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Employment (8)

University of Bergen: Bergen, Vestland, NO

2022-03-01 to present | Senior researcher (Medicine)
Employment
Source: Self-asserted source
Kim Brügger

University of Bergen: Bergen, Vestland, NO

2018-09-01 to 2021-03-01 | Senior engineer (Informatics)
Employment
Source: Self-asserted source
Kim Brügger

Cambridge University Hospitals: Cambridge, Cambridgeshire, GB

2018-08-01 to 2018-09-01 | Lead bioinformatican (Genetics)
Employment
Source: Self-asserted source
Kim Brügger

Cambridge University Hospitals Neurosciences: Cambridge, Cambridgeshire, GB

2013-07-01 to 2014-08-01 | Bioinformatican (Genetics)
Employment
Source: Self-asserted source
Kim Brügger

University of Cambridge: Cambridge, Cambridgeshire, GB

2012-01-01 to 2013-07-01 | Head of bioinformatics/Senior research assistant (Genetics)
Employment
Source: Self-asserted source
Kim Brügger

University of Cambridge: Cambridge, Cambridgeshire, GB

2010-01-01 to 2012-03-01 | Bioinformatican (Genetics)
Employment
Source: Self-asserted source
Kim Brügger

Wellcome Sanger Institute: Cambridge, GB

2008-11-01 to 2010-03-01 | senior computational biologist
Employment
Source: Self-asserted source
Kim Brügger

University of Copenhagen: Copenhagen, DK

2006-11-01 to 2008-11-01 | Post doc (Biology)
Employment
Source: Self-asserted source
Kim Brügger

Education and qualifications (2)

University of Copenhagen: Copenhagen, DK

2003 to 2006 | Ph.D
Education
Source: Self-asserted source
Kim Brügger

University of Copenhagen: Copenhagen, DK

1995 to 2002 | Master (Biology)
Education
Source: Self-asserted source
Kim Brügger

Funding (1)

Clinical NGS analysis

2019-01 to 2019-06 | Grant
Norbis (Bergen, NO)
URL: https://norbis.w.uib.no/
Source: Self-asserted source
Kim Brügger

Works (36)

Development and validation of a universal blood donor genotyping platform: a multinational prospective study.

Blood advances
2020-08 | Journal article
DOI: 10.1182/bloodadvances.2020001894
PMID: 32750130
PMC: PMC7422129
Contributors: Gleadall NS; Veldhuisen B; Gollub J; Butterworth AS; Ord J; Penkett CJ; Timmer TC; Sauer CM; van der Bolt N; Brown C et al.
Source: Self-asserted source
Kim Brügger via Europe PubMed Central

RICOPILI: Rapid Imputation for COnsortias PIpeLIne.

Bioinformatics (Oxford, England)
2020-02 | Journal article
DOI: 10.1093/bioinformatics/btz633
PMID: 31393554
PMC: PMC7868045
Contributors: Lam M; Awasthi S; Watson HJ; Goldstein J; Panagiotaropoulou G; Trubetskoy V; Karlsson R; Frei O; Fan CC; De Witte W et al.
Source: Self-asserted source
Kim Brügger via Europe PubMed Central

One byte at a time: evidencing the quality of clinical service next-generation sequencing for germline and somatic variants.

European journal of human genetics : EJHG
2019-09 | Journal article
DOI: 10.1038/s41431-019-0515-1
PMID: 31570784
PMC: PMC6974611
Contributors: Gutowska-Ding MW; Deans ZC; Roos C; Matilainen J; Khawaja F; Brügger K; Ahn JW; Boustred C; Patton SJ
Source: Self-asserted source
Kim Brügger via Europe PubMed Central

Discovery of a novel dominant mutation in the REN gene after forty years of renal disease: a case report.

BMC nephrology
2017-07 | Journal article
DOI: 10.1186/s12882-017-0631-5
PMID: 28701203
PMC: PMC5508479
Contributors: Clissold RL; Clarke HC; Spasic-Boskovic O; Brugger K; Abbs S; Bingham C; Shaw-Smith C
Source: Self-asserted source
Kim Brügger via Europe PubMed Central

Male child with somatic mosaic Osteopathia Striata with Cranial Sclerosis caused by a novel pathogenic AMER1 frameshift mutation.

American journal of medical genetics. Part A
2017-05 | Journal article
DOI: 10.1002/ajmg.a.38261
PMID: 28497491
Contributors: Hague J; Delon I; Brugger K; Martin H; Sparnon L; Simonic I; Abbs S; Park SM
Source: Self-asserted source
Kim Brügger via Europe PubMed Central

Practice guidelines for development and validation of software, with particular focus on bioinformatics pipelines for processing NGS data in clinical diagnostic laboratories

2017-05 | Preprint
DOI: 10.7287/peerj.preprints.2996v1
PPR: PPR37303
Contributors: Whiffin N; Brugger K; Ahn JW
Source: Self-asserted source
Kim Brügger via Europe PubMed Central

Mosaicism for a pathogenic MFN2 mutation causes minimal clinical features of CMT2A in the parent of a severely affected child.

Neurogenetics
2017-01 | Journal article
DOI: 10.1007/s10048-016-0504-2
PMID: 28063088
PMC: PMC5243894
Contributors: Schon K; Spasic-Boskovic O; Brugger K; Graves TD; Abbs S; Park SM; Ambegaonkar G; Armstrong R
Source: Self-asserted source
Kim Brügger via Europe PubMed Central

Comprehensive Screening of Eight Known Causative Genes in Congenital Hypothyroidism With Gland-in-Situ.

The Journal of clinical endocrinology and metabolism
2016-08 | Journal article
DOI: 10.1210/jc.2016-1879
PMID: 27525530
PMC: PMC5155683
Contributors: Nicholas AK; Serra EG; Cangul H; Alyaarubi S; Ullah I; Schoenmakers E; Deeb A; Habeb AM; Almaghamsi M; Peters C et al.
Source: Self-asserted source
Kim Brügger via Europe PubMed Central

gEVAL - a web-based browser for evaluating genome assemblies.

Bioinformatics (Oxford, England)
2016-04 | Journal article
DOI: 10.1093/bioinformatics/btw159
PMID: 27153597
PMC: PMC4978925
Contributors: Chow W; Brugger K; Caccamo M; Sealy I; Torrance J; Howe K
Source: Self-asserted source
Kim Brügger via Europe PubMed Central

Molecularly proven mosaicism in phenotypically normal parent of a girl with Freeman-Sheldon Syndrome caused by a pathogenic MYH3 mutation.

American journal of medical genetics. Part A
2016-03 | Journal article
DOI: 10.1002/ajmg.a.37631
PMID: 26996280
Contributors: Hague J; Delon I; Brugger K; Martin H; Abbs S; Park SM
Source: Self-asserted source
Kim Brügger via Europe PubMed Central

Epigenetic analysis of regulatory T cells using multiplex bisulfite sequencing.

European journal of immunology
2015-10 | Journal article
DOI: 10.1002/eji.201545646
PMID: 26420295
PMC: PMC4832369
Contributors: Rainbow DB; Yang X; Burren O; Pekalski ML; Smyth DJ; Klarqvist MD; Penkett CJ; Brugger K; Martin H; Todd JA et al.
Source: Self-asserted source
Kim Brügger via Europe PubMed Central

Somatic Mutation Screening Using Archival Formalin-Fixed, Paraffin-Embedded Tissues by Fluidigm Multiplex PCR and Illumina Sequencing.

The Journal of molecular diagnostics : JMD
2015-07 | Journal article
DOI: 10.1016/j.jmoldx.2015.04.008
PMID: 26165823
PMC: PMC4597275
Contributors: Wang M; Escudero-Ibarz L; Moody S; Zeng N; Clipson A; Huang Y; Xue X; Grigoropoulos NF; Barrans S; Worrillow L et al.
Source: Self-asserted source
Kim Brügger via Europe PubMed Central

HIV Drug Therapy in the Americas 16-18 April 2015, Mexico City, Mexico.

Journal of the International AIDS Society
2015-04 | Journal article
DOI: 10.7448/ias.18.3.20177
PMID: 25967936
PMC: PMC4401943
Source: Self-asserted source
Kim Brügger via Europe PubMed Central

KLF2 mutation is the most frequent somatic change in splenic marginal zone lymphoma and identifies a subset with distinct genotype.

Leukemia
2014-11 | Journal article
DOI: 10.1038/leu.2014.330
PMID: 25428260
Contributors: Clipson A; Wang M; de Leval L; Ashton-Key M; Wotherspoon A; Vassiliou G; Bolli N; Grove C; Moody S; Escudero-Ibarz L et al.
Source: Self-asserted source
Kim Brügger via Europe PubMed Central

Unilateral hypoplastic kidney - a novel highly penetrant feature of familial juvenile hyperuricaemic nephropathy.

BMC nephrology
2014-05 | Journal article
DOI: 10.1186/1471-2369-15-76
PMID: 24886545
PMC: PMC4036736
Contributors: Plumb LA; Marlais M; Bierzynska A; Martin H; Brugger K; Abbs S; Saleem MA
Source: Self-asserted source
Kim Brügger via Europe PubMed Central

Draft Genome Sequence of Serratia sp. Strain ATCC 39006, a Model Bacterium for Analysis of the Biosynthesis and Regulation of Prodigiosin, a Carbapenem, and Gas Vesicles.

Genome announcements
2013-12 | Journal article
DOI: 10.1128/genomea.01039-13
PMID: 24336377
PMC: PMC3861430
Contributors: Fineran PC; Iglesias Cans MC; Ramsay JP; Wilf NM; Cossyleon D; McNeil MB; Williamson NR; Monson RE; Becher SA; Stanton JA et al.
Source: Self-asserted source
Kim Brügger via Europe PubMed Central

Structure and mechanism of the CMR complex for CRISPR-mediated antiviral immunity.

Molecular cell
2012-01 | Journal article
DOI: 10.1016/j.molcel.2011.12.013
PMID: 22227115
PMC: PMC3381847
Contributors: Zhang J; Rouillon C; Kerou M; Reeks J; Brugger K; Graham S; Reimann J; Cannone G; Liu H; Albers SV et al.
Source: Self-asserted source
Kim Brügger via Europe PubMed Central

Genome analyses of Icelandic strains of Sulfolobus islandicus, model organisms for genetic and virus-host interaction studies.

Journal of bacteriology
2011-01 | Journal article
DOI: 10.1128/jb.01487-10
PMID: 21278296
PMC: PMC3067641
Contributors: Guo L; Brügger K; Liu C; Shah SA; Zheng H; Zhu Y; Wang S; Lillestøl RK; Chen L; Frank J et al.
Source: Self-asserted source
Kim Brügger via Europe PubMed Central

Four newly isolated fuselloviruses from extreme geothermal environments reveal unusual morphologies and a possible interviral recombination mechanism.

Environmental microbiology
2009-07 | Journal article
DOI: 10.1111/j.1462-2920.2009.02009.x
PMID: 19638177
Contributors: Redder P; Peng X; Brügger K; Shah SA; Roesch F; Greve B; She Q; Schleper C; Forterre P; Garrett RA et al.
Source: Self-asserted source
Kim Brügger via Europe PubMed Central

CRISPR families of the crenarchaeal genus Sulfolobus: bidirectional transcription and dynamic properties.

Molecular microbiology
2009-02 | Journal article
DOI: 10.1111/j.1365-2958.2009.06641.x
PMID: 19239620
Contributors: Lillestøl RK; Shah SA; Brügger K; Redder P; Phan H; Christiansen J; Garrett RA
Source: Self-asserted source
Kim Brügger via Europe PubMed Central

Structure of the acidianus filamentous virus 3 and comparative genomics of related archaeal lipothrixviruses.

Journal of virology
2007-10 | Journal article
DOI: 10.1128/jvi.01410-07
PMID: 17942536
PMC: PMC2224351
Contributors: Vestergaard G; Aramayo R; Basta T; Häring M; Peng X; Brügger K; Chen L; Rachel R; Boisset N; Garrett RA et al.
Source: Self-asserted source
Kim Brügger via Europe PubMed Central

The genome of Hyperthermus butylicus: a sulfur-reducing, peptide fermenting, neutrophilic Crenarchaeote growing up to 108 degrees C.

Archaea (Vancouver, B.C.)
2007-05 | Journal article
DOI: 10.1155/2007/745987
PMID: 17350933
PMC: PMC2686385
Contributors: Brügger K; Chen L; Stark M; Zibat A; Redder P; Ruepp A; Awayez M; She Q; Garrett RA; Klenk HP
Source: Self-asserted source
Kim Brügger via Europe PubMed Central

The Sulfolobus database.

Nucleic acids research
2006-11 | Journal article
DOI: 10.1093/nar/gkl847
PMID: 17088281
PMC: PMC1669736
Contributors: Brügger K
Source: Self-asserted source
Kim Brügger via Europe PubMed Central

A putative viral defence mechanism in archaeal cells.

Archaea (Vancouver, B.C.)
2006-08 | Journal article
DOI: 10.1155/2006/542818
PMID: 16877322
PMC: PMC2685585
Contributors: Lillestøl RK; Redder P; Garrett RA; Brügger K
Source: Self-asserted source
Kim Brügger via Europe PubMed Central

The genome of Sulfolobus acidocaldarius, a model organism of the Crenarchaeota.

Journal of bacteriology
2005-07 | Journal article
DOI: 10.1128/jb.187.14.4992-4999.2005
PMID: 15995215
PMC: PMC1169522
Contributors: Chen L; Brügger K; Skovgaard M; Redder P; She Q; Torarinsson E; Greve B; Awayez M; Zibat A; Klenk HP et al.
Source: Self-asserted source
Kim Brügger via Europe PubMed Central

Structure and genome organization of AFV2, a novel archaeal lipothrixvirus with unusual terminal and core structures.

Journal of bacteriology
2005-06 | Journal article
DOI: 10.1128/jb.187.11.3855-3858.2005
PMID: 15901711
PMC: PMC1112056
Contributors: Häring M; Vestergaard G; Brügger K; Rachel R; Garrett RA; Prangishvili D
Source: Self-asserted source
Kim Brügger via Europe PubMed Central

Novel RepA-MCM proteins encoded in plasmids pTAU4, pORA1 and pTIK4 from Sulfolobus neozealandicus.

Archaea (Vancouver, B.C.)
2005-05 | Journal article
DOI: 10.1155/2005/159218
PMID: 15876565
PMC: PMC2685554
Contributors: Greve B; Jensen S; Phan H; Brügger K; Zillig W; She Q; Garrett RA
Source: Self-asserted source
Kim Brügger via Europe PubMed Central

Identification of novel non-coding RNAs as potential antisense regulators in the archaeon Sulfolobus solfataricus.

Molecular microbiology
2005-01 | Journal article
DOI: 10.1111/j.1365-2958.2004.04428.x
PMID: 15659164
Contributors: Tang TH; Polacek N; Zywicki M; Huber H; Brugger K; Garrett R; Bachellerie JP; Hüttenhofer A
Source: Self-asserted source
Kim Brügger via Europe PubMed Central

Genomic comparison of archaeal conjugative plasmids from Sulfolobus.

Archaea (Vancouver, B.C.)
2004-10 | Journal article
DOI: 10.1155/2004/151926
PMID: 15810432
PMC: PMC2685578
Contributors: Greve B; Jensen S; Brügger K; Zillig W; Garrett RA
Source: Self-asserted source
Kim Brügger via Europe PubMed Central

Morphology and genome organization of the virus PSV of the hyperthermophilic archaeal genera Pyrobaculum and Thermoproteus: a novel virus family, the Globuloviridae.

Virology
2004-06 | Journal article
DOI: 10.1016/j.virol.2004.03.002
PMID: 15193919
Contributors: Häring M; Peng X; Brügger K; Rachel R; Stetter KO; Garrett RA; Prangishvili D
Source: Self-asserted source
Kim Brügger via Europe PubMed Central

Shuffling of Sulfolobus genomes by autonomous and non-autonomous mobile elements.

Biochemical Society transactions
2004-04 | Journal article
DOI: 10.1042/bst0320179
PMID: 15046567
Contributors: Brügger K; Torarinsson E; Redder P; Chen L; Garrett RA
Source: Self-asserted source
Kim Brügger via Europe PubMed Central

MUTAGEN: multi-user tool for annotating genomes.

Bioinformatics (Oxford, England)
2003-12 | Journal article
DOI: 10.1093/bioinformatics/btg336
PMID: 14668237
Contributors: Brügger K; Redder P; Skovgaard M
Source: Self-asserted source
Kim Brügger via Europe PubMed Central

Genus-specific protein binding to the large clusters of DNA repeats (short regularly spaced repeats) present in Sulfolobus genomes.

Journal of bacteriology
2003-04 | Journal article
DOI: 10.1128/jb.185.8.2410-2417.2003
PMID: 12670964
PMC: PMC152625
Contributors: Peng X; Brügger K; Shen B; Chen L; She Q; Garrett RA
Source: Self-asserted source
Kim Brügger via Europe PubMed Central

Archaeal integrative genetic elements and their impact on genome evolution.

Research in microbiology
2002-07 | Journal article
DOI: 10.1016/s0923-2508(02)01331-1
PMID: 12234006
Contributors: She Q; Brügger K; Chen L
Source: Self-asserted source
Kim Brügger via Europe PubMed Central

Mobile elements in archaeal genomes.

FEMS microbiology letters
2002-01 | Journal article
DOI: 10.1111/j.1574-6968.2002.tb10999.x
PMID: 11814653
Contributors: Brügger K; Redder P; She Q; Confalonieri F; Zivanovic Y; Garrett RA
Source: Self-asserted source
Kim Brügger via Europe PubMed Central

Sequences and replication of genomes of the archaeal rudiviruses SIRV1 and SIRV2: relationships to the archaeal lipothrixvirus SIFV and some eukaryal viruses.

Virology
2001-12 | Journal article
DOI: 10.1006/viro.2001.1190
PMID: 11878892
Contributors: Peng X; Blum H; She Q; Mallok S; Brügger K; Garrett RA; Zillig W; Prangishvili D
Source: Self-asserted source
Kim Brügger via Europe PubMed Central
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