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Holistic Approach to Process Design and Scale-Up for Itaconic Acid Production from Crude Substrates

Bioengineering
2023-06 | Journal article | Author
Contributors: Katharina Maria Saur; Robert Kiefel; Paul-Joachim Niehoff; Jordy Hofstede; Philipp Ernst; Johannes Markus Josef Brockkötter; Jochem Gätgens; Joern Viell; Stephan Noack; Nick Wierckx et al.
Source: check_circle
Multidisciplinary Digital Publishing Institute

Communities of Niche-Optimized Strains: Small-Genome Organism Consortia in Bioproduction

Trends in Biotechnology
2018 | Journal article
EID:

2-s2.0-85051362162

Contributors: Noack, S.; Baumgart, M.
Source: Self-asserted source
Stephan Noack via Scopus - Elsevier

Corynebacterium glutamicum Chassis C1∗: Building and Testing a Novel Platform Host for Synthetic Biology and Industrial Biotechnology

ACS Synthetic Biology
2018 | Journal article
EID:

2-s2.0-85040865494

Contributors: Baumgart, M.; Unthan, S.; Kloß, R.; Radek, A.; Polen, T.; Tenhaef, N.; Müller, M.F.; Küberl, A.; Siebert, D.; Brühl, N. et al.
Source: Self-asserted source
Stephan Noack via Scopus - Elsevier

Microbioreactor Systems for Accelerated Bioprocess Development

Biotechnology Journal
2018 | Journal article
EID:

2-s2.0-85041071955

Contributors: Hemmerich, J.; Noack, S.; Wiechert, W.; Oldiges, M.
Source: Self-asserted source
Stephan Noack via Scopus - Elsevier

Production of D-xylonic acid using a non-recombinant Corynebacterium glutamicum strain

Bioresource Technology
2018 | Journal article
EID:

2-s2.0-85051013816

Contributors: Tenhaef, N.; Brüsseler, C.; Radek, A.; Hilmes, R.; Unrean, P.; Marienhagen, J.; Noack, S.
Source: Self-asserted source
Stephan Noack via Scopus - Elsevier

Quantitative measurements in single-cell analysis: towards scalability in microbial bioprocess development

Current Opinion in Biotechnology
2018 | Journal article
EID:

2-s2.0-85044460133

Contributors: Demling, P.; Westerwalbesloh, C.; Noack, S.; Wiechert, W.; Kohlheyer, D.
Source: Self-asserted source
Stephan Noack via Scopus - Elsevier

The myo-inositol/proton symporter IolT1 contributes to D-xylose uptake in Corynebacterium glutamicum

Bioresource Technology
2018 | Journal article
EID:

2-s2.0-85033385407

Contributors: Brüsseler, C.; Radek, A.; Tenhaef, N.; Krumbach, K.; Noack, S.; Marienhagen, J.
Source: Self-asserted source
Stephan Noack via Scopus - Elsevier

Accelerated bioprocess development in automated micro-scale,Beschleunigte Bioprozessentwicklung im automatisierten Mikromaßstab

BioSpektrum
2017 | Journal article
EID:

2-s2.0-85029054109

Contributors: Morschett, H.; Noack, S.; Oldiges, M.
Source: Self-asserted source
Stephan Noack via Scopus - Elsevier

Comprehensive and accurate tracking of carbon origin of LC-tandem mass spectrometry collisional fragments for<sup>13</sup>C-MFA

Analytical and Bioanalytical Chemistry
2017 | Journal article
EID:

2-s2.0-85010739195

Contributors: Kappelmann, J.; Klein, B.; Geilenkirchen, P.; Noack, S.
Source: Self-asserted source
Stephan Noack via Scopus - Elsevier

Disruption of mycobacterial aftB results in complete loss of terminal β(1 → 2) arabinofuranose residues of Lipoarabinomannan

ACS Chemical Biology
2017 | Journal article
EID:

2-s2.0-85021859324

Contributors: Jankute, M.; Alderwick, L.J.; Noack, S.; Veerapen, N.; Nigou, J.; Besra, G.S.
Source: Self-asserted source
Stephan Noack via Scopus - Elsevier

Dynamic flux balance analysis with nonlinear objective function

Journal of Mathematical Biology
2017 | Journal article
EID:

2-s2.0-85017472725

Contributors: Zhao, X.; Noack, S.; Wiechert, W.; Lieres, E.
Source: Self-asserted source
Stephan Noack via Scopus - Elsevier

Miniaturized and automated adaptive laboratory evolution: Evolving Corynebacterium glutamicum towards an improved D-xylose utilization

Bioresource Technology
2017 | Journal article
EID:

2-s2.0-85019835431

Contributors: Radek, A.; Tenhaef, N.; Müller, M.F.; Brüsseler, C.; Wiechert, W.; Marienhagen, J.; Polen, T.; Noack, S.
Source: Self-asserted source
Stephan Noack via Scopus - Elsevier

Mutations in MurE, the essential UDP-N-acetylmuramoylalanyl-d-glutamate 2,6-diaminopimelate ligase of Corynebacterium glutamicum: effect on l-lysine formation and analysis of systemic consequences

Biotechnology Letters
2017 | Journal article
EID:

2-s2.0-84992385109

Contributors: Hochheim, J.; Kranz, A.; Krumbach, K.; Sokolowsky, S.; Eggeling, L.; Noack, S.; Bocola, M.; Bott, M.; Marienhagen, J.
Source: Self-asserted source
Stephan Noack via Scopus - Elsevier

Real-time monitoring of fungal growth and morphogenesis at single-cell resolution

Engineering in Life Sciences
2017 | Journal article
EID:

2-s2.0-84989232420

Contributors: Gr�nberger, A.; Sch�ler, K.; Probst, C.; Kornfeld, G.; Hardiman, T.; Wiechert, W.; Kohlheyer, D.; Noack, S.
Source: Self-asserted source
Stephan Noack via Scopus - Elsevier

The linkage between nutrient supply, intracellular enzyme abundances and bacterial growth: New evidences from the central carbon metabolism of Corynebacterium glutamicum

Journal of Biotechnology
2017 | Journal article
EID:

2-s2.0-85021879314

Contributors: Noack, S.; Voges, R.; Gätgens, J.; Wiechert, W.
Source: Self-asserted source
Stephan Noack via Scopus - Elsevier

A FRET-based lysine sensor toolbox with different affinity and sensitivity

2016 | Conference poster
SOURCE-WORK-ID: FZJ-2016-02824
Contributors: Steffen, Victoria; Otten, Julia; Radek, Andreas; Engelmann, Susann; Wiechert, Wolfgang; Noack, Stephan; Pohl, Martina
Source: check_circle
Forschungszentrum Jülich

A toolbox of genetically encoded FRET-based biosensors for rapid L-lysine analysis

Sensors (Switzerland)
2016 | Journal article
EID:

2-s2.0-84989361136

Contributors: Steffen, V.; Otten, J.; Engelmann, S.; Radek, A.; Limberg, M.; Koenig, B.W.; Noack, S.; Wiechert, W.; Pohl, M.
Source: Self-asserted source
Stephan Noack via Scopus - Elsevier

BOOST FUND BEProMod - Incremental multi-scale and multi-disciplinary modeling of processes in bioeconomy

2016 | Conference poster
SOURCE-WORK-ID: FZJ-2016-01801
Contributors: Mitsos, A.; Hannemann-Tamas, R.; Ploch, T.; Wiechert, Wolfgang; von Lieres, Eric; Noack, Stephan; Zhao, Xiao; Naumann, U.; Lotz, J.; Hueser, J.
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Forschungszentrum Jülich

Cutting the gordian knot: identifiability of anaplerotic reactions in Corynebacterium glutamicum by means of $^{13}$C-metabolic flux analysis

Biotechnology & bioengineering
2016 | Journal article
SOURCE-WORK-ID: FZJ-2015-07590
Part of ISSN: 0006-3592
Contributors: Kappelmann, Jannick; Wiechert, Wolfgang; Noack, Stephan
Source: check_circle
Forschungszentrum Jülich

Engineering of Corynebacterium glutamicum as platform for flexible and carbon efficient utilization of D-Xylose containing feedstocks

2016 | Lecture
SOURCE-WORK-ID: FZJ-2015-07330
Contributors: Noack, Stephan; Radek, Andreas; Krumbach, Karin; Marienhagen, Jan
Source: check_circle
Forschungszentrum Jülich

Enhanced protein and biochemical production using CRISPRi-based growth switches

Metabolic Engineering
2016 | Journal article
EID:

2-s2.0-84988911466

Contributors: Li, S.; Jendresen, C.B.; Grünberger, A.; Ronda, C.; Jensen, S.I.; Noack, S.; Nielsen, A.T.
Source: Self-asserted source
Stephan Noack via Scopus - Elsevier

Formation of xylitol and xylitol-5-phosphate and its impact on growth of D-xylose-utilizing Corynebacterium glutamicum strains

Journal of Biotechnology
2016 | Journal article
EID:

2-s2.0-84975830542

Contributors: Radek, A.; Müller, M.-F.; Gätgens, J.; Eggeling, L.; Krumbach, K.; Marienhagen, J.; Noack, S.
Source: Self-asserted source
Stephan Noack via Scopus - Elsevier

FRET-Based Biosensors for Online Measurement of Lysine Production

Chemie-Ingenieur-Technik
2016 | Journal article
EID:

2-s2.0-85008239389

Contributors: Steffen, V.; Otten, J.; Radek, A.; Wiechert, W.; Noack, S.; Pohl, M.
Source: Self-asserted source
Stephan Noack via Scopus - Elsevier

Identification of the phd gene cluster responsible for phenylpropanoid utilization in Corynebacterium glutamicum

Applied microbiology and biotechnology
2016 | Journal article
SOURCE-WORK-ID: FZJ-2015-07041
Part of ISSN: 1432-0614
Contributors: Kallscheuer, Nicolai; Vogt, Michael; Kappelmann, Jannick; Krumbach, Karin; Noack, Stephan; Bott, Michael; Marienhagen, Jan
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Forschungszentrum Jülich

Progress and current results

2016 | Lecture
SOURCE-WORK-ID: FZJ-2016-01658
Contributors: Zhao, Xiao; Noack, Stephan; von Lieres, Eric; Wiechert, Wolfgang
Source: check_circle
Forschungszentrum Jülich

Quantitative Proteomics

2016 | Lecture
SOURCE-WORK-ID: FZJ-2016-02727
Contributors: Noack, Stephan
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Forschungszentrum Jülich

Absolute quantification of Corynebacterium glutamicum and anaplerotic enzymes by QconCAT

Journal of proteomics
2015 | Journal article
SOURCE-WORK-ID: FZJ-2014-06577
Part of ISSN: 1874-3919
WOSUID:

000347582200026

Contributors: Voges, Raphael; Corsten, Stephanie; Wiechert, Wolfgang; Noack, Stephan
Source: check_circle
Forschungszentrum Jülich

Beyond growth rate 0.6: Summary and ongoing work

2015 | Lecture
SOURCE-WORK-ID: FZJ-2015-02739
Contributors: Noack, Stephan
Source: check_circle
Forschungszentrum Jülich

Bioprocess Automation for Fast Microbial Strain Selection and Detailed Quantitative Phenotyping

2015 | Conference poster
SOURCE-WORK-ID: FZJ-2015-03189
Contributors: Radek, Andreas; Unthan, Simon; Oldiges, Marco; Noack, Stephan
Source: check_circle
Forschungszentrum Jülich

Bioprocess automation on a Mini Pilot Plant enables fast quantitative microbial phenotyping

Microbial cell factories
2015 | Journal article
SOURCE-WORK-ID: FZJ-2015-02095
Part of ISSN: 1475-2859
HANDLE: 2128/8456
WOSUID:

000351272200001

Contributors: Unthan, Simon; Radek, Andreas; Wiechert, Wolfgang; Oldiges, Marco; Noack, Stephan
Source: check_circle
Forschungszentrum Jülich

Chassis organism from Corynebacterium glutamicum - a top-down approach to identify and delete irrelevant gene clusters

Biotechnology journal
2015 | Journal article
SOURCE-WORK-ID: FZJ-2015-01450
Part of ISSN: 1860-6768
HANDLE: 2128/8400
WOSUID:

000350104700010

Contributors: Unthan, Simon; Baumgart, Meike; Radek, Andreas; Herbst, Marius; Siebert, Daniel; Brühl, Natalie; Bartsch, Anna; Bott, Michael; Wiechert, Wolfgang; Marin, Kay et al.
Source: check_circle
Forschungszentrum Jülich

Chassis organism from Corynebacterium glutamicum - Genome reduction as a tool towards improved strains for synthetic biology and industrial biotechnology

2015 | Lecture
SOURCE-WORK-ID: FZJ-2015-07405
Contributors: Baumgart, Meike; Unthan, Simon; Radek, Andreas; Herbst, Marius; Siebert, Daniel; Brühl, Natalie; Bartsch, Anna; Bott, Michael; Wiechert, Wolfgang; Marin, Kay et al.
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Forschungszentrum Jülich

Combinatorial optimization of synthetic operons for the microbial production of p-coumaryl alcohol with Escherichia coli

Microbial cell factories
2015 | Journal article
SOURCE-WORK-ID: FZJ-2015-03931
Part of ISSN: 1475-2859
HANDLE: 2128/8887
WOSUID:

000355907600001

Contributors: van Summeren, Philana; Voges, Raphael; Dennig, Alexander; Sokolowsky, Sascha; Noack, Stephan; Schwaneberg, Ulrich; Marienhagen, Jan
Source: check_circle
Forschungszentrum Jülich

Combinatorial optimization of synthetic operons for the microbial production of p-coumaryl alcohol with Escherichia coli

2015 | Conference poster
SOURCE-WORK-ID: FZJ-2015-07346
Contributors: Aschenbrenner, Jennifer; van Summeren, Philana; Voges, Raphael; Dennig, Alexander; Sokolowsky, Sascha; Noack, Stephan; Schwaneberg, Ulrich; Marienhagen, Jan
Source: check_circle
Forschungszentrum Jülich

Combinatorial optimization of synthetic operons for the microbial production of p-coumaryl alcohol with Escherichia coli

2015 | Conference poster
SOURCE-WORK-ID: FZJ-2015-07307
Contributors: van Summeren, Philana; Voges, Raphael; Sokolowsky, Sascha; Noack, Stephan; Marienhagen, Jan
Source: check_circle
Forschungszentrum Jülich

Combinatorial optimization of synthetic operons for the microbial production of p-coumaryl alcohol with Escherichia coli

2015 | Conference poster
SOURCE-WORK-ID: FZJ-2015-07305
Contributors: van Summeren, Philana; Voges, Raphael; Sokolowsky, Sascha; Noack, Stephan; Marienhagen, Jan
Source: check_circle
Forschungszentrum Jülich

Coupled simulation of bioreactor and metabolic network dynamics by ordinary differential equations with embedded optimization

2015 | Conference poster
SOURCE-WORK-ID: FZJ-2016-00334
Contributors: Zhao, Xiao; Noack, Stephan; von Lieres, Eric; Wiechert, Wolfgang
Source: check_circle
Forschungszentrum Jülich

Engineering of Corynebacterium glutamicum as platform for flexible and efficient utilization of D-xylose containing feedstocks

2015 | Conference poster
SOURCE-WORK-ID: FZJ-2015-06490
Contributors: Radek, Andreas; Krumbach, Karin; Marienhagen, Jan; Noack, Stephan
Source: check_circle
Forschungszentrum Jülich

Enzymprozesstechnik

2015 | Lecture
SOURCE-WORK-ID: FZJ-2015-06155
Contributors: Noack, Stephan
Source: check_circle
Forschungszentrum Jülich

Genome Reduction and Quantitative Phenotyping: Important Drivers for Systems Biology and Metabolic Engineering of Platform Organisms

2015 | Conference poster
SOURCE-WORK-ID: FZJ-2015-03251
Contributors: Noack, Stephan; Unthan, Simon; Voges, Raphael; Wiechert, Wolfgang
Source: check_circle
Forschungszentrum Jülich

Genome Reduction and Quantitative Phenotyping: Important Drivers for Systems Biology and Metabolic Engineering of Platform Organisms

2015 | Conference poster
SOURCE-WORK-ID: FZJ-2015-04724
Contributors: Unthan, Simon; Voges, Raphael; Wiechert, Wolfgang; Noack, Stephan
Source: check_circle
Forschungszentrum Jülich

Metabolic Engineering of Corynebacterium glutamicum for Methanol metabolism

Applied and environmental microbiology
2015 | Journal article
SOURCE-WORK-ID: FZJ-2015-02208
Part of ISSN: 1098-5336
WOSUID:

000350554800038

Contributors: Witthoff, Sabrina; Schmitz, Katja; Niedenführ, Sebastian; Nöh, Katharina; Noack, Stephan; Bott, Michael; Marienhagen, Jan
Source: check_circle
Forschungszentrum Jülich

Omics for all Seasons: Toolboxes for Bioprocess Development

2015 | Lecture
SOURCE-WORK-ID: FZJ-2015-03269
Contributors: Wiechert, Wolfgang; Noack, Stephan
Source: check_circle
Forschungszentrum Jülich

Quantitative Biotechnologie am Forschungszentrum Jülich: One-Stop-Shopping für die Stamm- und Prozessentwicklung

Systembiologie.de
2015 | Journal article
SOURCE-WORK-ID: FZJ-2015-04703
Part of ISSN: 2191-2505
Contributors: Noack, Stephan; Wiechert, Wolfgang
Source: check_circle
Forschungszentrum Jülich

Quantitative Biotechnology at Forschungszentrum Jülich: One-stop Shopping for strain and process development

Systembiologie.de
2015 | Journal article
SOURCE-WORK-ID: FZJ-2015-04702
Part of ISSN: 2191-2505
Contributors: Noack, Stephan; Wiechert, Wolfgang
Source: check_circle
Forschungszentrum Jülich

Quantitative Phenotyping of Mutant Strains under Process relevant Conditions: Experiences from a Genome Reduction Project

2015 | Lecture
SOURCE-WORK-ID: FZJ-2015-05705
Contributors: Wiechert, Wolfgang; Oldiges, Marco; Noack, Stephan
Source: check_circle
Forschungszentrum Jülich

Single-cell microfluidics meets applied biotechnology: From expectation to application

2015 | Lecture
SOURCE-WORK-ID: FZJ-2015-03250
Contributors: Grünberger, Alexander; Probst, Christopher; Frunzke, Julia; Noack, Stephan; Wiechert, Wolfgang; Kohlheyer, Dietrich
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Forschungszentrum Jülich

Single-cell microfluidics meets applied biotechnology: From expectation to application

2015 | Conference poster
SOURCE-WORK-ID: FZJ-2015-03249
Contributors: Grünberger, Alexander; Probst, Christopher; Frunzke, Julia; Noack, Stephan; Wiechert, Wolfgang; Kohlheyer, Dietrich
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Forschungszentrum Jülich

Single-cell microfluidics meets applied biotechnology: From expectation to application

2015 | Conference poster
SOURCE-WORK-ID: FZJ-2015-05410
Contributors: Grünberger, Alexander; Probst, Christopher; Frunzke, Julia; Noack, Stephan; Wiechert, Wolfgang; Kohlheyer, Dietrich
Source: check_circle
Forschungszentrum Jülich

Systems-Biotechnology at Forschungszentrum Jülich

2015 | Lecture
SOURCE-WORK-ID: FZJ-2015-05701
Contributors: Wiechert, Wolfgang; Oldiges, Marco; von Lieres, Eric; Noack, Stephan; Nöh, Katharina; Pohl, Martina; Rother, Dörte; Kohlheyer, Dietrich
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Forschungszentrum Jülich
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Peer review (8 reviews for 6 publications/grants)

Review activity for ACS sustainable chemistry & engineering. (2)
Review activity for ACS synthetic biology. (1)
Review activity for Analytical chemistry. (1)
Review activity for Bioresource technology. (2)
Review activity for Microbial cell factories (1)
Review activity for Nature communications (1)