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Employment (5)

Inserm: Paris, FR

2021 to present | PI (Istem)
Employment
Source: Self-asserted source
Nicolas Tricaud

Inserm ADR Languedoc-Roussillon: Montpellier, FR

2021 to 2022 | PI (IRMB)
Employment
Source: Self-asserted source
Nicolas Tricaud

Délégation Régionale Occitanie Méditerranée: Montpellier, FR

2010 to 2021 | PI (Institut des Neurosciences de Montpellier)
Employment
Source: Self-asserted source
Nicolas Tricaud

ETH Zurich: Zurich, CH

2005 to 2010 | Senior Scientist (Institut of Molecular Health Sciences Suter lab)
Employment
Source: Self-asserted source
Nicolas Tricaud

Memorial Sloan Kettering Cancer Center: New York, US

2000 to 2005 | Scientist (Sloan Kettering Institute Rutishauser lab)
Employment
Source: Self-asserted source
Nicolas Tricaud

Education and qualifications (2)

University of Montpellier: Montpellier, FR

2011 to present | Habilitation à diriger des recherches (Institut des Neurosciences de Montpellier)
Education
Source: Self-asserted source
Nicolas Tricaud

Université de la Mediterranée: Marseille, FR

1995 to 2000 | Ph. D.
Education
Source: Self-asserted source
Nicolas Tricaud

Funding (3)

Roles of mitochondria in healthy and diseased myelin

2013-04-01 to 2018-03-31 | Grant
European Research Council (Brussels, BE)
GRANT_NUMBER: 311610
Source: Self-asserted source
Nicolas Tricaud via DimensionsWizard

Roles of polarity genes in myelination

2008-06-01 to 2011-12-31 | Grant
Swiss National Science Foundation (Bern, CH)
GRANT_NUMBER: 120138
Source: Self-asserted source
Nicolas Tricaud via DimensionsWizard

Mouse models for human dieases

2008-06-01 to 2008-11-30 | Grant
Swiss National Science Foundation (Bern, CH)
GRANT_NUMBER: 121422
Source: Self-asserted source
Nicolas Tricaud via DimensionsWizard

Works (41)

The <i>Hexokinase 1</i> 5'-UTR Mutation in Charcot-Marie-Tooth 4G Disease Alters Hexokinase 1 Binding to Voltage-Dependent Anion Channel-1 and Leads to Dysfunctional Mitochondrial Calcium Buffering

International journal of molecular sciences
2024 | Journal article
Part of ISSN: 1422-0067
Contributors: Ceprian, Maria; Juntas-Morales, Raul; Campbell, Graham; Walther-Louvier, Ulrike; Rivier, François; Camu, William; Esselin, Florence; Echaniz-Laguna, Andoni; Stojkovic, Tanya; Bouhour, Françoise et al.
Source: Self-asserted source
Nicolas Tricaud

Mapping the N-Terminal Hexokinase-I Binding Site onto Voltage-Dependent Anion Channel-1 To Block Peripheral Nerve Demyelination

Journal of medicinal chemistry
2022 | Journal article
Part of ISSN: 0022-2623
Contributors: Gautier, Benoit; Forêt Jacquard, Mélanie; Guelfi, Sophie; Abbou, Scarlette; Gonzalez, Elisa; Berthelot, Jade; Boukhaddaoui, Hassan; Lebrun, Aurélien; Legrand, Baptiste; Tricaud, Nicolas et al.
Source: Self-asserted source
Nicolas Tricaud

Physiology of PNS axons relies on glycolytic metabolism in myelinating Schwann cells

PloS one
2022 | Journal article
Part of ISSN: 1932-6203
Contributors: Deck, Marie; Van Hameren, Gerben; Campbell, Graham; Bernard-Marissal, Nathalie; Devaux, Jérôme; Berthelot, Jade; Lattard, Alise; Médard, Jean-Jacques; Gautier, Benoît; Guelfi, Sophie et al.
Source: Self-asserted source
Nicolas Tricaud

Traumatic and Diabetic Schwann Cell Demyelination Is Triggered by a Transient Mitochondrial Calcium Release through Voltage Dependent Anion Channel 1

Biomedicines
2022 | Journal article
Part of ISSN: 2227-9059
Contributors: Tricaud, Nicolas; Gautier, Benoit; Berthelot, Jade; Gonzalez, Sergio; Van Hameren, Gerben
Source: Self-asserted source
Nicolas Tricaud

AAV2/9-mediated silencing of PMP22 prevents the development of pathological features in a rat model of Charcot-Marie-Tooth disease 1 A

Nature communications
2021 | Journal article
Part of ISSN: 2041-1723
Contributors: Gautier, Benoit; Hajjar, Helene; Soares, Sylvia; Berthelot, Jade; Deck, Marie; Abbou, Scarlette; Campbell, Graham; Ceprian, Maria; Gonzalez, Sergio; Fovet, Claire-Maëlle et al.
Source: Self-asserted source
Nicolas Tricaud

Dual imaging of dendritic spines and mitochondria <i>in vivo</i> reveals hotspots of plasticity and metabolic adaptation to stress

Neurobiology of stress
2021 | Journal article
Part of ISSN: 2352-2895
Contributors: Dromard, Yann; Arango-Lievano, Margarita; Fontanaud, Pierre; Tricaud, Nicolas; Jeanneteau, Freddy
Source: Self-asserted source
Nicolas Tricaud

Physiology of PNS axons relies on glycolytic metabolism in myelinating Schwann cells

bioRxiv
2020 | Journal article
Contributors: Deck, Marie; Van Hameren, Gerben; Campbell, Graham; Bernard-Marissal, Nathalie; Devaux, Jérôme; Berthelot, Jade; Lattard, Alise; Médard, Jean-Jacques; Gautier, Benoît; Quintana, Patrice et al.
Source: Self-asserted source
Nicolas Tricaud

Long term AAV2/9-mediated silencing of PMP22 prevents CMT1A disease in rats and validates skin biomarkers as treatment outcome measure

BioRxiv
2020-01-30 | Journal article
Source: Self-asserted source
Nicolas Tricaud

Altered interplay between endoplasmic reticulum and mitochondria in Charcot-Marie-Tooth type 2A neuropathy

Proceedings of the National Academy of Sciences of the United States of America
2019 | Journal article
Source: Self-asserted source
Nicolas Tricaud

Schwann cell demyelination is triggered by a transient mitochondrial calcium release through Voltage Dependent Anion Channel 1

BioRxiv
2019 | Journal article
Source: Self-asserted source
Nicolas Tricaud

The conceptual introduction of the "demyelinating Schwann cell" in peripheral demyelinating neuropathies

Glia
2019 | Journal article
Source: Self-asserted source
Nicolas Tricaud

In vivo real-time dynamics of ATP and ROS production in axonal mitochondria show decoupling in mouse models of peripheral neuropathies

Acta Neuropathologica Communications
2019-12 | Journal article
Part of ISSN: 2051-5960
Source: Self-asserted source
Nicolas Tricaud

LKB1 specifies neural crest cell fates through pyruvate-alanine cycling

Science Advances
2019-07 | Journal article
Part of ISSN: 2375-2548
Source: Self-asserted source
Nicolas Tricaud

CMT disease 2A and demyelination decouple ATP and ROS production by axonal mitochondria

BioRxiv
2018 | Journal article
Source: Self-asserted source
Nicolas Tricaud

In Vivo Introduction of Transgenes into Mouse Sciatic Nerve Cells Using Viral Vectors

Myelin
2018 | Other
Part of ISBN: 9781493978618
Part of ISSN: 1064-3745
Contributors: Gerben Van Hameren; Sergio Gonzalez; Ruani N. Fernando; Claire Perrin-Tricaud; Nicolas Tricaud
Source: Self-asserted source
Nicolas Tricaud via Crossref Metadata Search

Label-free non-linear microscopy to measure myelin outcome in a rodent model of Charcot-Marie-Tooth diseases

Journal of Biophotonics
2018-08-09 | Journal article
Part of ISSN: 1864-063X
Contributors: H Hajjar; H Boukhaddaoui; A Rizgui; C Sar; J Berthelot; C Perrin-Tricaud; H Rigneault; N Tricaud
Source: Self-asserted source
Nicolas Tricaud via Crossref Metadata Search

Myelinating Schwann Cell Polarity and Mechanically-Driven Myelin Sheath Elongation

Frontiers in Cellular Neuroscience
2018-01-05 | Journal article
Part of ISSN: 1662-5102
Contributors: Nicolas Tricaud
Source: Self-asserted source
Nicolas Tricaud via Crossref Metadata Search

Wallerian demyelination: chronicle of a cellular cataclysm

Cellular and Molecular Life Sciences
2017-11-09 | Journal article
Contributors: Nicolas Tricaud; Hwan Tae Park
Source: check_circle
Crossref

A Combination of Ex vivo Diffusion MRI and Multiphoton to Study Microglia/Monocytes Alterations after Spinal Cord Injury

Frontiers in Aging Neuroscience
2017-07 | Journal article
Part of ISSN: 1663-4365
Contributors: Harun N. Noristani; Hassan Boukhaddaoui; Guillaume Saint-Martin; Pauline Auzer; Rahima Sidiboulenouar; Nicolas Lonjon; Eric Alibert; Nicolas Tricaud; Christophe Goze-Bac; Christophe Coillot et al.
Source: Self-asserted source
Nicolas Tricaud via Crossref Metadata Search

Optimal myelin elongation relies on YAP activation by axonal growth and inhibition by Crb3/Hippo pathway

Nature Communications
2016-07-20 | Journal article
Contributors: Ruani N. Fernando; Laurent Cotter; Claire Perrin-Tricaud; Jade Berthelot; Sylvain Bartolami; Jorge A. Pereira; Sergio Gonzalez; Ueli Suter; Nicolas Tricaud
Source: check_circle
Crossref

Assembly of juxtaparanodes in myelinating DRG culture: Differential clustering of the Kv1/Caspr2 complex and scaffolding protein 4.1B.

2016-05 | Journal article
Contributors: Hivert B; Pinatel D; Labasque M; Tricaud N; Goutebroze L; Faivre-Sarrailh C
Source: Self-asserted source
Nicolas Tricaud via Europe PubMed Central

In vivo time-lapse imaging of mitochondria in healthy and diseased peripheral myelin sheath.

2015-07 | Journal article
Contributors: Gonzalez S; Fernando R; Berthelot J; Perrin-Tricaud C; Sarzi E; Chrast R; Lenaers G; Tricaud N
Source: Self-asserted source
Nicolas Tricaud via Europe PubMed Central

Distribution of monocarboxylate transporters in the peripheral nervous system suggests putative roles in lactate shuttling and myelination.

2015-03 | Journal article
Contributors: Domènech-Estévez E; Baloui H; Repond C; Rosafio K; Médard JJ; Tricaud N; Pellerin L; Chrast R
Source: Self-asserted source
Nicolas Tricaud via Europe PubMed Central

Giant scaffolding protein AHNAK1 interacts with β-dystroglycan and controls motility and mechanical properties of Schwann cells.

2014-09 | Journal article
Contributors: von Boxberg Y; Soares S; Féréol S; Fodil R; Bartolami S; Taxi J; Tricaud N; Nothias F
Source: Self-asserted source
Nicolas Tricaud via Europe PubMed Central

In vivo introduction of transgenes into mouse sciatic nerve cells in situ using viral vectors.

2014-05 | Journal article
Contributors: Gonzalez S; Fernando RN; Perrin-Tricaud C; Tricaud N
Source: Self-asserted source
Nicolas Tricaud via Europe PubMed Central

[More myelin is not necessarily good].

2012-04 | Journal article
Contributors: Bartolami S; Tricaud N
Source: Self-asserted source
Nicolas Tricaud via Europe PubMed Central

HDAC1 and HDAC2 control the transcriptional program of myelination and the survival of Schwann cells.

2011-04 | Journal article
Contributors: Jacob C; Christen CN; Pereira JA; Somandin C; Baggiolini A; Lötscher P; Ozçelik M; Tricaud N; Meijer D; Yamaguchi T et al.
Source: Self-asserted source
Nicolas Tricaud via Europe PubMed Central

Dlg1-PTEN interaction regulates myelin thickness to prevent damaging peripheral nerve overmyelination.

2010-06 | Journal article
Contributors: Cotter L; Ozçelik M; Jacob C; Pereira JA; Locher V; Baumann R; Relvas JB; Suter U; Tricaud N
Source: Self-asserted source
Nicolas Tricaud via Europe PubMed Central

Pals1 is a major regulator of the epithelial-like polarization and the extension of the myelin sheath in peripheral nerves.

2010-03 | Journal article
Contributors: Ozçelik M; Cotter L; Jacob C; Pereira JA; Relvas JB; Suter U; Tricaud N
Source: Self-asserted source
Nicolas Tricaud via Europe PubMed Central

SH3TC2/KIAA1985 protein is required for proper myelination and the integrity of the node of Ranvier in the peripheral nervous system.

2009-10 | Journal article
Contributors: Arnaud E; Zenker J; de Preux Charles AS; Stendel C; Roos A; Médard JJ; Tricaud N; Kleine H; Luscher B; Weis J et al.
Source: Self-asserted source
Nicolas Tricaud via Europe PubMed Central

Integrin-linked kinase is required for radial sorting of axons and Schwann cell remyelination in the peripheral nervous system.

2009-04 | Journal article
Contributors: Pereira JA; Benninger Y; Baumann R; Gonçalves AF; Ozçelik M; Thurnherr T; Tricaud N; Meijer D; Fässler R; Suter U et al.
Source: Self-asserted source
Nicolas Tricaud via Europe PubMed Central

P120 catenin is required for thickening of Schwann cell myelin.

2007-05 | Journal article
Contributors: Perrin-Tricaud C; Rutishauser U; Tricaud N
Source: Self-asserted source
Nicolas Tricaud via Europe PubMed Central

Adherens junctions in myelinating Schwann cells stabilize Schmidt-Lanterman incisures via recruitment of p120 catenin to E-cadherin.

2005-03 | Journal article
Contributors: Tricaud N; Perrin-Tricaud C; Brusés JL; Rutishauser U
Source: Self-asserted source
Nicolas Tricaud via Europe PubMed Central

Interaction of the Nav1.2a subunit of the voltage-dependent sodium channel with nodal ankyrinG. In vitro mapping of the interacting domains and association in synaptosomes.

2002-08 | Journal article
Contributors: Bouzidi M; Tricaud N; Giraud P; Kordeli E; Caillol G; Deleuze C; Couraud F; Alcaraz G
Source: Self-asserted source
Nicolas Tricaud via Europe PubMed Central

On the kaliotoxin and dendrotoxin binding sites on rat brain synaptosomes.

2000-12 | Journal article
Contributors: Tricaud N; Marchot P; Martin-Eauclaire MF
Source: Self-asserted source
Nicolas Tricaud via Europe PubMed Central

Direct interaction between synaptotagmin and the intracellular loop I-II of neuronal voltage-sensitive sodium channels.

2000-03 | Journal article
Contributors: Sampo B; Tricaud N; Leveque C; Seagar M; Couraud F; Dargent B
Source: Self-asserted source
Nicolas Tricaud via Europe PubMed Central

Assembly intracellular targeting and cell surface expression of the human N-methyl-D-aspartate receptor subunits NR1a and NR2A in transfected cells.

1998 | Journal article
PMID: 9849671
Contributors: McIlhinney RA; Le Bourdellès B; Molnár E; Tricaud N; Streit P; Whiting PJ
Source: Self-asserted source
Nicolas Tricaud via Europe PubMed Central

Identification of lectin-purified neural glycoproteins, GPs 180, 116, and 110, with NMDA and AMPA receptor subunits: conservation of glycosylation at the synapse.

1998-06 | Journal article
PMID: 9603226
Contributors: Clark RA; Gurd JW; Bissoon N; Tricaud N; Molnar E; Zamze SE; Dwek RA; McIlhinney RA; Wing DR
Source: Self-asserted source
Nicolas Tricaud via Europe PubMed Central

Down-regulation of voltage-dependent sodium channels coincides with a low expression of alphabeta1 subunit complexes.

1997-11 | Journal article
PMID: 9427516
Contributors: Alcaraz G; Sampo B; Tricaud N; Giraud P; Martin-Eauclaire MF; Couraud F; Dargent B
Source: Self-asserted source
Nicolas Tricaud via Europe PubMed Central

Activation of voltage-dependent sodium channels in cultured cerebellar poffule cells induces neurotoxicity that is not mediated by glutamate release.

1996-07 | Journal article
PMID: 8783243
Contributors: Dargent B; Arsac C; Tricaud N; Couraud F
Source: Self-asserted source
Nicolas Tricaud via Europe PubMed Central

Channel activators reduce the expression of sodium channel alpha-subunit mRNA in developing neurons.

1996-04 | Journal article
PMID: 8738142
Contributors: Lara A; Dargent B; Julien F; Alcaraz G; Tricaud N; Couraud F; Jover E
Source: Self-asserted source
Nicolas Tricaud via Europe PubMed Central

Peer review (2 reviews for 1 publication/grant)

Review activity for Molecular therapy. (2)