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Biography

My research interest has been focused on inflammation in the context of atherosclerosis and neurodegenerative disease including multiple sclerosis and CADASIL. Throughout my career to date, I have had the opportunity to carry out research in state-of-the-art facilities in Ireland, UK and USA. I have led several research projects working on identification of novel targets in atherosclerosis, development of immunomodulatory therapeutics and biomarkers for chronic inflammatory disease. To date my research has led to a total of 7 publications with 4 currently in submission/review phase. I am a highly motivated scientist, with a keen interest in inflammatory disease. My academic career has helped me to develop a strong scientific grounding while also enhancing my organizational, problem solving and teamwork skills. I enjoy collaborating with others and have experience in presenting scientific information, creating new hypotheses and implementing solutions. This fellowship will allow me to progress to achieve my personal aim which is to develop a variety of skills, knowledge and experience to allow me to contribute to the development of therapies and biomarkers for neuroinflammatory disease.

Activities

Employment (3)

Icahn School of Medicine at Mount Sinai Department of Medicine: New York, NY, US

2022-06-20 to present | Postdoctoral Fellow (Neurology)
Employment
Source: Self-asserted source
Stephen Fitzsimons

Royal College of Surgeons in Ireland: Dublin, Dublin, IE

2021-01-01 to 2022-05-31 | Postdoctoral Fellow (SChool of Pharmacy and Biomolecular Science)
Employment
Source: Self-asserted source
Stephen Fitzsimons

University College Dublin: Dublin, Dublin, IE

2019-10-01 to 2020-12-31 | Postdoctoral Fellow (School of Biomolecular and Biomedical Science)
Employment
Source: Self-asserted source
Stephen Fitzsimons

Education and qualifications (2)

University College Dublin: Dublin, Dublin, IE

2015-10-01 to 2019-09-30 | Doctor of Philosophy Degree (PhD) (School of Biomolecular and Biomedical Science)
Education
Source: Self-asserted source
Stephen Fitzsimons

University College Dublin: Dublin, Dublin, IE

2011-09-01 to 2015-05-31 | Bachelor of Science (Honours) in Pharmacology (School of Biomolecular and Biomedical Science)
Education
Source: Self-asserted source
Stephen Fitzsimons

Works (9)

A comparative analysis of extracellular vesicles (EVs) from human and feline plasma

Scientific Reports
2022-12 | Journal article
Part of ISSN: 2045-2322
Contributors: Stephen Fitzsimons
Source: Self-asserted source
Stephen Fitzsimons

Enhancing arginase 2 expression using target site blockers as a strategy to modulate macrophage phenotype

Molecular Therapy - Nucleic Acids
2022-09 | Journal article
Part of ISSN: 2162-2531
Contributors: Stephen Fitzsimons
Source: Self-asserted source
Stephen Fitzsimons

Carbon Dioxide Sensing by Immune Cells Occurs through Carbonic Anhydrase 2–Dependent Changes in Intracellular pH

The Journal of Immunology
2022-05-15 | Journal article
Part of ISSN: 0022-1767
Part of ISSN: 1550-6606
Contributors: Stephen Fitzsimons
Source: Self-asserted source
Stephen Fitzsimons

Extracellular vesicles from monocyte/platelet aggregates modulate human atherosclerotic plaque reactivity

Journal of Extracellular Vesicles
2021-04 | Journal article
Part of ISSN: 2001-3078
Part of ISSN: 2001-3078
Contributors: Stephen Fitzsimons
Source: Self-asserted source
Stephen Fitzsimons

microRNA-155 Is Decreased During Atherosclerosis Regression and Is Increased in Urinary Extracellular Vesicles During Atherosclerosis Progression

Frontiers in Immunology
2020-12-17 | Journal article
Part of ISSN: 1664-3224
Contributors: Stephen Fitzsimons
Source: Self-asserted source
Stephen Fitzsimons

Different monocyte phenotypes result in proresolving macrophages in conjugated linoleic acid‐induced attenuated progression and regression of atherosclerosis

The FASEB Journal
2019-10 | Journal article
Part of ISSN: 0892-6638
Part of ISSN: 1530-6860
Contributors: Stephen Fitzsimons
Source: Self-asserted source
Stephen Fitzsimons

ApoE elevation is associated with the persistence of psychotic experiences from age 12 to age 18: Evidence from the ALSPAC birth cohort

Schizophrenia Research
2019-07 | Journal article
Part of ISSN: 0920-9964
Contributors: Stephen Fitzsimons
Source: Self-asserted source
Stephen Fitzsimons

miR-155 in the Resolution of Atherosclerosis

Frontiers in Pharmacology
2019-05-14 | Journal article
Part of ISSN: 1663-9812
Contributors: Stephen Fitzsimons
Source: Self-asserted source
Stephen Fitzsimons

Atheroprotective effects of conjugated linoleic acid

British Journal of Clinical Pharmacology
2017-01 | Journal article
Part of ISSN: 0306-5251
Contributors: Stephen Fitzsimons
Source: Self-asserted source
Stephen Fitzsimons