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Works (13)

Development of New Resolvin D1 Analogues for Osteoarthritis Therapy: Acellular and Computational Approaches to Study Their Antioxidant Activities

Antioxidants
2024-03-22 | Journal article
Contributors: Zahra Kariminezhad; Mahdi Rahimi; Julio Fernandes; René Maltais; Jean-Yves Sancéau; Donald Poirier; Hassan Fahmi; Mohamed Benderdour
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A simple and convenient synthesis of labeled 9-hydroxy[ 13 C 6 ]phenanthrene as internal standard for mass spectrometry quantification of a key phenanthrene metabolite in human urines

Synthetic Communications
2024-02 | Journal article
Contributors: Jean-Yves Sancéau; Éric Gaudreau; René Maltais; Donald Poirier
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Aminosteroid RM-581 Decreases Cell Proliferation of All Breast Cancer Molecular Subtypes, Alone and in Combination with Breast Cancer Treatments

Journal of Clinical Medicine
2023-06-24 | Journal article
Contributors: Anna Burguin; Jenny Roy; Geneviève Ouellette; René Maltais; Juliette Bherer; Caroline Diorio; Donald Poirier; Francine Durocher
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A Concise, Gram-Scale Total Synthesis of Protectin DX and Related Labeled Versions via a Key Stereoselective Reduction of Enediyne

The Journal of Organic Chemistry
2023-06-02 | Journal article
Contributors: René Maltais; Jean-Yves Sancéau; Donald Poirier; André Marette
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An Aminosteroid Derivative Shows Higher In Vitro and In Vivo Potencies than Gold Standard Drugs in Androgen-Dependent Prostate Cancer Models

Cancers
2023-06-02 | Journal article
Contributors: Donald Poirier; Jenny Roy; René Maltais; Cindy Weidmann; Étienne Audet-Walsh
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Chemical Synthesis and Biological Evaluation of 3-Substituted Estrone/Estradiol Derivatives as 17β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors Acting via a Reverse Orientation of the Natural Substrate Estrone

Molecules
2023-01-07 | Journal article
Contributors: Adrien Djiemeny Ngueta; Jenny Roy; René Maltais; Donald Poirier
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An Improved Synthesis of Glucuronide Metabolites of Hindered Phenolic Xenoestrogens

Current Organic Synthesis
2022-11 | Journal article
Contributors: Jean-Yves Sancéau; Donald Poirier; Patrick Bélanger; René Maltais
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Induction of Endoplasmic Reticulum Stress-Mediated Apoptosis by Aminosteroid RM-581 Efficiently Blocks the Growth of PC-3 Cancer Cells and Tumors Resistant or Not to Docetaxel

International Journal of Molecular Sciences
2021-10-17 | Journal article
Contributors: René Maltais; Jenny Roy; Martin Perreault; Sachiko Sato; Julie-Christine Lévesque; Donald Poirier
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A Targeted-Covalent Inhibitor of 17β-HSD1 Blocks Two Estrogen-Biosynthesis Pathways: In Vitro (Metabolism) and In Vivo (Xenograft) Studies in T-47D Breast Cancer Models

Cancers
2021-04-13 | Journal article
Contributors: Donald Poirier; Jenny Roy; René Maltais
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Insight into the Mechanism of 17β-Hydroxysteroid Dehydrogenase Type 3 Inhibition by the Androsterone Derivative RM-532-105

Current Enzyme Inhibition
2020-11-04 | Journal article
Contributors: Preyesh Stephen; Jenny Roy; René Maltais; Donald Poirier
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Design and synthesis of dansyl-labeled inhibitors of steroid sulfatase for optical imaging

Bioorganic & Medicinal Chemistry
2020-04 | Journal article
Contributors: René Maltais; Adrien Ngueta Djiemeny; Jenny Roy; Xavier Barbeau; Jean-Philippe Lambert; Donald Poirier
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Minor chemical modifications of the aminosteroid derivative RM-581 lead to major impact on its anticancer activity, metabolic stability and aqueous solubility

European Journal of Medicinal Chemistry
2020-02 | Journal article
Contributors: René Maltais; Martin Perreault; Jenny Roy; Donald Poirier
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Total Synthesis of the Antidiabetic (Type 2) Lipid Mediator Protectin DX/PDX

The Journal of Organic Chemistry
2019-01-18 | Journal article
Contributors: Jean-Yves Sancéau; René Maltais; Donald Poirier; André Marette
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Peer review (2 reviews for 2 publications/grants)

Review activity for ACS medicinal chemistry letters. (1)
Review activity for Journal of medicinal chemistry. (1)