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Works (21)

Housing mice near vs. below thermoneutrality affects drug-induced weight loss but does not improve prediction of efficacy in humans.

Cell reports
2024-07-25 | Journal article
DOI: 10.1016/j.celrep.2024.114501
PMID: 39067024
PMC: PMC11380917
Contributors: Jacobsen JM; Petersen N; Torz L; Gerstenberg MK; Pedersen K; Østergaard S; Wulff BS; Andersen B; Raun K; Christoffersen BØ et al.
Source: Self-asserted source
Linu M. John

NN1213 – A Potent, Long-Acting, and Selective Analog of Human Amylin

Journal of Medicinal Chemistry
2024-07-25 | Journal article
DOI: 10.1021/acs.jmedchem.4c00022
Contributors: Kirsten Dahl; Kirsten Raun; Jakob Lerche Hansen; Christian Poulsen; Charlotta D. de la Cour; Trine Ryberg Clausen; Ann Maria Kruse Hansen; Linu M. John; Annette Plesner; Gao Sun et al.
Source: check_circle
Crossref

Body weight lowering effect of glucose-dependent insulinotropic polypeptide and glucagon-like peptide receptor agonists is more efficient in RAMP1/3 KO than in WT mice.

European journal of pharmacology
2023-07-14 | Journal article
DOI: 10.1016/j.ejphar.2023.175912
PMID: 37454968
Contributors: Leuthardt AS; Boyle CN; Raun K; Lutz TA; John LM; Christelle Le Foll
Source: Self-asserted source
Linu M. John

Housing-temperature reveals energy intake counter-balances energy expenditure in normal-weight, but not diet-induced obese, male mice.

Communications biology
2022-09-10 | Journal article
DOI: 10.1038/s42003-022-03895-8
PMID: 36088386
PMC: PMC9464191
Contributors: Linu M. John
Source: Self-asserted source
Linu M. John

Beyond appetite regulation: Targeting energy expenditure, fat oxidation, and lean mass preservation for sustainable weight loss.

Obesity (Silver Spring, Md.)
2022-04-01 | Journal article
DOI: 10.1002/oby.23374
PMID: 35333444
Source: Self-asserted source
Linu M. John

NPFF Decreases Activity of Human Arcuate NPY Neurons: A Study in Embryonic-Stem-Cell-Derived Model.

International journal of molecular sciences
2022-03-17 | Journal article
DOI: 10.3390/ijms23063260
PMID: 35328681
PMC: PMC8948797
Source: Self-asserted source
Linu M. John

In vitro prediction of in vivo pseudo-allergenic response via MRGPRX2.

Journal of immunotoxicology
2021-12-01 | Journal article
DOI: 10.1080/1547691x.2021.1877375
PMID: 33570451
Source: Self-asserted source
Linu M. John

A selective role for receptor activity-modifying proteins in subchronic action of the amylin selective receptor agonist NN1213 compared with salmon calcitonin on body weight and food intake in male mice.

The European journal of neuroscience
2021-07-09 | Journal article
DOI: 10.1111/ejn.15376
PMID: 34189795
PMC: PMC8457108
Source: Self-asserted source
Linu M. John

FGF21 regulates hepatic metabolic pathways to improve steatosis and inflammation.

Endocrine connections
2020-07-01 | Journal article
DOI: 10.1530/ec-20-0152
PMID: 32688339
Source: Self-asserted source
Linu M. John

Central control of energy balance by amylin and calcitonin receptor agonists and their potential for treatment of metabolic diseases.

Basic & clinical pharmacology & toxicology
2020-05-04 | Journal article
DOI: 10.1111/bcpt.13427
PMID: 32363722
Source: Self-asserted source
Linu M. John

Semaglutide lowers body weight in rodents via distributed neural pathways.

JCI insight
2020-03-26 | Journal article
DOI: 10.1172/jci.insight.133429
PMID: 32213703
PMC: PMC7213778
Source: Self-asserted source
Linu M. John

Salmon calcitonin distributes into the arcuate nucleus to a subset of NPY neurons in mice.

Neuropharmacology
2020-02-05 | Journal article
DOI: 10.1016/j.neuropharm.2020.107987
PMID: 32035146
Source: Self-asserted source
Linu M. John

Quantitative whole-brain 3D imaging of tyrosine hydroxylase-labeled neuron architecture in the mouse MPTP model of Parkinson's disease.

Disease models & mechanisms
2019-11-22 | Journal article
DOI: 10.1242/dmm.042200
PMID: 31704726
PMC: PMC6899010
Source: Self-asserted source
Linu M. John

GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand.

Nature medicine
2017-08-28 | Journal article
DOI: 10.1038/nm.4394
PMID: 28846099
Source: Self-asserted source
Linu M. John

Nontranscriptional modulation of intracellular Ca2+ signaling by ligand stimulated thyroid hormone receptor.

The Journal of cell biology
2004-11-29 | Journal article
DOI: 10.1083/jcb.200409011
PMID: 15569710
PMC: PMC2172460
Source: Self-asserted source
Linu M. John

Fibroblast growth factor 19 increases metabolic rate and reverses dietary and leptin-deficient diabetes.

Endocrinology
2004-02-19 | Journal article
DOI: 10.1210/en.2003-1671
PMID: 14976145
Source: Self-asserted source
Linu M. John

Calnexin and Calreticulin, ER Associated Modulators of Calcium Transport in the ER.

Calreticulin. 2nd Edition
2003 | Book chapter
Source: Self-asserted source
Linu M. John

Transgenic mice expressing human fibroblast growth factor-19 display increased metabolic rate and decreased adiposity.

Endocrinology
2002-05-01 | Journal article
DOI: 10.1210/endo.143.5.8850
PMID: 11956156
Source: Self-asserted source
Linu M. John

Control of IP(3)-mediated Ca2+ puffs in Xenopus laevis oocytes by the Ca2+-binding protein parvalbumin.

The Journal of physiology
2001-08-01 | Journal article
DOI: 10.1111/j.1469-7793.2001.t01-2-00003.x
PMID: 11507154
Source: Self-asserted source
Linu M. John

Differential modulation of SERCA2 isoforms by calreticulin.

The Journal of Cell Biology
1998-08-01 | Journal article
DOI: 10.1083/jcb.142.4.963
PMID: 9722609
PMC: PMC2132884
Source: Self-asserted source
Linu M. John

Ca2+ wave dispersion and spiral wave entrainment in Xenopus laevis oocytes overexpressing Ca2+ ATPases.

Biophysical chemistry
1998-05-01 | Journal article
DOI: 10.1016/s0301-4622(98)00128-8
PMID: 9652090
Source: Self-asserted source
Linu M. John
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