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Employment (4)

Vecna: College Park, MD, US

2005 to 2020-03-01 | Director of Bioinformatics (Medical)
Employment
Source: Self-asserted source
Christopher N Larsen

Cognia Corp: Manhattan, NY, US

2001 to 2005 | Director (Product Development)
Employment
Source: Self-asserted source
Christopher N Larsen

Phillips Academy: Andover, MA, US

2000 to 2001 | Instructor in Chemistry and Biology (Science)
Employment
Source: Self-asserted source
Christopher N Larsen

Harvard Medical School: Boston, MA, US

1996 to 2000 | Research Associate (Cell Biology)
Employment
Source: Self-asserted source
Christopher N Larsen

Education and qualifications (2)

Emory University: Atlanta, GA, US

1989 to 1996 | Ph.D. (Biochemistry)
Education
Source: Self-asserted source
Christopher N Larsen

Mercer University: Macon, GA, US

1984 to 1989 | BA, BS (Chemistry, Biology)
Education
Source: Self-asserted source
Christopher N Larsen

Funding (7)

Advanced Infection Control methods for Antimicrobial Drug Resistance and Pathogen

2010-05-01 to 2011-04-30 | Grant
National Institute of Nursing Research (Bethesda, US)
URL: https://app.dimensions.ai/details/grant/grant.2655260
GRANT_NUMBER: R43NR012128
Source: Self-asserted source
Christopher N Larsen via DimensionsWizard

Development of an Integrated Database Management System for Biodefense Research

2007-05-10 to 2007-11-09 | Grant
United States Department of Defense (Washington D.C., US)
URL: https://app.dimensions.ai/details/grant/grant.4427001
GRANT_NUMBER: W81XWH-07-C-0075
Source: Self-asserted source
Christopher N Larsen via DimensionsWizard

Robotic Force Health Protection from Chem-Bio Agents and IEDs

2006-11-08 to 2007-12-17 | Grant
United States Department of the Army (Arlington, US)
URL: https://app.dimensions.ai/details/grant/grant.4392145
GRANT_NUMBER: W81XWH-07-C-0016
Source: Self-asserted source
Christopher N Larsen via DimensionsWizard

Comprehensive Database Resource on Protein Localization

2003-02 to 2006-05 | Grant
National Science Foundation (VA, VA, US)
GRANT_NUMBER: 0239206
Source: Self-asserted source
Christopher N Larsen
grade
Preferred source (of 2)‎

Structure based prediction of protein modifications

2002-08-01 to 2003-01-31 | Grant
National Institute of General Medical Sciences (Bethesda, US)
URL: https://app.dimensions.ai/details/grant/grant.2650338
GRANT_NUMBER: R43GM066514
Source: Self-asserted source
Christopher N Larsen via DimensionsWizard

Curation Tools and Experiences

2002-05 to 2002-07 | Grant
National Science Foundation (VA, VA, US)
GRANT_NUMBER:

0230718
Source: Self-asserted source
Christopher N Larsen

NASL REPEAT DOMAIN AND PROTEASOME FUNCTION

1998-07-09 to 1999-01-01 | Grant
National Institute of General Medical Sciences (Bethesda, US)
URL: https://app.dimensions.ai/details/grant/grant.2380979
GRANT_NUMBER: F32GM019359
Source: Self-asserted source
Christopher N Larsen via DimensionsWizard

Works (24)

Mat_peptide: comprehensive annotation of mature peptides from polyproteins in five virus families

Bioinformatics
2020-03-01 | Journal article
DOI: 10.1093/bioinformatics/btz777
Contributors: Christopher N Larsen; Guangyu Sun; Xiaomei Li; Sam Zaremba; Hongtao Zhao; Sherry He; Liwei Zhou; Sanjeev Kumar; Vince Desborough; Edward B Klem et al.
Source: check_circle
Crossref

Hepatitis C Virus Database and Bioinformatics Analysis Tools in the Virus Pathogen Resource (ViPR).

Methods Mol Biol.
2019-01 | Journal article
PMID: 30593617
Source: Self-asserted source
Christopher N Larsen

Influenza Research Database: An integrated bioinformatics resource for influenza virus research.

2017 | Journal article
DOI: 10.1093/nar/gkw857
Source: Self-asserted source
Christopher N Larsen
grade
Preferred source (of 2)‎

Comprehensive Annotation of Mature Peptides and Genotypes for Zika Virus

PLOS ONE
2017-01-26 | Journal article
DOI: 10.1371/journal.pone.0170462
Contributors: Guangyu Sun; Tony T. Wang; Christopher N. Larsen; Nicole Baumgarth; Edward B. Klem; Richard H. Scheuermann
Source: check_circle
Crossref

Genetic changes found in a distinct clade of Enterovirus D68 associated with paralysis during the 2014 outbreak.

2016 | Journal article
DOI: 10.1093/ve/vew015
Source: Self-asserted source
Christopher N Larsen

Metadata-driven comparative analysis tool for sequences (metaBiographical Sketch 2-27-2017 pg.3 CATS): an automated process for identifying significant sequence variations that correlate with virus attributes.

2013 | Journal article
DOI: 10.1016/j.virol.2013.08.021
Source: Self-asserted source
Christopher N Larsen

Influenza research database: an integrated bioinformatics resource for influenza research and surveillance.

Influenza Other Respir Viruses
2012 | Journal article
DOI: 10.1111/j.1750-2659.2011.00331.x
Source: Self-asserted source
Christopher N Larsen

ViPR: an open bioinformatics database and analysis resource for virology research.

2012 | Journal article
DOI: 10.1093/nar/gkr859
Source: Self-asserted source
Christopher N Larsen

Virus Pathogen Database and Analysis Resource (ViPR): A Comprehensive Bioinformatics Database and Analysis Resource for the Coronavirus Research Community

Viruses
2012-11 | Journal article
DOI: 10.3390/v4113209
Contributors: Brett Pickett; Douglas Greer; Yun Zhang; Lucy Stewart; Liwei Zhou; Guangyu Sun; Zhiping Gu; Sanjeev Kumar; Sam Zaremba; Christopher Larsen et al.
Source: Self-asserted source
Christopher N Larsen via Crossref Metadata Search

The SUMO System: An Overview

SUMO Protocols
2009 | Other
DOI: 10.1007/978-1-59745-566-4_1
Contributors: Helle D. Ulrich
Source: Self-asserted source
Christopher N Larsen via Crossref Metadata Search

BioHealthBase: informatics support in the elucidation of influenza virus host pathogen interactions and virulence

Nucleic Acids Research
2007 | Journal article
DOI: 10.1093/nar/gkm905
Contributors: B. Squires; C. Macken; A. Garcia-Sastre; S. Godbole; J. Noronha; V. Hunt; R. Chang; C. N. Larsen; E. Klem; K. Biersack et al.
Source: Self-asserted source
Christopher N Larsen via Crossref Metadata Search

The Ubiquitin Superfamily:  Members, Features, and Phylogenies

Journal of Proteome Research
2002-10 | Journal article
DOI: 10.1021/pr025522n
Contributors: Christopher N. Larsen; Hailin Wang
Source: Self-asserted source
Christopher N Larsen via Crossref Metadata Search

The binding site for UCH-L3 on ubiquitin: mutagenesis and NMR studies on the complex between ubiquitin and UCH-L3

Journal of Molecular Biology
1999-09 | Journal article
DOI: 10.1006/jmbi.1999.3038
Contributors: Keith D.Wilkinson; Elvan Laleli-Sahin; Jeffrey Urbauer; Christopher N. Larsen; Grace Hong Shih; Arthur L. Haas; Scott T.R.Walsh; A.Joshua Wand
Source: Self-asserted source
Christopher N Larsen via Crossref Metadata Search

Functional analysis of the proteasome regulatory particle.

1999-04-01 | Journal article
PMID: 10363642
Source: Self-asserted source
Christopher N Larsen

Active site mutants in the six regulatory particle ATPases reveal multiple roles for ATP in the proteasome.

1998-09-01 | Journal article
PMC: 1170820
Source: Self-asserted source
Christopher N Larsen

Substrate Specificity of Deubiquitinating Enzymes:  Ubiquitin C-Terminal Hydrolases †

Biochemistry
1998-03 | Journal article
DOI: 10.1021/bi972274d
Contributors: Christopher N. Larsen; Bryan A. Krantz; Keith D. Wilkinson
Source: Self-asserted source
Christopher N Larsen via Crossref Metadata Search

DEUBIQUITINATING ENZYME UCH-L3 (HUMAN) AT 1.8 ANGSTROM RESOLUTION

1998-01 | Other
DOI: 10.2210/pdb1uch/pdb
Contributors: S.C. Johnston; C.N. Larsen; W.J. Cook; K.D. Wilkinson; C.P. Hill
Source: Self-asserted source
Christopher N Larsen via Crossref Metadata Search

Protein Translocation Channels in the Proteasome and Other Proteases

Cell
1997-11 | Journal article
DOI: 10.1016/s0092-8674(00)80427-4
Contributors: Christopher N Larsen; Daniel Finley
Source: Self-asserted source
Christopher N Larsen via Crossref Metadata Search

Crystal structure of a deubiquitinating enzyme (human UCH-L3) at 1.8 Å resolution

The EMBO Journal
1997-07-01 | Journal article
DOI: 10.1093/emboj/16.13.3787
Contributors: Steven C. Johnston; Christopher N. Larsen; William J. Cook; Keith D. Wilkinson; Christopher P. Hill
Source: Self-asserted source
Christopher N Larsen via Crossref Metadata Search

Substrate Binding and Catalysis by Ubiquitin C-Terminal Hydrolases:  Identification of Two Active Site Residues †

Biochemistry
1996-01 | Journal article
DOI: 10.1021/bi960099f
Contributors: Christopher N. Larsen; Joanne S. Price; Keith D. Wilkinson
Source: Self-asserted source
Christopher N Larsen via Crossref Metadata Search

Metabolism of the polyubiquitin degradation signal: structure, mechanism, and role of isopeptidase T

Biochemistry
1995-11 | Journal article
DOI: 10.1021/bi00044a032
Contributors: Keith D. Wilkinson; Valery L. Tashayev; Lydia B. O'Connor; Christopher N. Larsen; Eileen Kasperek; Cecile M. Pickart
Source: Self-asserted source
Christopher N Larsen via Crossref Metadata Search

Comparisons of neuronal (PGP 9.5) and non-neuronal ubiquitin C -terminal hydrolases

Biochemical Society Transactions
1992-08 | Journal article
DOI: 10.1042/bst0200631
Contributors: Keith D. Wilkinson; Seema Deshpande; Christopher N. Larsen
Source: Self-asserted source
Christopher N Larsen via Crossref Metadata Search

Ubiquitin

SpringerReference
Other
DOI: 10.1007/springerreference_108116
Source: Self-asserted source
Christopher N Larsen via Crossref Metadata Search

UCH

Encyclopedia of Cancer
Other
DOI: 10.1007/978-3-540-47648-1_6090
Source: Self-asserted source
Christopher N Larsen via Crossref Metadata Search
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