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Keywords

Cattle, Embryo, Genome editing, Epigenetics, Fertility

Countries

China

Activities

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Employment (3)

Zhejiang Univesity: Hangzhou, Zhejiang, CN

2015-08-31 to present | Principal Investigator (Animal Science and Technology)
Employment
Source: Self-asserted source
Kun Zhang

Michigan State University: East Lansing, Michigan, US

2013-08 to 2015-07 | Assistant Professor (Animal Sciences)
Employment
Source: Self-asserted source
Kun Zhang

University of Massachusetts Amherst: Amherst, MA, US

2011-08 to 2013-07 | Postdoctoral Scholar (Animal and Veterinary Science)
Employment
Source: Self-asserted source
Kun Zhang

Education and qualifications (1)

University of Florida: Gainesville, FL, US

2007-08 to 2011-07 | PhD (Animal Sciences)
Education
Source: Self-asserted source
Kun Zhang

Professional activities (3)

International Embryo Transfer Society: Champaign, IL, US

2017 to present
Membership
Source: Self-asserted source
Kun Zhang

Society for the Study of Reproduction: Madison, Wisconsin, US

2010-08 to present
Membership
Source: Self-asserted source
Kun Zhang

International Embryo Transfer Society: Champaign , IL, US

2021-01 | Domestic Animal Biomedical Embryology Science SLAM Award Runner up
Distinction
Source: Self-asserted source
Kun Zhang

Works (39)

Functional role of GATA3 and CDX2 in lineage specification during bovine early embryonic development.

Reproduction (Cambridge, England)
2023-02-08 | Journal article
DOI: 10.1530/rep-22-0269
PMID: 36630554
PMC: PMC9986393
Contributors: Shi Y; Hu B; Wang Z; Wu X; Luo L; Li S; Wang S; Zhang K; huanan wang
Source: Self-asserted source
Kun Zhang

Linker histone H1FOO is required for bovine preimplantation development by regulating lineage specification and chromatin structure†.

Biology of reproduction
2022-12-01 | Journal article
DOI: 10.1093/biolre/ioac167
PMID: 36001353
Contributors: Li S; Shi Y; Dang Y; Hu B; Xiao L; Zhao P; Wang S; Zhang K
Source: Self-asserted source
Kun Zhang

Base editing in bovine embryos reveals a species-specific role of SOX2 in regulation of pluripotency.

PLoS genetics
2022-07-05 | Journal article | Author
DOI: 10.1371/journal.pgen.1010307
PMID: 35788719
PMC: PMC9286228
Contributors: Lei Luo; Yan Shi; Wang H; Wang Z; yanna dang; Li S; Shaohua Wang; Kun Zhang
Source: Self-asserted source
Kun Zhang

The lysine deacetylase activity of histone deacetylases 1 and 2 is required to safeguard zygotic genome activation in mice and cattle.

Development (Cambridge, England)
2022-06-06 | Journal article | Author
DOI: 10.1242/dev.200854
PMID: 35575026
Contributors: yanna dang; Shuang Li; Panpan Zhao; Lieying Xiao; Lefeng Wang; Yan Shi; Lei Luo; Wang S; Wang H; Kun Zhang
Source: Self-asserted source
Kun Zhang

KDM5-mediated redistribution of H3K4me3 is required for oocyte-to-embryonic transition in cattle†.

Biology of reproduction
2022-06-01 | Journal article
DOI: 10.1093/biolre/ioac047
PMID: 35243485
Contributors: Dang Y; Luo L; Shi Y; Li S; Wang S; Zhang K
Source: Self-asserted source
Kun Zhang

Overlapping functions of RBBP4 and RBBP7 in regulating cell proliferation and histone H3.3 deposition during mouse preimplantation development.

Epigenetics
2021-11-10 | Journal article | Author
DOI: 10.1080/15592294.2021.1999006
PMID: 34709113
PMC: PMC9543047
Contributors: Lieying Xiao; Dang Y; Hu B; Luo L; Panpan Zhao; Wang S; Kun Zhang
Source: Self-asserted source
Kun Zhang

NOTCH signaling pathway is required for bovine early embryonic development

Biology of Reproduction
2021-08-03 | Journal article
DOI: 10.1093/biolre/ioab056
Part of ISSN: 0006-3363
Part of ISSN: 1529-7268
Source: Self-asserted source
Kun Zhang

Functional roles of the chromatin remodeler SMARCA5 in mouse and bovine preimplantation embryos†

Biology of Reproduction
2021-04-23 | Journal article
DOI: 10.1093/biolre/ioab081
Part of ISSN: 0006-3363
Part of ISSN: 1529-7268
Source: Self-asserted source
Kun Zhang
grade
Preferred source (of 2)‎

SIN3A Regulates Porcine Early Embryonic Development by Modulating CCNB1 Expression

Frontiers in Cell and Developmental Biology
2021-02-22 | Journal article
DOI: 10.3389/fcell.2021.604232
Part of ISSN: 2296-634X
Source: Self-asserted source
Kun Zhang

Essential roles of HDAC1 and 2 in lineage development and genome-wide DNA methylation during mouse preimplantation development

Epigenetics
2020-04-02 | Journal article
DOI: 10.1080/15592294.2019.1669375
Part of ISSN: 1559-2294
Part of ISSN: 1559-2308
Source: Self-asserted source
Kun Zhang

The nucleolar protein NOP2 is required for nucleolar maturation and ribosome biogenesis during preimplantation development in mammals

The FASEB Journal
2020-02 | Journal article
DOI: 10.1096/fj.201902623r
Part of ISSN: 0892-6638
Part of ISSN: 1530-6860
Source: Self-asserted source
Kun Zhang

Aminopeptidase N-null neonatal piglets are protected from transmissible gastroenteritis virus but not porcine epidemic diarrhea virus

Scientific Reports
2019-12 | Journal article
DOI: 10.1038/s41598-019-49838-y
Part of ISSN: 2045-2322
Source: Self-asserted source
Kun Zhang

Sin3a regulates the developmental progression through morula‐to‐blastocyst transition via Hdacl

The FASEB Journal
2019-11 | Journal article
DOI: 10.1096/fj.201901213r
Part of ISSN: 0892-6638
Part of ISSN: 1530-6860
Source: Self-asserted source
Kun Zhang

Characterization of H3.3 and HIRA expression and function in bovine early embryos

Molecular Reproduction and Development
2018-02 | Journal article
DOI: 10.1002/mrd.22939
Part of ISSN: 1040-452X
Source: Self-asserted source
Kun Zhang

YY1 Is Required for Posttranscriptional Stability of SOX2 and OCT4 Proteins

Cellular Reprogramming
2017-08 | Journal article
DOI: 10.1089/cell.2017.0002
Part of ISSN: 2152-4971
Part of ISSN: 2152-4998
Source: Self-asserted source
Kun Zhang

Discovery of a novel oocyte-specific Krüppel-associated box domain-containing zinc finger protein required for early embryogenesis in cattle

Mechanisms of Development
2017-04 | Journal article
DOI: 10.1016/j.mod.2017.02.003
Part of ISSN: 0925-4773
Source: Self-asserted source
Kun Zhang

WDR5 in porcine preimplantation embryos: expression, regulation of epigenetic modifications and requirement for early development†

Biology of Reproduction
2017-04 | Journal article
DOI: 10.1093/biolre/iox020
Part of ISSN: 0006-3363
Part of ISSN: 1529-7268
Source: Self-asserted source
Kun Zhang

The requirement for protein kinase C delta (PRKCD) during preimplantation bovine embryo development

Reproduction, Fertility and Development
2016 | Journal article
DOI: 10.1071/rd14160
Part of ISSN: 1031-3613
Source: Self-asserted source
Kun Zhang

Towards Functional Annotation of the Preimplantation Transcriptome: An RNAi Screen in Mammalian Embryos

Scientific Reports
2016-12 | Journal article
DOI: 10.1038/srep37396
Part of ISSN: 2045-2322
Source: Self-asserted source
Kun Zhang

CHD1 Regulates Deposition of Histone Variant H3.3 During Bovine Early Embryonic Development1

Biology of Reproduction
2016-06-01 | Journal article
DOI: 10.1095/biolreprod.116.138693
Part of ISSN: 0006-3363
Part of ISSN: 1529-7268
Source: Self-asserted source
Kun Zhang

Nop2 is required for mammalian preimplantation development

Molecular Reproduction and Development
2016-02 | Journal article
DOI: 10.1002/mrd.22600
Part of ISSN: 1040-452X
Source: Self-asserted source
Kun Zhang

Maternal control of early embryogenesis in mammals

Reproduction, Fertility and Development
2015 | Journal article
DOI: 10.1071/rd14441
Part of ISSN: 1031-3613
Source: Self-asserted source
Kun Zhang

Evidence Supporting a Role for SMAD2/3 in Bovine Early Embryonic Development: Potential Implications for Embryotropic Actions of Follistatin1

Biology of Reproduction
2015-10-01 | Journal article
DOI: 10.1095/biolreprod.115.130278
Part of ISSN: 0006-3363
Part of ISSN: 1529-7268
Source: Self-asserted source
Kun Zhang

Expression of TGFβ superfamily components and other markers of oocyte quality in oocytes selected by brilliant cresyl blue staining: Relevance to early embryonic development

Molecular Reproduction and Development
2015-03 | Journal article
DOI: 10.1002/mrd.22468
Part of ISSN: 1040-452X
Source: Self-asserted source
Kun Zhang

Mga is essential for the survival of pluripotent cells during peri-implantation development

Development
2015-01-01 | Journal article
DOI: 10.1242/dev.111104
Part of ISSN: 1477-9129
Part of ISSN: 0950-1991
Source: Self-asserted source
Kun Zhang

Evidence Supporting a Functional Requirement of SMAD4 for Bovine Preimplantation Embryonic Development: A Potential Link to Embryotrophic Actions of Follistatin1

Biology of Reproduction
2014-09-01 | Journal article
DOI: 10.1095/biolreprod.114.120105
Part of ISSN: 0006-3363
Part of ISSN: 1529-7268
Source: Self-asserted source
Kun Zhang

Functional Role of the Bovine Oocyte-Specific Protein JY-1 in Meiotic Maturation, Cumulus Expansion, and Subsequent Embryonic Development1

Biology of Reproduction
2014-03-01 | Journal article
DOI: 10.1095/biolreprod.113.115071
Part of ISSN: 0006-3363
Part of ISSN: 1529-7268
Source: Self-asserted source
Kun Zhang

CTR9/PAF1c regulates molecular lineage identity, histone H3K36 trimethylation and genomic imprinting during preimplantation development

Developmental Biology
2013-11 | Journal article
DOI: 10.1016/j.ydbio.2013.09.005
Part of ISSN: 0012-1606
Source: Self-asserted source
Kun Zhang

A novel promoterless gene targeting vector to efficiently disrupt PRNP gene in cattle

Journal of Biotechnology
2013-02 | Journal article
DOI: 10.1016/j.jbiotec.2012.10.018
Part of ISSN: 0168-1656
Source: Self-asserted source
Kun Zhang

Depletion of Suds3 reveals an essential role in early lineage specification

Developmental Biology
2013-01 | Journal article
DOI: 10.1016/j.ydbio.2012.10.026
Part of ISSN: 0012-1606
Source: Self-asserted source
Kun Zhang

Disruption of fibroblast growth factor receptor signaling in bovine cumulus-oocyte complexes during in vitro maturation reduces subsequent embryonic development

Domestic Animal Endocrinology
2012-05 | Journal article
DOI: 10.1016/j.domaniend.2011.12.006
Part of ISSN: 0739-7240
Source: Self-asserted source
Kun Zhang

Fibroblast Growth Factor 2 Promotes Primitive Endoderm Development in Bovine Blastocyst Outgrowths1

Biology of Reproduction
2011-11-01 | Journal article
DOI: 10.1095/biolreprod.111.093203
Part of ISSN: 0006-3363
Part of ISSN: 1529-7268
Source: Self-asserted source
Kun Zhang

Fibroblast growth factor 10 enhances bovine oocyte maturation and developmental competence in vitro

REPRODUCTION
2010-12 | Journal article
DOI: 10.1530/rep-10-0190
Part of ISSN: 1470-1626
Part of ISSN: 1741-7899
Source: Self-asserted source
Kun Zhang

Knockdown of the prion gene expression by RNA interference in bovine fibroblast cells

Molecular Biology Reports
2010-10 | Journal article
DOI: 10.1007/s11033-009-9900-0
Part of ISSN: 0301-4851
Part of ISSN: 1573-4978
Source: Self-asserted source
Kun Zhang

Stage-dependent Effect of Leptin on Development of Porcine Embryos Derived from Parthenogenetic Activation and Transgenic Somatic Cell Nuclear Transfer

Journal of Reproduction and Development
2009 | Journal article
DOI: 10.1262/jrd.19167
Part of ISSN: 0916-8818
Part of ISSN: 1348-4400
Source: Self-asserted source
Kun Zhang

Removal of selectable marker gene from fibroblast cells in transgenic cloned cattle by transient expression of Cre recombinase and subsequent effects on recloned embryo development

Theriogenology
2009-09 | Journal article
DOI: 10.1016/j.theriogenology.2009.04.009
Part of ISSN: 0093-691X
Source: Self-asserted source
Kun Zhang

Effects of chemical activation and season on birth efficiency of cloned pigs

Science in China Series C: Life Sciences
2009-07 | Journal article
DOI: 10.1007/s11427-009-0087-3
Part of ISSN: 1006-9305
Part of ISSN: 1862-2798
Source: Self-asserted source
Kun Zhang

Effects of Ghrelin on In Vitro Development of Porcine In Vitro Fertilized and Parthenogenetic Embryos

Journal of Reproduction and Development
2007 | Journal article
DOI: 10.1262/jrd.18140
Part of ISSN: 0916-8818
Part of ISSN: 1348-4400
Source: Self-asserted source
Kun Zhang

Effects of leptin supplementation in in vitro maturation medium on meiotic maturation of oocytes and preimplantation development of parthenogenetic and cloned embryos in pigs

Animal Reproduction Science
2007-09 | Journal article
DOI: 10.1016/j.anireprosci.2006.08.021
Part of ISSN: 0378-4320
Source: Self-asserted source
Kun Zhang
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