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Employment (2)

Howard Hughes Medical Institute: Chevy Chase, Maryland, US

2021-10-01 to present | Investigator
Employment
Source: Self-asserted source
Nels Elde

The University of Utah: Salt Lake City, UT, US

2011-07-01 to present | Professor (Human Genetics)
Employment
Source: Self-asserted source
Nels Elde

Works (24)

Hidden evolutionary constraints dictate the retention of coronavirus accessory genes

Current Biology
2024-12 | Journal article
Contributors: Stephen A. Goldstein; Teagan M. Feeley; Kristina M. Babler; Zoë A. Hilbert; Diane M. Downhour; Niema Moshiri; Nels C. Elde
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Crossref

Distinct routes to thermotolerance in the fungal pathogenCryptococcus neoformans

2024-04-09 | Preprint
Contributors: Mara J. W. Schwiesow; Nels C. Elde; Zoë A. Hilbert
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Crossref

Recurrent viral capture of cellular phosphodiesterases that antagonize OAS-RNase L

Proceedings of the National Academy of Sciences
2024-01-30 | Journal article
Contributors: Stephen A. Goldstein; Nels C. Elde
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Crossref

Distinct pathways of adaptive evolution in Cryptococcus neoformans reveal a mutation in adenylyl cyclase with trade-offs for pathogenicity

Current Biology
2023-10 | Journal article
Contributors: Zoë A. Hilbert; Joseph M. Bednarek; Mara J.W. Schwiesow; Krystal Y. Chung; Christian T. Moreau; Jessica C.S. Brown; Nels C. Elde
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Crossref

Hidden evolutionary constraints dictate the retention of coronavirus accessory genes

2023-10-14 | Preprint
Contributors: Stephen A. Goldstein; Teagan M. Feeley; Kristina M. Babler; Zoë A. Hilbert; Diane M. Downhour; Niema Moshiri; Nels C. Elde
Source: check_circle
Crossref

Structural homology screens reveal host-derived poxvirus protein families impacting inflammasome activity

Cell Reports
2023-08 | Journal article
Contributors: Ian N. Boys; Alex G. Johnson; Meghan R. Quinlan; Philip J. Kranzusch; Nels C. Elde
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Crossref

Microbe transmission from pet shop to lab-reared zebrafish reveals a pathogenic birnavirus

2023-08-28 | Preprint
Contributors: Marlen C. Rice; Nels C. Elde; James A. Gagnon; Keir M. Balla
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Crossref

Recurrent Viral Capture of Cellular Phosphodiesterases that Antagonize OAS-RNase L

2023-05-14 | Preprint
Contributors: Stephen A. Goldstein; Nels C. Elde
Source: check_circle
Crossref

Structural homology screens reveal poxvirus-encoded proteins impacting inflammasome-mediated defenses

2023-02-27 | Preprint
Contributors: Ian N. Boys; Alex G. Johnson; Meghan Quinlan; Philip J. Kranzusch; Nels C. Elde
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Crossref

Distinct pathways of adaptive evolution in Cryptococcus neoformans reveal a point mutation in adenylate cyclase with drastic tradeoffs for pathogenicity

2022-09-28 | Preprint
Contributors: Zoë A. Hilbert; Krystal Y. Chung; Joseph M. Bednarek; Mara W. Schwiesow; Jessica C.S. Brown; Nels C. Elde
Source: check_circle
Crossref

Poxviruses capture host genes by LINE-1 retrotransposition

eLife
2022-09-07 | Journal article
Contributors: Sarah M Fixsen; Kelsey R Cone; Stephen A Goldstein; Thomas A Sasani; Aaron R Quinlan; Stefan Rothenburg; Nels C Elde
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Crossref

Rapid Evolution of Glycan Recognition Receptors Reveals an Axis of Host-Microbe Conflicts at Carbohydrate-Protein Interfaces

2022-09-07 | Preprint
Contributors: Zoë A. Hilbert; Hannah J. Young; Mara Schwiesow; Nels C. Elde
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Crossref

Recurrent evolution of an inhibitor of ESCRT-dependent virus budding and LINE-1 retrotransposition in primates

Current Biology
2022-04 | Journal article
Contributors: Lara Rheinemann; Diane Miller Downhour; Kristen A. Davenport; Alesia N. McKeown; Wesley I. Sundquist; Nels C. Elde
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Crossref

Recurrent Emergence of an Antiviral Defense through Repeated Retrotransposition and Truncation of CHMP3

2021-04-27 | Preprint
Contributors: Lara Rheinemann; Diane Miller Downhour; Kristen A. Davenport; Alesia N. McKeown; Wesley I. Sundquist; Nels C. Elde
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Crossref

Extensive recombination-driven coronavirus diversification expands the pool of potential pandemic pathogens

2021-02-04 | Preprint
Contributors: Stephen A. Goldstein; Joe Brown; Brent S. Pedersen; Aaron R. Quinlan; Nels C. Elde
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Crossref

Signatures of host–pathogen evolutionary conflict reveal MISTR—A conserved MItochondrial STress Response network

PLOS Biology
2020-12-28 | Journal article
Contributors: Mahsa Sorouri; Mark L Siegal; Tyron Chang; Palmy Jesudhasan; Chelsea Pinkham; Nels C. Elde; Dustin C. Hancks
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Crossref

Poxviruses capture host genes by LINE-1 retrotransposition

2020-10-27 | Preprint
Contributors: Sarah M. Fixsen; Kelsey R. Cone; Stephen A. Goldstein; Thomas A. Sasani; Aaron R. Quinlan; Stefan Rothenburg; Nels C. Elde
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Crossref

Conflicts with diarrheal pathogens trigger rapid evolution of an intestinal signaling axis

2020-03-30 | Preprint
Contributors: Clayton M. Carey; Sarah E. Apple; Zoё A. Hilbert; Michael S. Kay; Nels C. Elde
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Crossref

Exploiting species specificity to understand the tropism of a human-specific toxin

Science Advances
2020-03-13 | Journal article
Contributors: K. M. Boguslawski; A. N. McKeown; C. J. Day; K. A. Lacey; K. Tam; N. Vozhilla; S. Y. Kim; M. P. Jennings; S. B. Koralov; N. C. Elde et al.
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Crossref

MISTR: A conserved MItochondrial STress Response network revealed by signatures of evolutionary conflict

2020-01-26 | Preprint
Contributors: Mahsa Sorouri; Tyron Chang; Palmy Jesudhasan; Chelsea Pinkham; Nels C. Elde; Dustin C. Hancks
Source: check_circle
Crossref

Discovery of a prevalent picornavirus by visualizing zebrafish immune responses

2019-10-30 | Other
Contributors: Keir M. Balla; Marlen C. Rice; James A. Gagnon; Nels C. Elde
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Crossref

Long read sequencing reveals poxvirus evolution through rapid homogenization of gene arrays

eLife
2018-08-29 | Journal article
Contributors: Thomas A Sasani; Kelsey R Cone; Aaron R Quinlan; Nels C Elde
Source: check_circle
Crossref

Recurrent loss-of-function mutations reveal costs to OAS1 antiviral activity in primates

2018-05-18 | Other
Contributors: Clayton M. Carey; Apurva Govande; Juliane M. Cooper; Melissa K. Hartley; Philip J. Kranzusch; Nels C. Elde
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Crossref

Long read sequencing reveals Poxvirus evolution through rapid homogenization of gene arrays

2018-01-09 | Other
Contributors: Thomas A. Sasani; Kelsey R. Cone; Aaron R. Quinlan; Nels C. Elde
Source: check_circle
Crossref

Peer review (3 reviews for 3 publications/grants)

Review activity for Current biology. (1)
Review activity for Nature microbiology. (1)
Review activity for PLOS pathogens : (1)