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Cannabinoids; Neural Stem Cells; Neurodevelopment; Neurodegeneration; Neurogenesis
Portugal

Biography

PhD in Biomedical Sciences - Neuroscience, specializing in non-psychoactive cannabinoids' impact on neural stem cell differentiation for neurodegenerative diseases. MSc in Neuroscience from King's College London with expertise in modelling Parkinson's disease. Research interests include cannabinoids, neural stem cells, neurodevelopment, neurodegeneration, neurogenesis, and pharmacology. Committed to advancing neuroscience and making significant contributions to the field.

Activities

Employment (6)

Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes: Lisboa, PT

2018-04 to 2023-12 | PhD student at ASebastião Lab (Instituto de Farmacologia e Neurociências)
Employment
Source: Self-asserted source
Diogo M. Lourenço

Fundação Champalimaud: Lisboa, PT

2017-01 to 2017-12 | Trainee Researcher (Lima Lab - Neuroethology)
Employment
Source: Self-asserted source
Diogo M. Lourenço

Institute of Psychiatry Psychology and Neuroscience Department of Basic and Clinical Neuroscience: London, London, GB

2016-01 to 2016-09 | Graduate researcher (Hirth Lab - Neural Circuits and Behaviour)
Employment
Source: Self-asserted source
Diogo M. Lourenço

Guy's and St Thomas' NHS Foundation Trust: London, GB

2015-01 to 2015-06 | Graduate researcher (Division of Women's Health)
Employment
Source: Self-asserted source
Diogo M. Lourenço

Instituto Gulbenkian de Ciencia: Oeiras, PT

2014-03 to 2014-06 | Undergraduate researcher (Beldade Lab - Variation: Development and Selection)
Employment
Source: Self-asserted source
Diogo M. Lourenço

Universidade de Lisboa Faculdade de Ciências: Lisboa, Lisboa, PT

2013-04 to 2013-08 | Volunteer (TEC Labs - BioFIG)
Employment
Source: Self-asserted source
Diogo M. Lourenço

Education and qualifications (3)

Universidade de Lisboa Faculdade de Medicina: Lisboa, Lisboa, PT

2018-04 to 2023-12 | PhD (Biomedical Sciences - Neuroscience)
Education
Source: Self-asserted source
Diogo M. Lourenço

King's College London: London, London, GB

2014-10 to 2016-12 | MSc Neuroscience
Education
Source: Self-asserted source
Diogo M. Lourenço

Universidade de Lisboa Faculdade de Ciências: Lisboa, Lisboa, PT

2011-09 to 2014-06 | BSc in Biology
Education
Source: Self-asserted source
Diogo M. Lourenço

Professional activities (4)

International Society for Neurochemistry: Geneva, CH

Travel Award to attend ISN-ASN Meeting in Montréal from 4-8 August, 2019
Distinction
Source: Self-asserted source
Diogo M. Lourenço

International Society for Neurochemistry: Geneva, CH

2019-02 to present
Membership
Source: Self-asserted source
Diogo M. Lourenço

Sociedade Portuguesa de Células Estaminais e Terapia Celular: Porto, Porto, PT

2019 to present
Membership
Source: Self-asserted source
Diogo M. Lourenço

Sociedade Portuguesa de Neurociência: Lisboa, PT

2018-05 to present
Service
Source: Self-asserted source
Diogo M. Lourenço

Funding (1)

Role of non-psychotic cannabinoids in neural stem cells differentiation: relevance for Multiple Sclerosis

2018-04 to 2023-12 | Grant
Fundação para a Ciência e a Tecnologia (Lisbon, PT)
GRANT_NUMBER:

PD/BD/141784/2018

Source: Self-asserted source
Diogo M. Lourenço
grade
Preferred source (of 2)‎

Works (39)

Cannabinoid type 2 receptor inhibition enhances the antidepressant and proneurogenic effects of physical exercise after chronic stress

Translational Psychiatry
2024 | Journal article
Contributors: Rodrigues, R. S.; Moreira, J. B.; Mateus, J. M.; Barateiro, A.; Paulo, S. L.; Vaz, S. H.; Lourenco, D. M.; Ribeiro, F. F.; Soares, R.; Loureiro-Campos, E. et al.
Source: check_circle
Web of Science Researcher Profile Sync
grade
Preferred source (of 2)‎

Lineage-specific changes in mitochondrial properties during neural stem cell differentiation

Life Science Alliance
2024-07 | Journal article
Contributors: Rita Soares; Diogo M Lourenço; Isa F Mota; Ana M Sebastião; Sara Xapelli; Vanessa A Morais
Source: check_circle
Crossref

Cannabidivarin and its neurogenic potential as a novel target for Rett syndrome

Journal of Neurochemistry
2023 | Journal article
Contributors: Lourenco, Diogo M.; Zavalko, Svitlana; Santos, Sonia Sa; Mateus, Joana M.; Rodrigues, Rui S.; Miranda-Lourenco, Catarina; Sebastiao, Ana M.; Mouro, Francisco M.; Sola, Susana; Diogenes, Maria Jose et al.
Source: check_circle
Web of Science Researcher Profile Sync

Cannabidivarin and its neurogenic potential as a novel target for Rett syndrome

Journal of Neurochemistry
2023 | Journal article
Contributors: Lourenco, Diogo M.; Zavalko, Svitlana; Santos, Sonia Sa; Mateus, Joana M.; Rodrigues, Rui S.; Miranda-Lourenco, Catarina; Sebastiao, Ana M.; Mouro, Francisco M.; Sola, Susana; Diogenes, Maria Jose et al.
Source: check_circle
Web of Science Researcher Profile Sync

Cannabinoid type 2 receptor inhibition enhances the antidepressant and proneurogenic effects of physical exercise after chronic stress

BioRxiv
2023 | Journal article
Contributors: Rodrigues, Rui Miguel Silva; Moreira, Joao Baptista; Vaz, Sandra Cristina Henriques; Barateiro, Andreia Pereira Barateiro; Paulo, Sara Raquel Landeira Nabais; Mateus, Joana Moura; Lourenco, Diogo Miguel da Palma; Ribeiro, Filipa Ferreira Cunha; Loureiro-Campos, Eduardo Manuel; Bielefeld, Pascal et al.
Source: check_circle
Web of Science Researcher Profile Sync
grade
Preferred source (of 4)‎

CANNABINOID TYPE 2 RECEPTOR INHIBITION ENHANCES THE ANTIDEPRESSANT AND PRONEUROGENIC EFFECTS OF PHYSICAL EXERCISE AFTER CHRONIC STRESS

Wound Repair and Regeneration
2023 | Journal article
Contributors: Rodrigues, R. S.; Moreira, J. B.; Vaz, S. H.; Barateiro, A.; Paulo, S. L.; Mateus, J. M.; Lourenco, D. M.; Ribeiro, F. F.; Loureiro-Campos, E.; Bielefeld, P. et al.
Source: check_circle
Web of Science Researcher Profile Sync

Countering chronic stress with cannabinoid type 2 receptors and physical exercise: A neurogenic focus

Journal of Neurochemistry
2023 | Journal article
Contributors: Rodrigues, Rui S.; Moreira, Joao B.; Barateiro, Andreia; Vaz, Sandra; Paulo, Sara L.; Mateus, Joana M.; Lourenco, Diogo M.; Ribeiro, Filipa F.; Campos-Loureiro, Eduardo; Bielefeld, Pascal et al.
Source: check_circle
Web of Science Researcher Profile Sync

Run, brain, run! In vitro and in vivo modulation of adult oligodendrogenesis by BDNF

Journal of Neurochemistry
2023 | Journal article
Contributors: Mateus, Joana M.; Moreira, Joao B.; Lourenco, Diogo M.; Sebastiao, Ana M.; Dawson, Neil; Xapelli, Sara
Source: check_circle
Web of Science Researcher Profile Sync

Uncovering mitochondrial properties as novel targets for neural stem cell differentiation in the subventricular zone

Journal of Neurochemistry
2023 | Journal article
Contributors: Soares, Rita; Mota, Isa F.; Lourenco, Diogo M.; Sebastiao, Ana M.; Xapelli, Sara; Morais, Vanessa A.
Source: check_circle
Web of Science Researcher Profile Sync

Uncovering mitochondrial properties as novel targets for neural stem cell differentiation in the subventricular zone

Journal of Neurochemistry
2023 | Journal article
Contributors: Soares, Rita; Mota, Isa F.; Lourenco, Diogo M.; Sebastiao, Ana M.; Xapelli, Sara; Morais, Vanessa A.
Source: check_circle
Web of Science Researcher Profile Sync

Unravelling a novel role for cannabidivarin in the modulation of subventricular zone postnatal neurogenesis

European Journal of Pharmacology
2023 | Journal article
Contributors: Lourenco, Diogo M.; Soares, Rita; Sa-Santos, Sonia; Mateus, Joana M.; Rodrigues, Rui S.; Moreira, Joao B.; Vaz, Sandra H.; Sebastia, Ana M.; Sola, Susana; Xapelli, Sara
Source: check_circle
Web of Science Researcher Profile Sync
grade
Preferred source (of 2)‎

Unravelling a novel role for Cannabidivarin in the modulation of subventricular zone postnatal neurogenesis

BioRxiv
2023 | Journal article
Contributors: Lourenco, Diogo M.; Soares, Rita; Santos, Sonia Sa; Mateus, Joana M; Rodrigues, Rui S; Moreira, Joao B; Vaz, Sandra H; Sebastiao, Ana M; Sola, Susana; Xapelli, Sara
Source: check_circle
Web of Science Researcher Profile Sync
grade
Preferred source (of 3)‎

BDNF, adenosine A2AR and cannabinoid receptors: a triad of regulators of postnatal oligodendrogenesis

Journal of Neurochemistry
2022 | Journal article
Contributors: Mateus, Joana M.; Moreira, Joao B.; Lourenco, Diogo M.; Sebastiao, Ana M.; Dawson, Neil; Xapelli, Sara
Source: check_circle
Web of Science Researcher Profile Sync

Cannabidivarin and neural stem cells, a new hope for Rett syndrome?

Journal of Neurochemistry
2022 | Journal article
Contributors: Lourenco, Diogo Miguel; Zavalko, Svitlana; Soares, Rita; Mateus, Joana Moura; Rodrigues, Rui Silva; Miranda-Lourenco, Catarina; Sebastiao, Ana; Mouro, Francisco; Diogenes, Maria Jose; Xapelli, Sara
Source: check_circle
Web of Science Researcher Profile Sync

Characterizing the role of mitochondrial dynamics in postnatal neural stem cell fate

Journal of Neurochemistry
2022 | Journal article
Contributors: Soares, Rita; Mota, Isa F.; Lourenco, Diogo M.; Sebastiao, Ana M.; Xapelli, Sara; Morais, Vanessa A.
Source: check_circle
Web of Science Researcher Profile Sync

Searching for modulators of adult oligodendrogenesis

Glia
2021 | Journal article
Contributors: Mateus, J. M.; Lourenco, D. M.; Sebastiao, A. M.; Xapelli, S.
Source: check_circle
Web of Science Researcher Profile Sync

The neurosphere assay: an effective <i>in vitro</i> technique to study neural stem cells

Neural Regeneration Research
2021 | Journal article
Contributors: Soares, Rita; Ribeiro, Filipa F.; Lourenco, Diogo M.; Rodrigues, Rui S.; Moreira, Joao B.; Sebastiao, Ana M.; Morais, Vanessa A.; Xapelli, Sara
Source: check_circle
Web of Science Researcher Profile Sync
grade
Preferred source (of 2)‎

Isolation and Expansion of Neurospheres from Postnatal (P1-3) Mouse Neurogenic Niches

Journal of Visualized Experiments
2020 | Journal article
SOURCE-WORK-ID:

cv-prod-id-1724642

Contributors: Rita Soares; Filipa F. Ribeiro; Lourenço, Diogo M.; Rui S. Rodrigues; João B. Moreira; Ana M. Sebastião; Vanessa A. Morais; Sara Xapelli
Source: check_circle
CIÊNCIAVITAE

Isolation and Expansion of Neurospheres from Postnatal (P1-3) Mouse Neurogenic Niches

Journal of Visualized Experiments
2020 | Journal article
Contributors: Soares, Rita; Ribeiro, Filipa F.; Lourenco, Diogo M.; Rodrigues, Rui S.; Moreira, Joao B.; Sebastiao, Ana M.; Morais, Vanessa A.; Xapelli, Sara
Source: check_circle
Web of Science Researcher Profile Sync
grade
Preferred source (of 2)‎

Neural Stem Cells and Cannabinoids in the Spotlight as Potential Therapy for Epilepsy

International Journal of Molecular Sciences
2020 | Journal article
Contributors: Lourenco, Diogo M.; Ribeiro-Rodrigues, Leonor; Sebastiao, Ana M.; Diogenes, Maria J.; Xapelli, Sara
Source: check_circle
Web of Science Researcher Profile Sync
grade
Preferred source (of 4)‎

Not just nociception: regulation of postnatal neurogenesis by TRPV1

ScienceOpen Posters
2020-07 | Conference poster
Contributors: Sara Xapelli; Ana Sebastião; Rui Rodrigues; Rita Soares; Diogo Lourenço
Source: check_circle
ScienceOpen, Inc.
grade
Preferred source (of 2)‎

Mitochondrial Dynamics: impact on adult neural stem cell fate

2020-07-10 | Preprint
Contributors: Rita Soares; Diogo M. Lourenço; Jonathan Verduyckt; Ana M. Sebastião; Sara Xapelli; Vanessa A. Morais
Source: check_circle
Crossref

Cannabidivarin, capsaicin and the multiple fates of neural stem cells

Journal of Neurochemistry
2019 | Journal article
Contributors: Lourenco, D.; Soares, R.; Rodrigues, R.; Sebastiao, A.; Xapelli, S.
Source: check_circle
Web of Science Researcher Profile Sync

Cannabinoid actions on Rett Syndrome’s associated deficits and its effect on post-natal Neurogenesis in a female MECP2-mutant mouse mode

5th Meeting of the Mind-Brain College of the University of Lisbon
2019-11 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-1816654

Contributors: Zavalko S; Mouro FM; Diogo M. Lourenço; Miranda-Lourenço C; Ana M. Sebastião; Diógenes, MJ; Xapelli Sara
Source: check_circle
CIÊNCIAVITAE

Modulation of neural stem cells by Cannabidivarin and Capsaicin

5th Meeting of the Mind-Brain College of the University of Lisbon
2019-11 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-1723528

Contributors: Lourenço, Diogo M.; Rita Soares; Rui S. Rodrigues; Ana M. Sebastião; Sara Xapelli
Source: check_circle
CIÊNCIAVITAE

Cannabidivarin and Capsaicin as modulators of neural stem cells

11th International Meeting of Portuguese Society for Stem Cells and Cell Therapies
2019-10 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-1723856

Contributors: Lourenço, Diogo M.; Rita Soares; Rui S. Rodrigues; Ana M. Sebastião; Sara Xapelli
Source: check_circle
CIÊNCIAVITAE

Subventricular zone neurogenesis regulation by exercise factors and cannabinoid type 2 receptor

iMed Conference 11.0
2019-10 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-1817230

Contributors: João B. Moreira; Rui S. Rodrigues; Diogo M. Lourenço; Ana M. Sebastião; Sara Xapelli
Source: check_circle
CIÊNCIAVITAE

Unveiling the role of cannabinoid type 2 receptor and exercise-regulated neurotrophic factors in subventricular zone neurogenesis

11th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies
2019-10-09 | Conference abstract
SOURCE-WORK-ID:

cv-prod-id-1817825

Contributors: João B. Moreira; Rui S. Rodrigues; Diogo M. Lourenço; Ana M. Sebastião; Sara Xapelli
Source: check_circle
CIÊNCIAVITAE

Cannabidivarin, capsaicin and the multiple fates of neural stem cells

ISN-ASN Meeting 2019 – Montréal, Canada
2019-07 | Conference abstract
SOURCE-WORK-ID:

cv-prod-id-1723980

Contributors: Lourenço, Diogo M.; Rita Soares; Rui S. Rodrigues; Ana M. Sebastião; Sara Xapelli
Source: check_circle
CIÊNCIAVITAE
grade
Preferred source (of 3)‎

Cannabidivarin and Capsaicin promote neuronal differentiation of neural stem cells

IV Eurogenesis Meeting – Bordeaux, France
2019-06 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-1724260

Contributors: Lourenço, Diogo M.; Rita Soares; Rui S. Rodrigues; Ana M. Sebastião; Sara Xapelli
Source: check_circle
CIÊNCIAVITAE

The effect of the non-psychoactive cannabinoid Cannabidivarin and TRPV1 agonist Capsaicin on neural stem cell differentiation

XVI Sociedade Portuguesa de Neurociências SPN - Meeting 2019
2019-06 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-1724385

Contributors: Lourenço, Diogo M.; Rita Soares; Rui S. Rodrigues; Ana M. Sebastião; Sara Xapelli
Source: check_circle
CIÊNCIAVITAE

Modulation of subventricular zone neurogenesis by cannabinoid type 2 receptor and “exercise-regulated” neurotrophic factors

XVI Meeting of the Portuguese Society for Neuroscience (SPN2019)
2019-05 | Conference abstract
SOURCE-WORK-ID:

cv-prod-id-657979

Contributors: João B. Moreira; Rui S. Rodrigues; Lourenço, Diogo M.; Ana M. Sebastião; Sara Xapelli
Source: check_circle
CIÊNCIAVITAE
grade
Preferred source (of 3)‎

Neurons or Oligodendrocytes: The effect of Cannabidivarin and Capsaicin on the fate of neural stem/progenitor cells

XIII CAML PhD Students' Meeting 2019
2019-05 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-1724529

Contributors: Lourenço, Diogo M.; Rita Soares; Rui S. Rodrigues; Ana M. Sebastião; Sara Xapelli
Source: check_circle
CIÊNCIAVITAE

Regulation of neural stem cell fate by Cannabidivarin and Capsaicin

IV Portuguese Glial Network Symposium
2019-05 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-1724439

Contributors: Lourenço, Diogo M.; Rita Soares; Rui S. Rodrigues; Ana M. Sebastião; Sara Xapelli
Source: check_circle
CIÊNCIAVITAE

Cannabinoid Actions on Neural Stem Cells: Implications for Pathophysiology

Molecules
2019-04-05 | Journal article
Source: Self-asserted source
Diogo M. Lourenço
grade
Preferred source (of 6)‎

Role of non-psychoactive cannabinoids in neural stem cell differentiation: relevance for neurodegenerative diseases

III SynaNet Meeting
2018-12 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-332408

Contributors: Lourenço, Diogo M.; Rodrigues, Rui S.; Sebastião, A. M.; Xapelli, S.
Source: check_circle
CIÊNCIAVITAE

The Influence of Caffeine on Subventricular Zone and Dentate Gyrus Neurogenesis

4th Meeting of the Mind-Brain College of the University of Lisbon
2018-11 | Conference poster
SOURCE-WORK-ID:

cv-prod-id-1817747

Contributors: Marit A. Vink; Diogo M. Lourenço; Rui S. Rodrigues; Ana M. Sebastião; Luísa V. Lopes; Sara Xapelli
Source: check_circle
CIÊNCIAVITAE
grade
Preferred source (of 3)‎

Modelling Parkinson’s Disease in Drosophila: a “prion-like” behaviour of Alpha-Synuclein?

King's College London
2016-09 | Dissertation or Thesis
SOURCE-WORK-ID:

cv-prod-id-332378

SOURCE-WORK-ID:

cv-prod-id-332379

OTHER-ID:

MSc Poster

OTHER-ID:

MSc Thesis

Source: Self-asserted source
Diogo M. Lourenço
grade
Preferred source (of 4)‎

Cellular and molecular mechanisms underlying wound-induced pigmentation pattern formation in the butterfly Bicyclus anynana;

Faculdade de Ciências da Universidade de Lisboa
2014-06 | Report
OTHER-ID:

Project Report

Source: Self-asserted source
Diogo M. Lourenço
grade
Preferred source (of 3)‎