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Works (17)

Kidney Volume and Risk of Incident Kidney Outcomes

Journal of the American Society of Nephrology
2024-09 | Journal article
DOI: 10.1681/ASN.0000000000000419
Contributors: Jianhan Wu; Yifan Wang; Caitlyn Vlasschaert; Ricky Lali; James Feiner; Pukhraj Gaheer; Serena Yang; Nicolas Perrot; Michael Chong; Guillaume Paré et al.
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The circulating proteome and brain health: Mendelian randomisation and cross-sectional analyses

Translational Psychiatry
2024-05-18 | Journal article
DOI: 10.1038/s41398-024-02915-x
Contributors: Rosie M. Walker; Michael Chong; Nicolas Perrot; Marie Pigeyre; Danni A. Gadd; Aleks Stolicyn; Liu Shi; Archie Campbell; Xueyi Shen; Heather C. Whalley et al.
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Spatial Multi-Omics Connect SHROOM3 and COL18A1 in Chronic Kidney Disease

2024-02-11 | Preprint
DOI: 10.1101/2024.02.09.24301246
Contributors: Pukhraj S. Gaheer; Nikhil Uppal; Amy Paul; Pedrum Mohammadi-Shemirani; Nicolas Perrot; Guillaume Paré; Darren Bridgewater; Matthew B. Lanktree
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The circulating proteome and brain health: Mendelian randomisation and cross-sectional analyses

2023-10-03 | Preprint
DOI: 10.21203/rs.3.rs-3029765/v1
Contributors: Rosie Walker; Michael Chong; Nicolas Perrot; Marie Pigeyre; Danni Gadd; Aleks Stolicyn; Liu Shi; Heather Whalley; Alejo Nevado-Holgado; Andrew McIntosh et al.
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A versatile, fast and unbiased method for estimation of gene-by-environment interaction effects on biobank-scale datasets

Nature Communications
2023-08-25 | Journal article
DOI: 10.1038/s41467-023-40913-7
Contributors: Matteo Di Scipio; Mohammad Khan; Shihong Mao; Michael Chong; Conor Judge; Nazia Pathan; Nicolas Perrot; Walter Nelson; Ricky Lali; Shuang Di et al.
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Prognostic Utility of Total Kidney Volume for Chronic Kidney Disease Risk Prediction: An Observational and Mendelian Randomization Study

2023-08-24 | Preprint
DOI: 10.1101/2023.08.23.23294447
Contributors: Jianhan Wu; Yifan Wang; Caitlyn Vlasschaert; Ricky Lali; James Feiner; Pukhraj Gaheer; Serena Yang; Nicolas Perrot; Michael Chong; Matthew B. Lanktree et al.
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The circulating proteome and brain health: Mendelian randomisation and cross-sectional analyses

2023-07-31 | Preprint
DOI: 10.1101/2023.07.27.23293236
Contributors: Rosie May Walker; Michael Chong; Nicolas Perrot; Marie Pigeyre; Danni A Gadd; Aleks Stolicyn; Liu Shi; Archie Campbell; Xueyi Shen; Heather C Whalley et al.
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Polygenic Risk Score for Coronary Artery Disease Improves the Prediction of Early-Onset Myocardial Infarction and Mortality in Men

Circulation: Genomic and Precision Medicine
2021-12 | Journal article
DOI: 10.1161/CIRCGEN.121.003452
Contributors: Hasanga D. Manikpurage; Aida Eslami; Nicolas Perrot; Zhonglin Li; Christian Couture; Patrick Mathieu; Yohan Bossé; Benoit J. Arsenault; Sébastien Thériault
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Electronic health record-based genome-wide meta-analysis provides insights on the genetic architecture of non-alcoholic fatty liver disease

Cell Reports Medicine
2021-11 | Journal article
DOI: 10.1016/j.xcrm.2021.100437
Contributors: Nooshin Ghodsian; Erik Abner; Connor A. Emdin; Émilie Gobeil; Nele Taba; Mary E. Haas; Nicolas Perrot; Hasanga D. Manikpurage; Éloi Gagnon; Jérôme Bourgault et al.
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Sex-Specific Associations of Genetically Predicted Circulating Lp(a) (Lipoprotein(a)) and Hepatic LPA Gene Expression Levels With Cardiovascular Outcomes: Mendelian Randomization and Observational Analyses

Circulation: Genomic and Precision Medicine
2021-08 | Journal article
DOI: 10.1161/CIRCGEN.120.003271
Contributors: Jakie Guertin; Yannick Kaiser; Hasanga Manikpurage; Nicolas Perrot; Raphaëlle Bourgeois; Christian Couture; Nicholas J. Wareham; Yohan Bossé; Philippe Pibarot; Erik S.G. Stroes et al.
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Circulating Galectin-3 Levels Are Not Associated With Nonalcoholic Fatty Liver Disease: A Mendelian Randomization Study

The Journal of Clinical Endocrinology & Metabolism
2021-07-13 | Journal article
DOI: 10.1210/clinem/dgab144
Contributors: Maxime Tremblay; Nicolas Perrot; Nooshin Ghodsian; Émilie Gobeil; Christian Couture; Patricia L Mitchell; Sébastien Thériault; Benoit J Arsenault
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A Polygenic Risk Score for Coronary Artery Disease Improves the Prediction of Early-Onset Myocardial Infarction and Mortality in Men

2021-04-27 | Preprint
DOI: 10.1101/2021.04.25.21256083
Contributors: Hasanga D. Manikpurage; Aida Eslami; Nicolas Perrot; Zhonglin Li; Christian Couture; Patrick Mathieu; Yohan Bossé; Benoit J. Arsenault; Sébastien Thériault
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A versatile, fast and unbiased method for estimation of gene-by-environment interaction effects on biobank-scale datasets

2021-04-27 | Preprint
DOI: 10.1101/2021.04.24.21255884
Contributors: Mohammad Khan; Matteo Di Scipio; Conor Judge; Nicolas Perrot; Michael Chong; Shihong Mao; Shuang Di; Walter Nelson; Jeremy Petch; Guillaume Paré
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Lipoprotein-associated phospholipase A2 activity, genetics and calcific aortic valve stenosis in humans

Heart
2020-09 | Journal article
DOI: 10.1136/heartjnl-2020-316722
Contributors: Nicolas Perrot; Sébastien Thériault; Sidwell Rigade; Hao Yu Chen; Christian Dina; Andreas Martinsson; S Matthijs Boekholdt; Romain Capoulade; Thierry Le Tourneau; David Messika-Zeitoun et al.
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A Trans-Omic Mendelian Randomization Study of Parental Lifespan Uncovers Novel Aging Biology and Drug Candidates for Human Healthspan Extension

2020-07-10 | Preprint
DOI: 10.1101/2020.07.06.20147520
Contributors: Nicolas Perrot; William Pelletier; Jerome Bourgeault; Christian Couture; Zhonglin Li; Patricia Mitchell; Nooshin Ghodsian; Yohan Bosse; Sebastien Theriault; Patrick Mathieu et al.
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Life's simple 7 and calcific aortic valve stenosis incidence in apparently healthy men and women

International Journal of Cardiology
2018-10 | Journal article
DOI: 10.1016/j.ijcard.2018.07.107
Contributors: Nicolas Perrot; S. Matthijs Boekholdt; Patrick Mathieu; Nicholas J. Wareham; Kay-Tee Khaw; Benoit J. Arsenault
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Ideal cardiovascular health influences cardiovascular disease risk associated with high lipoprotein(a) levels and genotype: The EPIC-Norfolk prospective population study

Atherosclerosis
2017-01 | Journal article
DOI: 10.1016/j.atherosclerosis.2016.11.010
Contributors: Nicolas Perrot; Rutger Verbeek; Manjinder Sandhu; S. Matthijs Boekholdt; G. Kees Hovingh; Nicholas J. Wareham; Kay-Tee Khaw; Benoit J. Arsenault
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