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University of Oxford: Oxford, GB

PI (Wellcome Centre for Human Genetics)
Employment
Source: Self-asserted source
Anjali Hinch

Works (15)

Meiotic DNA breaks drive multifaceted mutagenesis in the human germ line

Science
2023-12 | Journal article
DOI: 10.1126/science.adh2531
Contributors: Robert Hinch; Peter Donnelly; Anjali Gupta Hinch
Source: check_circle
Crossref

Characterization of meiotic recombination intermediates through gene knockouts in founder hybrid mice

Genome Research
2023-11 | Journal article
DOI: 10.1101/gr.278024.123
Contributors: Benjamin Davies; Gang Zhang; Daniela Moralli; Samy Alghadban; Daniel Biggs; Chris Preece; Peter Donnelly; Anjali Gupta Hinch
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Crossref

Altering the Binding Properties of PRDM9 Partially Restores Fertility across the Species Boundary.

Molecular biology and evolution
2021-12 | Journal article
DOI: 10.1093/molbev/msab269
PMID: 34491357
PMC: PMC8662609
Contributors: Davies B; Gupta Hinch A; Cebrian-Serrano A; Alghadban S; Becker PW; Biggs D; Hernandez-Pliego P; Preece C; Moralli D; Zhang G et al.
Source: Self-asserted source
Anjali Hinch via Europe PubMed Central

Applications of Single-Cell DNA Sequencing.

Annual review of genomics and human genetics
2021-03 | Journal article
DOI: 10.1146/annurev-genom-111320-090436
PMID: 33722077
PMC: PMC8410678
Contributors: Evrony GD; Hinch AG; Luo C
Source: Self-asserted source
Anjali Hinch via Europe PubMed Central

ZCWPW1 is recruited to recombination hotspots by PRDM9 and is essential for meiotic double strand break repair.

eLife
2020-08 | Journal article
DOI: 10.7554/elife.53392
PMID: 32744506
PMC: PMC7494361
Contributors: Wells D; Bitoun E; Moralli D; Zhang G; Hinch A; Jankowska J; Donnelly P; Green C; Myers SR
Source: Self-asserted source
Anjali Hinch via Europe PubMed Central

The Configuration of RPA, RAD51, and DMC1 Binding in Meiosis Reveals the Nature of Critical Recombination Intermediates.

Molecular cell
2020-06 | Journal article
DOI: 10.1016/j.molcel.2020.06.015
PMID: 32610038
PMC: PMC7447979
Contributors: Hinch AG; Becker PW; Li T; Moralli D; Zhang G; Bycroft C; Green C; Keeney S; Shi Q; Davies B et al.
Source: Self-asserted source
Anjali Hinch via Europe PubMed Central

Molecular structures and mechanisms of DNA break processing in mouse meiosis.

Genes & development
2020-04 | Journal article
DOI: 10.1101/gad.336032.119
PMID: 32354835
PMC: PMC7263140
Contributors: Yamada S; Hinch AG; Kamido H; Zhang Y; Edelmann W; Keeney S
Source: Self-asserted source
Anjali Hinch via Europe PubMed Central

Molecular structures and mechanisms of DNA break processing in mouse meiosis

2019-12-17 | Preprint
DOI: 10.1101/2019.12.17.876854
Contributors: Shintaro Yamada; Anjali Gupta Hinch; Hisashi Kamido; Yongwei Zhang; Winfried Edelmann; Scott Keeney
Source: check_circle
Crossref

ZCWPW1 is recruited to recombination hotspots by PRDM9, and is essential for meiotic double strand break repair

2019-10-30 | Other
DOI: 10.1101/821678
Contributors: Daniel Wells; Emmanuelle Bitoun; Daniela Moralli; Gang Zhang; Anjali Gupta Hinch; Peter Donnelly; Catherine Green; Simon R Myers
Source: check_circle
Crossref

Factors influencing meiotic recombination revealed by whole-genome sequencing of single sperm

Science
2019-03-22 | Journal article
DOI: 10.1126/science.aau8861
Contributors: Anjali Gupta Hinch; Gang Zhang; Philipp W. Becker; Daniela Moralli; Robert Hinch; Benjamin Davies; Rory Bowden; Peter Donnelly
Source: check_circle
Crossref

Re-engineering the zinc fingers of PRDM9 reverses hybrid sterility in mice.

Nature
2016-02 | Journal article
DOI: 10.1038/nature16931
PMID: 26840484
PMC: PMC4756437
Contributors: Davies B; Hatton E; Altemose N; Hussin JG; Pratto F; Zhang G; Hinch AG; Moralli D; Biggs D; Diaz R et al.
Source: Self-asserted source
Anjali Hinch via Europe PubMed Central

A global reference for human genetic variation.

Nature
2015-10 | Journal article
DOI: 10.1038/nature15393
PMID: 26432245
PMC: PMC4750478
Contributors: 1000 Genomes Project Consortium; Auton A; Brooks LD; Durbin RM; Garrison EP; Kang HM; Korbel JO; Marchini JL; McCarthy S; McVean GA et al.
Source: Self-asserted source
Anjali Hinch via Europe PubMed Central

Recombination in the human Pseudoautosomal region PAR1.

PLoS genetics
2014-07 | Journal article
DOI: 10.1371/journal.pgen.1004503
PMID: 25033397
PMC: PMC4102438
Contributors: Hinch AG; Altemose N; Noor N; Donnelly P; Myers SR
Source: Self-asserted source
Anjali Hinch via Europe PubMed Central

An integrated map of genetic variation from 1,092 human genomes.

Nature
2012-11 | Journal article
DOI: 10.1038/nature11632
PMID: 23128226
PMC: PMC3498066
Contributors: 1000 Genomes Project Consortium; Abecasis GR; Auton A; Brooks LD; DePristo MA; Durbin RM; Handsaker RE; Kang HM; Marth GT; McVean GA
Source: Self-asserted source
Anjali Hinch via Europe PubMed Central

The landscape of recombination in African Americans.

Nature
2011-07 | Journal article
DOI: 10.1038/nature10336
PMID: 21775986
PMC: PMC3154982
Contributors: Hinch AG; Tandon A; Patterson N; Song Y; Rohland N; Palmer CD; Chen GK; Wang K; Buxbaum SG; Akylbekova EL et al.
Source: Self-asserted source
Anjali Hinch via Europe PubMed Central
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