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Education and qualifications (1)

Medical University of Innsbruck: Innsbruck, Tyrol, AT

Univ.-Prof., Dr. (Pharmacology and Genetics)
Education
Source: Self-asserted source
Gottfried Baier

Funding (13)

Host Protective Engineering of Cancer Immunity, Acronym: HOPE

2018 to 2023 | Grant
ERC: European Research Council (Brüssel, BE)
Part of GRANT_NUMBER:

786462 - HOPE (Coord. Gottfried Baier)

Source: Self-asserted source
Gottfried Baier

Austrian Science Funds: Nuclear receptors as cancer immune checkpoint

2018 to 2022 | Grant
FWF (Wien, AT)
GRANT_NUMBER:

P31383 (Gottfried Baier)

Source: Self-asserted source
Gottfried Baier

Austrians Science Funds: Adenosine A2A receptor function(s) in the patho-physiology of immune diseases

2017 to 2021 | Grant
FWF (Wien, AT)
GRANT_NUMBER:

P30324 (Gottfried Baier)

Source: Self-asserted source
Gottfried Baier

CD Laboratory for Immune Therapy-mediated Cancer Rejection via NR2F6 blockade

2016 to 2020 | Grant
Christian Doppler Forschungsgesellschaft (Wien, AT)
Part of GRANT_NUMBER:

Acronym: I-Care (Coord. Gottfried Baier)

Source: Self-asserted source
Gottfried Baier

Austrian Sience Funds: NR2F6 governs immune defense against microbial pathogens

2016 to 2019 | Grant
FWF (Austria, AT)
Part of GRANT_NUMBER:

P28694 (Natascha Kleiter)

Source: Self-asserted source
Gottfried Baier

Austrian Science Funds: Analysis of the TGFß/Cbl-b pathway in autoimmunity and tumor immunity

2014 to 2018 | Grant
FWF (Austria, AT)
Part of GRANT_NUMBER:

P25828 (Thomas Gruber)

Source: Self-asserted source
Gottfried Baier

Austrian Science Funds: PKCtheta/Coro1A axis in CD4+ T cell subpopulations

2014 to 2018 | Grant
FWF (Austria, AT)
GRANT_NUMBER:

Lise Meitner Program M1636 (Kerstin Siegmund & Gottfried Baier)

Source: Self-asserted source
Gottfried Baier

Austrian Research Promotion Agency: Acronym CBL-AIM: Blocking Cbl-b immune-inhibitory signaling pathways as a unique cancer therapeutic target

2014 to 2017 | Grant
FFG Bridge (Austria, AT)
GRANT_NUMBER:

842388 (Gottfried Baier)

Source: Self-asserted source
Gottfried Baier

Analysis of PKCalpha-mediated regulation of TGFbeta receptor signaling in T cells

Source: Self-asserted source
Gottfried Baier via DimensionsWizard

Mechanistic role of PKCtheta autophosphorylation at Thr219

2007-03-01 to 2010-12-31 | Grant
Austrian Science Fund (Vienna, AT)
GRANT_NUMBER:

P 19505-B05

Source: Self-asserted source
Gottfried Baier via DimensionsWizard

Physiological roles of PKC alpha and theta in T lymphocytes

2003-02-01 to 2006-01-31 | Grant
Austrian Science Fund (Vienna, AT)
GRANT_NUMBER:

P 16229-B13

Source: Self-asserted source
Gottfried Baier via DimensionsWizard

Analysis of protein kinase C - theta function

2000-05-01 to 2002-07-31 | Grant
Austrian Science Fund (Vienna, AT)
GRANT_NUMBER:

P 14394-B07

Source: Self-asserted source
Gottfried Baier via DimensionsWizard

Protein Kinase C-Theta (PKC-Theta#), a key regulator in T cell activation !?

1997-02-01 to 2000-07-31 | Grant
Austrian Science Fund (Vienna, AT)
GRANT_NUMBER:

P 12104-B01

Source: Self-asserted source
Gottfried Baier via DimensionsWizard

Works (50 of 131)

Items per page:
Page 1 of 3

Regulation of NK cell development, maturation, and antitumor responses by the nuclear receptor NR2F6

Cell Death & Disease
2025-02-07 | Journal article
Contributors: Johannes Woelk; Florian Hornsteiner; Stephanie Aschauer-Wallner; Patrizia Stoitzner; Gottfried Baier; Natascha Hermann-Kleiter
Source: check_circle
Crossref

T cell‐intrinsic PKD3 fine‐tunes differentiation into CD8+ central memory T cells and CD8 single positive thymocyte development

Immunology
2024-09 | Journal article
Contributors: Jiří Koutník; Sebastian Peer; Dominik Humer; Grzegorz Sumara; Michael Leitges; Gottfried Baier; Kerstin Siegmund
Source: check_circle
Crossref

PKN1 Exerts Neurodegenerative Effects in an In Vitro Model of Cerebellar Hypoxic–Ischemic Encephalopathy via Inhibition of AKT/GSK3β Signaling

Biomolecules
2023-10-31 | Journal article
Contributors: Stephanie zur Nedden; Motahareh Solina Safari; Friedrich Fresser; Klaus Faserl; Herbert Lindner; Bettina Sarg; Gottfried Baier; Gabriele Baier-Bitterlich
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

A MLR-Based Approach to Analyze Regulators of T Lymphocyte Activation In Vivo

International Journal of Molecular Sciences
2022-05-10 | Journal article
Contributors: Jiří Koutník; Victoria Klepsch; Maria Pommermayr; Nikolaus Thuille; Gottfried Baier; Kerstin Siegmund
Source: check_circle
Crossref

Emerging Next-Generation Target for Cancer Immunotherapy Research: The Orphan Nuclear Receptor NR2F6

Cancers
2021-05-26 | Journal article
Contributors: Victoria Klepsch; Kerstin Siegmund; Gottfried Baier
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Loss of the orphan nuclear receptor NR2F6 enhances CD8+ T-cell memory via IFN-γ

Cell Death & Disease
2021-02-15 | Journal article
Contributors: Bojana Jakic; William J. Olson; Kerstin Siegmund; Victoria Klepsch; Janine Kimpel; Verena Labi; Dietmar Zehn; Gottfried Baier; Natascha Hermann-Kleiter
Source: check_circle
Crossref

Development of a fast and sensitive method to study transcription factor activation under endogenous conditions in primary mouse T cells applying Alpha technology

Journal of Immunological Methods
2019-08 | Journal article
Contributors: Niκolaus Thuille; Gottfried Baier
Source: check_circle
Crossref

Targeting immune checkpoints potentiates immunoediting and changes the dynamics of tumor evolution

Nature Communications
2018-12 | Journal article
Part of ISSN: 2041-1723
Source: Self-asserted source
Gottfried Baier
grade
Preferred source (of 2)‎

NAD metabolism fuels human and mouse intestinal inflammation

Gut
2018-10 | Journal article
Part of ISSN: 0017-5749
Part of ISSN: 1468-3288
Source: Self-asserted source
Gottfried Baier

Regulation of Lymphatic GM-CSF Expression by the E3 Ubiquitin Ligase Cbl-b

Frontiers in Immunology
2018-10-08 | Journal article
Part of ISSN: 1664-3224
Source: Self-asserted source
Gottfried Baier

Nuclear orphan receptor NR2F6 as a safeguard against experimental murine colitis

Gut
2018-08 | Journal article
Part of ISSN: 0017-5749
Part of ISSN: 1468-3288
Source: Self-asserted source
Gottfried Baier

Nuclear receptor NR2F6 inhibition potentiates responses to PD-L1/PD-1 cancer immune checkpoint blockade.

Nature communications
2018-04-18 | Journal article
Source: Self-asserted source
Gottfried Baier

Protein kinase N1 critically regulates cerebellar development and long-term function

Journal of Clinical Investigation
2018-04-16 | Journal article
Part of ISSN: 0021-9738
Part of ISSN: 1558-8238
Source: Self-asserted source
Gottfried Baier

Cblb-deficient T cells are less susceptible to PD-L1-mediated inhibition.

Oncotarget
2017-06-01 | Journal article
Source: Self-asserted source
Gottfried Baier

Protein kinase C theta is dispensable for suppression mediated by CD25+CD4+ regulatory T cells

PLOS ONE
2017-05-22 | Journal article
Part of ISSN: 1932-6203
Source: Self-asserted source
Gottfried Baier

Beyond CTLA-4 and PD-1: Orphan nuclear receptor NR2F6 as T cell signaling switch and emerging target in cancer immunotherapy.

Immunology letters
2016-10-15 | Journal article
Source: Self-asserted source
Gottfried Baier

Novel Insights into the PKCβ-dependent Regulation of the Oxidoreductase p66Shc.

The Journal of biological chemistry
2016-09-13 | Journal article
Source: Self-asserted source
Gottfried Baier

Proof of Principle for a T Lymphocyte Intrinsic Function of Coronin 1A.

The Journal of biological chemistry
2016-08-26 | Journal article
Source: Self-asserted source
Gottfried Baier

Role of PKCtheta in macrophage-mediated immune response to Salmonella typhimurium infection in mice.

Cell communication and signaling : CCS
2016-07-28 | Journal article
Source: Self-asserted source
Gottfried Baier

Inhibition of CBLB protects from lethal Candida albicans sepsis.

Nature medicine
2016-07-18 | Journal article
Source: Self-asserted source
Gottfried Baier

cJun N-terminal kinase (JNK) phosphorylation of serine 36 is critical for p66Shc activation.

Scientific reports
2016-02-12 | Journal article
Source: Self-asserted source
Gottfried Baier

The Nuclear Orphan Receptor NR2F6 Is a Central Checkpoint for Cancer Immune Surveillance.

Cell reports
2015-09-17 | Journal article
Source: Self-asserted source
Gottfried Baier

Novel protein kinase C θ: coronin 1A complex in T lymphocytes.

Cell communication and signaling : CCS
2015-03-31 | Journal article
Source: Self-asserted source
Gottfried Baier

Protein kinase Cθ: the pleiotropic T-cell signalling intermediate.

Biochemical Society transactions
2014-12-01 | Book chapter
Source: Self-asserted source
Gottfried Baier

Orphan nuclear receptor NR2F6 acts as an essential gatekeeper of Th17 CD4+ T cell effector functions.

Cell communication and signaling : CCS
2014-06-12 | Book chapter
Source: Self-asserted source
Gottfried Baier

Protein kinase C θ regulates the phenotype of murine CD4+ Th17 cells.

PloS one
2014-05-02 | Journal article
Source: Self-asserted source
Gottfried Baier

LAMTOR2-mediated modulation of NGF/MAPK activation kinetics during differentiation of PC12 cells.

PloS one
2014-04-21 | Journal article
Source: Self-asserted source
Gottfried Baier

The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells.

Nature
2014-02-19 | Journal article
Source: Self-asserted source
Gottfried Baier

The role of the e3 ligase cbl-B in murine dendritic cells.

PloS one
2013-06-06 | Journal article
Source: Self-asserted source
Gottfried Baier

Cbl-b mediates TGFβ sensitivity by downregulating inhibitory SMAD7 in primary T cells.

Journal of molecular cell biology
2013-05-24 | Journal article
Source: Self-asserted source
Gottfried Baier

PKC-θ exists in an oxidized inactive form in naive human T cells.

European journal of immunology
2013-04-12 | Journal article
Source: Self-asserted source
Gottfried Baier

PKCα and PKCβ cooperate functionally in CD3-induced de novo IL-2 mRNA transcription.

Immunology letters
2013-02-21 | Journal article
Source: Self-asserted source
Gottfried Baier

PKCθ/β and CYLD are antagonistic partners in the NFκB and NFAT transactivation pathways in primary mouse CD3+ T lymphocytes.

PloS one
2013-01-15 | Journal article
Source: Self-asserted source
Gottfried Baier

The kinase PKCα selectively upregulates interleukin-17A during Th17 cell immune responses.

Immunity
2013-01-03 | Journal article
Source: Self-asserted source
Gottfried Baier

Loss of PIDD limits NF-κB activation and cytokine production but not cell survival or transformation after DNA damage.

Cell death and differentiation
2012-12-14 | Journal article
Source: Self-asserted source
Gottfried Baier

Adoptive transfer of siRNA Cblb-silenced CD8+ T lymphocytes augments tumor vaccine efficacy in a B16 melanoma model.

PloS one
2012-09-04 | Journal article
Source: Self-asserted source
Gottfried Baier

Nuclear orphan receptor NR2F6 directly antagonizes NFAT and RORγt binding to the Il17a promoter.

Journal of autoimmunity
2012-08-24 | Journal article
Source: Self-asserted source
Gottfried Baier

Syk kinase-coupled C-type lectin receptors engage protein kinase C-σ to elicit Card9 adaptor-mediated innate immunity.

Immunity
2012-01-27 | Journal article
Source: Self-asserted source
Gottfried Baier

Coronin 1A is an essential regulator of the TGFβ receptor/SMAD3 signaling pathway in Th17 CD4(+) T cells.

Journal of autoimmunity
2011-06-22 | Journal article
Source: Self-asserted source
Gottfried Baier

Reinforcement of cancer immunotherapy by adoptive transfer of cblb-deficient CD8+ T cells combined with a DC vaccine.

Immunology and cell biology
2011-03-08 | Journal article
Source: Self-asserted source
Gottfried Baier

Essential role of E3 ubiquitin ligase activity in Cbl-b-regulated T cell functions.

Journal of immunology (Baltimore, Md. : 1950)
2011-01-19 | Journal article
Source: Self-asserted source
Gottfried Baier

PKCtheta is necessary for efficient activation of NFkappaB, NFAT, and AP-1 during positive selection of thymocytes.

Immunology letters
2010-08-16 | Journal article
Source: Self-asserted source
Gottfried Baier

NFAT pulls the strings during CD4+ T helper cell effector functions.

Blood
2010-01-26 | Book chapter
Source: Self-asserted source
Gottfried Baier

PKCtheta and Itk functionally interact during primary mouse CD3+ T cell activation.

Immunology letters
2009-08-12 | Journal article
Source: Self-asserted source
Gottfried Baier

PKC-theta modulates the strength of T cell responses by targeting Cbl-b for ubiquitination and degradation.

Science signaling
2009-06-23 | Journal article
Source: Self-asserted source
Gottfried Baier

The potent protein kinase C-selective inhibitor AEB071 (sotrastaurin) represents a new class of immunosuppressive agents affecting early T-cell activation.

The Journal of pharmacology and experimental therapeutics
2009-06-02 | Journal article
Source: Self-asserted source
Gottfried Baier

PKC theta cooperates with PKC alpha in alloimmune responses of T cells in vivo.

Molecular immunology
2009-04-07 | Journal article
Source: Self-asserted source
Gottfried Baier

PKC inhibitors: potential in T cell-dependent immune diseases.

Current opinion in cell biology
2009-04-03 | Book chapter
Source: Self-asserted source
Gottfried Baier

PKC-theta selectively controls the adhesion-stimulating molecule Rap1.

Blood
2008-09-16 | Journal article
Source: Self-asserted source
Gottfried Baier

The nuclear orphan receptor NR2F6 suppresses lymphocyte activation and T helper 17-dependent autoimmunity.

Immunity
2008-08-01 | Journal article
Source: Self-asserted source
Gottfried Baier
Items per page:
Page 1 of 3

Peer review (3 reviews for 1 publication/grant)

Review activity for Journal for immunotherapy of cancer. (3)