility and temporal evolution of functional, electrophysiological, and neurogenic endpoints

Radiotherapy and Oncology
2024 | Journal article
DOI: 10.1016/j.radonc.2024.110534
EID:

2-s2.0-85205974273

Part of ISSN: 18790887 01678140
Contributors: Drayson, O.G.G.; Melemenidis, S.; Katila, N.; Viswanathan, V.; Kramár, E.A.; Zhang, R.; Kim, R.; Ru, N.; Petit, B.; Dutt, S. et al.
Source: Self-asserted source
Rakesh Manjappa via Scopus - Elsevier

Dosimetric calibration of anatomy-specific ultra-high dose rate electron irradiation platform for preclinical FLASH radiobiology experiments

Medical Physics
2024 | Journal article
DOI: 10.1002/mp.17432
EID:

2-s2.0-85205081941

Part of ISSN: 24734209 00942405
Contributors: Wang, J.; Melemenidis, S.; Manjappa, R.; Viswanathan, V.; Ashraf, R.M.; Levy, K.; Skinner, L.B.; Soto, L.A.; Chow, S.; Lau, B. et al.
Source: Self-asserted source
Rakesh Manjappa via Scopus - Elsevier

Exploring Deep Learning for Estimating the Isoeffective Dose of FLASH Irradiation From Mouse Intestinal Histological Images

International Journal of Radiation Oncology Biology Physics
2024 | Journal article
DOI: 10.1016/j.ijrobp.2023.12.032
EID:

2-s2.0-85184056652

Part of ISSN: 1879355X 03603016
Contributors: Fu, J.; Yang, Z.; Melemenidis, S.; Viswanathan, V.; Dutt, S.; Manjappa, R.; Lau, B.; Soto, L.A.; Ashraf, M.R.; Skinner, L. et al.
Source: Self-asserted source
Rakesh Manjappa via Scopus - Elsevier
grade
Preferred source (of 2)‎

FULL TITLE: A multi-institutional study to investigate the sparing effect after whole brain electron FLASH in mice: Reproducibility and temporal evolution of functional, electrophysiological, and neurogenic endpoints

bioRxiv
2024 | Other
DOI: 10.1101/2024.01.25.577164
EID:

2-s2.0-85184312045

Part of ISSN: 26928205
Contributors: Drayson, O.G.G.; Melemenidis, S.; Katila, N.; Viswanathan, V.; Kramár, E.A.; Zhang, R.; Kim, R.; Ru, N.; Petit, B.; Dutt, S. et al.
Source: Self-asserted source
Rakesh Manjappa via Scopus - Elsevier
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Preferred source (of 2)‎

Multi-Institutional Audit of FLASH and Conventional Dosimetry With a 3D Printed Anatomically Realistic Mouse Phantom

International Journal of Radiation Oncology Biology Physics
2024 | Journal article
DOI: 10.1016/j.ijrobp.2024.03.017
EID:

2-s2.0-85190511383

Part of ISSN: 1879355X 03603016
Contributors: Ashraf, M.R.; Melemenidis, S.; Liu, K.; Grilj, V.; Jansen, J.; Velasquez, B.; Connell, L.; Schulz, J.B.; Bailat, C.; Libed, A. et al.
Source: Self-asserted source
Rakesh Manjappa via Scopus - Elsevier

Effectiveness of FLASH vs conventional dose rate radiotherapy in a model of orthotopic, murine breast cancer

2024-12-17 | Preprint
DOI: 10.1101/2024.12.14.628467
Contributors: Stavros Melemenidis; Vignesh Viswanathan; Suparna Dutt; Rakesh Manjappa; Naviya Kapadia; Brianna Lau; Luis A. Soto; Ramish M. Ashraf; Banita Thakur; Adel Z. I. Mutahar et al.
Source: check_circle
Crossref
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Rapid Sterilization of Clinical Apheresis Blood Products using Ultra-High Dose Rate Radiation

2024-12-14 | Preprint
DOI: 10.1101/2024.12.14.628469
Contributors: Stavros Melemenidis; Khoa D. Nguyen; Rosella Baraceros-Pineda; Cherie K. Barclay; Joanne Bautista; Hubert Lau; M. Ramish Ashraf; Rakesh Manjappa; Suparna Dutt; Luis Armando Soto et al.
Source: check_circle
Crossref
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Preferred source (of 2)‎

Clinical Linear Accelerator-Based Electron FLASH: Pathway for Practical Translation to FLASH Clinical Trials

International Journal of Radiation Oncology Biology Physics
2023 | Journal article
DOI: 10.1016/j.ijrobp.2023.04.011
EID:

2-s2.0-85160068566

Part of ISSN: 1879355X 03603016
Contributors: No, H.J.; Wu, Y.F.; Dworkin, M.L.; Manjappa, R.; Skinner, L.; Ashraf, M.R.; Lau, B.; Melemenidis, S.; Viswanathan, V.; Yu, A.S.-J. et al.
Source: Self-asserted source
Rakesh Manjappa via Scopus - Elsevier
grade
Preferred source (of 2)‎

Determination of Electron Beam Parameters using Nelder-Mead Simplex Search Algorithm

Transactions of the American Nuclear Society
2023 | Conference paper
DOI: 10.13182/T128-42111
EID:

2-s2.0-85180626650

Part of ISSN: 0003018X
Contributors: Rosenstrom, A.; Santana, M.; Rokni, S.; Dewji, S.; Ashraf, R.; Melemenidis, S.; Manjappa, R.; Loo, B.W.
Source: Self-asserted source
Rakesh Manjappa via Scopus - Elsevier

Dosimetric calibration of an anatomically specific ultra-high dose rate electron irradiation platform for preclinical FLASH radiobiology experiments

arXiv
2023 | Other
DOI: 10.48550/arXiv.2312.10632
EID:

2-s2.0-85180611915

Part of ISSN: 23318422
Contributors: Wang, J.; Melemenidis, S.; Manjappa, R.; Viswanathan, V.; Ashraf, R.M.; Levy, K.; Skinner, L.; Soto, L.A.; Chow, S.; Lau, B. et al.
Source: Self-asserted source
Rakesh Manjappa via Scopus - Elsevier

FLASH-RT does not affect chromosome translocations and junction structures beyond that of CONV-RT dose-rates

bioRxiv
2023 | Other
DOI: 10.1101/2023.03.27.534408
EID:

2-s2.0-85159431686

Part of ISSN: 26928205
Contributors: Barghouth, P.G.; Melemenidis, S.; Montay-Gruel, P.; Ollivier, J.; Viswanathan, V.; Jorge, P.G.; Soto, L.A.; Lau, B.C.; Sadeghi, C.; Edlabadkar, A. et al.
Source: Self-asserted source
Rakesh Manjappa via Scopus - Elsevier
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FLASH-RT does not affect chromosome translocations and junction structures beyond that of CONV-RT dose-rates

Radiotherapy and Oncology
2023 | Journal article
DOI: 10.1016/j.radonc.2023.109906
EID:

2-s2.0-85171653635

Part of ISSN: 18790887 01678140
Contributors: Barghouth, P.G.; Melemenidis, S.; Montay-Gruel, P.; Ollivier, J.; Viswanathan, V.; Jorge, P.G.; Soto, L.A.; Lau, B.C.; Sadeghi, C.; Edlabadkar, A. et al.
Source: Self-asserted source
Rakesh Manjappa via Scopus - Elsevier
grade
Preferred source (of 2)‎

Human enteroids as a tool to study conventional and ultra-high dose rate radiation

Integrative Biology
2023 | Journal article
DOI: 10.1093/intbio/zyad013
EID:

2-s2.0-85175356905

Part of ISSN: 17579708 17579694
Contributors: Klett, K.C.; Martin-Villa, B.C.; Villarreal, V.S.; Melemenidis, S.; Viswanathan, V.; Manjappa, R.; Ashraf, M.R.; Soto, L.; Lau, B.; Dutt, S. et al.
Source: Self-asserted source
Rakesh Manjappa via Scopus - Elsevier
grade
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Multi-Institutional Audit of FLASH and Conventional Dosimetry with a 3D-Printed Anatomically Realistic Mouse Phantom

arXiv
2023 | Other
DOI: 10.48550/arXiv.2309.16836
EID:

2-s2.0-85174791272

Part of ISSN: 23318422
Contributors: Ashraf, M.R.; Melemenidis, S.; Liu, K.; Grilj, V.; Jansen, J.; Velasquez, B.; Connell, L.; Schulz, J.B.; Bailat, C.; Libed, A. et al.
Source: Self-asserted source
Rakesh Manjappa via Scopus - Elsevier

Abdominopelvic FLASH Irradiation Improves PD-1 Immune Checkpoint Inhibition in Preclinical Models of Ovarian Cancer

Molecular Cancer Therapeutics
2022 | Journal article
DOI: 10.1158/1535-7163.MCT-21-0358
EID:

2-s2.0-85124438315

Part of ISSN: 15388514 15357163
Contributors: Eggold, J.T.; Chow, S.; Melemenidis, S.; Wang, J.; Natarajan, S.; Loo, P.E.; Manjappa, R.; Viswanathan, V.; Kidd, E.A.; Engleman, E. et al.
Source: Self-asserted source
Rakesh Manjappa via Scopus - Elsevier
grade
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Design and validation of a dosimetric comparison scheme tailored for ultra-high dose-rate electron beams to support multicenter FLASH preclinical studies

Radiotherapy and Oncology
2022 | Journal article
DOI: 10.1016/j.radonc.2022.08.023
EID:

2-s2.0-85137380330

Part of ISSN: 18790887 01678140
Contributors: Jorge, P.G.; Melemenidis, S.; Grilj, V.; Buchillier, T.; Manjappa, R.; Viswanathan, V.; Gondré, M.; Vozenin, M.-C.; Germond, J.-F.; Bochud, F. et al.
Source: Self-asserted source
Rakesh Manjappa via Scopus - Elsevier
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Real-time optical oximetry during FLASH radiotherapy using a phosphorescent nanoprobe

Radiotherapy and Oncology
2022 | Journal article
DOI: 10.1016/j.radonc.2022.08.011
EID:

2-s2.0-85136295325

Part of ISSN: 18790887 01678140
Contributors: Ha, B.; Liang, K.; Liu, C.; Melemenidis, S.; Manjappa, R.; Viswanathan, V.; Das, N.; Ashraf, R.; Lau, B.; Soto, L. et al.
Source: Self-asserted source
Rakesh Manjappa via Scopus - Elsevier
grade
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Multicellular Spheroids as In Vitro Models of Oxygen Depletion During FLASH Irradiation

International Journal of Radiation Oncology Biology Physics
2021 | Journal article
DOI: 10.1016/j.ijrobp.2021.01.050
EID:

2-s2.0-85102070574

Part of ISSN: 1879355X 03603016
Contributors: Khan, S.; Bassenne, M.; Wang, J.; Manjappa, R.; Melemenidis, S.; Breitkreutz, D.Y.; Maxim, P.G.; Xing, L.; Loo, B.W.; Pratx, G.
Source: Self-asserted source
Rakesh Manjappa via Scopus - Elsevier

Feasibility of Clinically Practical Ultra-High Dose Rate (FLASH) Radiation Delivery by a Reversible Configuration of a Standard Clinical-Use Linear Accelerator.

International journal of radiation oncology, biology, physics
2021-11 | Journal article
DOI: 10.1016/j.ijrobp.2021.07.099
PMID: 34700535
Contributors: No HJ; Wu YF; Manjappa R; Skinner L; Lau B; Melemenidis S; Yu SJ; Surucu M; Schueler E; Bush K et al.
Source: Self-asserted source
Rakesh Manjappa via Europe PubMed Central

Validation of a Novel Cone-Less Set-up for Electron FLASH Radiation Delivery on a Clinical-Use Linear Accelerator.

International journal of radiation oncology, biology, physics
2021-11 | Journal article
DOI: 10.1016/j.ijrobp.2021.07.314
PMID: 34700478
Contributors: Wu YF; No HJ; Manjappa R; Skinner L; Yu SJ; Lau B; Surucu M; Schueler E; Bush K; Graves EE et al.
Source: Self-asserted source
Rakesh Manjappa via Europe PubMed Central

Abdominal FLASH irradiation reduces radiation-induced gastrointestinal toxicity for the treatment of ovarian cancer in mice

Scientific Reports
2020 | Journal article
DOI: 10.1038/s41598-020-78017-7
EID:

2-s2.0-85097390802

Part of ISSN: 20452322
Contributors: Levy, K.; Natarajan, S.; Wang, J.; Chow, S.; Eggold, J.T.; Loo, P.E.; Manjappa, R.; Melemenidis, S.; Lartey, F.M.; Schüler, E. et al.
Source: Self-asserted source
Rakesh Manjappa via Scopus - Elsevier

FLASH Irradiation Of Avascular Tumor Spheroids

International Journal of Radiation Oncology*Biology*Physics
2020-11 | Journal article
DOI: 10.1016/j.ijrobp.2020.07.1728
Part of ISSN: 0360-3016
Contributors: S. Khan; M. Bassenne; J. Wang; R. Manjappa; B.W. Loo; G. Pratx
Source: Self-asserted source
Rakesh Manjappa via Crossref Metadata Search

Combination total abdominal ultra-rapid flash irradiation and PD-1 inhibition provides enhanced tumor burden control in a preclinical ovarian cancer model

Gynecologic Oncology
2020-10 | Journal article
DOI: 10.1016/j.ygyno.2020.05.102
Part of ISSN: 0090-8258
Contributors: S. Chow; J. Eggold; K. Levy; J. Wang; R. Manjappa; O. Dorigo; B. Loo; E. Rankin
Source: Self-asserted source
Rakesh Manjappa via Crossref Metadata Search

Abstract 5351: FLASH irradiation enhances the therapeutic index of abdominal radiotherapy in mice

Experimental and Molecular Therapeutics
2020-08 | Other
DOI: 10.1158/1538-7445.am2020-5351
Contributors: Suchitra Natarajan; Karen Levy; Jinghui Wang; Stephanie Chow; Joshua Eggold; Phoebe Loo; Rakesh Manjappa; Frederick M. Lartey; Emil Schüler; Lawrie Skinner et al.
Source: Self-asserted source
Rakesh Manjappa via Crossref Metadata Search

Abstract 5357: Total abdominal ultra-rapid FLASH irradiation enhances the efficacy of PD-1 inhibition in preclinical models of ovarian cancer

Experimental and Molecular Therapeutics
2020-08 | Other
DOI: 10.1158/1538-7445.am2020-5357
Contributors: Stephanie Chow; Joshua T. Eggold; Karen Levy; Jinghui Wang; Rakesh Manjappa; Dylan Y. Breitkreutz; Amy S. Yu; Karl Bush; Oliver Dorigo; Billy W. Loo et al.
Source: Self-asserted source
Rakesh Manjappa via Crossref Metadata Search

FLASH Irradiation Results in Reduced Severe Skin Toxicity Compared to Conventional-Dose-Rate Irradiation.

Radiation research
2020-08 | Journal article
DOI: 10.1667/rade-20-00090
PMID: 32853385
Contributors: Soto LA; Casey KM; Wang J; Blaney A; Manjappa R; Breitkreutz D; Skinner L; Dutt S; Ko RB; Bush K et al.
Source: Self-asserted source
Rakesh Manjappa via Europe PubMed Central
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FLASH irradiation enhances the therapeutic index of abdominal radiotherapy in mice

bioRxiv
2019 | Other
DOI: 10.1101/2019.12.12.873414
EID:

2-s2.0-85095642220

Part of ISSN: 26928205
Contributors: Levy, K.; Natarajan, S.; Wang, J.; Chow, S.; Eggold, J.; Loo, P.; Manjappa, R.; Lartey, F.M.; Schüler, E.; Skinner, L. et al.
Source: Self-asserted source
Rakesh Manjappa via Scopus - Elsevier
grade
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Depth Sensitivity Improvement of Region-of-Interest Diffuse Optical Tomography from Superficial Signal Regression

Imaging and Applied Optics 2018 (3D, AO, AIO, COSI, DH, IS, LACSEA, LS&C, MATH, pcAOP)
2018 | Conference paper
DOI: 10.1364/cosi.2018.cm3e.5
Part of ISBN: 9781943580446
Contributors: Manob Jyoti Saikia; Rakesh Manjappa; Kunal Mankodiya; Rajan Kanhirodan
Source: Self-asserted source
Rakesh Manjappa via Crossref Metadata Search
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Fluence calculation using portal images

Imaging and Applied Optics 2018 (3D, AO, AIO, COSI, DH, IS, LACSEA, LS&C, MATH, pcAOP)
2018 | Conference paper
DOI: 10.1364/3d.2018.jw4a.35
Part of ISBN: 9781943580446
Contributors: Rakesh Manjappa; Vyankatesh Shejal; Rajesh Kumar; Rajan Kanhirodan
Source: Self-asserted source
Rakesh Manjappa via Crossref Metadata Search
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A cost-effective LED and photodetector based fast direct 3D diffuse optical imaging system

Diffuse Optical Spectroscopy and Imaging VI
2017-07 | Conference paper
DOI: 10.1117/12.2285940
Contributors: Manob Jyoti Saikia; Rakesh Manjappa; Rajan Kanhirodan; Hamid Dehghani; Heidrun Wabnitz
Source: Self-asserted source
Rakesh Manjappa via Crossref Metadata Search
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Correction of refraction distortion due to boundary mismatch in optical ct of gel dosimeters

Biomedical Optics 2016
2016 | Conference paper
DOI: 10.1364/cancer.2016.jw3a.2
Contributors: Rakesh Manjappa; Sharath M. Shankaranarayana; Rajesh Kumar; Ram M. Vasu; Rajan Kanhirodan
Source: Self-asserted source
Rakesh Manjappa via Crossref Metadata Search
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Fully 3D refraction correction dosimetry system

Phys. Med. Biol.
2016-02-03 | Journal article
DOI: 10.1088/0031-9155/61/4/1722
Contributors: Rakesh Manjappa; S Sharath Makki; Rajesh Kumar; Ram Mohan Vasu; Rajan Kanhirodan
Source: Self-asserted source
Rakesh Manjappa via Crossref Metadata Search
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Ray tracing based path-length calculations for polarized light tomographic imaging

Polarization Science and Remote Sensing VII
2015-09-01 | Conference paper
DOI: 10.1117/12.2189190
Contributors: Rakesh Manjappa; Rajan Kanhirodan; Joseph A. Shaw; Daniel A. LeMaster
Source: Self-asserted source
Rakesh Manjappa via Crossref Metadata Search
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Effects of refractive index mismatch in optical CT imaging of polymer gel dosimeters

Med. Phys.
2015-02 | Journal article
DOI: 10.1118/1.4905043
Contributors: Rakesh Manjappa; Sharath Makki S; Rajesh Kumar; Rajan Kanhirodan
Source: Self-asserted source
Rakesh Manjappa via Crossref Metadata Search
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Polarized light Monte Carlo modeling for multiparticle distribution of scatterers

12th International Conference on Fiber Optics and Photonics
2014 | Conference paper
DOI: 10.1364/photonics.2014.s5a.2
Contributors: Rakesh Manjappa; Chinmaya Devaraj; Sharath N S; Rajat Hebbar; Sharath M. Shankaranarayana; Rajan Kanhirodan
Source: Self-asserted source
Rakesh Manjappa via Crossref Metadata Search
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Polarized light Monte Carlo simulations of Depolarization contrast from Gold Nanoparticles

Biomedical Optics 2014
2014 | Conference paper
DOI: 10.1364/biomed.2014.bs3a.51
Contributors: Rakesh Manjappa; Sharath M. Shankaranarayana; Rajan Kanhirodan
Source: Self-asserted source
Rakesh Manjappa via Crossref Metadata Search

Sparse Recovery Methods Hold Promise for Diffuse Optical Tomographic Image Reconstruction

IEEE J. Select. Topics Quantum Electron.
Journal article
DOI: 10.1109/jstqe.2013.2278218
Contributors: Jaya Prakash; Calvin B. Shaw; Rakesh Manjappa; Rajan Kanhirodan; Phaneendra K. Yalavarthy
Source: Self-asserted source
Rakesh Manjappa via Crossref Metadata Search
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Peer review (40 reviews for 13 publications/grants)

Review activity for AIP advances. (2)
Review activity for Applied optics. (9)
Review activity for Biomedical optics express. (3)
Review activity for Current Science. (1)
Review activity for IEEE journal of selected topics in quantum electronics : (3)
Review activity for IEEE photonics journal. (2)
Review activity for IEEE transactions on image processing : (5)
Review activity for Journal of lightwave technology : (1)
Review activity for Journal of the Optical Society of America. (6)
Review activity for Optics letters. (4)
Review activity for Procedia computer science. (1)
Review activity for Proceedings of IEEE Sensors / (1)
Review activity for Review of scientific instruments online. (2)
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