Personal information

Activities

Employment (3)

Sunway University: Bandar Sunway, Selangor, MY

2013-07-15 to present | Professor (Biological Sciences)
Employment
Source: Self-asserted source
Kuan Tan

Johnson and Johnson: NJ, NJ, US

2004 to 2008 | Principal Scientist (Group Leader) (Consumer Product)
Employment
Source: Self-asserted source
Kuan Tan

Institute of Molecular and Cell Biology: Singapore, SG

2001 to 2003 | Research Scientist (Cancer Biology (Apoptosis Signalling))
Employment
Source: Self-asserted source
Kuan Tan

Education and qualifications (3)

University of Southern Queensland: Toowoomba, QLD, AU

2004 to 2006 | MBA (Business Administration)
Education
Source: Self-asserted source
Kuan Tan

Iowa State University: Ames, IA, US

1987-09-30 to 1993-12-31 | Ph.D (Biochemistry and Biophysics)
Education
Source: Self-asserted source
Kuan Tan

Iowa State University: Ames, IA, US

1983-09-25 to 1987-09-01 | B.S (Biochemistry)
Education
Source: Self-asserted source
Kuan Tan

Professional activities (4)

New York Academy of Sciences: New York, NY, US

Membership
Source: Self-asserted source
Kuan Tan

American Association for the Advancement of Science: DC, DC, US

Membership
Source: Self-asserted source
Kuan Tan

American Society for Cell Biology: Bethesda, MD, US

2017-01 to present
Membership
Source: Self-asserted source
Kuan Tan

Sunway University: Bandar Sunway, Selangor, MY

2017-01-03 | Research Director (BIological Sciences)
Distinction
Source: Self-asserted source
Kuan Tan

Works (30)

Photoprotective activities of Lignosus rhinocerus in UV-irradiated human keratinocytes

Journal of Ethnopharmacology
2022-12 | Journal article
Contributors: Hui Sin Lim; Samson Eugin Simon; Yoon-Yen Yow; R. Saidur; Kuan Onn Tan
Source: check_circle
Crossref

Spirulina platensis Suppressed iNOS and Proinflammatory Cytokines in Lipopolysaccharide-Induced BV2 Microglia

Metabolites
2022-11-20 | Journal article
Contributors: Ee-Ling Ngu; Cheng-Yau Tan; Nicole Jean-Yean Lai; Kah-Hui Wong; Siew-Huah Lim; Long Chiau Ming; Kuan-Onn Tan; Siew-Moi Phang; Yoon-Yen Yow
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Engineered Oncolytic Adenoviruses: An Emerging Approach for Cancer Therapy

Pathogens
2022-10 | Journal article | Author
Contributors: Ee Wern Tan; Noraini Abd-Aziz; Chit-Laa Poh; Kuan Tan
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

New synthetic phenylquinazoline derivatives induce apoptosis by targeting the pro-survival members of the BCL-2 family

Bioorganic & Medicinal Chemistry Letters
2022-07 | Journal article
Part of ISSN: 0960-894X
Contributors: Kuan Tan; Samson Eugin Simon; Usman Ahmed; Syed Muhammad Saad; Ayaz Anwar; Khalid Mohammed Khan; Ee Wern Tan; Kuan Onn Tan
Source: Self-asserted source
Kuan Tan

Potential anti-acanthamoebic effects through inhibition of CYP51 by novel quinazolinones

Acta Tropica
2022-07 | Journal article
Part of ISSN: 0001-706X
Contributors: Kuan Tan; Usman Ahmed; Keat-Yie Ho; Samson Eugin Simon; Syed Muhammad Saad; Seng-Kai Ong; Areeba Anwar; Kuan Onn Tan; Nanthini Sridewi; Khalid Mohammed Khan et al.
Source: Self-asserted source
Kuan Tan

Alpha-Mangostin Activates MOAP-1 Tumor Suppressor and Mitochondrial Signaling in MCF-7 Human Breast Cancer Cells

Evidence-Based Complementary and Alternative Medicine
2022-01-17 | Journal article
Contributors: Samson Eugin Simon; Hui Sin Lim; Fairen Angelin Jayakumar; Ee Wern Tan; Kuan Onn Tan; Siyaram Pandey
Source: check_circle
Crossref

Investigating the impact of UV irradiated graphene oxide on human breast cancer cells

Materials Today Communications
2021-12 | Journal article
Part of ISSN: 2352-4928
Source: Self-asserted source
Kuan Tan

Molecular mechanism of L-SP40 peptide and in vivo efficacy against EV-A71 in neonatal mice

Life Sciences
2021-12 | Journal article
Part of ISSN: 0024-3205
Source: Self-asserted source
Kuan Tan

Emerging strategies for sensitization of therapy resistant tumors toward cancer therapeutics by targeting the Bcl-2 family, TGF-β, Wnt/β-Catenin, RASSF and miRNA regulated signaling pathways

The International Journal of Biochemistry & Cell Biology
2021-08 | Journal article
Contributors: Tarmarajen Veerasamy; Samson Eugin Simon; Kuan Onn Tan
Source: check_circle
Crossref

Tricistronic expression of MOAP-1, Bax and RASSF1A in cancer cells enhances chemo-sensitization that requires BH3L domain of MOAP-1

Journal of Cancer Research and Clinical Oncology
2020-07-06 | Journal article
Contributors: Yong Hoi Lee; Siew Wai Pang; Esther Revai Lechtich; Khalid Shah; Samson Eugin Simon; Suriyan Ponnusamy; Ramesh Narayanan; Chit Laa Poh; Kuan Onn Tan
Source: check_circle
Crossref

Human Embryonic Stem Cell-Derived Neural Lineages as In Vitro Models for Screening the Neuroprotective Properties of Lignosus rhinocerus (Cooke) Ryvarden

Biomed Research International
2019-08-19 | Journal article
Source: Self-asserted source
Kuan Tan

Development of live attenuated Enterovirus 71 vaccine strains that confer protection against lethal challenge in mice.

Scientific reports
2019-03-18 | Journal article
Source: Self-asserted source
Kuan Tan

PNMA family: Protein interaction network and cell signalling pathways implicated in cancer and apoptosis

Cellular Signalling
2018-05 | Journal article
Contributors: Siew Wai Pang; Chandrajit Lahiri; Chit Laa Poh; Kuan Onn Tan
Source: check_circle
Crossref

Characterization of significant molecular determinants of virulence of Enterovirus 71 sub-genotype B4 in Rhabdomyosarcoma cells

Virus Research
2017-06 | Journal article
Part of ISSN: 0168-1702
Source: Self-asserted source
Kuan Tan

Identification of molecular determinants of cell culture growth characteristics of Enterovirus 71

Virology Journal
2016-12 | Journal article
Part of ISSN: 1743-422X
Source: Self-asserted source
Kuan Tan

Distinct functional domains of PNMA5 mediate protein–protein interaction, nuclear localization, and apoptosis signaling in human cancer cells

Journal of Cancer Research and Clinical Oncology
2016-09 | Journal article
Contributors: Yong Hoi Lee; Siew Wai Pang; Chit Laa Poh; Kuan Onn Tan
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

PNMA2 mediates heterodimeric interactions and antagonizes chemo-sensitizing activities mediated by members of PNMA family

Biochemical and Biophysical Research Communications
2016-04 | Journal article
Contributors: Yong Hoi Lee; Siew Wai Pang; Kuan Onn Tan
Source: Self-asserted source
Kuan Tan via Crossref Metadata Search

Pluripotent Human embryonic stem cell derived neural lineages for in vitro modelling of enterovirus 71 infection and therapy

Virol J
2016-01-06 | Journal article
Contributors: May Shin Yap; Yin Quan Tang; Yin Yeo; Wei Ling Lim; Lee Wei Lim; Kuan Onn Tan; Mark Richards; Iekhsan Othman; Chit Laa Poh; Boon Chin Heng
Source: Self-asserted source
Kuan Tan via Crossref Metadata Search

MAP-1 is a mitochondrial effector of Bax

Proceedings of the National Academy of Sciences of the United States of America
2005 | Journal article
EID:

2-s2.0-26844504903

Contributors: Tan, K.O.; Fu, N.Y.; Sukumaran, S.K.; Chan, S.-L.; Kang, J.H.; Poon, K.L.; Chen, B.S.; Yu, V.C.
Source: Self-asserted source
Kuan Tan via Scopus - Elsevier

Identification of chelerythrine as an inhibitor of BclXL function

Journal of Biological Chemistry
2003 | Journal article
EID:

2-s2.0-0038081194

Contributors: Chan, S.-L.; Lee, M.C.; Tan, K.O.; Yang, L.-K.; Lee, A.S.Y.; Flotow, H.; Fu, N.Y.; Butler, M.S.; Soejarto, D.D.; Buss, A.D. et al.
Source: Self-asserted source
Kuan Tan via Scopus - Elsevier

MAP-1 Is a Putative Ligand for the Multidomain Proapoptotic Protein Bax

Molecular Mechanisms of Programmed Cell Death
2003 | Book chapter
Part of ISBN: 9781441934048
Part of ISBN: 9781475758900
Source: Self-asserted source
Kuan Tan
grade
Preferred source (of 2)‎

Mitochondrial translocation of cofilin is an early step in apoptosis induction

Nature Cell Biology
2003 | Journal article
EID:

2-s2.0-0344668558

Contributors: Chua, B.T.; Volbracht, C.; Tan, K.O.; Li, R.; Yu, V.C.; Li, P.
Source: Self-asserted source
Kuan Tan via Scopus - Elsevier

MAP-1, a Novel Proapoptotic Protein Containing a BH3-like Motif That Associates with Bax through Its Bcl-2 Homology Domains

Journal of Biological Chemistry
2001 | Journal article
EID:

2-s2.0-0035951847

Contributors: Tan, K.O.; Tan, K.M.L.; Chan, S.-L.; Yee, K.S.Y.; Bévort, M.; Ang, K.C.; Yu, V.C.
Source: Self-asserted source
Kuan Tan via Scopus - Elsevier

The Caenorhabditis elegans Sex-determining Protein FEM-2 and Its Human Homologue, hFEM-2, Are Ca2+/Calmodulin-dependent Protein Kinase Phosphatases That Promote Apoptosis

Journal of Biological Chemistry
2001 | Journal article
EID:

2-s2.0-0035941193

Contributors: Tan, K.M.L.; Chan, S.-L.; Tan, K.O.; Yu, V.C.
Source: Self-asserted source
Kuan Tan via Scopus - Elsevier

A novel BH3-like domain in BID is required for intramolecular interaction and autoinhibition of pro-apoptotic activity

Journal of Biological Chemistry
1999 | Journal article
EID:

2-s2.0-0038832563

Contributors: Tan, K.O.; Tan, K.M.L.; Yu, V.C.
Source: Self-asserted source
Kuan Tan via Scopus - Elsevier

F1Aα, a death receptor-binding protein homologous to the Caenorhabditis elegans sex-determining protein, FEM-1, is a caspase substrate that mediates apoptosis

Journal of Biological Chemistry
1999 | Journal article
EID:

2-s2.0-0033527451

Contributors: Chan, S.-L.; Tan, K.-O.; Zhang, L.; Yee, K.S.Y.; Ronca, F.; Chan, M.-Y.; Yu, V.C.
Source: Self-asserted source
Kuan Tan via Scopus - Elsevier

Molecular characterization of avian muscle titin

Journal of Biological Chemistry
1993 | Journal article
EID:

2-s2.0-0027377088

Contributors: Tan, K.O.; Sater, G.R.; Myers, A.M.; Robson, R.M.; Huiatt, T.W.
Source: Self-asserted source
Kuan Tan via Scopus - Elsevier

Investigating the impact of UV irradiated graphene oxide on human breast cancer cells

Journal article
Source: Self-asserted source
Kuan Tan

Molecular mechanisms of programmed cell death

Book chapter
Source: Self-asserted source
Kuan Tan

Pathogenicity and Immunogenicity of Adenovirus

Encyclopedia entry
Contributors: Kuan Tan
Source: Self-asserted source
Kuan Tan