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Works (26)

PAX3-FOXO1 dictates myogenic reprogramming and rhabdomyosarcoma identity in endothelial progenitors

Nature Communications
2023-11-15 | Journal article
DOI: 10.1038/s41467-023-43044-1
Contributors: Madeline B. Searcy; Randolph K. Larsen, IV; Bradley T. Stevens; Yang Zhang; Hongjian Jin; Catherine J. Drummond; Casey G. Langdon; Katherine E. Gadek; Kyna Vuong; Kristin B. Reed et al.
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Nuclear PTEN’s Functions in Suppressing Tumorigenesis: Implications for Rare Cancers

Biomolecules
2023-01-30 | Journal article
DOI: 10.3390/biom13020259
Contributors: Casey G. Langdon
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Rhabdomyosarcoma: visions through the looking glass

Clinical Cancer Research
2022 | Journal article
WOSUID: WOS:000860547500011
Contributors: Hatley, Mark E.; Langdon, Casey G.; Gadek, Katherine E.; Garcia, Matthew R.; Drummond, Catherine J.; Hanna, Jason A.; Jin, Hongjian E.; Rehg, Jerold E.
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Synthetic essentiality between PTEN and core dependency factor PAX7 dictates rhabdomyosarcoma identity

Cancer Research
2022 | Journal article
WOSUID: WOS:000892509506595
Contributors: Langdon, Casey G.; Gadek, Katherine E.; Garcia, Matthew R.; Evans, Myron K.; Reed, Kristin B.; Bush, Madeline; Hanna, Jason A.; Drummond, Catherine J.; Maguire, Matthew C.; Leavey, Patrick J. et al.
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Genetic context of oncogenic drivers dictates vascular sarcoma development in aP2‐Cre mice

The Journal of Pathology
2022-05 | Journal article
DOI: 10.1002/path.5873
Contributors: Jason A Hanna; Casey G Langdon; Matthew R Garcia; Annaleigh Benton; Nadia A Lanman; David Finkelstein; Jerold E Rehg; Mark E Hatley
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Synthetic essentiality between PTEN and core dependency factor PAX7 dictates rhabdomyosarcoma identity

Nature Communications
2021 | Journal article
DOI: 10.1038/S41467-021-25829-4
WOSUID: WOS:000697033200020
Contributors: Langdon, Casey G.; Gadek, Katherine E.; Garcia, Matthew R.; Evans, Myron K.; Reed, Kristin B.; Bush, Madeline; Hanna, Jason A.; Drummond, Catherine J.; Maguire, Matthew C.; Leavey, Patrick J. et al.
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Synthetic essentiality between PTEN and core dependency factor PAX7 dictates rhabdomyosarcoma indentity

Cancer Research
2021 | Journal article
WOSUID: WOS:000680263506358
Contributors: Langdon, Casey G.; Gadek, Katherine E.; Garcia, Matthew R.; Reed, Kristin B.; Bush, Madeline; Hanna, Jason A.; Drummond, Catherine J.; Maguire, Matthew C.; Leavey, Patrick J.; Finkelstein, David et al.
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The perfect PTEN - transcriptional regulation by PTEN dictates sarcoma identity

Molecular & Cellular Oncology
2021 | Journal article
DOI: 10.1080/23723556.2021.2002120
WOSUID: WOS:000721155600001
Contributors: Langdon, Casey G.; Hatley, Mark E.
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Inhibition of isoprenylation synergizes with MAPK blockade to prevent growth in treatment-resistant melanoma, colorectal, and lung cancer

Pigment Cell & Melanoma Research: The Official Journal of the International Federation of Pigment Cell Societies and the Society for Melanoma Research
2019 | Journal article
DOI: 10.1111/PCMR.12742
WOSUID: WOS:000459883000007
Contributors: Theodosakis, Nicholas; Langdon, Casey G.; Micevic, Goran; Krykbaeva, Irina; Means, Robert E.; Stern, David F.; Bosenberg, Marcus W.
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Modeling the vascular sarcoma spectrum with genetically engineered mice

Cancer Research
2019 | Journal article
DOI: 10.1158/1538-7445.AM2019-4631
WOSUID: WOS:000488279404504
Contributors: Hanna, Jason A.; Langdon, Casey G.; Garcia, Matthew R.; Finkelstein, David; Rehg, Jerold E.; Hatley, Mark E.
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Combinatorial Screening of Pancreatic Adenocarcinoma Reveals Sensitivity to Drug Combinations Including Bromodomain Inhibitor Plus Neddylation Inhibitor

Molecular Cancer Therapeutics
2017 | Journal article
DOI: 10.1158/1535-7163.MCT-16-0794
WOSUID: WOS:000402559300007
Contributors: Langdon, Casey G.; Platt, James T.; Means, Robert E.; Iyidogan, Pinar; Mamillapalli, Ramanaiah; Klein, Michael; Held, Matthew A.; Lee, Jong Woo; Koo, Ja Seok; Hatzis, Christos et al.
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Inhibition of isoprenylation synergizes with MAPK blockade to prevent growth in treatment-resistant melanoma

Journal of Investigative Dermatology
2017 | Journal article
DOI: 10.1016/J.JID.2017.02.814
WOSUID: WOS:000406862400783
Contributors: Theodosakis, N.; Langdon, C.; Micevic, G.; Stern, D.; Bosenberg, M.
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p90RSK Blockade Inhibits Dual BRAF and MEK Inhibitor-Resistant Melanoma by Targeting Protein Synthesis

Journal of Investigative Dermatology
2017 | Journal article
DOI: 10.1016/J.JID.2016.12.033
WOSUID: WOS:000411210000097
Contributors: Theodosakis, Nicholas; Micevic, Goran; Langdon, Casey G.; Ventura, Alessandra; Means, Robert; Stern, David F.; Bosenberg, Marcus W.
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Systematic Drug Screening Identifies Tractable Targeted Combination Therapies in Triple-Negative Breast Cancer

Cancer Research
2017 | Journal article
DOI: 10.1158/0008-5472.CAN-16-1901
WOSUID: WOS:000393190600033
Contributors: Wali, Vikram B.; Langdon, Casey G.; Held, Matthew A.; Platt, James T.; Patwardhan, Gauri A.; Safonov, Anton; Aktas, Bilge; Pusztai, Lajos; Stern, David F.; Hatzis, Christos
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Novel combination therapies for triple negative breast cancer identified by high-throughput screening

Cancer Research
2016 | Journal article
DOI: 10.1158/1538-7445.SABCS15-P6-13-06
WOSUID: WOS:000375622403355
Contributors: Wall, V. B.; Langdon, C. G.; Held, M. A.; Platt, J. T.; Safonov, A.; Aktas, B.; Stern, D. F.; Pusztai, L.; Hatzis, C.
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Debio 1143 synergizes with taxanes, topoisomerase and bromodomain inhibitors to inhibit growth of lung adenocarcinoma

Cancer Research
2015 | Journal article
DOI: 10.1158/1538-7445.AM2015-2529
WOSUID: WOS:000371578505121
Contributors: Langdon, Casey G.; Wiedemann, Norbert; Held, Matthew A.; Platt, James T.; Mamillapalli, Ramanaiah; Iyidogan, Pinar; Theodosakis, Nicholas; Levy, Frederic; Robichon, Denis; Zanna, Claudio et al.
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PDK1 and SGK3 Contribute to the Growth of BRAF-Mutant Melanomas and Are Potential Therapeutic Targets

Cancer Research
2015 | Journal article
DOI: 10.1158/0008-5472.CAN-14-2785
WOSUID: WOS:000351948900026
Contributors: Scortegagna, Marzia; Lau, Eric; Zhang, Tongwu; Feng, Yongmei; Sereduk, Chris; Yin, Hongwei; De, Surya K.; Meeth, Katrina; Platt, James T.; Langdon, Casey G. et al.
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SMAC mimetic Debio 1143 synergizes with taxanes, topoisomerase inhibitors and bromodomain inhibitors to impede growth of lung adenocarcinoma cells

Oncotarget
2015 | Journal article
DOI: 10.18632/ONCOTARGET.6138
WOSUID: WOS:000366113200036
Contributors: Langdon, Casey G.; Wiedemann, Norbert; Held, Matthew A.; Mamillapalli, Ramanaiah; Iyidogan, Pinar; Theodosakis, Nicholas; Platt, James T.; Levy, Frederic; Vuagniaux, Gregoire; Wang, Shaomeng et al.
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The broad-spectrum receptor tyrosine kinase inhibitor dovitinib suppresses growth of <i>BRAF</i>-mutant melanoma cells in combination with other signaling pathway inhibitors

Pigment Cell & Melanoma Research: The Official Journal of the International Federation of Pigment Cell Societies and the Society for Melanoma Research
2015 | Journal article
DOI: 10.1111/PCMR.12376
WOSUID: WOS:000356362600009
Contributors: Langdon, Casey G.; Held, Matthew A.; Platt, James T.; Meeth, Katrina; Iyidogan, Pinar; Mamillapalli, Ramanaiah; Koo, Andrew B.; Klein, Michael; Liu, Zongzhi; Bosenberg, Marcus W. et al.
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ACTIVITY OF IAP ANTAGONIST DEBIO 1143 AS A MONOTHERAPY AND IN COMBINATION WITH STANDARD OF CARE AGENTS IN MODELS OF HUMAN LUNG CANCER OF DIFFERENT HISTOTYPES

Journal of Thoracic Oncology
2014 | Journal article
WOSUID: WOS:000341688500046
Contributors: Wiedemann, N.; Langdon, C. G.; Held, M. A.; Platt, J. T.; Zanna, C.; Sorensen, M.; Wang, S.; Bosenberg, M. W.; Stern, D. F.; Vuagniaux, G.
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Debio 1143, an oral antagonist of the inhibitor of apoptosis proteins, synergistically enhances the effects of multiple standard of care agents in human lung cancer models

Cancer Research
2014 | Journal article
DOI: 10.1158/1538-7445.AM2014-5441
WOSUID: WOS:000349910204358
Contributors: Langdon, Casey G.; Wiedemann, Norbert; Held, Mathew A.; Platt, James T.; Levy, Frederic; Robichon, Denis; Zanna, Claudio; Vuagniaux, Gregoire; Sorensen, Mel; Wang, Shaomeng et al.
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Identification of synergistic drug combinations with the oral HSP90 inhibitor Debio 0932 in non-small cell lung cancer and renal cell cancer

Cancer Research
2014 | Journal article
DOI: 10.1158/1538-7445.AM2014-1792
WOSUID: WOS:000349906902011
Contributors: Langdon, Casey G.; Wiedemann, Norbert; Hajjami, Helene Maby-El; Held, Mathew A.; Platt, James T.; Vuagniaux, Gregoire; Bosenberg, Marcus W.; Stern, David F.; Levy, Frederic
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A drug combination screen identifies taxanes as synergistic agents with the oral IAP inhibitor Debio 1143 in non-small cell lung cancer cells

Molecular Cancer Therapeutics
2013 | Journal article
DOI: 10.1158/1535-7163.TARG-13-A16
WOSUID: WOS:000209496800015
Contributors: Langdon, Casey G.; Wiedemann, Norbert; Held, Mathew A.; Platt, James T.; Levy, Frederic; Zanna, Claudio; Vuagniaux, Gregoire; Sorensen, Mel; Wang, Shaomeng; Bosenberg, Marcus W. et al.
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Dovitinib as a single-agent or in combination with other small molecule inhibitors for mutant BRAF melanomas

Molecular Cancer Therapeutics
2013 | Journal article
DOI: 10.1158/1535-7163.TARG-13-B275
WOSUID: WOS:000209496800440
Contributors: Langdon, Casey G.; Held, Matthew A.; Koo, Andrew B.; Klein, Michael; Liu, Zongzhi; Platt, James T.; Stern, David F.
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Genotype-Selective Combination Therapies for Melanoma Identified by High-Throughput Drug Screening

Cancer Discovery
2013 | Journal article
DOI: 10.1158/2159-8290.CD-12-0408
WOSUID: WOS:000313642900024
Contributors: Held, Matthew A.; Langdon, Casey G.; Platt, James T.; Graham-Steed, Tisheeka; Liu, Zongzhi; Chakraborty, Ashok; Bacchiocchi, Antonella; Koo, Andrew; Haskins, Jonathan W.; Bosenberg, Marcus W. et al.
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Identification of effective genotype-selective drug combinations in melanoma

Cancer Research
2012 | Journal article
DOI: 10.1158/1538-7445.AM2012-5088
WOSUID: WOS:000209701606292
Contributors: Held, Matthew; Langdon, Casey; Platt, James; Steed, Tisheeka; Chakraborty, Ashok; Bachiocchi, Antonella; Liu, Zonghzhi; Bosenberg, Marcus; Stern, David F.
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Peer review (23 reviews for 4 publications/grants)

Review activity for Cancers. (5)
Review activity for Cells. (5)
Review activity for Clinical and translational medicine. (2)
Review activity for International journal of molecular sciences. (11)
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