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ResearcherID: C-8321-2009
Loop profile: 1385015

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Employment (3)

Yale School of Medicine: New Haven, CT, US

2018-08-15 to present | Faculty (Genetics)
Employment
Source: Self-asserted source
Dejian Zhao

Yale Center for Genome Analysis (YCGA): Orange, CT, US

2018-08-15 to present | Bioinformatics Scientist
Employment
Source: Self-asserted source
Dejian Zhao

Albert Einstein College of Medicine: The Bronx, New York, US

2013-10-29 to 2018-08-14 | Postdoctoral Research Fellow (Genetics; Neurology)
Employment
Source: Self-asserted source
Dejian Zhao

Works (33)

ASCL1 Drives Tolerance to Osimertinib in EGFR Mutant Lung Cancer in Permissive Cellular Contexts

Cancer Research
2024-04-15 | Journal article
DOI: 10.1158/0008-5472.CAN-23-0438
Contributors: Bomiao Hu; Marc Wiesehöfer; Fernando J. de Miguel; Zongzhi Liu; Lok-Hei Chan; Jungmin Choi; Mary Ann Melnick; Anna Arnal Estape; Zenta Walther; Dejian Zhao et al.
Source: check_circle
Crossref

Auto-sumoylation of the Ubc9 E2 SUMO-conjugating Enzyme Extends Cellular Lifespan

2024-03-21 | Preprint
DOI: 10.21203/rs.3.rs-4016606/v1
Contributors: Hong-Yeoul Ryu; Dong-Won Jeong; Seung Yeon Kim; Seok-Won Jeoung; Dejian Zhao; James Knight; TuKiet Lam; Jong Hwa Jin; Hyun-Shik Lee; Mark Hochstrasser
Source: check_circle
Crossref

RASGRF1 Fusions Activate Oncogenic RAS Signaling and Confer Sensitivity to MEK Inhibition

Clinical Cancer Research
2022-07-15 | Journal article
DOI: 10.1158/1078-0432.CCR-21-4291
Contributors: Lisa Hunihan; Dejian Zhao; Heather Lazowski; Man Li; Yuping Qian; Laura Abriola; Yulia V. Surovtseva; Viswanathan Muthusamy; Lynn T. Tanoue; Bonnie E. Gould Rothberg et al.
Source: check_circle
Crossref

Functional Analysis of MET Exon 14 Skipping Alteration in Cancer Invasion and Metastatic Dissemination

Cancer Research
2022-04-01 | Journal article
DOI: 10.1158/0008-5472.CAN-21-1327
Contributors: Feng Wang; Yang Liu; Wanglong Qiu; Elaine Shum; Monica Feng; Dejian Zhao; Deyou Zheng; Alain Borczuk; Haiying Cheng; Balazs Halmos
Source: check_circle
Crossref

Dynamic innate immune response determines susceptibility to SARS-CoV-2 infection and early replication kinetics

Journal of Experimental Medicine
2021-08-02 | Journal article
DOI: 10.1084/jem.20210583
Contributors: Nagarjuna R. Cheemarla; Timothy A. Watkins; Valia T. Mihaylova; Bao Wang; Dejian Zhao; Guilin Wang; Marie L. Landry; Ellen F. Foxman
Source: check_circle
Crossref

A Burned-Out CD8+ T-cell Subset Expands in the Tumor Microenvironment and Curbs Cancer Immunotherapy

Cancer Discovery
2021-07-01 | Journal article
DOI: 10.1158/2159-8290.CD-20-0962
Contributors: Miguel F. Sanmamed; Xinxin Nie; Shruti S. Desai; Franz Villaroel-Espindola; Ti Badri; Dejian Zhao; Anthony W. Kim; Lan Ji; Tianxiang Zhang; Edward Quinlan et al.
Source: check_circle
Crossref

Induction of interferon signaling and allograft inflammatory factor 1 in macrophages in a mouse model of breast cancer metastases [version 2; peer review: 2 approved, 1 approved with reservations]

2021-06-23 | Journal article
DOI: 10.12688/wellcomeopenres.16569.2
Part of ISSN: 2398-502X
Contributors: Wei Zheng; Dejian Zhao; Hui Zhang; Prameladevi Chinnasamy; Nicholas Sibinga; Jeffrey W. Pollard
Source: check_circle
Wellcome Open Research
grade
Preferred source (of 2)‎

Induction of interferon signaling and allograft inflammatory factor 1 in macrophages in a mouse model of breast cancer metastases

Wellcome Open Research
2021-03-08 | Journal article
DOI: 10.12688/wellcomeopenres.16569.1
Contributors: Wei Zheng; Dejian Zhao; Hui Zhang; Prameladevi Chinnasamy; Nicholas Sibinga; Jeffrey W. Pollard
Source: check_circle
Crossref

Polycomb complexes redundantly maintain epidermal stem cell identity during development

Genes & Development
2021-03-01 | Journal article
DOI: 10.1101/gad.345363.120
Part of ISSN: 0890-9369
Part of ISSN: 1549-5477
Source: Self-asserted source
Dejian Zhao

Multi-omics analysis to identify susceptibility genes for colorectal cancer

Human Molecular Genetics
2021-01 | Journal article
DOI: 10.1093/hmg/ddab021
Part of ISSN: 0964-6906
Contributors: Yuan Yuan; Jiandong Bao; Zhishan Chen; Anna Díez Villanueva; Wanqing Wen; Fangqin Wang; Dejian Zhao; Xianghui Fu; Qiuyin Cai; Jirong Long et al.
Source: Self-asserted source
Dejian Zhao via Crossref Metadata Search

Histone sumoylation promotes Set3 histone-deacetylase complex-mediated transcriptional regulation.

Nucleic acids research
2020-12-01 | Journal article
DOI: 10.1093/nar/gkaa1093
PMID: 33231641
PMC: PMC7708062
Source: Self-asserted source
Dejian Zhao

Genomic sites hypersensitive to ultraviolet radiation.

Proceedings of the National Academy of Sciences of the United States of America
2019-11-13 | Journal article
DOI: 10.1073/pnas.1907860116
PMID: 31723047
Source: Self-asserted source
Dejian Zhao

Lung Mammary Metastases but Not Primary Tumors Induce Accumulation of Atypical Large Platelets and Their Chemokine Expression.

Cell reports
2019-11-01 | Journal article
DOI: 10.1016/j.celrep.2019.10.016
PMID: 31722193
PMC: PMC6919330
Source: Self-asserted source
Dejian Zhao

The Ulp2 SUMO protease promotes transcription elongation through regulation of histone sumoylation.

The EMBO journal
2019-07-17 | Journal article
DOI: 10.15252/embj.2019102003
PMID: 31313851
Source: Self-asserted source
Dejian Zhao

Polycomb Repressive Complex 1 Controls Maintenance of Fungiform Papillae by Repressing Sonic Hedgehog Expression.

Cell reports
2019-07-01 | Journal article
DOI: 10.1016/j.celrep.2019.06.011
PMID: 31269445
PMC: PMC6921245
Source: Self-asserted source
Dejian Zhao

Dissection of Merkel cell formation in hairy and glabrous skin reveals a common requirement for FGFR2-mediated signaling.

Experimental dermatology
2019-02 | Journal article
DOI: 10.1111/exd.13901
PMID: 30758073
Contributors: Nguyen MB; Valdes VJ; Cohen I; Pothula V; Zhao D; Zheng D; Ezhkova E
Source: Self-asserted source
Dejian Zhao via Europe PubMed Central

PRC1 preserves epidermal tissue integrity independently of PRC2.

Genes & development
2018-12 | Journal article
DOI: 10.1101/gad.319939.118
PMID: 30567998
Contributors: Cohen I; Zhao D; Menon G; Nakayama M; Koseki H; Zheng D; Ezhkova E
Source: Self-asserted source
Dejian Zhao via Europe PubMed Central

SMARTcleaner: identify and clean off-target signals in SMART ChIP-seq analysis.

BMC bioinformatics
2018-12 | Journal article
DOI: 10.1186/s12859-018-2577-4
PMID: 30587107
PMC: PMC6307164
Contributors: Zhao D; Zheng D
Source: Self-asserted source
Dejian Zhao via Europe PubMed Central

PRC1 Fine-tunes Gene Repression and Activation to Safeguard Skin Development and Stem Cell Specification.

Cell stem cell
2018-05 | Journal article
DOI: 10.1016/j.stem.2018.04.005
PMID: 29727681
Contributors: Cohen I; Zhao D; Bar C; Valdes VJ; Dauber-Decker KL; Nguyen MB; Nakayama M; Rendl M; Bickmore WA; Koseki H et al.
Source: Self-asserted source
Dejian Zhao via Europe PubMed Central

Enriched expression of genes associated with autism spectrum disorders in human inhibitory neurons.

Translational psychiatry
2018-01 | Journal article
DOI: 10.1038/s41398-017-0058-6
PMID: 29317598
PMC: PMC5802446
Contributors: Wang P; Zhao D; Lachman HM; Zheng D
Source: Self-asserted source
Dejian Zhao via Europe PubMed Central

Characteristics of allelic gene expression in human brain cells from single-cell RNA-seq data analysis

Bmc Genomics
2017 | Journal article
DOI: 10.1186/s12864-017-4261-x
WOSUID:

WOS:000415107600002
Contributors: Zhao, Dejian; Lin, Mingyan; Pedrosa, Erika; Lachman, Herbert M.; Zheng, Deyou
Source: Self-asserted source
Dejian Zhao via ResearcherID

Transcriptome analysis of microglia in a mouse model of Rett syndrome: differential expression of genes associated with microglia/macrophage activation and cellular stress

Molecular Autism
2017 | Journal article
DOI: 10.1186/s13229-017-0134-z
WOSUID:

WOS:000397755500001
Contributors: Zhao, Dejian; Mokhtari, Ryan; Pedrosa, Erika; Birnbaum, Rayna; Zheng, Deyou; Lachman, Herbert M.
Source: Self-asserted source
Dejian Zhao via ResearcherID

Divergence and Rewiring of Regulatory Networks for Neural Development between Human and Other Species

Neurogenesis
2016 | Journal article
SOURCE-WORK-ID:

1007160611823-495
Contributors: Wang, Ping; Zhao, Dejian; Rockowitz, Shira; Zheng, Deyou
Source: Self-asserted source
Dejian Zhao via ResearcherID

Polycomb-Mediated Repression and Sonic Hedgehog Signaling Interact to Regulate Merkel Cell Specification during Skin Development

PLoS Genet
2016 | Journal article
SOURCE-WORK-ID:

1007160611823-496
Contributors: Perdigoto, Carolina N; Dauber, Katherine L; Bar, Carmit; Tsai, Pai-Chi; Valdes, Victor J; Cohen, Idan; Santoriello, Francis J; Zhao, Dejian; Zheng, Deyou; Hsu, Ya-Chieh et al.
Source: Self-asserted source
Dejian Zhao via ResearcherID

Reduced CYFIP1 in Human Neural Progenitors Results in Dysregulation of Schizophrenia and Epilepsy Gene Networks

PloS one
2016 | Journal article
SOURCE-WORK-ID:

1007160611823-497
Contributors: Nebel, Rebecca A; Zhao, Dejian; Pedrosa, Erika; Kirschen, Jill; Lachman, Herbert M; Zheng, Deyou; Abrahams, Brett S
Source: Self-asserted source
Dejian Zhao via ResearcherID

MicroRNA Profiling of Neurons Generated Using Induced Pluripotent Stem Cells Derived from Patients with Schizophrenia and Schizoaffective Disorder, and 22q11.2 Del.

PLoS ONE
2015 | Journal article
SOURCE-WORK-ID:

1007160611824-498
Contributors: Zhao, Dejian; Lin, Mingyan; Chen, Jian; Pedrosa, Erika; Hrabovsky, Anastasia; Fourcade, H. Matthew; Zheng, Deyou; Lachman, Herbert M.
Source: Self-asserted source
Dejian Zhao via ResearcherID

Heat Shock Alters the Expression of Schizophrenia and Autism Candidate Genes in an Induced Pluripotent Stem Cell Model of the Human Telencephalon

PloS one
2014 | Journal article
SOURCE-WORK-ID:

1007160611824-500
Contributors: Lin, Mingyan; Zhao, Dejian; Hrabovsky, Anastasia; Pedrosa, Erika; Zheng, Deyou; Lachman, Herbert M
Source: Self-asserted source
Dejian Zhao via ResearcherID

The locust genome provides insight into swarm formation and long-distance flight

Nature communications
2014 | Journal article
DOI: 10.1038/ncomms3957
WOSUID:

WOS:000331079300001
Contributors: Wang, Xianhui; Fang, Xiaodong; Yang, Pengcheng; Jiang, Xuanting; Jiang, Feng; Zhao, Dejian; Li, Bolei; Cui, Feng; Wei, Jianing; Ma, Chuan et al.
Source: Self-asserted source
Dejian Zhao via ResearcherID

Efficient utilization of aerobic metabolism helps Tibetan locusts conquer hypoxia

BMC genomics
2013 | Journal article
SOURCE-WORK-ID:

1007160611824-502
Contributors: Zhao, Dejian; Zhang, Zhenyu; Cease, Arianne; Harrison, Jon; Kang, Le
Source: Self-asserted source
Dejian Zhao via ResearcherID

Functional modulation of mitochondrial cytochrome c oxidase underlies adaptation to high-altitude hypoxia in a Tibetan migratory locust

Proceedings of the Royal Society of London B: Biological Sciences
2013 | Journal article
SOURCE-WORK-ID:

1007160611824-503
Contributors: Zhang, Zhen-Yu; Chen, Bing; Zhao, De-Jian; Kang, Le
Source: Self-asserted source
Dejian Zhao via ResearcherID

Genome-wide analysis of transcriptional changes in the thoracic muscle of the migratory locust, Locusta migratoria, exposed to hypobaric hypoxia

Journal of Insect Physiology
2012 | Journal article
DOI: http://dx.doi.org/10.1016/j.jinsphys.2012.08.006
Contributors: Zhao, De Jian; Zhang, Zhen Yu; Harrison, Jon; Kang, Le
Source: Self-asserted source
Dejian Zhao via ResearcherID

Identification of condition-specific reference genes from microarray data for locusts exposed to hypobaric hypoxia

FEBS Open Bio
2012 | Journal article
DOI: 10.1016/j.fob.2012.08.001
Contributors: Zhao, De-Jian; Guo, Kun; Kang, Le
Source: Self-asserted source
Dejian Zhao via ResearcherID

Molecular cloning and temporal--spatial expression of I element in gregarious and solitary locusts

Journal of insect physiology
2010 | Journal article
DOI: 10.1016/j.jinsphys.2010.05.007
WOSUID:

WOS:000280376300014
Contributors: Guo, W; Wang, XH; Zhao, DJ; Yang, PC; Kang, L
Source: Self-asserted source
Dejian Zhao via ResearcherID
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