Personal information

Activities

Employment (1)

University of Illinois System: Urbana-Champaign, Illinois, US

1987 to present | Professor (Chemistry)
Employment
Source: Self-asserted source
Zaida Luthey-Schulten

Education and qualifications (3)

Harvard University: Cambridge, MA, US

1975 | Ph.D. Applied Mathematis (Mathematics)
Education
Source: Self-asserted source
Zaida Luthey-Schulten

Harvard University: Cambridge, Massachusetts, US

1972 | M.S. Chemistry / Applied Mathematics (Chemistry)
Education
Source: Self-asserted source
Zaida Luthey-Schulten

University of Southern California: Los Angeles, California, US

1969 | B.S. Chemistry (minor in Mathematics) (Chemistry)
Education
Source: Self-asserted source
Zaida Luthey-Schulten

Professional activities (2)

University of Illinois at Urbana-Champaign: Urbana, IL, US

2019-04-10 | Murchison-Mallory Chair (Chemistry)
Distinction
Source: Self-asserted source
Zaida Luthey-Schulten

Biophysical Society: Rockville, Maryland, US

2019-02-10 | BPS Fellow
Distinction
Source: Self-asserted source
Zaida Luthey-Schulten

Funding (6)

Collaborative Research: PoLS Student Research Network

2015-10-01 to 2020-09-30 | Grant
National Science Foundation - Directorate for Mathematical & Physical Sciences (Arlington, US)
GRANT_NUMBER: 1505008
GRANT_NUMBER: 1505008
Source: Self-asserted source
Zaida Luthey-Schulten via DimensionsWizard

Quantitative Imaging and Modeling of Regulation by Bacterial Small RNA

2015-01-01 to 2019-11-30 | Grant
National Institute of General Medical Sciences (Bethesda, US)
GRANT_NUMBER: 1R01GM112659-01
GRANT_NUMBER: 1R01GM112659-01
Source: Self-asserted source
Zaida Luthey-Schulten via DimensionsWizard

Center for the Physics of Living Cells

2014-08 to 2020-08 | Grant
National Science Foundation (VA, VA, US)
Source: Self-asserted source
Zaida Luthey-Schulten

Evolution of Translation: From molecules to cells

2013-01-01 to 2016-12-31 | Grant
National Science Foundation - Directorate for Biological Sciences (Arlington, US)
GRANT_NUMBER: 1244570
GRANT_NUMBER: 1244570
Source: Self-asserted source
Zaida Luthey-Schulten via DimensionsWizard

NSF MCB 12-44570

Grant
National Science Foundation (Washington , DC, US)
Source: Self-asserted source
Zaida Luthey-Schulten

PHS Resource for macromolecular modeling

Grant
Public Health Service (Washington , DC, US)
Source: Self-asserted source
Zaida Luthey-Schulten

Works (50 of 112)

Items per page:
Page 1 of 3

Visualizing Cell Structures with Minecraft

The Biophysicist
2025-02-03 | Journal article
Contributors: Tianyu Wu; Zane R. Thornburg; Kevin Tan; Seth Kenkel; Stephen A. Boppart; Rohit Bhargava; Zaida Luthey-Schulten
Source: check_circle
Crossref

Modeling Diffusive Motion of Ferredoxin and Plastocyanin on the PSI Domain of Procholorococcus marinus MIT9313

The Journal of Physical Chemistry B
2025-01-09 | Journal article
Contributors: Aaron Chan; Emad Tajkhorshid; Zaida Luthey-Schulten; Melih Sener
Source: check_circle
Crossref

Replicating Chromosomes in Whole-Cell Models of Bacteria

2024 | Book chapter
Contributors: Benjamin R. Gilbert; Zaida Luthey-Schulten
Source: check_circle
Crossref

Toward the Complete Functional Characterization of a Minimal Bacterial Proteome

The Journal of Physical Chemistry B
2022-09-15 | Journal article
Contributors: David M. Bianchi; James F. Pelletier; Clyde A. Hutchison, III; John I. Glass; Zaida Luthey-Schulten
Source: check_circle
Crossref

Kinetic and structural mechanism for DNA unwinding by a non-hexameric helicase

Nature Communications
2021-12-01 | Journal article
Contributors: Sean P. Carney; Wen Ma; Kevin D. Whitley; Haifeng Jia; Timothy M. Lohman; Zaida Luthey-Schulten; Yann R. Chemla
Source: check_circle
Crossref

Integrating experiments, theory and simulations into whole-cell models

Nature Methods
2021-05-07 | Journal article
Contributors: Zaida Luthey-Schulten
Source: check_circle
Crossref

Effects of individual base-pairs on in vivo target search and destruction kinetics of bacterial small RNA

Nature Communications
2021-02-08 | Journal article
Contributors: Anustup Poddar; Muhammad S. Azam; Tunc Kayikcioglu; Maksym Bobrovskyy; Jichuan Zhang; Xiangqian Ma; Piyush Labhsetwar; Jingyi Fei; Digvijay Singh; Zaida Luthey-Schulten et al.
Source: check_circle
Crossref

Generalized correlation-based dynamical network analysis: a new high-performance approach for identifying allosteric communications in molecular dynamics trajectories

The Journal of Chemical Physics
2020-10-07 | Journal article
Contributors: Marcelo C. R. Melo; Rafael C. Bernardi; Cesar de la Fuente-Nunez; Zaida Luthey-Schulten
Source: check_circle
Crossref

Generalized correlation-based dynamical network analysis: a new high-performance approach for identifying allosteric communications in molecular dynamics trajectories

2020-06-20 | Preprint
Contributors: Marcelo C. R. Melo; Rafael C. Bernardi; Cesar de la Fuente-Nunez; Zaida Luthey-Schulten
Source: check_circle
Crossref

Bacteria on steroids: the enzymatic mechanism of an NADH-dependent dehydrogenase that regulates the conversion of cortisol to androgen in the gut microbiome

2020-06-13 | Preprint
Contributors: Rafael C. Bernardi; Heidi L. Doden; Marcelo C.R. Melo; Saravanan Devendran; Rebecca M. Pollet; Sean M. Mythen; Shiva Bhowmik; Scott A. Lesley; Isaac Cann; Zaida Luthey-Schulten et al.
Source: check_circle
Crossref

An in-silico human cell model reveals the influence of spatial organization on RNA splicing

PLOS Computational Biology
2020-03-25 | Journal article
Contributors: Zhaleh Ghaemi; Attila Csikász-Nagy; Joseph R. Peterson; Martin Gruebele; Zaida Luthey-Schulten
Source: check_circle
Crossref

Complete structure of the chemosensory array core signalling unit in an E. coli minicell strain

Nature Communications
2020-02-06 | Journal article
Contributors: Alister Burt; C. Keith Cassidy; Peter Ames; Maria Bacia-Verloop; Megghane Baulard; Karine Huard; Zaida Luthey-Schulten; Ambroise Desfosses; Phillip J. Stansfeld; William Margolin et al.
Source: check_circle
Crossref

Structure and dynamics of the E. coli chemotaxis core signaling complex by cryo-electron tomography and molecular simulations

Communications Biology
2020-01-10 | Journal article
Contributors: C. Keith Cassidy; Benjamin A. Himes; Dapeng Sun; Jun Ma; Gongpu Zhao; John S. Parkinson; Phillip J. Stansfeld; Zaida Luthey-Schulten; Peijun Zhang
Source: check_circle
Crossref

Simulating biological processes: stochastic physics from whole cells to colonies

Reports on Progress in Physics
2018-05-01 | Journal article
Contributors: Tyler M Earnest; John A Cole; Zaida Luthey-Schulten
Source: check_circle
Crossref

Free-energy simulations reveal molecular mechanism for functional switch of a DNA helicase

eLife
2018-04-17 | Journal article
Contributors: Wen Ma; Kevin D Whitley; Yann R Chemla; Zaida Luthey-Schulten; Klaus Schulten
Source: check_circle
Crossref

Genome-Scale Metabolic Modeling of Archaea Lends Insight into Diversity of Metabolic Function

Archaea
2017 | Journal article
Contributors: ShengShee Thor; Joseph R. Peterson; Zaida Luthey-Schulten
Source: check_circle
Crossref

Population FBA predicts metabolic phenotypes in yeast

PLOS Computational Biology
2017-09-08 | Journal article
Contributors: Piyush Labhsetwar; Jason A Papin; Marcelo C. R. Melo; John A. Cole; Zaida Luthey-Schulten
Source: check_circle
Crossref

Computational Modeling of Fluctuations in Energy and Metabolic Pathways of Methanogenic Archaea

2017-01-04 | Report
Contributors: Zaida Luthey-Schulten
Source: check_circle
Crossref

Analysis of the Resistance Mechanism of a Benzoxaborole Inhibitor Reveals Insight into the Leucyl-tRNA Synthetase Editing Mechanism

ACS Chemical Biology
2015 | Journal article
EID:

2-s2.0-84944742995

Contributors: Zhao, H.; Palencia, A.; Seiradake, E.; Ghaemi, Z.; Cusack, S.; Luthey-Schulten, Z.; Martinis, S.
Source: Self-asserted source
Zaida Luthey-Schulten via Scopus - Elsevier

Native conformational dynamics of the spliceosomal U1A protein

Journal of Physical Chemistry B
2015 | Journal article
EID:

2-s2.0-84929340363

Contributors: Guzman, I.; Ghaemi, Z.; Baranger, A.; Luthey-Schulten, Z.; Gruebele, M.
Source: Self-asserted source
Zaida Luthey-Schulten via Scopus - Elsevier

Spatially-resolved metabolic cooperativity within dense bacterial colonies

BMC Systems Biology
2015 | Journal article
EID:

2-s2.0-84925776751

Contributors: Cole, J.A.; Kohler, L.; Hedhli, J.; Luthey-Schulten, Z.
Source: Self-asserted source
Zaida Luthey-Schulten via Scopus - Elsevier

Toward a Whole-Cell Model of Ribosome Biogenesis: Kinetic Modeling of SSU Assembly

Biophysical Journal
2015 | Journal article
EID:

2-s2.0-84941804712

Contributors: Earnest, T.M.; Lai, J.; Chen, K.; Hallock, M.J.; Williamson, J.R.; Luthey-Schulten, Z.
Source: Self-asserted source
Zaida Luthey-Schulten via Scopus - Elsevier

Erratum: DNA looping increases the range of bistability in a stochastic model of the lac genetic switch (Physical Biology (2013) 10 (026002))

Physical Biology
2014 | Journal article
EID:

2-s2.0-84897529916

Contributors: Earnest, T.M.; Roberts, E.; Assaf, M.; Dahmen, K.; Luthey-Schulten, Z.
Source: Self-asserted source
Zaida Luthey-Schulten via Scopus - Elsevier

Erratum: Heterogeneity in protein expression induces metabolic variability in a modeled Escherichia coli population (Proceedings of the National Academy of Sciences of the United States of America (2013) 110(14006-14011) DOI:10.1073/pnas.1222569110)

Proceedings of the National Academy of Sciences of the United States of America
2014 | Journal article
EID:

2-s2.0-84892587064

Contributors: Labhsetwar, P.; Cole, J.A.; Roberts, E.; Price, N.D.; Luthey-Schulten, Z.A.
Source: Self-asserted source
Zaida Luthey-Schulten via Scopus - Elsevier

Protein-guided RNA dynamics during early ribosome assembly

Nature
2014 | Journal article
EID:

2-s2.0-84894235917

Contributors: Kim, H.; Abeysirigunawarden, S.C.; Chen, K.; Mayerle, M.; Ragunathan, K.; Luthey-Schulten, Z.; Ha, T.; Woodson, S.A.
Source: Self-asserted source
Zaida Luthey-Schulten via Scopus - Elsevier

Simulation of reaction diffusion processes over biologically relevant size and time scales using multi-GPU workstations

Parallel Computing
2014 | Journal article
EID:

2-s2.0-84899427023

Contributors: Hallock, M.J.; Stone, J.E.; Roberts, E.; Fry, C.; Luthey-Schulten, Z.
Source: Self-asserted source
Zaida Luthey-Schulten via Scopus - Elsevier

Towards a computational model of a methane producing archaeum

Archaea
2014 | Journal article
EID:

2-s2.0-84896458791

Contributors: Peterson, J.R.; Labhsetwar, P.; Ellermeier, J.R.; Kohler, P.R.A.; Jain, A.; Ha, T.; Metcalf, W.W.; Luthey-Schulten, Z.
Source: Self-asserted source
Zaida Luthey-Schulten via Scopus - Elsevier

Whole cell modeling: From single cells to colonies

Israel Journal of Chemistry
2014 | Journal article
EID:

2-s2.0-84905315830

Contributors: Cole, J.A.; Luthey-Schulten, Z.
Source: Self-asserted source
Zaida Luthey-Schulten via Scopus - Elsevier

Capture and quality control mechanisms for adenosine-5′-triphosphate binding

Journal of the American Chemical Society
2013 | Journal article
EID:

2-s2.0-84876721020

Contributors: Li, L.; Martinis, S.A.; Luthey-Schulten, Z.
Source: Self-asserted source
Zaida Luthey-Schulten via Scopus - Elsevier

DNA looping increases the range of bistability in a stochastic model of the lac genetic switch

Physical Biology
2013 | Journal article
EID:

2-s2.0-84876242563

Contributors: Earnest, T.M.; Roberts, E.; Assaf, M.; Dahmen, K.; Luthey-Schulten, Z.
Source: Self-asserted source
Zaida Luthey-Schulten via Scopus - Elsevier

Extrinsic noise driven phenotype switching in a self-regulating gene

Physical review letters
2013 | Journal article
EID:

2-s2.0-84925023727

Contributors: Assaf, M.; Roberts, E.; Luthey-Schulten, Z.; Goldenfeld, N.
Source: Self-asserted source
Zaida Luthey-Schulten via Scopus - Elsevier

Extrinsic noise driven phenotype switching in a self-regulating gene

Physical Review Letters
2013 | Journal article
EID:

2-s2.0-84881491748

Contributors: Assaf, M.; Roberts, E.; Luthey-Schulten, Z.; Goldenfeld, N.
Source: Self-asserted source
Zaida Luthey-Schulten via Scopus - Elsevier

Heterogeneity in protein expression induces metabolic variability in a modeled Escherichia coli population

Proceedings of the National Academy of Sciences of the United States of America
2013 | Journal article
EID:

2-s2.0-84882748254

Contributors: Labhsetwar, P.; Cole, J.A.; Roberts, E.; Price, N.D.; Luthey-Schulten, Z.A.
Source: Self-asserted source
Zaida Luthey-Schulten via Scopus - Elsevier

Lattice microbes: High-performance stochastic simulation method for the reaction-diffusion master equation

Journal of Computational Chemistry
2013 | Journal article
EID:

2-s2.0-84872288144

Contributors: Roberts, E.; Stone, J.E.; Luthey-Schulten, Z.
Source: Self-asserted source
Zaida Luthey-Schulten via Scopus - Elsevier

Leucyl-tRNA synthetase editing domain functions as a molecular rheostat to control codon ambiguity in mycoplasma pathogens

Proceedings of the National Academy of Sciences of the United States of America
2013 | Journal article
EID:

2-s2.0-84874633001

Contributors: Li, L.; Palencia, A.; Lukk, T.; Li, Z.; Luthey-Schulten, Z.A.; Cusack, S.; Martinis, S.A.; Boniecki, M.T.
Source: Self-asserted source
Zaida Luthey-Schulten via Scopus - Elsevier

Stochastic Simulations of Cellular Processes: From Single Cells to Colonies

Computational Systems Biology: From Molecular Mechanisms to Disease: Second Edition
2013 | Book
EID:

2-s2.0-84902394579

Contributors: Cole, J.; Hallock, M.J.; Labhsetwar, P.; Peterson, J.R.; Stone, J.E.; Luthey-Schulten, Z.
Source: Self-asserted source
Zaida Luthey-Schulten via Scopus - Elsevier

Structural intermediates and folding events in the early assembly of the ribosomal small subunit

Journal of Physical Chemistry B
2013 | Journal article
EID:

2-s2.0-84886646813

Contributors: Lai, J.; Chen, K.; Luthey-Schulten, Z.
Source: Self-asserted source
Zaida Luthey-Schulten via Scopus - Elsevier

Assembly of the five-way junction in the ribosomal small subunit using hybrid MD-Gō simulations

Journal of Physical Chemistry B
2012 | Journal article
EID:

2-s2.0-84862271578

Contributors: Chen, K.; Eargle, J.; Lai, J.; Kim, H.; Abeysirigunawardena, S.; Mayerle, M.; Woodson, S.; Ha, T.; Luthey-Schulten, Z.
Source: Self-asserted source
Zaida Luthey-Schulten via Scopus - Elsevier

Exploring residue component contributions to dynamical network models of allostery

Journal of Chemical Theory and Computation
2012 | Journal article
EID:

2-s2.0-84865063074

Contributors: Vanwart, A.T.; Eargle, J.; Luthey-Schulten, Z.; Amaro, R.E.
Source: Self-asserted source
Zaida Luthey-Schulten via Scopus - Elsevier

Network view: 3D display and analysis of protein ·rNA interaction networks

Bioinformatics
2012 | Journal article
EID:

2-s2.0-84869418186

Contributors: Eargle, J.; Luthey-Schulten, Z.
Source: Self-asserted source
Zaida Luthey-Schulten via Scopus - Elsevier

Determining the stability of genetic switches: Explicitly accounting for mRNA noise

Physical Review Letters
2011 | Journal article
EID:

2-s2.0-79960640740

Contributors: Assaf, M.; Roberts, E.; Luthey-Schulten, Z.
Source: Self-asserted source
Zaida Luthey-Schulten via Scopus - Elsevier

Naturally occurring aminoacyl-tRNA synthetases editing-domain mutations that cause mistranslation in Mycoplasma parasites

Proceedings of the National Academy of Sciences of the United States of America
2011 | Journal article
EID:

2-s2.0-79959348607

Contributors: Li, L.; Boniecki, M.T.; Jaffe, J.D.; Imai, B.S.; Yau, P.M.; Luthey-Schulten, Z.A.; Martinis, S.A.
Source: Self-asserted source
Zaida Luthey-Schulten via Scopus - Elsevier

Noise contributions in an inducible genetic switch: A whole-cell simulation study

PLoS Computational Biology
2011 | Journal article
EID:

2-s2.0-79953666361

Contributors: Roberts, E.; Magis, A.; Ortiz, J.O.; Baumeister, W.; Luthey-Schulten, Z.
Source: Self-asserted source
Zaida Luthey-Schulten via Scopus - Elsevier

Exit strategies for charged tRNA from GluRS

Journal of Molecular Biology
2010 | Journal article
EID:

2-s2.0-77950518101

Contributors: Black Pyrkosz, A.; Eargle, J.; Sethi, A.; Luthey-Schulten, Z.
Source: Self-asserted source
Zaida Luthey-Schulten via Scopus - Elsevier

Experimental and computational determination of tRNA dynamics

FEBS Letters
2010 | Journal article
EID:

2-s2.0-71549156528

Contributors: Alexander, R.W.; Eargle, J.; Luthey-Schulten, Z.
Source: Self-asserted source
Zaida Luthey-Schulten via Scopus - Elsevier

Functional role of ribosomal signatures

Biophysical Journal
2010 | Journal article
EID:

2-s2.0-78650211733

Contributors: Chen, K.; Eargle, J.; Sarkar, K.; Gruebele, M.; Luthey-Schulten, Z.
Source: Self-asserted source
Zaida Luthey-Schulten via Scopus - Elsevier

Influence of montmorillonite on nucleotide oligomerization reactions: A molecular dynamics study

Origins of Life and Evolution of Biospheres
2010 | Journal article
EID:

2-s2.0-77951767420

Contributors: Mathew, D.C.; Luthey-Schulten, Z.
Source: Self-asserted source
Zaida Luthey-Schulten via Scopus - Elsevier

The Role of L1 Stalk-tRNA Interaction in the Ribosome Elongation Cycle

Journal of Molecular Biology
2010 | Journal article
EID:

2-s2.0-77956935085

Contributors: Trabuco, L.G.; Schreiner, E.; Eargle, J.; Cornish, P.; Ha, T.; Luthey-Schulten, Z.; Schulten, K.
Source: Self-asserted source
Zaida Luthey-Schulten via Scopus - Elsevier

Dynamical networks in tRNA: Protein complexes

Proceedings of the National Academy of Sciences of the United States of America
2009 | Journal article
EID:

2-s2.0-66149086947

Contributors: Sethi, A.; Eargle, J.; Black, A.A.; Luthey-Schulten, Z.
Source: Self-asserted source
Zaida Luthey-Schulten via Scopus - Elsevier

Extreme genetic code optimality from a molecular dynamics calculation of amino acid polar requirement

Physical Review E - Statistical, Nonlinear, and Soft Matter Physics
2009 | Journal article
EID:

2-s2.0-67649992002

Contributors: Butler, T.; Goldenfeld, N.; Mathew, D.; Luthey-Schulten, Z.
Source: Self-asserted source
Zaida Luthey-Schulten via Scopus - Elsevier
Items per page:
Page 1 of 3

Peer review (5 reviews for 5 publications/grants)

Review activity for Journal of chemical theory and computation : (1)
Review activity for Journal of proteome research. (1)
Review activity for Journal of the American Chemical Society. (1)
Review activity for Nature communications (1)
Review activity for Nature methods. (1)