Personal information

Organic chemistry
Ireland

Biography

We're engaged in the development of efficient ways to prepare natural products (and their analogues) and with collaborators we aim to evaluating their biological activities.

Activities

Employment (1)

University College Dublin: Dublin, IE

2006-01-01 to present | Lecturer (School of Chemistry and Chemical Biology)
Employment
Source: Self-asserted source
Paul Evans

Education and qualifications (2)

University of York: York, York, GB

1994-10-01 to 1998-07-31 | DPhil (Chemistry)
Education
Source: Self-asserted source
Paul Evans

University of East Anglia: Norwich, Norfolk, GB

1990-10-01 to 1994-07-31 | BSc (Chemistry)
Education
Source: Self-asserted source
Paul Evans

Works (50 of 81)

Items per page:
Page 1 of 2

Synthesis of the cis‐ and trans‐3‐Fluoro Analogues of Febrifugine and Halofuginone

European Journal of Organic Chemistry
2025-02-03 | Journal article
Contributors: Fahad Alkhathami; Lee Yang Chieng; Yannick Ortin; Marina Rubini; Paul Evans
Source: check_circle
Crossref

Biosynthesis of a new skyllamycin in Streptomyces nodosus: a cytochrome P450 forms an epoxide in the cinnamoyl chain

Organic & Biomolecular Chemistry
2024 | Journal article
Contributors: Yuhao Song; Jose A. Amaya; Vidhi C. Murarka; Hugo Mendez; Mark Hogan; Jimmy Muldoon; Paul Evans; Yannick Ortin; Steven L. Kelly; David C. Lamb et al.
Source: check_circle
Crossref

4‐Aza Cyclopentenone Prostaglandin Analogues: Synthesis and NF‐κB Inhibitory Activities

ChemMedChem
2024-12-20 | Journal article
Contributors: William Doherty; Lorna Conway; Brian Leveau; Francesca Giulia Nacca; Lucia Chiappa; Anna Riccio; Stanley M. Roberts; M. Gabriella Santoro; Paul Evans
Source: check_circle
Crossref

A new route to the crinane skeleton via the low-valent titanium-mediated double reduction of cyclic sulfonamides

Tetrahedron Letters
2024-10 | Journal article
Contributors: Robert Redmond; Clara Dornan; Julia Bruno-Colmenarez; Paul Evans
Source: check_circle
Crossref

An Intramolecular Enyne Metathesis Approach for the Synthesis of Cyclic 3‐Substituted Unsaturated Sulfones

European Journal of Organic Chemistry
2023-12-06 | Journal article
Contributors: Dandan Lin; Anna Sullivan; Martha Cîrceie; Vittoria Chiericoni; Jaroslav Karpov; Kacper Kluza; Niamh O'Neill; Wilhelm Risse; Paul Evans
Source: check_circle
Crossref

Reduction of Substituted Benzo-Fused Cyclic Sulfonamides with Mg-MeOH: An Experimental and Computational Study

The Journal of Organic Chemistry
2022-09-16 | Journal article
Contributors: Aisha Khalifa; Robert Redmond; Goar Sánchez-Sanz; Paul Evans
Source: check_circle
Crossref

An enantiodivergent synthesis of N-Boc-protected (R)- and (S)-4-amino cyclopent-2-en-1-one

Journal of Chemical Research
2022-01 | Journal article
Contributors: Lorna Conway; Paul Evans
Source: check_circle
Crossref

Stereoselective synthesis of analogues of deoxyfebrifugine

Journal of Chemical Research
2022-01 | Journal article
Contributors: Raed K Zaidan; Paul Evans
Source: check_circle
Crossref

Cover Feature: Isomerisation of Vinyl Sulfones for the Stereoselective Synthesis of Vinyl Azides (Eur. J. Org. Chem. 43/2020)

European Journal of Organic Chemistry
2020-11-22 | Journal article
Contributors: Niall Collins; Robert Connon; Goar Sánchez‐Sanz; Paul Evans
Source: check_circle
Crossref

Isomerisation of Vinyl Sulfones for the Stereoselective Synthesis of Vinyl Azides

European Journal of Organic Chemistry
2020-10-22 | Journal article
Contributors: Niall Collins; Robert Connon; Goar Sánchez‐Sanz; Paul Evans
Source: check_circle
Crossref

Synthesis and Structural Elucidation of 1,2‐Disubstituted 3‐Fluoropiperidines

European Journal of Organic Chemistry
2020-03-08 | Journal article
Contributors: Pauline Fischer; Morgan Morris; Helge Müller‐Bunz; Paul Evans
Source: check_circle
Crossref

Strategies for the Asymmetric Construction of Pelletierine and its Use in the Synthesis of Sedridine, Myrtine, and Lasubine

European Journal of Organic Chemistry
2019-09 | Journal article
Contributors: Raed K. Zaidan; Paul Evans
Source: check_circle
Crossref

The Titanium-Mediated Double Reductive Cleavage of Cyclic Sulfonamides for the Synthesis of Aryl Pyrrolidines

The Journal of Organic Chemistry
2019-03-01 | Journal article
Contributors: Aisha Khalifa; Paul Evans
Source: check_circle
Crossref

Asymmetric synthesis of (-)- and (+)-neodichroine/hydrachine A from (+)- and (-)-febrifugine

Tetrahedron Letters
2018 | Journal article
WOSUID:

WOS:000430524700005

Contributors: Smullen, Shaun; Evans, Paul
Source: Self-asserted source
Paul Evans via ResearcherID

Chemical synthesis of febrifugine and analogues

Bioorganic & Medicinal Chemistry
2018 | Journal article
WOSUID:

WOS:000432473100001

Contributors: Smullen, Shaun; McLaughlin, Noel P.; Evans, Paul
Source: Self-asserted source
Paul Evans via ResearcherID

Ammonium formate-based one-pot reductive Heck reactions for the construction of cyclic sulfonamides

Tetrahedron Letters
2017 | Journal article
WOSUID:

WOS:000416191400017

Contributors: Khalifa, Aisha; Conway, Lorna; Geoghegan, Kimberly; Evans, Paul
Source: Self-asserted source
Paul Evans via ResearcherID

Evaluating the Antibacterial Properties of Polyacetylene and Glucosinolate Compounds with Further Identification of Their Presence within Various Carrot (Daucus carota) and Broccoli (Brassica oleracea) Cultivars Using High-Performance Liquid Chromatography with a Diode Array Detector and Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry Analyses

Journal of Agricultural and Food Chemistry
2017 | Journal article
WOSUID:

WOS:000408520200018

Contributors: Hinds, L.; Kenny, O.; Hossain, M. B.; Walsh, D.; Sheehy, E.; Evans, P.; Gaffney, M.; Rai, D. K.
Source: Self-asserted source
Paul Evans via ResearcherID

An asymmetric synthesis of febrifugine, halofuginone and their hemiketal isomers

Tetrahedron
2017-09 | Journal article
Contributors: Shaun Smullen; Paul Evans
Source: check_circle
Crossref

Alkynyldicobalt Derivatives of Dibenzosuberenol and Dibenzocyclooctatrien‐5‐ol: Ring Conformations, Ease of Carbonyl Elimination and Relevance to Pauson–Khand Cyclization

European Journal of Inorganic Chemistry
2017-04-03 | Journal article
Contributors: Sarah A. Brusey; Wen Shen; Helge Müller‐Bunz; Yannick Ortin; Paul Evans; Michael J. McGlinchey
Source: check_circle
Crossref

Synthesis and Evaluation of 1,2,3‐Triazole‐Containing Vinyl and Allyl Sulfones as Anti‐Trypanosomal Agents

European Journal of Organic Chemistry
2017-01-03 | Journal article
Contributors: William Doherty; Nikoletta Adler; Andrew Knox; Derek Nolan; Joanna McGouran; Anna Pratima Nikalje; Deepak Lokwani; Aniket Sarkate; Paul Evans
Source: check_circle
Crossref

15-Deoxy-Delta(12,14)-Prostaglandin J(2) Modifies components of the Proteasome and inhibits inflammatory responses in human endothelial cells

Frontiers in Immunology
2016 | Journal article
WOSUID:

WOS:000386389300001

Contributors: Marcone, Simone; Evans, Paul; Fitzgerald, Desmond J.
Source: Self-asserted source
Paul Evans via ResearcherID

A ring closing metathesis-manganese dioxide oxidation sequence for the synthesis of substituted pyrroles

Tetrahedron
2016 | Journal article
WOSUID:

WOS:000375336500004

Contributors: Keeley, Aaron; McCauley, Shane; Evans, Paul
Source: Self-asserted source
Paul Evans via ResearcherID

Aminooxylation Horner-Wadsworth-Emmons Sequence for the Synthesis of Enantioenriched gamma-Functionalized Vinyl Sulfones

Journal of Organic Chemistry
2016 | Journal article
WOSUID:

WOS:000370768000010

Contributors: Doherty, William; Evans, Paul
Source: Self-asserted source
Paul Evans via ResearcherID

Asymmetric synthesis of (+)- and (-)-deoxyfebrifugine and deoxyhalofuginone

Tetrahedron Letters
2015 | Journal article
WOSUID:

WOS:000364436300032

Contributors: Zaidan, Raed K.; Smullen, Shaun; Evans, Paul
Source: Self-asserted source
Paul Evans via ResearcherID

Quantifying tetrahedral adduct formation and stabilization in the cysteine and the serine proteases

Biochimica Et Biophysica Acta-Proteins and Proteomics
2015 | Journal article
WOSUID:

WOS:000362307500016

Contributors: Cleary, Jennifer A.; Doherty, William; Evans, Paul; Malthouse, J. Paul G.
Source: Self-asserted source
Paul Evans via ResearcherID

Quantitative human exposure model to assess the level of glucosinolates upon thermal processing of cruciferous vegetables

Lwt-Food Science and Technology
2015 | Journal article
WOSUID:

WOS:000355027600036

Contributors: Tiwari, Uma; Sheehy, Eimile; Rai, Dilip; Gaffney, Michael; Evans, Paul; Cummins, Enda
Source: Self-asserted source
Paul Evans via ResearcherID

Bis{2- (3,5-diphenyl-1H-pyrrol-2-ylidene-kappa N)amino -3,5-diphenylpyrrol-1-ido-kappa N}palladium(II): a homoleptic four-coordinate tetraphenylazadipyrromethene complex of palladium

Acta Crystallographica Section C-Structural Chemistry
2014 | Journal article
WOSUID:

WOS:000332218000010

Contributors: Jones, Roderick C.; Mueller-Bunz, Helge; Evans, Paul; O'Shea, Donal F.
Source: Self-asserted source
Paul Evans via ResearcherID

Hemiacetal stabilization in a chymotrypsin inhibitor complex and the reactivity of the hydroxyl group of the catalytic serine residue of chymotrypsin

Biochimica Et Biophysica Acta-Proteins and Proteomics
2014 | Journal article
WOSUID:

WOS:000336113900008

Contributors: Cleary, Jennifer A.; Doherty, William; Evans, Paul; Malthouse, J. Paul G.
Source: Self-asserted source
Paul Evans via ResearcherID

Preparation, anti-trypanosomal activity and localisation of a series of dipeptide-based vinyl sulfones

Organic & Biomolecular Chemistry
2014 | Journal article
WOSUID:

WOS:000342076100017

Contributors: Doherty, William; James, Jinju; Evans, Paul; Martin, Laura; Adler, Nikoletta; Nolan, Derek; Knox, Andrew
Source: Self-asserted source
Paul Evans via ResearcherID

Synthesis of (+)-perillyl alcohol from (+)-limonene

Tetrahedron Letters
2014 | Journal article
WOSUID:

WOS:000332432300010

Contributors: Geoghegan, Kimberly; Evans, Paul
Source: Self-asserted source
Paul Evans via ResearcherID

The chemistry and biology of febrifugine and halofuginone

Bioorganic & Medicinal Chemistry
2014 | Journal article
WOSUID:

WOS:000334337800002

Contributors: McLaughlin, Noel P.; Evans, Paul; Pines, Mark
Source: Self-asserted source
Paul Evans via ResearcherID

Absolute Configuration of Falcarinol (9Z-heptadeca-1,9-diene-4,6-diyn-3-ol) from Pastinaca sativa

Natural Product Communications
2013 | Journal article
WOSUID:

WOS:000323687500023

Contributors: Corell, Mireia; Sheehy, Emile; Evans, Paul; Brunton, Nigel; Valverde, Juan
Source: Self-asserted source
Paul Evans via ResearcherID

Double Reduction of Cyclic Aromatic Sulfonamides: Synthesis of (+)-Mesembrine and (+)-Mesembranol

Journal of Organic Chemistry
2013 | Journal article
WOSUID:

WOS:000317327800067

Contributors: Geoghegan, Kimberly; Evans, Paul
Source: Self-asserted source
Paul Evans via ResearcherID

Halonium Ion Triggered Rearrangement of Unsaturated Benzo-Annulated Bi- and Tricyclic Sulfonamides

Journal of Organic Chemistry
2013 | Journal article
WOSUID:

WOS:000326122200040

Contributors: Geoghegan, Kimberly; Smullen, Shaun; Evans, Paul
Source: Self-asserted source
Paul Evans via ResearcherID

Synthesis and immunostimulatory activity of two alpha-S-galactosyl phenyl-capped ceramides

Arkivoc
2013 | Journal article
WOSUID:

WOS:000324460900024

Contributors: Murphy, Niamh; Petrasca, Andreea; Murphy, Niamh M.; Reilly, Vincent O.; Evans, Paul; Doherty, Derek G.; Zhu, Xiangming
Source: Self-asserted source
Paul Evans via ResearcherID

trans-Tetradec-2-enoic Acid in Impatiens glandulifera

Synthetic Communications
2013 | Journal article
WOSUID:

WOS:000316063200009

Contributors: Ortin, Yannick; Evans, Paul
Source: Self-asserted source
Paul Evans via ResearcherID

Vinyl Sulfone-Based Peptidomimetics as Anti-Trypanosomal Agents: Design, Synthesis, Biological and Computational Evaluation

Journal of Medicinal Chemistry
2013 | Journal article
WOSUID:

WOS:000330097400010

Contributors: Dunny, Elizabeth; Doherty, William; Evans, Paul; Malthouse, J. Paul G.; Nolan, Derek; Knox, Andrew J. S.
Source: Self-asserted source
Paul Evans via ResearcherID

Regioselectivity in the Intramolecular Heck Reaction of a Series of Cyclic Sulfonamides: An Experimental and Computational Study

Chemistry-a European Journal
2012 | Journal article
WOSUID:

WOS:000309597000021

Contributors: Geoghegan, Kimberly; Evans, Paul; Rozas, Isabel; Alkorta, Ibon
Source: Self-asserted source
Paul Evans via ResearcherID

Temporary thio-derivatization in the synthesis of (+)-4-acetylbromoxone

Tetrahedron Letters
2012 | Journal article
WOSUID:

WOS:000310170300031

Contributors: O'Byrne, Aisling; O'Reilly, Steven; Tighe, Catherine; Evans, Paul; Ciuffini, Laura; Santoro, M. Gabriella
Source: Self-asserted source
Paul Evans via ResearcherID

An Investigation into the One-Pot Heck Olefination-Hydrogenation Reaction

Journal of Organic Chemistry
2011 | Journal article
WOSUID:

WOS:000288692000023

Contributors: Geoghegan, Kimberly; Kelleher, Susan; Evans, Paul
Source: Self-asserted source
Paul Evans via ResearcherID

Stereo-Inversion in the (4R)-gamma-Decanolactone Synthesis by Saccharomyces cerevisiae: (2E,4S)-4-Hydroxydec-2-enoic Acid Acts as a Key Intermediate

Helvetica Chimica Acta
2011 | Journal article
WOSUID:

WOS:000297800000002

Contributors: Koehler, Gunnar; Evans, Paul; Garbe, Leif-Alexander
Source: Self-asserted source
Paul Evans via ResearcherID

A short synthesis of (+) and (-)-falcarinol

Tetrahedron
2010 | Journal article
WOSUID:

WOS:000285432900007

Contributors: McLaughlin, Noel P.; Butler, Eibhlin; Evans, Paul; Brunton, Nigel P.; Koidis, Anastasios; Rai, Dilip K.
Source: Self-asserted source
Paul Evans via ResearcherID

Dihydroxylation of Vinyl Sulfones: Stereoselective Synthesis of (+)- and (-)-Febrifugine and Halofuginone

Journal of Organic Chemistry
2010 | Journal article
WOSUID:

WOS:000273400300037

Contributors: McLaughlin, Noel P.; Evans, Paul
Source: Self-asserted source
Paul Evans via ResearcherID

Selective generation of quaternary all-carbon-centres through Heck-cyclisations: synthesis of mesembrane

Chemical Communications
2010 | Journal article
WOSUID:

WOS:000274070800027

Contributors: Klein, Johannes E. M. N.; Geoghegan, Kimberly; Meral, Nicolas; Evans, Paul
Source: Self-asserted source
Paul Evans via ResearcherID

Stereocontrolled Synthesis of the PPAR-gamma Agonist 10-Nitrolinoleic Acid

Journal of Organic Chemistry
2010 | Journal article
WOSUID:

WOS:000280398100055

Contributors: Dunny, Elizabeth; Evans, Paul
Source: Self-asserted source
Paul Evans via ResearcherID

The thio-adduct facilitated, enzymatic kinetic resolution of 4-hydroxycyclopentenone and 4-hydroxycyclohexenone

Organic & Biomolecular Chemistry
2010 | Journal article
WOSUID:

WOS:000273745100008

Contributors: O'Byrne, Aisling; Murray, Cian; Keegan, Dearbhla; Palacio, Carole; Evans, Paul; Morgan, Ben S.
Source: Self-asserted source
Paul Evans via ResearcherID

Diastereoselective functionalisation of benzo-annulated bicyclic sultams: Application for the synthesis of cis-2,4-diarylpyrrolidines

Beilstein Journal of Organic Chemistry
2009 | Journal article
WOSUID:

WOS:000273529500001

Contributors: Kelleher, Susan; Quesne, Pierre-Yves; Evans, Paul
Source: Self-asserted source
Paul Evans via ResearcherID

Stereocontrolled preparation of bicyclic alkaloid analogues: an approach towards the kinabalurine skeleton

Tetrahedron
2009 | Journal article
WOSUID:

WOS:000270121400026

Contributors: Evans, Paul; Kavanagh, Yvonne; O'Brien, Matthew
Source: Self-asserted source
Paul Evans via ResearcherID

Studies concerning the electrophilic amino-alkene cyclisation for the synthesis of bicyclic amines

Organic & Biomolecular Chemistry
2009 | Journal article
WOSUID:

WOS:000263467700021

Contributors: Klein, Johannes E. M. N.; Mueller-Bunz, Helge; Evans, Paul
Source: Self-asserted source
Paul Evans via ResearcherID

X-ray Crystallographic and NMR Spectroscopic Study of (eta(2)-Alkene)(mu-alkyne)pentacarbonyldicobalt Complexes: Arrested Pauson-Khand Reaction Intermediates

Organometallics
2009 | Journal article
WOSUID:

WOS:000271200300023

Contributors: Brusey, Sarah A.; Banide, Emilie V.; Doerrich, Steffen; O'Donohue, Paul; Ortin, Yannick; Mueller-Bunz, Helge; Long, Conor; Evans, Paul; McGlinchey, Michael J.
Source: Self-asserted source
Paul Evans via ResearcherID
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Peer review (29 reviews for 6 publications/grants)

Review activity for ACS omega. (1)
Review activity for Chemistry - an Asian journal. (1)
Review activity for Journal of medicinal chemistry. (2)
Review activity for Journal of organic chemistry. (18)
Review activity for Organic letters. (5)
Review activity for Tetrahedron letters. (2)