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Scopus Author ID: 35993985700

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Employment (3)

University of Maryland School of Medicine: Baltimore, MD, US

2004-07-01 to present (Biochemistry and Molecular Biology)
Employment
Source: Self-asserted source
Sergiy Yakovlev

The American Red Cross Holland Laboratory: Rockville, MD, US

1997-12-07 to 2004-06-30 (Biochemistry)
Employment
Source: Self-asserted source
Sergiy Yakovlev

Palladin Institute of Biochemistry: Kiev, UA

1991-08-01 to 1997-12-01
Employment
Source: Self-asserted source
Sergiy Yakovlev

Works (37)

Identification of Neural (N)-Cadherin as a Novel Endothelial Cell Receptor for Fibrin and Localization of the Complementary Binding Sites

Biochemistry
2024 | Journal article
DOI: 10.1021/acs.biochem.3c00475
EID:

2-s2.0-85181562576

Part of ISSN: 15204995 00062960
Contributors: Yakovlev, S.; Tjandra, N.; Strickland, D.D.; Medved, L.
Source: Self-asserted source
Sergiy Yakovlev via Scopus - Elsevier

Current View on the Molecular Mechanisms Underlying Fibrin(ogen)-Dependent Inflammation

Thrombosis and Haemostasis
2022 | Journal article
DOI: 10.1055/a-1910-4538
EID:

2-s2.0-85135738771

Part of ISSN: 03406245
Contributors: Yakovlev, S.; Strickland, D.K.; Medved, L.
Source: Self-asserted source
Sergiy Yakovlev via Scopus - Elsevier

Dual functions of the fibrin βN-domains in the VLDL receptor-dependent pathway of transendothelial migration of leukocytes

Thrombosis Research
2022 | Journal article
DOI: 10.1016/j.thromres.2022.04.002
EID:

2-s2.0-85128204102

Part of ISSN: 18792472 00493848
Contributors: Yakovlev, S.; Medved, L.
Source: Self-asserted source
Sergiy Yakovlev via Scopus - Elsevier

Structural Basis for the Interaction of Fibrin with the Very Low-Density Lipoprotein Receptor Revealed by NMR and Site-Directed Mutagenesis

Biochemistry
2021 | Journal article
DOI: 10.1021/acs.biochem.1c00378
EID:

2-s2.0-85113685400

Part of ISSN: 15204995 00062960
Contributors: Gruschus, J.M.; Yakovlev, S.; Banerjee, K.; Medved, L.; Tjandra, N.
Source: Self-asserted source
Sergiy Yakovlev via Scopus - Elsevier

Structure and function of fibrinogen bβn-domains

Ukrainian Biochemical Journal
2020 | Journal article
DOI: 10.15407/ubj92.03.022
EID:

2-s2.0-85090535172

Part of ISSN: 24135003 24094943
Contributors: Medved, L.; Yakovlev, S.
Source: Self-asserted source
Sergiy Yakovlev via Scopus - Elsevier

Fibrin-VLDL Receptor-Dependent Pathway Promotes Leukocyte Transmigration by Inhibiting Src Kinase Fyn and is a Target for Fibrin β15-42 Peptide

Thrombosis and Haemostasis
2019 | Journal article
DOI: 10.1055/s-0039-1695008
EID:

2-s2.0-85074305875

Part of ISSN: 03406245
Contributors: Yakovlev, S.; Cao, C.; Galisteo, R.; Zhang, L.; Strickland, D.K.; Medved, L.
Source: Self-asserted source
Sergiy Yakovlev via Scopus - Elsevier

Effect of fibrinogen, fibrin, and fibrin degradation products on transendothelial migration of leukocytes

Thrombosis Research
2018 | Journal article
DOI: 10.1016/j.thromres.2017.11.007
EID:

2-s2.0-85035044664
Contributors: Yakovlev, S.; Medved, L.
Source: Self-asserted source
Sergiy Yakovlev via Scopus - Elsevier

Nuclear Magnetic Resonance Solution Structure of the Recombinant Fragment Containing Three Fibrin-Binding Cysteine-Rich Domains of the Very Low Density Lipoprotein Receptor

Biochemistry
2018 | Journal article
DOI: 10.1021/acs.biochem.8b00349
EID:

2-s2.0-85049654055

Part of ISSN: 15204995 00062960
Contributors: Banerjee, K.; Yakovlev, S.; Gruschus, J.M.; Medved, L.; Tjandra, N.
Source: Self-asserted source
Sergiy Yakovlev via Scopus - Elsevier

Interaction of Fibrin with the Very Low-Density Lipoprotein (VLDL) Receptor: Further Characterization and Localization of the VLDL Receptor-Binding Site in Fibrin βn-Domains

Biochemistry
2017 | Journal article
DOI: 10.1021/acs.biochem.7b00087
EID:

2-s2.0-85019462588
Contributors: Yakovlev, S.; Medved, L.
Source: Self-asserted source
Sergiy Yakovlev via Scopus - Elsevier

Anti-VLDL receptor monoclonal antibodies inhibit fibrin-VLDL receptor interaction and reduce fibrin-dependent leukocyte transmigration

Thrombosis and Haemostasis
2016 | Journal article
DOI: 10.1160/TH16-04-0333
EID:

2-s2.0-85004008269
Contributors: Yakovlev, S.; Belkin, A.M.; Chen, L.; Cao, C.; Zhang, L.; Strickland, D.K.; Medved, L.
Source: Self-asserted source
Sergiy Yakovlev via Scopus - Elsevier

Interaction of Fibrin with the Very Low Density Lipoprotein Receptor: Further Characterization and Localization of the Fibrin-Binding Site

Biochemistry
2015 | Journal article
DOI: 10.1021/acs.biochem.5b00582
EID:

2-s2.0-84938674941
Contributors: Yakovlev, S.; Medved, L.
Source: Self-asserted source
Sergiy Yakovlev via Scopus - Elsevier

Aciculin interacts with filamin C and Xin and is essential for myofibril assembly, remodeling and maintenance

Journal of Cell Science
2014 | Journal article
DOI: 10.1242/jcs.152157
EID:

2-s2.0-84906070265
Contributors: Molt, S.; Bührdel, J.B.; Yakovlev, S.; Schein, P.; Orfanos, Z.; Kirfel, G.; Winter, L.; Wiche, G.; Van Der Ven, P.F.; Rottbauer, W. et al.
Source: Self-asserted source
Sergiy Yakovlev via Scopus - Elsevier

Polymerisation of fibrin αC-domains promotes endothelial cell migration and proliferation

Thrombosis and Haemostasis
2014 | Journal article
DOI: 10.1160/TH14-01-0079
EID:

2-s2.0-84914127316
Contributors: Sergiy, Y.; Mikhailenko, I.; Galina, T.; Belkin, A.M.; Medved, L.
Source: Self-asserted source
Sergiy Yakovlev via Scopus - Elsevier

The interaction of integrin α<inf>iIb</inf> β<inf>3</inf> with fibrin occurs through multiple binding sites in the α <inf>IIb</inf> β-propeller domain

Journal of Biological Chemistry
2014 | Journal article
DOI: 10.1074/jbc.M113.518126
EID:

2-s2.0-84893118880
Contributors: Podolnikova, N.P.; Yakovlev, S.; Yakubenko, V.P.; Wang, X.; Gorkun, O.V.; Ugarova, T.P.
Source: Self-asserted source
Sergiy Yakovlev via Scopus - Elsevier

Identification of VLDLR as a novel endothelial cell receptor for fibrin that modulates fibrin-dependent transendothelial migration of leukocytes

Blood
2012 | Journal article
DOI: 10.1182/blood-2011-09-382580
EID:

2-s2.0-84862955818
Contributors: Yakovlev, S.; Mikhailenko, I.; Cao, C.; Zhang, L.; Strickland, D.K.; Medved, L.
Source: Self-asserted source
Sergiy Yakovlev via Scopus - Elsevier

Interaction of fibrin with VE-cadherin and anti-inflammatory effect of fibrin-derived fragments

Journal of Thrombosis and Haemostasis
2011 | Journal article
DOI: 10.1111/j.1538-7836.2011.04438.x
EID:

2-s2.0-80052418733
Contributors: Yakovlev, S.; Gao, Y.; Cao, C.; Chen, L.; Strickland, D.K.; Zhang, L.; Medved, L.
Source: Self-asserted source
Sergiy Yakovlev via Scopus - Elsevier

Noncovalent interaction of α<inf>2</inf>-antiplasmin with fibrin(ogen): Localization of α<inf>2</inf>-antiplasmin-binding sites

Biochemistry
2010 | Journal article
DOI: 10.1021/bi1010317
EID:

2-s2.0-77956161958
Contributors: Tsurupa, G.; Yakovlev, S.; McKee, P.; Medved, L.
Source: Self-asserted source
Sergiy Yakovlev via Scopus - Elsevier

Biomolecular characterization of CD44-fibrin(ogen) binding distinct molecular requirements mediate binding of standard and variant isoforms of CD44 to immobilized fibrin(ogen)

Journal of Biological Chemistry
2009 | Journal article
DOI: 10.1074/jbc.M805144200
EID:

2-s2.0-59449098391
Contributors: Alves, C.S.; Yakovlev, S.; Medved, L.; Konstantopoulos, K.
Source: Self-asserted source
Sergiy Yakovlev via Scopus - Elsevier

Interaction of fibrin(ogen) with the endothelial cell receptor VE-cadherin: Localization of the fibrin-binding site within the third extracellular VE-cadherin domain

Biochemistry
2009 | Journal article
DOI: 10.1021/bi900487d
EID:

2-s2.0-67049158447
Contributors: Yakovlev, S.; Medved, L.
Source: Self-asserted source
Sergiy Yakovlev via Scopus - Elsevier

Direct evidence for specific interactions of the fibrinogen αC-domains with the central E region and with each other

Biochemistry
2007 | Journal article
DOI: 10.1021/bi700944j
EID:

2-s2.0-34547753415
Contributors: Litvinov, R.I.; Yakovlev, S.; Tsurupa, G.; Gorkun, O.V.; Medved, L.; Weisel, J.W.
Source: Self-asserted source
Sergiy Yakovlev via Scopus - Elsevier

Plasma fibrinogen γ′ chain content in the thrombotic microangiopathy syndrome

Journal of Thrombosis and Haemostasis
2007 | Journal article
DOI: 10.1111/j.1538-7836.2006.02270.x
EID:

2-s2.0-33845524471
Contributors: Mosesson, M.W.; Hernandez, I.; Raife, T.J.; Medved, L.; Yakovlev, S.; Simpson-Haidaris, P.J.; Uitte De Willige, S.; Bertina, R.M.
Source: Self-asserted source
Sergiy Yakovlev via Scopus - Elsevier

Polymerization of fibrin: Direct observation and quantification of individual B:b knob-hole interactions

Blood
2007 | Journal article
DOI: 10.1182/blood-2006-07-033910
EID:

2-s2.0-33846017609
Contributors: Litvinov, R.I.; Gorkun, O.V.; Galanakis, D.K.; Yakovlev, S.; Medved, L.; Shuman, H.; Weisel, J.W.
Source: Self-asserted source
Sergiy Yakovlev via Scopus - Elsevier

Integrin αIIbβ3:ligand interactions are linked to binding-site remodeling

Protein Science
2006 | Journal article
DOI: 10.1110/ps.052049506
EID:

2-s2.0-33746571991
Contributors: Hantgan, R.R.; Stahle, M.C.; Connor, J.H.; Horita, D.A.; Rocco, M.; Mclane, M.; Yakovlev, S.; Medved, L.
Source: Self-asserted source
Sergiy Yakovlev via Scopus - Elsevier

Interaction of fibrin(ogen) with apolipoprotein(a): Further characterization and identification of a novel lysine-dependent apolipoprotein(a)-binding site within the γ chain 287-411 region

Biochemistry
2006 | Journal article
DOI: 10.1021/bi060526h
EID:

2-s2.0-33748279691
Contributors: Tsurupa, G.; Yakovlev, S.; Pechik, I.; Lamanuzzi, L.B.; Anglés-Cano, E.; Medved, L.
Source: Self-asserted source
Sergiy Yakovlev via Scopus - Elsevier

Structural basis for sequential cleavage of fibrinopeptides upon fibrin assembly

Biochemistry
2006 | Journal article
DOI: 10.1021/bi0525369
EID:

2-s2.0-33645211889
Contributors: Pechik, I.; Yakovlev, S.; Mosesson, M.W.; Gilliland, G.L.; Medved, L.
Source: Self-asserted source
Sergiy Yakovlev via Scopus - Elsevier

Interaction of fibrin(ogen) with leukocyte receptor α <inf>M</inf>β<inf>2</inf> (Mac-1): Further characterization and identification of a novel binding region within the central domain of the fibrinogen γ-module

Biochemistry
2005 | Journal article
DOI: 10.1021/bi048266w
EID:

2-s2.0-12144285007
Contributors: Yakovlev, S.; Zhang, L.; Ugarova, T.; Medved, L.
Source: Self-asserted source
Sergiy Yakovlev via Scopus - Elsevier

Multiple binding sites in fibrinogen for integrin α<inf>M</inf>β <inf>2</inf> (Mac-1)

Journal of Biological Chemistry
2004 | Journal article
DOI: 10.1074/jbc.M408012200
EID:

2-s2.0-7244260462
Contributors: Lishko, V.K.; Podolnikova, N.P.; Yakubenko, V.P.; Yakovlev, S.; Medved, L.; Yadav, S.P.; Ugarova, T.P.
Source: Self-asserted source
Sergiy Yakovlev via Scopus - Elsevier

Interaction of fibrin(ogen) with heparin: Further characterization and localization of the heparin-binding site

Biochemistry
2003 | Journal article
DOI: 10.1021/bi0344073
EID:

2-s2.0-0037663710
Contributors: Yakovlev, S.; Gorlatov, S.; Ingham, K.; Medved, L.
Source: Self-asserted source
Sergiy Yakovlev via Scopus - Elsevier

Conformational changes upon conversion of fibrinogen into fibrin: The mechanisms of exposure of cryptic sites

Annals of the New York Academy of Sciences
2001 | Conference paper
DOI: 10.1111/j.1749-6632.2001.tb03505.x
EID:

2-s2.0-0034969112

Part of ISSN: 00778923
Contributors: Medved, L.; Tsurupa, G.; Yakovlev, S.
Source: Self-asserted source
Sergiy Yakovlev via Scopus - Elsevier

Crystal structure of the central region of bovine fibrinogen (E<inf>5</inf> fragment) at 1.4-Å resolution

Proceedings of the National Academy of Sciences of the United States of America
2001 | Journal article
DOI: 10.1073/pnas.211439798
EID:

2-s2.0-0035834058
Contributors: Madrazo, J.; Brown, J.H.; Litvinovich, S.; Dominguez, R.; Yakovlev, S.; Medved, L.; Cohen, C.
Source: Self-asserted source
Sergiy Yakovlev via Scopus - Elsevier

Some indices of haemostasis during Lewis lung carcinoma growth

Experimental Oncology
2001 | Journal article
EID:

2-s2.0-0012792645

Part of ISSN: 02043564
Contributors: Petik, A.V.; Platonova, T.N.; Andrianov, S.I.; Pyaskovskaya, O.N.; Savchuk, A.N.; Lukinova, N.I.; Yakovlev, S.A.; Chekhun, V.F.
Source: Self-asserted source
Sergiy Yakovlev via Scopus - Elsevier

Structural and functional role of the β-strand insert (γ381-390) in the fibrinogen γ-module: A "pull out" hypothesis

Annals of the New York Academy of Sciences
2001 | Conference paper
DOI: 10.1111/j.1749-6632.2001.tb03499.x
EID:

2-s2.0-0034973467

Part of ISSN: 00778923
Contributors: Yakovlev, S.; Loukinov, D.; Medved, L.
Source: Self-asserted source
Sergiy Yakovlev via Scopus - Elsevier

Activation of plasminogen by antiplasminogen monoclonal antibody IV-1c: Properties and mechanism of reaction

Ukrain'skyi Biokhimichnyi Zhurnal
2000 | Journal article
EID:

2-s2.0-29244464345

Part of ISSN: 02018470
Contributors: Makogonenko, E.M.; Yakovlev, S.A.; Slominsky, S.Yu.; Korolchuk, V.I.; Grinenko, T.V.; Sokolovskaya, L.I.; Druzhina, N.N.; Kolesnikova, I.N.; Chernyshov, V.I.; Cederholm-Williams, S.A.
Source: Self-asserted source
Sergiy Yakovlev via Scopus - Elsevier

Conversion of fibrinogen to fibrin: Mechanism of exposure of tPA- and plasminogen-binding sites

Biochemistry
2000 | Journal article
DOI: 10.1021/bi001847a
EID:

2-s2.0-0034719105
Contributors: Yakovlev, S.; Makogonenko, E.; Kurochkina, N.; Nieuwenhuizen, W.; Ingham, K.; Medved, L.
Source: Self-asserted source
Sergiy Yakovlev via Scopus - Elsevier

Role of the β-strand insert in the central domain of the fibrinogen γ-module

Biochemistry
2000 | Journal article
DOI: 10.1021/bi001836h
EID:

2-s2.0-0034719137
Contributors: Yakovlev, S.; Litvinovich, S.; Loukinov, D.; Medved, L.
Source: Self-asserted source
Sergiy Yakovlev via Scopus - Elsevier

Studies of the t-PA-catalyzed Glu-plasminogen activation on different models of polymeric fibrin

Thrombosis Research
1997 | Journal article
DOI: 10.1016/S0049-3848(97)00112-6
EID:

2-s2.0-0030749313

Part of ISSN: 00493848
Contributors: Druzhyna, N.N.; Makogonenko, E.M.; Yakovlev, S.A.
Source: Self-asserted source
Sergiy Yakovlev via Scopus - Elsevier

Activating effect of the plasminogen activators on plasminogens of different mammalia species

Thrombosis Research
1995 | Journal article
DOI: 10.1016/0049-3848(95)00131-A
EID:

2-s2.0-0029116014

Part of ISSN: 00493848
Contributors: Yakovlev, S.A.; Rublenko, M.V.; Izdepsky, V.I.; Makogonenko, E.M.
Source: Self-asserted source
Sergiy Yakovlev via Scopus - Elsevier
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