Personal information

No personal information available

Activities

Employment (3)

Cardiff University: Cardiff, Cardiff, GB

2013-09-01 to present | Research Fellow (Biosciences)
Employment
Source: Self-asserted source
Xinsheng Nan

MRC Clinical Sciences Centre: London, London, GB

2006-06-01 to 2013-07-31 | Senior Scientist
Employment
Source: Self-asserted source
Xinsheng Nan

University of Edinburgh: Edinburgh, Edinburgh, GB

2004-07-01 to 2006-05-31 | Research Fellow (Wellcome Centre for Cell Biology)
Employment
Source: Self-asserted source
Xinsheng Nan

Education and qualifications (1)

Peking University: Beijing, Beijing, CN

1987-09-01 to 1990-07-31 | PhD (Biochemistry)
Education
Source: Self-asserted source
Xinsheng Nan

Works (35)

Adenine methylation is very scarce in the <i>Drosophila</i> genome and not erased by the ten-eleven translocation dioxygenase.

eLife
2023-12 | Journal article
Contributors: Boulet M; Gilbert G; Renaud Y; Schmidt-Dengler M; Plantié E; Bertrand R; Nan X; Jurkowski T; Helm M; Vandel L et al.
Source: Self-asserted source
Xinsheng Nan via Europe PubMed Central

VarLOCK: sequencing-independent, rapid detection of SARS-CoV-2 variants of concern for point-of-care testing, qPCR pipelines and national wastewater surveillance.

Scientific reports
2023-11 | Journal article
Contributors: Nan X; Hardinge P; Hoehn S; Dighe SN; Ukeri J; Pease DF; Griffin J; Warrington JI; Saud Z; Hottinger E et al.
Source: Self-asserted source
Xinsheng Nan via Europe PubMed Central

Adenine methylation is very scarce in the drosophila genome and not erased by the Ten Eleven Translocation dioxygenase

2023-09 | Preprint
Contributors: Boulet M; Gilbert G; Renaud Y; Schmidt-Dengler M; Plantié E; Bertrand R; Nan X; Jurkowski T; Helm M; Vandel L et al.
Source: Self-asserted source
Xinsheng Nan via Europe PubMed Central

Brain-derived neurotrophic factor released from blood platelets prevents dendritic atrophy of lesioned adult central nervous system neurons.

Brain communications
2023-03 | Journal article
Contributors: Want A; Nan X; Kokkali E; Barde YA; Morgan JE
Source: Self-asserted source
Xinsheng Nan via Europe PubMed Central

Pronounced sequence specificity of the TET enzyme catalytic domain guides its cellular function.

Science advances
2022-09 | Journal article
Contributors: Ravichandran M; Rafalski D; Davies CI; Ortega-Recalde O; Nan X; Glanfield CR; Kotter A; Misztal K; Wang AH; Wojciechowski M et al.
Source: Self-asserted source
Xinsheng Nan via Europe PubMed Central

VarLOCK - sequencing independent, rapid detection of SARS-CoV-2 variants of concern for point-of-care testing, qPCR pipelines and national wastewater surveillance

2022-01 | Preprint
Contributors: Nan X; Hoehn S; Hardinge P; Dighe SN; Ukeri J; Pease D; Griffin J; Warrington JI; Saud Z; Hottinger E et al.
Source: Self-asserted source
Xinsheng Nan via Europe PubMed Central

The placenta protects the fetal circulation from anxiety-driven elevations in maternal serum levels of brain-derived neurotrophic factor.

Translational psychiatry
2021-01 | Journal article
Contributors: Dingsdale H; Nan X; Garay SM; Mueller A; Sumption LA; Chacón-Fernández P; Martinez-Garay I; Ghevaert C; Barde YA; John RM
Source: Self-asserted source
Xinsheng Nan via Europe PubMed Central

A New Mouse Line Reporting the Translation of Brain-Derived Neurotrophic Factor Using Green Fluorescent Protein.

eNeuro
2020-01 | Journal article
Contributors: Wosnitzka E; Nan X; Nan J; Chacón-Fernández P; Kussmaul L; Schuler M; Hengerer B; Barde YA
Source: Self-asserted source
Xinsheng Nan via Europe PubMed Central

DMRT5, DMRT3 and EMX2 cooperatively repress Gsx2 at the pallium-subpallium boundary to maintain cortical identity in dorsal telencephalic progenitors.

The Journal of neuroscience : the official journal of the Society for Neuroscience
2018-08 | Journal article
Contributors: Desmaris E; Keruzore M; Saulnier A; Ratié L; Assimacopoulos S; De Clercq S; Nan X; Roychoudhury K; Qin S; Kricha S et al.
Source: Self-asserted source
Xinsheng Nan via Europe PubMed Central

Fully human agonist antibodies to TrkB using autocrine cell-based selection from a combinatorial antibody library.

Proceedings of the National Academy of Sciences of the United States of America
2018-07 | Journal article
Contributors: Merkouris S; Barde YA; Binley KE; Allen ND; Stepanov AV; Wu NC; Grande G; Lin CW; Li M; Nan X et al.
Source: Self-asserted source
Xinsheng Nan via Europe PubMed Central

The doublesex-related Dmrta2 safeguards neural progenitor maintenance involving transcriptional regulation of Hes1

Proceedings of the National Academy of Sciences
2017-06 | Journal article
Contributors: Fraser I. Young; Marc Keruzore; Xinsheng Nan; Nicole Gennet; Eric J. Bellefroid; Meng Li
Source: Self-asserted source
Xinsheng Nan via Crossref Metadata Search

DMRT5 Together with DMRT3 Directly Controls Hippocampus Development and Neocortical Area Map Formation.

Cerebral cortex (New York, N.Y. : 1991)
2016-12 | Journal article
Source: Self-asserted source
Xinsheng Nan via Europe PubMed Central

FolR1: a novel cell surface marker for isolating midbrain dopamine neural progenitors and nascent dopamine neurons

Scientific Reports
2016-09-01 | Journal article
Contributors: Nicole Gennet; Claudia Tamburini; Xinsheng Nan; Meng Li
Source: Self-asserted source
Xinsheng Nan via Crossref Metadata Search

Doublesex and mab-3-related transcription factor 5 promotes midbrain dopaminergic identity in pluripotent stem cells by enforcing a ventral-medial progenitor fate.

Proceedings of the National Academy of Sciences of the United States of America
2011-05 | Journal article
Source: Self-asserted source
Xinsheng Nan via Europe PubMed Central

Novel transcription factor involved in neurogenesis

Developmental Biology
2010-08 | Journal article
Contributors: Emma K. Farley; Emily Gale; Nicole Gennet; Xinsheng Nan; Meng Li
Source: Self-asserted source
Xinsheng Nan via Crossref Metadata Search

Gene Silencing by Methyl-CPG-Binding Proteins

Novartis Foundation Symposium 214 - Epigenetics
2007-09 | Other
Contributors: Xinsheng Nan; Sally Cross; Adrian Bird
Source: Self-asserted source
Xinsheng Nan via Crossref Metadata Search

Interaction between chromatin proteins MECP2 and ATRX is disrupted by mutations that cause inherited mental retardation.

Proceedings of the National Academy of Sciences of the United States of America
2007-02 | Journal article
Source: Self-asserted source
Xinsheng Nan via Europe PubMed Central

Regulation of MBD1-mediated transcriptional repression by SUMO and PIAS proteins

The EMBO Journal
2006-10 | Journal article
Contributors: Matthew J Lyst; Xinsheng Nan; Irina Stancheva
Source: Self-asserted source
Xinsheng Nan via Crossref Metadata Search

Testing for association between MeCP2 and the brahma-associated SWI/SNF chromatin-remodeling complex

Nature Genetics
2006-09 | Journal article
Contributors: Keping Hu; Xinsheng Nan; Adrian Bird; Weidong Wang
Source: Self-asserted source
Xinsheng Nan via Crossref Metadata Search

Potent stimulation of gene expression by histone deacetylase inhibitors on transiently transfected DNA

Biochemical and Biophysical Research Communications
2004-11 | Journal article
Contributors: Xinsheng Nan; Laura Hyndman; Nike Agbi; David J. Porteous; A. Christopher Boyd
Source: Self-asserted source
Xinsheng Nan via Crossref Metadata Search

HIV-1 Tat protein transduction domain peptide facilitates gene transfer in combination with cationic liposomes

Journal of Controlled Release
2004-10 | Journal article
Contributors: Laura Hyndman; Jerome L. Lemoine; Leaf Huang; David J. Porteous; A. Christopher Boyd; Xinsheng Nan
Source: Self-asserted source
Xinsheng Nan via Crossref Metadata Search

The origin of the genetical diversity of Microtus mandarinus chromosomes

Hereditas
2004-01-06 | Journal article
Source: Self-asserted source
Xinsheng Nan

The Methyl-CpG-binding Protein MeCP2 Links DNA Methylation to Histone Methylation

Journal of Biological Chemistry
2002-11-09 | Journal article
Contributors: François Fuks; Paul J. Hurd; Daniel Wolf; Xinsheng Nan; Adrian P. Bird; Tony Kouzarides
Source: Self-asserted source
Xinsheng Nan via Crossref Metadata Search

The biological functions of the methyl-CpG-binding protein MeCP2 and its implication in Rett syndrome

Brain and Development
2001 | Journal article
Contributors: Xinsheng Nan; Adrian Bird
Source: Self-asserted source
Xinsheng Nan via Crossref Metadata Search

The solution structure of the domain from MeCP2 that binds to methylated DNA

1999-10-08 | Other
Contributors: R.I.D. Wakefield; B.O. Smith; X. Nan; A. Free; A. Soteriou; D. Uhrin; A. Bird; P.N. Barlow
Source: Self-asserted source
Xinsheng Nan via Crossref Metadata Search

The solution structure of the domain from MeCP2 that binds to methylated DNA

Journal of Molecular Biology
1999-09 | Journal article
Contributors: Robert I.D Wakefield; Brian O Smith; Xinsheng Nan; Andrew Free; Alice Soteriou; Dusan Uhrin; Adrian P Bird; Paul N Barlow
Source: Self-asserted source
Xinsheng Nan via Crossref Metadata Search

Gene silencing by methyl-CpG-binding proteins.

Novartis Foundation symposium
1998 | Journal article
PMID: 9601009
Source: Self-asserted source
Xinsheng Nan via Europe PubMed Central

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex.

Nature
1998-05 | Journal article
PMID: 9620804
Source: Self-asserted source
Xinsheng Nan via Europe PubMed Central

A component of the transcriptional represser MeCP1 shares a motif with DNA methyltransferase and HRX proteins

Nature Genetics
1997-07 | Journal article
Contributors: Sally H. Cross; Richard R. Meehan; Xinsheng Nan; Adrian Bird
Source: Self-asserted source
Xinsheng Nan via Crossref Metadata Search

MeCP2 Is a Transcriptional Repressor with Abundant Binding Sites in Genomic Chromatin

Cell
1997-02 | Journal article
Contributors: Xinsheng Nan; F.Javier Campoy; Adrian Bird
Source: Self-asserted source
Xinsheng Nan via Crossref Metadata Search

DNA methylation specifies chromosomal localization of MeCP2.

Molecular and Cellular Biology
1996-01 | Journal article
Contributors: X Nan; P Tate; E Li; A Bird
Source: Self-asserted source
Xinsheng Nan via Crossref Metadata Search

Studies of DNA methylation in animals.

Journal of cell science. Supplement
1995 | Journal article
PMID: 8655645
Source: Self-asserted source
Xinsheng Nan via Europe PubMed Central

Purification of CpG islands using a methylated DNA binding column

Nature Genetics
1994-03 | Journal article
Contributors: Sally H. Cross; Jillian A. Charlton; Xinsheng Nan; Adrian P. Bird
Source: Self-asserted source
Xinsheng Nan via Crossref Metadata Search

Dissection of the methyl-CpG binding domain from the chromosomal protein MeCP2

Nucleic Acids Research
1993 | Journal article
Contributors: Xinsheng Nan; Richard R. Meehan; Adrian Bird
Source: Self-asserted source
Xinsheng Nan via Crossref Metadata Search

Transcriptional repression by methylation of CpG.

Journal of cell science. Supplement
1992 | Journal article
PMID: 1297654
Source: Self-asserted source
Xinsheng Nan via Europe PubMed Central