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Poland

Biography

I have devoted my professional career to developing proven research innovation as I am finding pleasure in discovery and observation.

I have background as an accomplished know-how scientist with years of experience delivering complex solutions for top organizations in the technology, healthcare, and pharmaceutical GMP quality assurance sectors as Charles River Ireland (Drug Validation and Development), Selvita Poland (Drug Development), National Institutes of Health, Bethesda USA (DNA Repair and Metabolism), A*STAR - Agency for Science, Technology and Research, Singapore and Children's Medical Research Institute, Australia (Gene Therapy AAV).

Activities

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Employment (1)

Institute of Pharmacology: Krakow, PL

2020-01-01 to present | Associate Professor (Department of Pharmacokinetics and Drug Metabolism)
Employment
Source: Self-asserted source
Wojciech Kuban

Works (14)

The Effect of Maternal High-Fat or High-Carbohydrate Diet during Pregnancy and Lactation on Cytochrome P450 2D (CYP2D) in the Liver and Brain of Rat Offspring

International Journal of Molecular Sciences
2024-07-19 | Journal article
DOI: 10.3390/ijms25147904
Contributors: Wojciech Kuban; Anna Haduch; Ewa Bromek; Agnieszka Basińska-Ziobroń; Kinga Gawlińska; Dawid Gawliński; Małgorzata Filip; Władysława A. Daniel
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Molecular Mechanisms of the Regulation of Liver Cytochrome P450 by Brain NMDA Receptors and via the Neuroendocrine Pathway—A Significance for New Psychotropic Therapies

International Journal of Molecular Sciences
2023-11-28 | Journal article
DOI: 10.3390/ijms242316840
Contributors: Renata Pukło; Ewa Bromek; Anna Haduch; Agnieszka Basińska-Ziobroń; Wojciech Kuban; Władysława A. Daniel
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The Engagement of Cytochrome P450 Enzymes in Tryptophan Metabolism

Metabolites
2023-05-05 | Journal article
DOI: 10.3390/metabo13050629
Contributors: Anna Haduch; Ewa Bromek; Wojciech Kuban; Władysława Anna Daniel
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The Effect of Chronic Iloperidone Treatment on Cytochrome P450 Expression and Activity in the Rat Liver: Involvement of Neuroendocrine Mechanisms

International Journal of Molecular Sciences
2021-08-06 | Journal article
DOI: 10.3390/ijms22168447
Contributors: Przemysław J. Danek; Wojciech Kuban; Władysława A. Daniel
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Cytochrome P450 expression and regulation in the brain.

Drug metabolism reviews
2020-12-27 | Journal article
DOI: 10.1080/03602532.2020.1858856
PMID: 33356626
Source: Self-asserted source
Wojciech Kuban
grade
Preferred source (of 2)‎

Replication fidelity in E. coli: Differential leading and lagging strand effects for dnaE antimutator alleles.

DNA repair
2019-07 | Journal article
DOI: 10.1016/j.dnarep.2019.102643
PMID: 31324532
PMC: PMC6801068
Contributors: Makiela-Dzbenska K; Maslowska KH; Kuban W; Gawel D; Jonczyk P; Schaaper RM; Fijalkowska IJ
Source: Self-asserted source
Wojciech Kuban via Europe PubMed Central

Removal of misincorporated ribonucleotides from prokaryotic genomes: an unexpected role for nucleotide excision repair.

PLoS genetics
2013-11 | Journal article
DOI: 10.1371/journal.pgen.1003878
PMID: 24244177
PMC: PMC3820734
Contributors: Vaisman A; McDonald JP; Huston D; Kuban W; Liu L; Van Houten B; Woodgate R
Source: Self-asserted source
Wojciech Kuban via Europe PubMed Central

Mechanisms employed by Escherichia coli to prevent ribonucleotide incorporation into genomic DNA by Pol V.

PLoS genetics
2012-11 | Journal article
DOI: 10.1371/journal.pgen.1003030
PMID: 23144626
PMC: PMC3493448
Contributors: McDonald JP; Vaisman A; Kuban W; Goodman MF; Woodgate R
Source: Self-asserted source
Wojciech Kuban via Europe PubMed Central

Escherichia coli UmuC active site mutants: effects on translesion DNA synthesis, mutagenesis and cell survival.

DNA repair
2012-07 | Journal article
DOI: 10.1016/j.dnarep.2012.06.005
PMID: 22784977
PMC: PMC3419331
Contributors: Kuban W; Vaisman A; McDonald JP; Karata K; Yang W; Goodman MF; Woodgate R
Source: Self-asserted source
Wojciech Kuban via Europe PubMed Central

Critical amino acids in Escherichia coli UmuC responsible for sugar discrimination and base-substitution fidelity.

Nucleic acids research
2012-03 | Journal article
DOI: 10.1093/nar/gks233
PMID: 22422840
PMC: PMC3401427
Contributors: Vaisman A; Kuban W; McDonald JP; Karata K; Yang W; Goodman MF; Woodgate R
Source: Self-asserted source
Wojciech Kuban via Europe PubMed Central

KIT codon 558 insertions in gastrointestinal stromal tumors. Analysis of 17 rare KIT mutants.

Human pathology
2008-08 | Journal article
DOI: 10.1016/j.humpath.2008.05.011
PMID: 18715619
Contributors: Lasota J; Kuban W; Wardelmann E; Debiec-Rychter M; Merkelbach-Bruse S; Sciot R; Rys J; Steigen SE; Iwanik K; Holden JA et al.
Source: Self-asserted source
Wojciech Kuban via Europe PubMed Central

Role of DNA polymerase IV in Escherichia coli SOS mutator activity.

Journal of bacteriology
2006-09 | Journal article
DOI: 10.1128/jb.01088-06
PMID: 16980447
PMC: PMC1636302
Contributors: Kuban W; Banach-Orlowska M; Schaaper RM; Jonczyk P; Fijalkowska IJ
Source: Self-asserted source
Wojciech Kuban via Europe PubMed Central

Mutator phenotype resulting from DNA polymerase IV overproduction in Escherichia coli: preferential mutagenesis on the lagging strand.

Journal of bacteriology
2005-10 | Journal article
DOI: 10.1128/jb.187.19.6862-6866.2005
PMID: 16166552
PMC: PMC1251572
Contributors: Kuban W; Banach-Orlowska M; Bialoskorska M; Lipowska A; Schaaper RM; Jonczyk P; Fijalkowska IJ
Source: Self-asserted source
Wojciech Kuban via Europe PubMed Central

Role of Escherichia coli DNA polymerase IV in in vivo replication fidelity.

Journal of bacteriology
2004-07 | Journal article
DOI: 10.1128/jb.186.14.4802-4807.2004
PMID: 15231812
PMC: PMC438567
Contributors: Kuban W; Jonczyk P; Gawel D; Malanowska K; Schaaper RM; Fijalkowska IJ
Source: Self-asserted source
Wojciech Kuban via Europe PubMed Central

Peer review (6 reviews for 2 publications/grants)

Review activity for Pharmacological Reports. (1)
Review activity for Pharmacological Reports. (5)
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