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ResearcherID: K-7264-2016
Scopus Author ID: 35727101900

Keywords

cancer, stem cells, angiogenesis, intervertebral disc, microglia, neuroinflammation

Countries

Italy

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Employment (2)

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico: Milan, IT

2013-06-01 to present | Researcher (Surgery, Neurosurgery Unit)
Employment
Source: Self-asserted source
stefania elena navone

Fondazione IRCCS Istituto Neurologico Carlo Besta: Milano, Lombardia, IT

2006-12-12 to 2013-04-30 | researcher (Cerebrovascular Disease)
Employment
Source: Self-asserted source
stefania elena navone

Works (50 of 51)

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Role of Luteolin as Potential New Therapeutic Option for Patients with Glioblastoma through Regulation of Sphingolipid Rheostat

International Journal of Molecular Sciences
2023-12-21 | Journal article
DOI: 10.3390/ijms25010130
Contributors: Stefania Elena Navone; Laura Guarnaccia; Massimiliano D. Rizzaro; Laura Begani; Emanuela Barilla; Giovanni Alotta; Emanuele Garzia; Manuela Caroli; Antonella Ampollini; Aniello Violetti et al.
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A Targeted Next-Generation Sequencing Panel to Genotype Gliomas

Life
2022-06-24 | Journal article
DOI: 10.3390/life12070956
Contributors: Maria Guarnaccia; Laura Guarnaccia; Valentina La Cognata; Stefania Navone; Rolando Campanella; Antonella Ampollini; Marco Locatelli; Monica Miozzo; Giovanni Marfia; Sebastiano Cavallaro
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Effects of Metformin as Add-On Therapy against Glioblastoma: An Old Medicine for Novel Oncology Therapeutics

Cancers
2022-03-10 | Journal article
DOI: 10.3390/cancers14061412
Contributors: Laura Guarnaccia; Stefania E. Navone; Matteo M. Masseroli; Melissa Balsamo; Manuela Caroli; Silvia Valtorta; Rosa M. Moresco; Rolando Campanella; Luigi Schisano; Giorgio Fiore et al.
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Frontiers in Anti-Cancer Drug Discovery: Challenges and Perspectives of Metformin as Anti-Angiogenic Add-On Therapy in Glioblastoma

Cancers
2021-12-27 | Journal article
DOI: 10.3390/cancers14010112
Contributors: Laura Guarnaccia; Giovanni Marfia; Matteo Maria Masseroli; Stefania Elena Navone; Melissa Balsamo; Manuela Caroli; Silvia Valtorta; Rosa Maria Moresco; Rolando Campanella; Emanuele Garzia et al.
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Frontiers in Anti-cancer Drug Discovery: Challenges and Perspectives of Metformin as Anti-angiogenic Add-on Therapy in Glioblastoma

2021-11-29 | Preprint
DOI: 10.20944/preprints202111.0531.v1
Contributors: Laura Guarnaccia; Stefania Elena Navone; Matteo Maria Masseroli; Melissa Balsamo; Manuela Caroli; Silvia Valtorta; Rosa Maria Moresco; Rolando Campanella; Emanuele Garzia; Laura Riboni et al.
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Inflammatory interactions between degenerated intervertebral discs and microglia: Implication of sphingosine‐1‐phosphate signaling

Journal of Orthopaedic Research
2021-07 | Journal article
DOI: 10.1002/jor.24827
Contributors: Stefania E. Navone; Rolando Campanella; Laura Guarnaccia; Jean A. Ouellet; Marco Locatelli; Chiara Cordiglieri; Roberta Gualtierotti; Chiara Gaudino; Giuseppe Ciniglio Appiani; Sabino Luzzi et al.
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Decreased serum level of sphingosine-1-phosphate: a novel predictor of clinical severity in COVID-19.

EMBO molecular medicine
2020-11-14 | Journal article
DOI: 10.15252/emmm.202013424
PMID: 33190411
PMC: PMC7744841
Source: Self-asserted source
stefania elena navone

Personalized and translational approach for malignant brain tumors in the era of precision medicine: the strategic contribution of an experienced neurosurgery laboratory in a modern neurosurgery and neuro-oncology department.

Journal of the neurological sciences
2020-08-06 | Journal article
DOI: 10.1016/j.jns.2020.117083
PMID: 32784071
Source: Self-asserted source
stefania elena navone

Sphingosine-1-Phosphate in the Tumor Microenvironment: A Signaling Hub Regulating Cancer Hallmarks.

Cells
2020-02-01 | Journal article
DOI: 10.3390/cells9020337
PMID: 32024090
PMC: PMC7072483
Source: Self-asserted source
stefania elena navone

Tumor-Educated Platelets and Angiogenesis in Glioblastoma: Another Brick in the Wall for Novel Prognostic and Targetable Biomarkers, Changing the Vision from a Localized Tumor to a Systemic Pathology.

Cells
2020-01-25 | Journal article
DOI: 10.3390/cells9020294
PMID: 31991805
PMC: PMC7072723
Source: Self-asserted source
stefania elena navone

Correlation of Preoperative Von Willebrand Factor with Magnetic Resonance Imaging Perfusion and Permeability Parameters as Predictors of Prognosis in Glioblastoma

World neurosurgery
2019 | Journal article
DOI: 10.1016/j.wneu.2018.09.216
Source: Self-asserted source
stefania elena navone
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Anterolateral Approach for Retrostyloid Superior Parapharyngeal Space Schwannomas Involving the Jugular Foramen Area: A 20-Year Experience.

World neurosurgery
2019-09-11 | Journal article
DOI: 10.1016/j.wneu.2019.09.006
PMID: 31520759
Source: Self-asserted source
stefania elena navone

The Genetic Landscape of Human Glioblastoma and Matched Primary Cancer Stem Cells Reveals Intratumour Similarity and Intertumour Heterogeneity

Stem Cells International
2019-03-07 | Journal article
DOI: 10.1155/2019/2617030
Contributors: Chiara Pesenti; Stefania Elena Navone; Laura Guarnaccia; Andrea Terrasi; Jole Costanza; Rosamaria Silipigni; Silvana Guarneri; Nicola Fusco; Laura Fontana; Marco Locatelli et al.
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Significance and Prognostic Value of The Coagulation Profile in Patients with Glioblastoma: Implications for Personalized Therapy

World Neurosurgery
2019-01 | Journal article
DOI: 10.1016/j.wneu.2018.09.177
Contributors: Stefania Elena Navone; Laura Guarnaccia; Marco Locatelli; Paolo Rampini; Manuela Caroli; Nicla La Verde; Chiara Gaudino; Nora Bettinardi; Laura Riboni; Giovanni Marfia et al.
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A bidirectional crosstalk between glioblastoma and brain endothelial cells potentiates the angiogenic and proliferative signaling of sphingosine-1-phosphate in the glioblastoma microenvironment

Biochimica et biophysica acta. Molecular and cell biology of lipids
2018 | Journal article
DOI: 10.1016/j.bbalip.2018.07.009
Source: Self-asserted source
stefania elena navone
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Angiogenesis in human brain tumors: screening of drug response through a patient-specific cell platform for personalized therapy

Scientific reports
2018 | Journal article
DOI: 10.1038/s41598-018-27116-7
Source: Self-asserted source
stefania elena navone
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Aspirin Affects Tumor Angiogenesis and Sensitizes Human Glioblastoma Endothelial Cells to Temozolomide, Bevacizumab, and Sunitinib, Impairing Vascular Endothelial Growth Factor-Related Signaling

World neurosurgery
2018 | Journal article
DOI: 10.1016/j.wneu.2018.08.080
Source: Self-asserted source
stefania elena navone
grade
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Mechanical loading of intervertebral disc modulates microglia proliferation, activation, and chemotaxis

Osteoarthritis and cartilage
2018 | Journal article
DOI: 10.1016/j.joca.2018.04.013
Source: Self-asserted source
stefania elena navone
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Spontaneous intracerebral hemorrhage as presentation of atypical central neurocytoma: the role of angiogenesis through the characterization of tumor endothelial cells

Histology and histopathology
2018 | Journal article
DOI: 10.14670/hh-11-953
Source: Self-asserted source
stefania elena navone
grade
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Inflammatory mediators and signalling pathways controlling intervertebral disc degeneration

Histology and Histopathology
2017 | Journal article
DOI: 10.14670/HH-11-846
Source: Self-asserted source
stefania elena navone
grade
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Modulation of Neuroinflammation in the Central Nervous System: Role of Chemokines and Sphingolipids

Advances in Therapy
2017 | Journal article
DOI: 10.1007/s12325-016-0474-7
Source: Self-asserted source
stefania elena navone
grade
Preferred source (of 3)‎

Platelets from glioblastoma patients promote angiogenesis of tumor endothelial cells and exhibit increased VEGF content and release

Platelets
2017 | Journal article
DOI: 10.1080/09537104.2016.1247208
Source: Self-asserted source
stefania elena navone
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Increased VEGF levels in one case of papillary tumor of the pineal region with intracranial haemorrhage at presentation: a potential surrogate indicator of tumor angiogenesis and aggressiveness?

Journal of neurosurgical sciences
2016 | Journal article
Source: Self-asserted source
stefania elena navone

Platelet-derived sphingosine-1-phosphate and inflammation: from basic mechanisms to clinical implications

Platelets
2016 | Journal article
DOI: 10.3109/09537104.2016.1144179
EID:

2-s2.0-84961215971
Contributors: Vito, C.D.; Hadi, L.A.; Navone, S.E.; Marfia, G.; Campanella, R.; Mancuso, M.E.; Riboni, L.
Source: Self-asserted source
stefania elena navone via Scopus - Elsevier

Prognostic value of preoperative von Willebrand factor plasma levels in patients with Glioblastoma

Cancer Medicine
2016 | Journal article
DOI: 10.1002/cam4.747
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stefania elena navone
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The Adipose Mesenchymal Stem Cell Secretome Inhibits Inflammatory Responses of Microglia: Evidence for an Involvement of Sphingosine-1-Phosphate Signalling

Stem Cells and Development
2016 | Journal article
DOI: 10.1089/scd.2015.0268
EID:

2-s2.0-84978397825
Contributors: Marfia, G.; Navone, S.E.; Hadi, L.A.; Paroni, M.; Berno, V.; Beretta, M.; Gualtierotti, R.; Ingegnoli, F.; Levi, V.; Miozzo, M. et al.
Source: Self-asserted source
stefania elena navone via Scopus - Elsevier

Gene expression profile analysis of human mesenchymal stem cells from herniated and degenerated intervertebral discs reveals different expression of osteopontin

Stem Cells and Development
2015 | Journal article
DOI: 10.1089/scd.2014.0282
EID:

2-s2.0-84921453957
Contributors: Marfia, G.; Navone, S.E.; Di Vito, C.; Tabano, S.; Giammattei, L.; Di Cristofori, A.; Gualtierotti, R.; Tremolada, C.; Zavanone, M.; Caroli, M. et al.
Source: Self-asserted source
stefania elena navone via Scopus - Elsevier

Human CD14+ cells loaded with Paclitaxel inhibit in vitro cell proliferation of glioblastoma

Cytotherapy
2015 | Journal article
DOI: 10.1016/j.jcyt.2014.09.009
EID:

2-s2.0-84925119592
Contributors: Bonomi, A.; Lisini, D.; Navone, S.E.; Frigerio, S.; Dossena, M.; Ciusani, E.; Rampini, P.; Marfia, G.; Coccè, V.; Cavicchini, L. et al.
Source: Self-asserted source
stefania elena navone via Scopus - Elsevier

Isolation and expansion of brain microvascular endothelial cells

Handbook of Vascular Biology Techniques
2015 | Book
DOI: 10.1007/978-94-017-9716-0_18
Source: Self-asserted source
stefania elena navone
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Mesenchymal stem cells: Potential for therapy and treatment of chronic non-healing skin wounds

Organogenesis
2015 | Journal article
DOI: 10.1080/15476278.2015.1126018
EID:

2-s2.0-84964294549
Contributors: Marfia, G.; Navone, S.E.; Di Vito, C.; Ughi, N.; Tabano, S.; Miozzo, M.; Tremolada, C.; Bolla, G.; Crotti, C.; Ingegnoli, F. et al.
Source: Self-asserted source
stefania elena navone via Scopus - Elsevier

The role and function of sphingolipids in glioblastoma multiforme

Bioactive Sphingolipids in Cancer Biology and Therapy
2015 | Book
DOI: 10.1007/978-3-319-20750-6_12
Source: Self-asserted source
stefania elena navone
grade
Preferred source (of 2)‎

Autocrine/paracrine sphingosine-1-phosphate fuels proliferative and stemness qualities of glioblastoma stem cells

GLIA
2014 | Journal article
DOI: 10.1002/glia.22718
EID:

2-s2.0-84940261237
Contributors: Marfia, G.; Campanella, R.; Navone, S.E.; Di Vito, C.; Riccitelli, E.; Hadi, L.A.; Bornati, A.; de Rezende, G.; Giussani, P.; Tringali, C. et al.
Source: Self-asserted source
stefania elena navone via Scopus - Elsevier

Decellularized silk fibroin scaffold primed with adipose mesenchymal stromal cells improves wound healing in diabetic mice

Stem Cell Research and Therapy
2014 | Journal article
DOI: 10.1186/scrt396
EID:

2-s2.0-84892386657
Contributors: Navone, S.E.; Pascucci, L.; Dossena, M.; Ferri, A.; Invernici, G.; Acerbi, F.; Cristini, S.; Bedini, G.; Tosetti, V.; Ceserani, V. et al.
Source: Self-asserted source
stefania elena navone via Scopus - Elsevier

Human adipose-derived mesenchymal stem cells as a new model of spinal and bulbar muscular atrophy

PLoS ONE
2014 | Journal article
DOI: 10.1371/journal.pone.0112746
EID:

2-s2.0-84911472522
Contributors: Dossena, M.; Bedini, G.; Rusmini, P.; Giorgetti, E.; Canazza, A.; Tosetti, V.; Salsano, E.; Sagnelli, A.; Mariotti, C.; Gellera, C. et al.
Source: Self-asserted source
stefania elena navone via Scopus - Elsevier

Immortalization of human adipose-derived stromal cells: Production of cell lines with high growth rate, mesenchymal marker expression and capability to secrete high levels of angiogenic factors

Stem Cell Research and Therapy
2014 | Journal article
DOI: 10.1186/scrt452
EID:

2-s2.0-84901689224
Contributors: Balducci, L.; Blasi, A.; Saldarelli, M.; Soleti, A.; Pessina, A.; Bonomi, A.; Coccè, V.; Dossena, M.; Tosetti, V.; Ceserani, V. et al.
Source: Self-asserted source
stefania elena navone via Scopus - Elsevier

P17.15AUTOCRINE SPHINGOSINE-1-PHOSPHATE FUELS GROWTH AND STEMNESS IN GLIOBLASTOMA STEM CELLS

Neuro-oncology
2014 | Journal article
DOI: 10.1093/neuonc/nou174.345
Source: Self-asserted source
stefania elena navone

Potential use of human adipose mesenchymal stromal cells for intervertebral disc regeneration: A preliminary study on biglycan-deficient murine model of chronic disc degeneration

Arthritis Research and Therapy
2014 | Journal article
DOI: 10.1186/s13075-014-0457-5
Source: Self-asserted source
stefania elena navone
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Human and mouse brain-derived endothelial cells require high levels of growth factors medium for their isolation, in vitro maintenance and survival

Vascular Cell
2013 | Journal article
DOI: 10.1186/2045-824X-5-10
EID:

2-s2.0-84877612183
Contributors: Navone, S.E.; Marfia, G.; Nava, S.; Invernici, G.; Cristini, S.; Balbi, S.; Sangiorgi, S.; Ciusani, E.; Bosutti, A.; Alessandri, G. et al.
Source: Self-asserted source
stefania elena navone via Scopus - Elsevier

Human skin-derived fibroblasts acquire in vitro anti-tumor potential after priming with paclitaxel

Anti-Cancer Agents in Medicinal Chemistry
2013 | Journal article
DOI: 10.2174/1871520611313030015
EID:

2-s2.0-84876719039
Contributors: Pessina, A.; Coccè, V.; Bonomi, A.; Cavicchini, L.; Sisto, F.; Ferrari, M.; Ciusani, E.; Navone, S.; Marfia, G.; Parati, E. et al.
Source: Self-asserted source
stefania elena navone via Scopus - Elsevier

Isolation and expansion of human and mouse brain microvascular endothelial cells

Nature Protocols
2013 | Journal article
DOI: 10.1038/nprot.2013.107
EID:

2-s2.0-84883389240
Contributors: Navone, S.E.; Marfia, G.; Invernici, G.; Cristini, S.; Nava, S.; Balbi, S.; Sangiorgi, S.; Ciusani, E.; Bosutti, A.; Alessandri, G. et al.
Source: Self-asserted source
stefania elena navone via Scopus - Elsevier

Mesenchymal stromal cells primed with Paclitaxel attract and kill leukaemia cells, inhibit angiogenesis and improve survival of leukaemia-bearing mice

British Journal of Haematology
2013 | Journal article
DOI: 10.1111/bjh.12196
EID:

2-s2.0-84874684335
Contributors: Pessina, A.; Coccè, V.; Pascucci, L.; Bonomi, A.; Cavicchini, L.; Sisto, F.; Ferrari, M.; Ciusani, E.; Crovace, A.; Falchetti, M.L. et al.
Source: Self-asserted source
stefania elena navone via Scopus - Elsevier

Expression of neural and neurotrophic markers in nucleus pulposus cells isolated from degenerated intervertebral disc

Journal of Orthopaedic Research
2012 | Journal article
DOI: 10.1002/jor.22098
EID:

2-s2.0-84863854306
Contributors: Navone, S.E.; Marfia, G.; Canzi, L.; Ciusani, E.; Canazza, A.; Visintini, S.; Campanella, R.; Parati, E.A.
Source: Self-asserted source
stefania elena navone via Scopus - Elsevier

Human skeletal muscle stem cell antiinflammatory activity ameliorates clinical outcome in amyotrophic lateral sclerosis models.

Molecular medicine (Cambridge, Mass.)
2012 | Journal article
EID:

2-s2.0-84865639688
Contributors: Canzi, L.; Castellaneta, V.; Navone, S.; Nava, S.; Dossena, M.; Zucca, I.; Mennini, T.; Bigini, P.; Parati, E.A.
Source: Self-asserted source
stefania elena navone via Scopus - Elsevier

Transforming growth factor-beta1 induces microvascular abnormalities through a down-modulation of neural cell adhesion molecule in human hepatocellular carcinoma

Laboratory Investigation
2012 | Journal article
DOI: 10.1038/labinvest.2012.94
EID:

2-s2.0-84865635031
Contributors: Balzarini, P.; Benetti, A.; Invernici, G.; Cristini, S.; Zicari, S.; Caruso, A.; Gatta, L.B.; Berenzi, A.; Imberti, L.; Zanotti, C. et al.
Source: Self-asserted source
stefania elena navone via Scopus - Elsevier

An innovative treatment for cardiac failure: Autologous stem cell transplantation

Heart Transplantation: Indications and Contraindications, Procedures and Complications
2011 | Book
EID:

2-s2.0-84895366964
Contributors: Invernici, G.; Cristini, S.; Navone, S.; Canzi, L.; Parati, E.A.
Source: Self-asserted source
stefania elena navone via Scopus - Elsevier

Dermal fibroblasts display similar phenotypic and differentiation capacity to fat-derived mesenchymal stem cells, but differ in anti-inflammatory and angiogenic potential

Vascular Cell
2011 | Journal article
DOI: 10.1186/2045-824X-3-5
EID:

2-s2.0-79955595037
Contributors: Blasi, A.; Martino, C.; Balducci, L.; Saldarelli, M.; Soleti, A.; Navone, S.; Canzi, L.; Cristini, S.; Invernici, G.; Parati, E. et al.
Source: Self-asserted source
stefania elena navone via Scopus - Elsevier

Mesenchymal stromal cells primed with paclitaxel provide a new approach for cancer therapy

PLoS ONE
2011 | Journal article
DOI: 10.1371/journal.pone.0028321
EID:

2-s2.0-83755196419
Contributors: Pessina, A.; Bonomi, A.; Coccè, V.; Invernici, G.; Navone, S.; Cavicchini, L.; Sisto, F.; Ferrari, M.; Viganò, L.; Locatelli, A. et al.
Source: Self-asserted source
stefania elena navone via Scopus - Elsevier

Nanotechnology advances in brain tumors: The state of the art

Recent Patents on Anti-Cancer Drug Discovery
2011 | Journal article
DOI: 10.2174/157489211793979990
EID:

2-s2.0-78650959917
Contributors: Invernici, G.; Cristini, S.; Alessandri, G.; Navone, S.E.; Canzi, L.; Tavian, D.; Redaelli, C.; Acerbi, F.; Parati, E.A.
Source: Self-asserted source
stefania elena navone via Scopus - Elsevier

Human neural stem cells: A model system for the study of Lesch-Nyhan disease neurological aspects

Human Molecular Genetics
2010 | Journal article
DOI: 10.1093/hmg/ddq072
EID:

2-s2.0-77952487178
Contributors: Cristini, S.; Navone, S.; Canzi, L.; Acerbi, F.; Ciusani, E.; Hladnik, U.; de Gemmis, P.; Alessandri, G.; Colombo, A.; Parati, E. et al.
Source: Self-asserted source
stefania elena navone via Scopus - Elsevier

Stem cell patents: An innovative approach to anti-cancer drug discovery

Recent Patents on Anti-Cancer Drug Discovery
2010 | Journal article
DOI: 10.2174/157489210789702235
EID:

2-s2.0-77649250064
Contributors: Navone, S.; Cristini, S.; Canzi, L.; Parati, E.A.; Invernici, G.
Source: Self-asserted source
stefania elena navone via Scopus - Elsevier
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