Personal information

No personal information available

Activities

Collapse all

Works (33)

A Multipurpose First-in-Human Study With the Novel CXCR7 Antagonist ACT-1004-1239 Using CXCL12 Plasma Concentrations as Target Engagement Biomarker.

Clinical pharmacology and therapeutics
2021-01-06 | Journal article
DOI: 10.1002/cpt.2154
PMID: 33406277
Source: Self-asserted source
Daniel Strasser

Immunoaffinity Targeted Mass Spectrometry Analysis of Human Plasma Samples Reveals an Imbalance of Active and Inactive CXCL10 in Primary Sjögren's Syndrome Disease Patients.

Journal of proteome research
2020-09-15 | Journal article
DOI: 10.1021/acs.jproteome.0c00494
PMID: 32870689
Source: Self-asserted source
Daniel Strasser

Preclinical to clinical translation of cenerimod, a novel S1P<sub>1</sub> receptor modulator, in systemic lupus erythematosus.

RMD open
2020-09-01 | Journal article
DOI: 10.1136/rmdopen-2020-001261
PMID: 32917831
PMC: PMC7722385
Source: Self-asserted source
Daniel Strasser

Impact of high-altitude therapy on type-2 immune responses in asthma patients.

Allergy
2019-11-03 | Journal article
DOI: 10.1111/all.13967
PMID: 31267528
Source: Self-asserted source
Daniel Strasser

Pharmacokinetics, pharmacodynamics, tolerability and prediction of clinically effective dose of ACT-774312: A novel CRTH2 antagonist.

Basic & clinical pharmacology & toxicology
2019-02-11 | Journal article
DOI: 10.1111/bcpt.13197
PMID: 30589994
Source: Self-asserted source
Daniel Strasser

Attenuation of murine sclerodermatous models by the selective S1P1 receptor modulator cenerimod.

Scientific reports
2019-01-24 | Journal article
DOI: 10.1038/s41598-018-37074-9
PMID: 30679645
PMC: PMC6345830
Source: Self-asserted source
Daniel Strasser

Pharmacological Characterization of Aprocitentan, a Dual Endothelin Receptor Antagonist, Alone and in Combination with Blockers of the Renin Angiotensin System, in Two Models of Experimental Hypertension.

The Journal of pharmacology and experimental therapeutics
2019-01-08 | Journal article
DOI: 10.1124/jpet.118.253864
PMID: 30622171
Source: Self-asserted source
Daniel Strasser

Eosinophilic Esophagitis: Relevance of Mast Cell Infiltration.

Histopathology
2018-05 | Journal article
DOI: 10.1111/his.13653
PMID: 29772120
Contributors: Strasser DS; Seger S; Bussmann C; Pierlot GM; Groenen PMA; Stalder AK; Straumann A
Source: Self-asserted source
Daniel Strasser via Europe PubMed Central

Activation of IL5R and CRTH2 on human eosinophils elicit a similar molecular response and reveal a synergistic effect

European Journal of Molecular and Clinical Medicine
2018-04-16 | Journal article
DOI: 10.5334/ejmcm.1
Source: Self-asserted source
Daniel Strasser

Granulomatous lung inflammation is nanoparticle type-dependent.

Experimental lung research
2018-02 | Journal article
DOI: 10.1080/01902148.2017.1412541
PMID: 29324063
Contributors: Pacheco Y; Ponchon M; Lebecque S; Calender A; Bernaudin JF; Valeyre D; Iglarz M; Strasser DS; Studer R; Freti D et al.
Source: Self-asserted source
Daniel Strasser via Europe PubMed Central

Monitoring inflammatory heterogeneity with multiple biomarkers for multidimensional endotyping of asthma.

The Journal of allergy and clinical immunology
2018-01 | Journal article
DOI: 10.1016/j.jaci.2017.08.027
PMID: 28987809
Contributors: Agache I; Strasser DS; Pierlot GM; Farine H; Izuhara K; Akdis CA
Source: Self-asserted source
Daniel Strasser via Europe PubMed Central

Comprehensive characterization of asthma patients using bayesian networks

European respiratory society
2017-09-10 | Conference poster
Source: Self-asserted source
Daniel Strasser

Endothelin ETA Receptor Blockade, by Activating ETB Receptors, Increases Vascular Permeability and Induces Exaggerated Fluid Retention.

The Journal of pharmacology and experimental therapeutics
2017-05 | Journal article
DOI: 10.1124/jpet.116.234930
PMID: 28223322
Contributors: Vercauteren M; Trensz F; Pasquali A; Cattaneo C; Strasser DS; Hess P; Iglarz M; Clozel M
Source: Self-asserted source
Daniel Strasser via Europe PubMed Central

Biomarker-guided clinical development of the first-in-class anti-inflammatory FPR2/ALX agonist ACT-389949.

British journal of clinical pharmacology
2017-03 | Journal article
DOI: 10.1111/bcp.13149
PMID: 27730665
PMC: PMC5306489
Contributors: Stalder AK; Lott D; Strasser DS; Cruz HG; Krause A; Groenen PM; Dingemanse J
Source: Self-asserted source
Daniel Strasser via Europe PubMed Central

Modeling the Effect of the Selective S1P1 Receptor Modulator Ponesimod on Subsets of Blood Lymphocytes.

Pharmaceutical research
2017-03 | Journal article
DOI: 10.1007/s11095-016-2087-x
PMID: 28028771
Contributors: Lott D; Krause A; Seemayer CA; Strasser DS; Dingemanse J; Lehr T
Source: Self-asserted source
Daniel Strasser via Europe PubMed Central

Serum IL-5 and IL-13 consistently serve as the best predictors for the blood eosinophilia phenotype in adult asthmatics.

Allergy
2016-08 | Journal article
DOI: 10.1111/all.12906
PMID: 27060452
Contributors: Agache I; Strasser DS; Klenk A; Agache C; Farine H; Ciobanu C; Groenen PM; Akdis CA
Source: Self-asserted source
Daniel Strasser via Europe PubMed Central

Pharmacokinetic/Pharmacodynamic Modelling of Receptor Internalization with CRTH2 Antagonists to Optimize Dose Selection.

Clinical pharmacokinetics
2016-07 | Journal article
DOI: 10.1007/s40262-015-0354-3
PMID: 26692193
Contributors: Krause A; Zisowsky J; Strasser DS; Gehin M; Sidharta PN; Groenen PMA; Dingemanse J
Source: Self-asserted source
Daniel Strasser via Europe PubMed Central

Identification of novel candidate biomarkers for systemic lupus erythematosus patient characterization

Annals of the rheumatic diseases
2015-09-02 | Journal article
DOI: annrheumdis-2015-eular.4708
Source: Self-asserted source
Daniel Strasser

A novel CRTH2 antagonist: Single- and multiple-dose tolerability, pharmacokinetics, and pharmacodynamics of ACT-453859 in healthy subjects.

Journal of clinical pharmacology
2015-07 | Journal article
DOI: 10.1002/jcph.478
PMID: 25655470
Contributors: Géhin M; Strasser DS; Zisowsky J; Farine H; Groenen PM; Dingemanse J; Sidharta PN
Source: Self-asserted source
Daniel Strasser via Europe PubMed Central

Development of a decision-making biomarker for CRTH2 antagonism in clinical studies

New Horizons in Translational Medicine
2015-06-12 | Journal article
DOI: j.nhtm.2015.05.001
Source: Self-asserted source
Daniel Strasser

Evaluation of the CRTH2 pathway as therapeutic approach for eosinophilic esophagitis

Digestive Disease Week 2015
2015-05-17 | Conference poster
Source: Self-asserted source
Daniel Strasser

Therapeutic effect of macitentan, a novel dual endothelin receptor antagonist, on right ventricular structure and function in pulmonary arterial hypertensive rats

American Thoraic Society 2015
2015-05-17 | Conference poster
Source: Self-asserted source
Daniel Strasser

Genetic screening for Niemann-Pick disease type C in adults with neurological and psychiatric symptoms: findings from the ZOOM study.

Human molecular genetics
2013-11 | Journal article
DOI: 10.1093/hmg/ddt284
PMID: 23773996
PMC: PMC3792693
Contributors: Bauer P; Balding DJ; Klünemann HH; Linden DE; Ory DS; Pineda M; Priller J; Sedel F; Muller A; Chadha-Boreham H et al.
Source: Self-asserted source
Daniel Strasser via Europe PubMed Central

Examining the role of endogenous orexins in hypothalamus-pituitary-adrenal axis endocrine function using transient dual orexin receptor antagonism in the rat.

Psychoneuroendocrinology
2013-04 | Journal article
DOI: 10.1016/j.psyneuen.2012.07.016
PMID: 22917622
Contributors: Steiner MA; Sciarretta C; Brisbare-Roch C; Strasser DS; Studer R; Jenck F
Source: Self-asserted source
Daniel Strasser via Europe PubMed Central

Structure-guided design, synthesis and biological evaluation of novel DNA ligase inhibitors with in vitro and in vivo anti-staphylococcal activity.

Bioorganic & medicinal chemistry letters
2012-11 | Journal article
DOI: 10.1016/j.bmcl.2012.08.094
PMID: 23006603
Contributors: Surivet JP; Lange R; Hubschwerlen C; Keck W; Specklin JL; Ritz D; Bur D; Locher H; Seiler P; Strasser DS et al.
Source: Self-asserted source
Daniel Strasser via Europe PubMed Central

Vasopressin is involved in endothelin receptor antagonist-induced fluid retention in rat. Differential effect of selective ETA and dual ETA/ETB receptor antagonists

European Respiratory Society 2012
2012-09-04 | Conference poster
Source: Self-asserted source
Daniel Strasser

Identification of cathepsin L as a potential sex-specific biomarker for renal damage.

Hypertension (Dallas, Tex. : 1979)
2011-04 | Journal article
DOI: 10.1161/hypertensionaha.110.157206
PMID: 21357272
Contributors: Bauer Y; Hess P; Qiu C; Klenk A; Renault B; Wanner D; Studer R; Killer N; Stalder AK; Stritt M et al.
Source: Self-asserted source
Daniel Strasser via Europe PubMed Central

Differential effects of the dual orexin receptor antagonist almorexant and the GABA(A)-α1 receptor modulator zolpidem, alone or combined with ethanol, on motor performance in the rat.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
2011-03 | Journal article
DOI: 10.1038/npp.2010.224
PMID: 21150905
PMC: PMC3055732
Contributors: Steiner MA; Lecourt H; Strasser DS; Brisbare-Roch C; Jenck F
Source: Self-asserted source
Daniel Strasser via Europe PubMed Central

A fragment-based in situ combinatorial approach to identify high-affinity ligands for unknown binding sites.

Angewandte Chemie (International ed. in English)
2010-08 | Journal article
DOI: 10.1002/anie.200907254
PMID: 20818756
Contributors: Shelke SV; Cutting B; Jiang X; Koliwer-Brandl H; Strasser DS; Schwardt O; Kelm S; Ernst B
Source: Self-asserted source
Daniel Strasser via Europe PubMed Central

Kinetic and thermodynamic properties of MAG antagonists.

Carbohydrate research
2010-07 | Journal article
DOI: 10.1016/j.carres.2010.03.010
PMID: 20359700
Contributors: Mesch S; Lemme K; Koliwer-Brandl H; Strasser DS; Schwardt O; Kelm S; Ernst B
Source: Self-asserted source
Daniel Strasser via Europe PubMed Central

2-imino-thiazolidin-4-one derivatives as potent, orally active S1P1 receptor agonists.

Journal of medicinal chemistry
2010-05 | Journal article
DOI: 10.1021/jm100181s
PMID: 20446681
Contributors: Bolli MH; Abele S; Binkert C; Bravo R; Buchmann S; Bur D; Gatfield J; Hess P; Kohl C; Mangold C et al.
Source: Self-asserted source
Daniel Strasser via Europe PubMed Central

Low molecular weight antagonists of the myelin-associated glycoprotein: synthesis, docking, and biological evaluation.

Journal of medicinal chemistry
2010-02 | Journal article
DOI: 10.1021/jm901517k
PMID: 20095613
Contributors: Mesch S; Moser D; Strasser DS; Kelm A; Cutting B; Rossato G; Vedani A; Koliwer-Brandl H; Wittwer M; Rabbani S et al.
Source: Self-asserted source
Daniel Strasser via Europe PubMed Central

Comparative epitope mapping with saturation transfer difference NMR of sialyl Lewis(a) compounds and derivatives bound to a monoclonal antibody.

Journal of medicinal chemistry
2005-11 | Journal article
DOI: 10.1021/jm0502687
PMID: 16250646
Contributors: Herfurth L; Ernst B; Wagner B; Ricklin D; Strasser DS; Magnani JL; Benie AJ; Peters T
Source: Self-asserted source
Daniel Strasser via Europe PubMed Central
How many people are using ORCID?