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Activities

Employment (1)

North Carolina State University North Carolina Agricultural Research Service: Raleigh, NC, US

2011-08-16 to present | Research Assistant Professor (Molecular and Structural Biochemistry)
Employment
Source: Self-asserted source
Paul Swartz

Education and qualifications (3)

Washington State University: Pullman, WA, US

1996 to present | Ph.D. (Biochemistry)
Education
Source: Self-asserted source
Paul Swartz

Oklahoma State Universty: Stillwater, OK, US

1987 to present | MS (Biochemistry)
Education
Source: Self-asserted source
Paul Swartz

Oklahoma State University: Stillwater, OK, US

1985 to present | BS (Biochemistry)
Education
Source: Self-asserted source
Paul Swartz

Professional activities (4)

Phi Lambda Upsilon: Stillwater, OK, US

Membership
Source: Self-asserted source
Paul Swartz

Gamma Sigma Delta: Stillwater, OK, US

Membership
Source: Self-asserted source
Paul Swartz

American Crystallographic Association: Buffalo, New York, US

2012 to present
Membership
Source: Self-asserted source
Paul Swartz

American Chemical Society: Washington, DC, US

1985 to present
Membership
Source: Self-asserted source
Paul Swartz

Funding (1)

Mining Multiple Solvent Crystal Structures for Properties of Protein Binding Sites

2008-08 to 2012-04 | Award
National Science Foundation (VA, VA, US)
Part of GRANT_NUMBER:

0818678

Source: Self-asserted source
Paul Swartz

Works (28)

DRoP: Automated detection of conserved solvent-binding sites on proteins

Proteins
2020 | Journal article
Source: Self-asserted source
Paul Swartz

Resurrection of ancestral effector caspases identifies novel networks for evolution of substrate specificity

Source: Self-asserted source
Paul Swartz

Resurrection of ancestral effector caspases identifies novel networks for evolution of substrate specificity

The Biochemical journal
2019 | Journal article
Source: Self-asserted source
Paul Swartz

Modifications to a common phosphorylation network provide individualized control in caspases

The Journal of biological chemistry
2018 | Journal article
Source: Self-asserted source
Paul Swartz

Selective tuning of activity in a multifunctional enzyme as revealed in the F21W mutant of dehaloperoxidase B from Amphitrite ornata

Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry
2018 | Journal article
Source: Self-asserted source
Paul Swartz

Crystallization of a fungal lytic polysaccharide monooxygenase expressed from glycoengineered Pichia pastoris for X-ray and neutron diffraction

Acta crystallographica. Section F, Structural biology communications
2017 | Journal article
Source: Self-asserted source
Paul Swartz

Phage display and structural studies reveal plasticity in substrate specificity of caspase-3a from zebrafish

Protein science : a publication of the Protein Society
2016 | Journal article
Source: Self-asserted source
Paul Swartz

Tunable allosteric library of caspase-3 identifies coupling between conserved water molecules and conformational selection

Proceedings of the National Academy of Sciences of the United States of America
2016 | Journal article
Source: Self-asserted source
Paul Swartz

Crystallization and preliminary X-ray diffraction analysis of Hypocrea jecorina Cel7A in two new crystal forms

Acta crystallographica. Section F, Structural biology communications
2014 | Journal article
Source: Self-asserted source
Paul Swartz

DRoP: a water analysis program identifies Ras-GTP-specific pathway of communication between membrane-interacting regions and the active site

Journal of molecular biology
2014 | Journal article
Source: Self-asserted source
Paul Swartz

Modifying caspase-3 activity by altering allosteric networks

Biochemistry
2014 | Journal article
Source: Self-asserted source
Paul Swartz

Lengthening the intersubunit linker of procaspase 3 leads to constitutive activation

Biochemistry
2013 | Journal article
Source: Self-asserted source
Paul Swartz

The role of T56 in controlling the flexibility of the distal histidine in dehaloperoxidase-hemoglobin from Amphitrite ornata

Biochimica et biophysica acta
2013 | Journal article
Source: Self-asserted source
Paul Swartz

Allosteric modulation of caspase 3 through mutagenesis

Bioscience reports
2012 | Journal article
Source: Self-asserted source
Paul Swartz

Thermodynamic, enzymatic and structural effects of removing a salt bridge at the base of loop 4 in (pro)caspase-3

Archives of biochemistry and biophysics
2011 | Journal article
Source: Self-asserted source
Paul Swartz

Crystallization and preliminary X-ray diffraction analysis of red clover necrotic mosaic virus

Acta crystallographica. Section F, Structural biology and crystallization communications
2010 | Journal article
Source: Self-asserted source
Paul Swartz

A constitutively active and uninhibitable caspase-3 zymogen efficiently induces apoptosis

The Biochemical journal
2009 | Journal article
Source: Self-asserted source
Paul Swartz

Multiple solvent crystal structures of ribonuclease A: an assessment of the method

Proteins
2009 | Journal article
Source: Self-asserted source
Paul Swartz

Role of loop bundle hydrogen bonds in the maturation and activity of (Pro)caspase-3

Biochemistry
2006 | Journal article
Source: Self-asserted source
Paul Swartz

Comparative mutagenicity of halomethanes and halonitromethanes in Salmonella TA100: structure-activity analysis and mutation spectra

Mutation research
2004 | Journal article
Source: Self-asserted source
Paul Swartz

Mutagenicity in Salmonella of halonitromethanes: a recently recognized class of disinfection by-products in drinking water

Mutation research
2004 | Journal article
Source: Self-asserted source
Paul Swartz

Pulsed-alkylation mass spectrometry for the study of protein folding and dynamics: development and application to the study of a folding/unfolding intermediate of bacterial luciferase

Biochemistry
2001 | Journal article
Source: Self-asserted source
Paul Swartz

Use of structure-activity relationships for probing biochemical mechanisms: glutathione transferase zeta conjugation of haloacids

Advances in experimental medicine and biology
2001 | Journal article
Source: Self-asserted source
Paul Swartz

Protein contributions to redox potentials of homologous rubredoxins: an energy minimization study

Biophysical journal
1997 | Journal article
Source: Self-asserted source
Paul Swartz

Computational models of redox proteins and protein model building

Computational models of redox proteins and protein model building
1996 | Dissertation or Thesis
Source: Self-asserted source
Paul Swartz

Structural origins of redox potentials in Fe-S proteins: electrostatic potentials of crystal structures

Biophysical journal
1996 | Journal article
Source: Self-asserted source
Paul Swartz

Temperature dependence of the redox potential of rubredoxin from Pyrococcus furiosus: a molecular dynamics study

Biochemistry
1996 | Journal article
Source: Self-asserted source
Paul Swartz

Molecular dynamics simulation studies of electron transfer properties of iron-sulfur proteins.

34th Hanford Symposium on Health and the Environment
1995 | Book chapter
Source: Self-asserted source
Paul Swartz