Personal information

Germany

Activities

Employment (1)

University of Lübeck: Lübeck, Schleswig-Holstein, DE

2021-11-01 to present | Professor (Department of Dermatology)
Employment
Source: Self-asserted source
MH Hoffmann

Funding (11)

Metabolic and dietary control of inflammatory tissue priming and arthritis

2022-04 to 2025-03 | Grant
Deutsche Forschungsgemeinschaft (Bonn, DE)
Part of GRANT_NUMBER:

FOR2886-B04/2 "PANDORA"

Source: Self-asserted source
MH Hoffmann

Development of “smart” amplifiers of reactive oxygen species specific to aberrant polymorphonuclear neutrophils for treatment of inflammatory and autoimmune diseases, cancer and myeloablation (NeutroCure).

2020-01 to 2025-01 | Grant
European Commission (Bruxelles, BE)
Part of GRANT_NUMBER:

H2020-FETOPEN-2018-2019-2020-01; 861878

Source: Self-asserted source
MH Hoffmann

Amplification of NET Formation and Neutrophil Aggregation for the Resolution of Inflammation

2019-07 to 2023-07 | Grant
Deutsche Forschungsgemeinschaft (Bonn, DE)
Part of GRANT_NUMBER: CRC1181/2-C03
Source: Self-asserted source
MH Hoffmann

Immunometabolic Checkpoints within Synovial Fibroblasts in Rheumatoid Arthritis

2019-04 to 2022-03 | Grant
Deutsche Forschungsgemeinschaft (Bonn, DE)
GRANT_NUMBER:

HO 5193/4-1

Source: Self-asserted source
MH Hoffmann

The importance of Neutrophil extracellular traps for the resolution of neutrophil-driven inflammation

2015-07 to 2019-06 | Grant
Deutsche Forschungsgemeinschaft (Bonn, DE)
GRANT_NUMBER:

CRC1181/1-C03

Source: Self-asserted source
MH Hoffmann

REDOXIT

2015-06 to 2017-04 | Grant
European Commission (Brussels, BE)
GRANT_NUMBER:

H2020-MSCA-RISE-2014

Source: Self-asserted source
MH Hoffmann

Die Rolle des oxidativen Burst im systemischen Lupus erythematosus

2014-04 to 2015-04 | Grant
Staedtler-Stiftung (Nürnberg, DE)
GRANT_NUMBER:

DS/eH 02/14

Source: Self-asserted source
MH Hoffmann

The role of the oxidative burst in bone remodelling during inflammation

2013-06 to 2016-05 | Grant
DFG (Bonn, DE)
GRANT_NUMBER: HO 5193/1-1
Source: Self-asserted source
MH Hoffmann

The role of cathelicidins in lupus and arthritis

2012-10 to 2013-09 | Grant
ELAN Fonds (Erlangen, DE)
GRANT_NUMBER:

12-03-07-01-Hoffmann

Source: Self-asserted source
MH Hoffmann

The role of anti-microbial peptides in the development of rheumatoid arthritis and systemic lupus erythematosus

2010-11 to present | Grant
Stiftelsen Lars Hiertas Minne (Stockholm, SE)
Source: Self-asserted source
MH Hoffmann

Integration of the concepts of endogenously released nucleic acids, oxidation deficiencies and anti-microbial peptides for explaining the development of autoimmune diseases

Grant
Austrian Science fund (FWF) (Vienna, AT)
Source: Self-asserted source
MH Hoffmann

Works (50 of 57)

Items per page:
Page 1 of 2

Meeting Report on “10th Anniversary Symposium on Inflammatory Skin Disease”

JID Innovations
2025-05 | Journal article
Contributors: Shirin Emtenani; John F. Baines; Katja Bieber; Evelyn Gaffal; Stephanie Goletz; Gema Hernández; Misa Hirose; Markus Hoffmann; Pascal Joly; Henriette Kirchner et al.
Source: check_circle
Crossref

Inflammatory tissue priming: novel insights and therapeutic opportunities for inflammatory rheumatic diseases

Annals of the Rheumatic Diseases
2024-10 | Journal article
Contributors: Markus H Hoffmann; Henriette Kirchner; Gerhard Krönke; Gabriela Riemekasten; Michael Bonelli
Source: check_circle
Crossref

Reset of inflammatory priming of joint tissue and reduction of the severity of arthritis flares by bromodomain inhibition.

Arthritis & rheumatology (Hoboken, N.J.)
2022-10-17 | Journal article | Author
Contributors: Friščić J; Reinwald C; Böttcher M; Houtman M; Euler M; Chen X; Walker KI; Kirchner P; Honglin ZHU; Wirth B et al.
Source: Self-asserted source
MH Hoffmann

Targeting the tissue-complosome for curbing inflammatory disease.

Seminars in immunology
2022-07-25 | Journal article
Contributors: MH Hoffmann; Dutta K; Friscic J; Hoffmann MH
Source: Self-asserted source
MH Hoffmann

Neutrophils prevent rectal bleeding in ulcerative colitis by peptidyl-arginine deiminase-4-dependent immunothrombosis.

Gut
2021-12-03 | Journal article
Contributors: MH Hoffmann; Moritz Leppkes; Lindemann A; Gößwein S; Paulus S; Roth D; Hartung A; Liebing E; Sebastian Zundler; Gonzalez-Acera M et al.
Source: Self-asserted source
MH Hoffmann

Patients with COVID-19: in the dark-NETs of neutrophils

Cell Death & Differentiation
2021-11 | Journal article
Contributors: Maximilian Ackermann; Hans-Joachim Anders; Rostyslav Bilyy; Gary L. Bowlin; Christoph Daniel; Rebecca De Lorenzo; Mikala Egeblad; Timo Henneck; Andrés Hidalgo; Markus Hoffmann et al.
Source: check_circle
Crossref

Stromal cell regulation of inflammatory responses.

Current opinion in immunology
2021-11-27 | Journal article
Contributors: MH Hoffmann; Friščić J; Hoffmann MH
Source: Self-asserted source
MH Hoffmann

Dietary Derived Propionate Regulates Pathogenic Fibroblast Function and Ameliorates Experimental Arthritis and Inflammatory Tissue Priming.

Nutrients
2021-05-13 | Journal article
Source: Self-asserted source
MH Hoffmann

The complement system drives local inflammatory tissue priming by metabolic reprogramming of synovial fibroblasts.

Immunity
2021-03-19 | Journal article
Source: Self-asserted source
MH Hoffmann

'SMASH' recommendations for standardised microscopic arthritis scoring of histological sections from inflammatory arthritis animal models.

Annals of the rheumatic diseases
2021-02-18 | Journal article
Source: Self-asserted source
MH Hoffmann

Stromal-driven and Amyloid β-dependent induction of neutrophil extracellular traps modulates tumor growth

Nature Communications
2020-12 | Journal article
Source: Self-asserted source
MH Hoffmann
grade
Preferred source (of 2)‎

Myeloperoxidase Modulates Inflammation in Generalized Pustular Psoriasis and Additional Rare Pustular Skin Diseases.

American journal of human genetics
2020-08-05 | Journal article
Source: Self-asserted source
MH Hoffmann

Therapeutic ACPA inhibits NET formation: a potential therapy for neutrophil-mediated inflammatory diseases.

Cellular & molecular immunology
2020-03-20 | Journal article
Source: Self-asserted source
MH Hoffmann

IgA subclasses have different effector functions associated with distinct glycosylation profiles.

Nature communications
2020-01-08 | Journal article
Source: Self-asserted source
MH Hoffmann

The double-edged role of neutrophil extracellular traps in inflammation.

Biochemical Society transactions
2019-12-01 | Journal article
Source: Self-asserted source
MH Hoffmann
grade
Preferred source (of 2)‎

Neutrophil Extracellular Traps Initiate Gallstone Formation.

Immunity
2019-08-15 | Journal article
Source: Self-asserted source
MH Hoffmann

NOX2 mediates quiescent handling of dead cell remnants in phagocytes.

Redox biology
2019-07-20 | Journal article
Source: Self-asserted source
MH Hoffmann

To NET or not to NET:current opinions and state of the science regarding the formation of neutrophil extracellular traps.

2019-03 | Journal article
Source: Self-asserted source
MH Hoffmann

Aggregated neutrophil extracellular traps resolve inflammation by proteolysis of cytokines and chemokines and protection from antiproteases

FASEB Journal
2019-01 | Journal article
Source: Self-asserted source
MH Hoffmann

Lenalidomide enhances MOR202 dependent macrophage-mediated effector functions via the vitamin D pathway

Leukemia
2018-11 | Journal article
Source: Self-asserted source
MH Hoffmann

The dual role of Reactive Oxygen Species in autoimmune and inflammatory diseases: evidence from preclinical models.

Free Radical Biology and Medicine
2018-09 | Journal article
Source: Self-asserted source
MH Hoffmann

A model of chronic enthesitis and new bone formation characterized by multimodal imaging

Disese Models and Mechanisms
2018-08 | Journal article
Source: Self-asserted source
MH Hoffmann

Chemical Tools for Targeted Amplification of Reactive Oxygen Species in Neutrophils.

2018-08 | Journal article
Source: Self-asserted source
MH Hoffmann

Capability of Neutrophils to Form NETs Is Not Directly Influenced by a CMA-Targeting Peptide.

2017 | Journal article
Contributors: Maueröder C; Schall N; Meyer F; Mahajan A; Garnier B; Hahn J; Kienhöfer D; Hoffmann MH; Muller S
Source: Self-asserted source
MH Hoffmann via Europe PubMed Central

Altered cardiac gene expression of noradrenaline enzymes, transporter and

Autonomic neuroscience: Basic and Clinical
2017-12 | Journal article
Source: Self-asserted source
MH Hoffmann

Missing in action - the meaning of cell death in tissue damage and inflammation.

Immunological reviews
2017-11 | Journal article
Source: Self-asserted source
MH Hoffmann

Experimental lupus is aggravated in mouse strains with impaired induction of neutrophil extracellular traps.

2017-05 | Journal article
Contributors: Kienhöfer D; Hahn J; Stoof J; Csepregi JZ; Reinwald C; Urbonaviciute V; Johnsson C; Maueröder C; Podolska MJ; Biermann MH et al.
Source: Self-asserted source
MH Hoffmann via Europe PubMed Central

Neutrophil Extracellular Traps Drive Endothelial-to-Mesenchymal Transition.

2017-05 | Journal article
Contributors: Pieterse E; Rother N; Garsen M; Hofstra J; Satchell S; Hoffmann M; Loeven M; Knaapen H; van der Heijden O; Berden J et al.
Source: Self-asserted source
MH Hoffmann via Europe PubMed Central

Oxidative Burst-Dependent NETosis Is Implicated in the Resolution of Necrosis-Associated Sterile Inflammation.

2016 | Journal article
Contributors: Biermann MH; Podolska MJ; Knopf J; Reinwald C; Weidner D; Maueröder C; Hahn J; Kienhöfer D; Barras A; Boukherroub R et al.
Source: Self-asserted source
MH Hoffmann via Europe PubMed Central

Blood-borne phagocytes internalize urate microaggregates and prevent intravascular NETosis by urate crystals.

2016-12 | Journal article
Contributors: Pieterse E; Jeremic I; Czegley C; Weidner D; Biermann MH; Veissi S; Maueröder C; Schauer C; Bilyy R; Dumych T et al.
Source: Self-asserted source
MH Hoffmann via Europe PubMed Central

Reply to "Neutrophils are not required for resolution of acute gouty arthritis in mice".

2016-12 | Journal article
Contributors: Reinwald C; Schauer C; Csepregi JZ; Kienhöfer D; Weidner D; Malissen M; Mocsai A; Schett G; Herrmann M; Hoffmann M
Source: Self-asserted source
MH Hoffmann via Europe PubMed Central

Nanoparticles size-dependently initiate self-limiting NETosis-driven inflammation

PNAS
2016-10-04 | Journal article
Source: Self-asserted source
MH Hoffmann

Reactive oxygen homeostasis - the balance for preventing autoimmunity.

Lupus
2016-07 | Journal article
Source: Self-asserted source
MH Hoffmann

A novel mechanism for generating the interferon signature in lupus: opsonization of dead cells by complement and IgM

Arthritis & Rheumatology
2016-06-06 | Journal article
Source: Self-asserted source
MH Hoffmann

Animal models of rheumatoid arthritis (I): Pristane-induced arthritis in the rat.

PLOS One
2016-05-26 | Journal article
Source: Self-asserted source
MH Hoffmann

Bicarbonate-induced externalization of decondensed neutrophil chromatin occludes pancreatic ducts and drives pancreatitis

Nature Communications
2016-03-11 | Journal article
Source: Self-asserted source
MH Hoffmann

RNAi mediated silencing of hnRNP-A2/B1 inhibits inflammation and bone erosion in two experimental models of rheumatoid arthritis

Arthritis & Rheumatology
2015-08-26 | Journal article
Source: Self-asserted source
MH Hoffmann

Why does the gout attack stop? - A roadmap for the immune pathogenesis of gout

RMD Open
2015-08-15 | Journal article
Source: Self-asserted source
MH Hoffmann

How Neutrophil extracellular traps (NETs) orchestrate the local immune response in gout.

Journal of Molecular Medicine
2015-07 | Journal article
Source: Self-asserted source
MH Hoffmann

Vitamin D-dependent induction of cathelicidin in human macrophages results in cytotoxicity against high-grade B cell lymphoma.

Science Translational Medicine
2015-04-08 | Journal article
DOI:

10.1126/scitranslmed.aaa3230.

PMID:

25855493

Source: Self-asserted source
MH Hoffmann

Autoantibodies in Rheumatoid arthritis

2014 | Book chapter
Contributors: Markus Hoffmann
Source: Self-asserted source
MH Hoffmann

No evidence of pathogenic involvement of cathelicidins in patient cohorts and mouse models of lupus and arthritis

PLoS One
2014-12-23 | Journal article
PMID:

25535966

Source: Self-asserted source
MH Hoffmann

Monocytes and granulocytes orchestrate induction and resolution of inflammation in gout

Gout and Hyperuricemia
2014-09 | Journal article
DOI:

10.3966/GH1409010301

Source: Self-asserted source
MH Hoffmann

Reactive oxygen species deficiency induces autoimmunity with downstream interferon signature

Antioxidants & Redox signaling
2014-05 | Journal article
Contributors: MH Hoffmann
Source: Self-asserted source
MH Hoffmann

Aggregated neutrophil extracellular traps limit inflammation by degrading cytokines and chemokines

Nature Medicine
2014-04-28 | Journal article
Contributors: MH Hoffmann
Source: Self-asserted source
MH Hoffmann

Wolves in Sheep´s clothing: How chemically inert hydrocarbon oils induce autoimmunity

Immunome Research
2013-12-16 | Journal article
ISSN:

1745-7580 IMR

Source: Self-asserted source
MH Hoffmann

Cell death and cytokine production induced by autoimmunogenic hydrocarbon oils.

2012-12 | Journal article
PMID:

22917079

Contributors: Markus Hoffmann
Source: Self-asserted source
MH Hoffmann

The cathelicidins LL-37 and rCRAMP are associated with pathogenic events of arthritis in humans and rats.

Annals of the Rheumatic diseases
2012-11-21 | Journal article
PMID:

23172753

Contributors: Markus Hoffmann
Source: Self-asserted source
MH Hoffmann

Nucleic acid-stimulated antigen-presenting cells trigger T cells to induce disease in a rat transfer model of inflammatory arthritis.

Journal of Autoimmunity
2011-05 | Journal article
PMID:

21439786

Contributors: Markus Hoffmann
Source: Self-asserted source
MH Hoffmann

Nucleic acid-associated autoantigens: pathogenic involvement and therapeutic potential.

Journal of Autoimmunity
2010-05 | Journal article
PMID:

20031372

Contributors: Markus Hoffmann
Source: Self-asserted source
MH Hoffmann
Items per page:
Page 1 of 2

Peer review (2 reviews for 2 publications/grants)

Review activity for Nature communications (1)
Review activity for Nature immunology. (1)