Personal information

developmental biology, stem cells and development, neural crest, neural progenitors, nervous system development, computational biology, systems biology, organogenesis, tissue engineering
United Kingdom

Activities

Employment (4)

Imperial College London: London, London, GB

Group Leader, Sir Henry Dale Fellow (Institute of Clinical Sciences)
Employment
Source: Self-asserted source
Vicki Metzis

The Francis Crick Institute: London, GB

2014-01-06 to present | Career Development Fellow (National Institute for Medical Research)
Employment
Source: Self-asserted source
Vicki Metzis

University of Queensland Institute for Molecular Bioscience: Brisbane, QLD, AU

2012-11 to 2013-10 | Postdoctoral Scientist (Molecular Genetics and Development)
Employment
Source: Self-asserted source
Vicki Metzis

University of Queensland Institute for Molecular Bioscience: Brisbane, QLD, AU

2006-01 to 2007-05 | Research Assistant
Employment
Source: Self-asserted source
Vicki Metzis

Education and qualifications (3)

University of Queensland Institute for Molecular Bioscience: Brisbane, QLD, AU

2008-03 to 2012-11 | Doctor of Philosophy (Developmental Biology) (Molecular Genetics and Development)
Education
Source: Self-asserted source
Vicki Metzis

University of Queensland Institute for Molecular Bioscience: Brisbane, QLD, AU

2005-02 to 2005-12 | Bachelor of Science Hons (Class I) (Molecular Genetics and Development)
Education
Source: Self-asserted source
Vicki Metzis

University of Queensland: Brisbane, QLD, AU

2002-03 to 2004-12 | Bachelor of Science (Genetics and Molecular Cell Biology)
Education
Source: Self-asserted source
Vicki Metzis

Funding (4)

Investigating the molecular basis of cellular diversity in the nervous system

2020 to present | Grant
Wellcome Trust (London, GB)
GRANT_NUMBER:

218536/Z/19/Z

Source: Self-asserted source
Vicki Metzis

Cell autonomous and non-cell autonomous roles mediated by Patched1 in facial development

2012-03 to 2012-03 | Award
Company of Biologists (Cambridge, GB)
Source: Self-asserted source
Vicki Metzis

Patched1 is essential for nasal pit invagination in mouse

2011-08 to 2011-08 | Award
Society for Developmental Biology (MD, MD, US)
Source: Self-asserted source
Vicki Metzis

Dissecting the role of Patched1 in craniofacial development

2008-03 to 2011-09 | Salary award
Department of Education and Training, Australian Government (Canberra, AU)
Source: Self-asserted source
Vicki Metzis

Works (19)

Sox2 levels regulate the chromatin occupancy of WNT mediators in epiblast progenitors responsible for vertebrate body formation.

Nature cell biology
2022-05 | Journal article
Contributors: Blassberg R; Patel H; Watson T; Gouti M; Metzis V; Delás MJ; Briscoe J
Source: Self-asserted source
Vicki Metzis via Europe PubMed Central

Heads or tails: Making the spinal cord

Developmental Biology
2022-03 | Journal article
Part of ISSN: 0012-1606
Source: Self-asserted source
Vicki Metzis

Building consensus in neuromesodermal research: Current advances and future biomedical perspectives

Current Opinion in Cell Biology
2021-12 | Journal article
Part of ISSN: 0955-0674
Source: Self-asserted source
Vicki Metzis

Precision of tissue patterning is controlled by dynamical properties of gene regulatory networks.

Development (Cambridge, England)
2021-02 | Journal article
Contributors: Exelby K; Herrera-Delgado E; Perez LG; Perez-Carrasco R; Sagner A; Metzis V; Sollich P; Briscoe J
Source: Self-asserted source
Vicki Metzis via Europe PubMed Central

Sox2 levels configure the WNT response of epiblast progenitors responsible for vertebrate body formation

[]
2020-12-30 | Preprint
Source: Self-asserted source
Vicki Metzis

Precision of Tissue Patterning is Controlled by Dynamical Properties of Gene Regulatory Networks

[]
2019-07-31 | Preprint
Source: Self-asserted source
Vicki Metzis

ERK1/2 signalling dynamics promote neural differentiation by regulating the polycomb repressive complex

[]
2019-03-22 | Preprint
Source: Self-asserted source
Vicki Metzis

Nervous System Regionalization Entails Axial Allocation before Neural Differentiation.

Cell
2018-10 | Journal article
Contributors: Metzis V; Steinhauser S; Pakanavicius E; Gouti M; Stamataki D; Ivanovitch K; Watson T; Rayon T; Mousavy Gharavy SN; Lovell-Badge R et al.
Source: Self-asserted source
Vicki Metzis via Europe PubMed Central

c-Maf controls immune responses by regulating disease-specific gene networks and repressing IL-2 in CD4+ T cells.

Nature immunology
2018-05 | Journal article
Contributors: Gabryšová L; Alvarez-Martinez M; Luisier R; Cox LS; Sodenkamp J; Hosking C; Pérez-Mazliah D; Whicher C; Kannan Y; Potempa K et al.
Source: Self-asserted source
Vicki Metzis via Europe PubMed Central

Regionalization of the nervous system requires axial allocation prior to neural lineage commitment

2017-12 | Other
OTHER-ID:

PPR23158

Contributors: Metzis V; Steinhauser S; Pakanavicius E; Gouti M; Stamataki D; Lovell-Badge R; Luscombe NM; Briscoe J
Source: Self-asserted source
Vicki Metzis via Europe PubMed Central

Mutations in DZIP1L, which encodes a ciliary-transition-zone protein, cause autosomal recessive polycystic kidney disease.

Nature genetics
2017-07 | Journal article
Source: Self-asserted source
Vicki Metzis via Europe PubMed Central

Unmasking the ciliopathies: craniofacial defects and the primary cilium.

2015 | Journal article
Contributors: Cortés CR; Metzis V; Wicking C
Source: Self-asserted source
Vicki Metzis via Europe PubMed Central

The route to spinal cord cell types: a tale of signals and switches.

2015-06 | Journal article
Contributors: Gouti M; Metzis V; Briscoe J
Source: Self-asserted source
Vicki Metzis via Europe PubMed Central

Patched1 is required in neural crest cells for the prevention of orofacial clefts.

2013-12 | Journal article
Contributors: Metzis V; Courtney AD; Kerr MC; Ferguson C; Rondón Galeano MC; Parton RG; Wainwright BJ; Wicking C
Source: Self-asserted source
Vicki Metzis via Europe PubMed Central

Inactivation of Patched1 in the mouse limb has novel inhibitory effects on the chondrogenic program.

2010-09 | Journal article
Contributors: Bruce SJ; Butterfield NC; Metzis V; Town L; McGlinn E; Wicking C
Source: Self-asserted source
Vicki Metzis via Europe PubMed Central

The metalloendopeptidase gene Pitrm1 is regulated by hedgehog signaling in the developing mouse limb and is expressed in muscle progenitors.

2009-12 | Journal article
Contributors: Town L; McGlinn E; Fiorenza S; Metzis V; Butterfield NC; Richman JM; Wicking C
Source: Self-asserted source
Vicki Metzis via Europe PubMed Central

Patched 1 is a crucial determinant of asymmetry and digit number in the vertebrate limb.

2009-10 | Journal article
Contributors: Butterfield NC; Metzis V; McGlinn E; Bruce SJ; Wainwright BJ; Wicking C
Source: Self-asserted source
Vicki Metzis via Europe PubMed Central

Expression of the NET family member Zfp503 is regulated by hedgehog and BMP signaling in the limb.

2008-04 | Journal article
Contributors: McGlinn E; Richman JM; Metzis V; Town L; Butterfield NC; Wainwright BJ; Wicking C
Source: Self-asserted source
Vicki Metzis via Europe PubMed Central

A dual enhancer-silencer element ensures transient Cdx2 expression during posterior body formation

Source: check_circle
EMBL-EBI

Peer review (4 reviews for 2 publications/grants)

Review activity for iScience. (1)
Review activity for Nature communications (3)