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mass spectrometry, imaging, signal processing, machine learning, bioinformatics, analytical chemistry
Netherlands, United States, Belgium

Activities

Employment (8)

Delft University of Technology: Delft, NL

2022-03 to present | Associate Professor (Delft Center for Systems and Control)
Employment
Source: Self-asserted source
Raf Van de Plas

Vanderbilt University: Nashville, Tennessee, US

2014-12 to present | Adjunct Assistant Professor (Department of Biochemistry)
Employment
Source: Self-asserted source
Raf Van de Plas

Delft University of Technology: Delft, NL

2014-12 to 2022-02 | Assistant Professor (Delft Center for Systems and Control)
Employment
Source: Self-asserted source
Raf Van de Plas

Vanderbilt University: Nashville, Tennessee, US

2012-03 to 2014-11 | Research Faculty – Research Instructor (Department of Biochemistry)
Employment
Source: Self-asserted source
Raf Van de Plas

Vanderbilt University: Nashville, Tennessee, US

2011-01 to 2012-02 | Research Fellow (Department of Biochemistry)
Employment
Source: Self-asserted source
Raf Van de Plas

KU Leuven: Leuven, BE

2010-05 to 2010-10 | Post-doctoral Researcher (Department of Electrical Engineering (ESAT))
Employment
Source: Self-asserted source
Raf Van de Plas

KU Leuven: Leuven, BE

2005-01 to 2010-05 | Doctoral Researcher in Mass Spectral Imaging (Department of Electrical Engineering (ESAT))
Employment
Source: Self-asserted source
Raf Van de Plas

KU Leuven: Leuven, BE

2003-10 to 2004-12 | Doctoral Researcher in Bioinformatics, Proteomics, and Mass Spectrometry (Department of Electrical Engineering (ESAT))
Employment
Source: Self-asserted source
Raf Van de Plas

Education and qualifications (4)

KU Leuven: Leuven, BE

2005 to 2010 | Doctor of Philosophy (PhD), Engineering Sciences, Bioinformatics (Department of Electrical Engineering (ESAT))
Education
Source: Self-asserted source
Raf Van de Plas

KU Leuven: Leuven, BE

2003 to 2004 | Doctoral Researcher, Bioinformatics (engineering, biotech, biochemistry, proteomics, metabolomics, mass spectrometry) (Department of Electrical Engineering (ESAT))
Education
Source: Self-asserted source
Raf Van de Plas

KU Leuven: Leuven, BE

2002 to 2003 | Master, Artificial Intelligence (data mining, artificial intelligence, and advanced computer science)
Education
Source: Self-asserted source
Raf Van de Plas

Groep T - Internationale Hogeschool Leuven: Leuven, BE

1998 to 2002 | Master, Engineering (Electronics - ICT)
Education
Source: Self-asserted source
Raf Van de Plas

Works (50 of 52)

Items per page:
Page 1 of 2

Comparison of macro x‐ray fluorescence and reflectance imaging spectroscopy for the semi‐quantitative analysis of pigments in easel paintings: A study on lead white and blue verditer

X-Ray Spectrometry
2024-11 | Journal article
Contributors: Luís Manuel de Almeida Nieto; Francesca Gabrieli; Annelies van Loon; Victor Gonzalez; Joris Dik; Raf Van de Plas; Matthias Alfeld
Source: check_circle
Crossref

Blind Polarization Demultiplexing of Shaped QAM Signals Assisted by Temporal Correlations

Journal of Lightwave Technology
2024-01-15 | Journal article
Contributors: Vinod Bajaj; Raf Van de Plas; Sander Wahls
Source: check_circle
Crossref

Microscopy-Directed Imaging Mass Spectrometry for Rapid High Spatial Resolution Molecular Imaging of Glomeruli

Journal of the American Society for Mass Spectrometry
2023-07-05 | Journal article
Contributors: Allison B. Esselman; Nathan Heath Patterson; Lukasz G. Migas; Martin Dufresne; Katerina V. Djambazova; Madeline E. Colley; Raf Van de Plas; Jeffrey M. Spraggins
Source: check_circle
Crossref

Autofluorescence Microscopy QC for Multimodal Molecular Imaging

protocols.io
2023-06-19 | Journal article | Author
Contributors: Katerina V. Djambazova; Nathan Patterson; Lukasz Migas; Angela R.S. Kruse; Raf Van de Plas; Jeffrey Spraggins
Source: check_circle
protocols.io

Kidney Functional Tissue Unit (FTU) Segmentation

protocols.io
2023-06-19 | Journal article | Author
Contributors: Katerina V. Djambazova; Nathan Patterson; Raf Van de Plas; Jeffrey Spraggins
Source: check_circle
protocols.io

Rapid Multivariate Analysis Approach to Explore Differential Spatial Protein Profiles in Tissue

Journal of Proteome Research
2023-05-05 | Journal article
Contributors: Kavya Sharman; Nathan Heath Patterson; Andy Weiss; Elizabeth K. Neumann; Emma R. Guiberson; Daniel J. Ryan; Danielle B. Gutierrez; Jeffrey M. Spraggins; Raf Van de Plas; Eric P. Skaar et al.
Source: check_circle
Crossref

MALDI IMS-Derived Molecular Contour Maps: Augmenting Histology Whole-Slide Images

Journal of the American Society for Mass Spectrometry
2023-05-03 | Journal article
Contributors: Kavya Sharman; Nathan Heath Patterson; Lukasz G. Migas; Elizabeth K. Neumann; Jamie Allen; Katherine N. Gibson-Corley; Jeffrey M. Spraggins; Raf Van de Plas; Eric P. Skaar; Richard M. Caprioli
Source: check_circle
Crossref

VU TIS Multimodal Molecular Imaging Pipeline for KPMP Biopsy Interrogation v1

2023-02-13 | Preprint
Contributors: Katerina V Djambazova; Lukasz Migas; Martin Dufresne; Jamie Allen; Madeline E. Colley; Angela R.S. Kruse; Melissa Farrow; Raf Van De Plas; Jeff Spraggins
Source: check_circle
Crossref

MALDI TIMS IMS of Disialoganglioside Isomers─GD1a and GD1b in Murine Brain Tissue

Analytical Chemistry
2022-12-27 | Journal article
Contributors: Katerina V. Djambazova; Martin Dufresne; Lukasz G. Migas; Angela R. S. Kruse; Raf Van de Plas; Richard M. Caprioli; Jeffrey M. Spraggins
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Crossref

Visualizing Staphylococcus aureus pathogenic membrane modification within the host infection environment by multimodal imaging mass spectrometry

Cell Chemical Biology
2022-07 | Journal article
Contributors: William J. Perry; Caroline M. Grunenwald; Raf Van de Plas; James C. Witten; Daniel R. Martin; Suneel S. Apte; James E. Cassat; Gösta B. Pettersson; Richard M. Caprioli; Eric P. Skaar et al.
Source: check_circle
Crossref

Molecular Mapping of Neutral Lipids Using Silicon Nanopost Arrays and TIMS Imaging Mass Spectrometry

Journal of the American Society for Mass Spectrometry
2021-10-06 | Journal article
Contributors: Jarod A. Fincher; Katerina V. Djambazova; Dustin R. Klein; Martin Dufresne; Lukasz G. Migas; Raf Van de Plas; Richard M. Caprioli; Jeffrey M. Spraggins
Source: check_circle
Crossref

Autofluorescence microscopy as a label-free tool for renal histology and glomerular segmentation

2021-07-18 | Other
Contributors: Nathan Heath Patterson; Elizabeth K. Neumann; Kavya Sharman; Jamie Allen; Raymond Harris; Agnes B. Fogo; Mark de Caestecker; Richard M. Caprioli; Raf Van de Plas; Jeffrey M. Spraggins
Source: check_circle
Crossref

Automated Biomarker Candidate Discovery in Imaging Mass Spectrometry Data Through Spatially Localized Shapley Additive Explanations

2020-12-24 | Preprint
Contributors: Leonoor E.M. Tideman; Lukasz G. Migas; Katerina V. Djambazova; Nathan Heath Patterson; Richard M. Caprioli; Jeffrey M. Spraggins; Raf Van de Plas
Source: check_circle
Crossref

Resolving the Complexity of Spatial Lipidomics Using MALDI TIMS Imaging Mass Spectrometry

Analytical Chemistry
2020-10-06 | Journal article
Contributors: Katerina V. Djambazova; Dustin R. Klein; Lukasz G. Migas; Elizabeth K. Neumann; Emilio S. Rivera; Raf Van de Plas; Richard M. Caprioli; Jeffrey M. Spraggins
Source: check_circle
Crossref

Spatial Metabolomics of the Human Kidney using MALDI Trapped Ion Mobility Imaging Mass Spectrometry

Analytical Chemistry
2020-10-06 | Journal article
Contributors: Elizabeth K. Neumann; Lukasz G. Migas; Jamie L. Allen; Richard M. Caprioli; Raf Van de Plas; Jeffrey M. Spraggins
Source: check_circle
Crossref

Resolving the Complexity of Spatial Lipidomics Using MALDI TIMS Imaging Mass Spectrometry

2020-08-18 | Other
Contributors: Katerina Djambazova; Dustin R. Klein; Lukasz Migas; Elizabeth Neumann; Emilio Rivera; Raf Van de Plas; Richard M. Caprioli; Jeffrey Spraggins
Source: check_circle
Crossref

Resolving the Complexity of Spatial Lipidomics Using MALDI TIMS Imaging Mass Spectrometry

2020-08-18 | Other
Contributors: Katerina Djambazova; Dustin R. Klein; Lukasz Migas; Elizabeth Neumann; Emilio Rivera; Raf Van de Plas; Richard M. Caprioli; Jeffrey Spraggins
Source: check_circle
Crossref

Resolving the Complexity of Spatial Lipidomics Using MALDI TIMS Imaging Mass Spectrometry

2020-06-16 | Other
Contributors: Katerina Djambazova; Dustin R. Klein; Lukasz Migas; Elizabeth Neumann; Emilio Rivera; Raf Van de Plas; Richard M. Caprioli; Jeffrey Spraggins
Source: check_circle
Crossref

Resolving the Complexity of Spatial Lipidomics with MALDI Trapped Ion Mobility Spectrometry

2020-05-20 | Preprint
Contributors: Katerina Djambazova; Dustin R. Klein; Lukasz Migas; Elizabeth Neumann; Emilio Rivera; Raf Van de Plas; Richard M. Caprioli; Jeffrey Spraggins
Source: check_circle
Crossref

Discovering New Lipidomic Features Using Cell Type Specific Fluorophore Expression to Provide Spatial and Biological Specificity in a Multimodal Workflow with MALDI Imaging Mass Spectrometry

Analytical Chemistry
2020-05-19 | Journal article
Contributors: Marissa A. Jones; Sung Hoon Cho; Nathan Heath Patterson; Raf Van de Plas; Jeffrey M. Spraggins; Mark R. Boothby; Richard M. Caprioli
Source: check_circle
Crossref

High-Performance Molecular Imaging with MALDI Trapped Ion-Mobility Time-of-Flight (timsTOF) Mass Spectrometry

Analytical Chemistry
2019-11-19 | Journal article
Contributors: Jeffrey M. Spraggins; Katerina V. Djambazova; Emilio S. Rivera; Lukasz G. Migas; Elizabeth K. Neumann; Arne Fuetterer; Juergen Suetering; Niels Goedecke; Alice Ly; Raf Van de Plas et al.
Source: check_circle
Crossref

High Performance Molecular Imaging with MALDI Trapped Ion Mobility Time-of-Flight (timsTOF) Mass Spectrometry

2019-10-02 | Preprint
Contributors: Jeffrey Spraggins; Katerina Djambazova; Emilio Rivera; Lukasz Migas; Elizabeth Neumann; Arne Fuetterer; Juergen Suetering; Niels Goedecke; Alice Ly; Raf Van de Plas et al.
Source: check_circle
Crossref

High Performance Molecular Imaging with MALDI Trapped Ion Mobility Time-of-Flight (timsTOF) Mass Spectrometry

2019-10-02 | Other
Contributors: Jeffrey Spraggins; Katerina Djambazova; Emilio Rivera; Lukasz Migas; Elizabeth Neumann; Arne Fuetterer; Juergen Suetering; Niels Goedecke; Alice Ly; Raf Van de Plas et al.
Source: check_circle
Crossref

High Performance Molecular Imaging with MALDI Trapped Ion Mobility Time-of-Flight (timsTOF) Mass Spectrometry

2019-08-02 | Preprint
Contributors: Jeffrey Spraggins; Katerina Djambazova; Emilio Rivera; Lukasz Migas; Elizabeth Neumann; Arne Fuetterer; Juergen Suetering; Niels Goedecke; Alice Ly; Raf Van de Plas et al.
Source: check_circle
Crossref

Advanced Registration and Analysis of MALDI Imaging Mass Spectrometry Measurements through Autofluorescence Microscopy

Analytical Chemistry
2018-11-06 | Journal article
Contributors: Nathan Heath Patterson; Michael Tuck; Raf Van de Plas; Richard M. Caprioli
Source: check_circle
Crossref

Next Generation Histology-Directed Imaging Mass Spectrometry Driven by Autofluorescence Microscopy

Analytical Chemistry
2018-11-06 | Journal article
Contributors: Nathan Heath Patterson; Michael Tuck; Adam Lewis; Alexis Kaushansky; Jeremy L. Norris; Raf Van de Plas; Richard M. Caprioli
Source: check_circle
Crossref

Enhanced Ion Transmission Efficiency up to m/z 24 000 for MALDI Protein Imaging Mass Spectrometry

Analytical Chemistry
2018-04-17 | Journal article
Contributors: Boone M. Prentice; Daniel J. Ryan; Raf Van de Plas; Richard M. Caprioli; Jeffrey M. Spraggins
Source: check_circle
Crossref

Integrated molecular imaging reveals tissue heterogeneity driving host-pathogen interactions

Science Translational Medicine
2018-03-14 | Journal article
Contributors: James E. Cassat; Jessica L. Moore; Kevin J. Wilson; Zach Stark; Boone M. Prentice; Raf Van de Plas; William J. Perry; Yaofang Zhang; John Virostko; Daniel C. Colvin et al.
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Crossref

Integrated, High-Throughput, Multiomics Platform Enables Data-Driven Construction of Cellular Responses and Reveals Global Drug Mechanisms of Action

Journal of Proteome Research
2017 | Journal article
EID:

2-s2.0-85014609831

Contributors: Norris, J.L.; Farrow, M.A.; Gutierrez, D.B.; Palmer, L.D.; Muszynski, N.; Sherrod, S.D.; Pino, J.C.; Allen, J.L.; Spraggins, J.M.; Lubbock, A.L.R. et al.
Source: Self-asserted source
Raf Van de Plas via Scopus - Elsevier

Connecting imaging mass spectrometry and magnetic resonance imaging-based anatomical atlases for automated anatomical interpretation and differential analysis.

Biochimica et biophysica acta. Proteins and proteomics
2017-02 | Journal article
Contributors: Verbeeck N; Spraggins JM; Murphy MJM; Wang HD; Deutch AY; Caprioli RM; Van de Plas R
Source: Self-asserted source
Raf Van de Plas via Europe PubMed Central

Phospholipid profiling identifies acyl chain elongation as a ubiquitous trait and potential target for the treatment of lung squamous cell carcinoma.

Oncotarget
2016-03 | Journal article
Contributors: Marien E; Meister M; Muley T; Gomez Del Pulgar T; Derua R; Spraggins JM; Van de Plas R; Vanderhoydonc F; Machiels J; Binda MM et al.
Source: Self-asserted source
Raf Van de Plas via Europe PubMed Central

3-D imaging mass spectrometry of protein distributions in mouse Neurofibromatosis 1 (NF1)-associated optic glioma.

Journal of proteomics
2016-02 | Journal article
Contributors: Anderson DM; Van de Plas R; Rose KL; Hill S; Schey KL; Solga AC; Gutmann DH; Caprioli RM
Source: Self-asserted source
Raf Van de Plas via Europe PubMed Central

Non-small cell lung cancer is characterized by dramatic changes in phospholipid profiles.

International journal of cancer
2015-04 | Journal article
Contributors: Marien E; Meister M; Muley T; Fieuws S; Bordel S; Derua R; Spraggins J; Van de Plas R; Dehairs J; Wouters J et al.
Source: Self-asserted source
Raf Van de Plas via Europe PubMed Central

Image fusion of mass spectrometry and microscopy: a multimodality paradigm for molecular tissue mapping

Nature Methods
2015-02 | Journal article
Part of ISSN: 1548-7091
Contributors: Raf Van de Plas; Junhai Yang; Jeffrey Spraggins; Richard M Caprioli
Source: Self-asserted source
Raf Van de Plas via Crossref Metadata Search

Towards automated discrimination of lipids versus peptides from full scan mass spectra.

EuPA open proteomics
2014-09 | Journal article
Contributors: Dittwald P; Nghia VT; Harris GA; Caprioli RM; Van de Plas R; Laukens K; Gambin A; Valkenborg D
Source: Self-asserted source
Raf Van de Plas via Europe PubMed Central

Automated Anatomical Interpretation of Ion Distributions in Tissue: Linking Imaging Mass Spectrometry to Curated Atlases

Analytical Chemistry
2014-08 | Journal article
Part of ISSN: 0003-2700
Contributors: Nico Verbeeck; Junhai Yang; Bart De Moor; Richard M. Caprioli; Etienne Waelkens; Raf Van de Plas
Source: Self-asserted source
Raf Van de Plas via Crossref Metadata Search

Combined mRNA microarray and proteomic analysis of eutopic endometrium of women with and without endometriosis

Human Reproduction
2012 | Journal article
EID:

2-s2.0-84863588059

Contributors: Fassbender, A.; Verbeeck, N.; Brnigen, D.; Kyama, C.M.; Bokor, A.; Vodolazkaia, A.; Peeraer, K.; Tomassetti, C.; Meuleman, C.; Gevaert, O. et al.
Source: Self-asserted source
Raf Van de Plas via Scopus - Elsevier

Proteomics Analysis of Plasma for Early Diagnosis of Endometriosis

Obstetrics & Gynecology
2012-02 | Journal article
Part of ISSN: 0029-7844
Contributors: Amelie Fassbender; Etienne Waelkens; Nico Verbeeck; Cleophas M. Kyama; Attila Bokor; Alexandra Vodolazkaia; Raf Van de Plas; Christel Meuleman; Karen Peeraer; Carla Tomassetti et al.
Source: Self-asserted source
Raf Van de Plas via Crossref Metadata Search

Tensor Versus Matrix Completion: A Comparison With Application to Spectral Data

IEEE Signal Processing Letters
2011-07 | Journal article
Part of ISSN: 1070-9908
Contributors: Marco Signoretto; Raf Van de Plas; Bart De Moor; Johan A. K. Suykens
Source: Self-asserted source
Raf Van de Plas via Crossref Metadata Search

TRIzol treatment of secretory phase endometrium allows combined proteomic and mRNA microarray analysis of the same sample in women with and without endometriosis.

Reproductive Biology and Endocrinology : RB&E
2011-04 | Journal article
Contributors: Fassbender A; Simsa P; Kyama CM; Waelkens E; Mihalyi A; Meuleman C; Gevaert O; Van de Plas R; de Moor B; D'Hooghe TM
Source: Self-asserted source
Raf Van de Plas via Europe PubMed Central

Evaluation of endometrial biomarkers for semi-invasive diagnosis of endometriosis

Fertility and Sterility
2011-03 | Journal article
Part of ISSN: 0015-0282
Contributors: Cleophas M. Kyama; Attila Mihalyi; Olivier Gevaert; Etienne Waelkens; Peter Simsa; Raf Van de Plas; Christel Meuleman; Bart De Moor; Thomas M. D'Hooghe
Source: Self-asserted source
Raf Van de Plas via Crossref Metadata Search

Semi-supervised learning of sparse linear models in mass spectral imaging

Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
2010 | Book
EID:

2-s2.0-78049475294

Contributors: Ojeda, F.; Signoretto, M.; Van De Plas, R.; Waelkens, E.; De Moor, B.; Suykens, J.A.K.
Source: Self-asserted source
Raf Van de Plas via Scopus - Elsevier

TRIzol treatment of secretory phase endometrium allows combined proteomic and mRNA microarray analysis of the same sample in women with and without endometriosis.

Reproductive biology and endocrinology : RB&E
2010-10 | Journal article
Contributors: Fassbender A; Simsa P; Kyama CM; Waelkens E; Mihalyi A; Meuleman C; Gevaert O; Van de Plas R; de Moor B; D'Hooghe TM
Source: Self-asserted source
Raf Van de Plas via Europe PubMed Central

A tutorial on support vector machine-based methods for classification problems in chemometrics

Analytica Chimica Acta
2010-04 | Journal article
Part of ISSN: 0003-2670
Contributors: Jan Luts; Fabian Ojeda; Raf Van de Plas; Bart De Moor; Sabine Van Huffel; Johan A.K. Suykens
Source: Self-asserted source
Raf Van de Plas via Crossref Metadata Search

Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in mice

Proceedings of the National Academy of Sciences of the United States of America
2009 | Journal article
EID:

2-s2.0-70349280000

Contributors: Lemaire, K.; Ravier, M.A.; Schraenen, A.; Creemers, J.W.M.; Van De Plas, R.; Granvik, M.; Van Lommel, L.; Waelkens, E.; Chimienti, F.; Rutter, G.A. et al.
Source: Self-asserted source
Raf Van de Plas via Scopus - Elsevier

The use of laser microdissection and SELDI-TOF MS in ovarian cancer tissue to identify protein profiles

Anticancer Research
2009 | Journal article
EID:

2-s2.0-64949109360

Contributors: Cadron, I.; Van Gorp, T.; Amant, F.; Vergote, I.; Moerman, P.; Waelkens, E.; Daemen, A.; Van De Plas, R.; De Moor, B.; Zeillinger, R.
Source: Self-asserted source
Raf Van de Plas via Scopus - Elsevier

The use of laser microdissection and SELDI-TOF MS in ovarian cancer tissue to identify protein profiles.

Anticancer research
2009-04 | Journal article
Contributors: Cadron I; Van Gorp T; Amant F; Vergote I; Moerman P; Waelkens E; Daemen A; Van De Plas R; De Moor B; Zeillinger R
Source: Self-asserted source
Raf Van de Plas via Europe PubMed Central

Discrete wavelet transform-based multivariate exploration of tissue via imaging mass spectrometry

Proceedings of the 2008 ACM symposium on Applied computing - SAC '08
2008 | Conference paper
Part of ISBN: 9781595937537
Contributors: Raf Van de Plas; Bart De Moor; Etienne Waelkens
Source: Self-asserted source
Raf Van de Plas via Crossref Metadata Search

Prospective exploration of biochemical tissue composition via imaging mass spectrometry guided by principal component analysis

Pacific Symposium on Biocomputing 2007, PSB 2007
2007 | Conference paper
EID:

2-s2.0-38449095009

Contributors: Van De Plas, R.; Ojeda, F.; Dewil, M.; Van Den Bosch, L.; De Moor, B.; Waelkens, E.
Source: Self-asserted source
Raf Van de Plas via Scopus - Elsevier

Imaging mass spectrometry based exploration of biochemical tissue composition using peak intensity weighted PCA

2007 IEEE/NIH Life Science Systems and Applications Workshop
2007-11 | Conference paper
Part of ISBN: 9781424418121
Contributors: Raf Van de Plas; Bart De Moor; Etienne Waelkens
Source: Self-asserted source
Raf Van de Plas via Crossref Metadata Search
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